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Iranian Journal of Kidney Diseases Jan 2011INTRODUCTION. This study was conducted to evaluate the sensitivity and specificity of pyuria detection in centrifuged urine samples of patients on hemodialysis, and its...
INTRODUCTION. This study was conducted to evaluate the sensitivity and specificity of pyuria detection in centrifuged urine samples of patients on hemodialysis, and its relationship with urinary tract infection. MATERIALS AND METHODS. Clean-catch midstream urine samples of 90 hemodialysis patients (34 women and 56 men) were obtained and divided into two parts for examination of urine sediment and urine culture. Pyuria was defined as the presence of more than 10 leukocytes per high-power field of microscope. RESULTS. Ninety patients with a mean age of 52.8 ± 14.2 and a mean period of dialysis of 3.3 ± 2.3 years were studied. Forty-five participants had pyuria and only 16 (35.5%) of them had a positive urine culture for infection. Pyuria and urinary tract infection were present in 52.9% and 29.4% of the women and 48.2% and 10.7% of the men, respectively. The sensitivity and specificity of pyuria screening for urinary tract infection was 100% and 61.8%, respectively. The positive and negative predictive values were 35.5% and 100%, respectively. CONCLUSIONS. In patients on hemodialysis, because of the low specificity and positive predictive values, samples with positive pyuria should be cultured to confirm urinary tract infections.
Topics: Adult; Aged; Aged, 80 and over; Female; Humans; Male; Middle Aged; Predictive Value of Tests; Pyuria; Renal Dialysis; Sensitivity and Specificity; Urinalysis; Urinary Tract Infections
PubMed: 21189435
DOI: No ID Found -
Infection 1994The reliability of two methods for the detection of pyuria was studied in a total of 106 urine samples obtained from patients with identifiable underlying urinary tract... (Comparative Study)
Comparative Study
The reliability of two methods for the detection of pyuria was studied in a total of 106 urine samples obtained from patients with identifiable underlying urinary tract disease. The coefficient of variation (CV) was significantly higher in the microscopic than in the counting chamber method. The CV obtained with the use of the KOVA slide 10 grid, a disposable and less expensive counting chamber, was identical to that obtained with the Bürker-Türk counting chamber. Only 50% of the patients who were proven to have pyuria of > or = 5 WBCs/HPF by the microscopic method had significant bacteriuria of > or = 10(4) bacteria per ml of urine. On the other hand, 95% and 90% of the patients who were proven to have pyuria of > or = 10 WBCs/mm3 with the Bürker-Türk and Fuchs-Rosenthal counting chambers had significant bacteriuria. It was concluded that the counting chamber provides a reliable method for the detection of pyuria and is highly predictive for the presence of significant bacteriuria. The KOVA slide 10 grid is an acceptable alternative to the regular counting chamber.
Topics: Adult; Aged; Aged, 80 and over; Analysis of Variance; Female; Humans; Leukocyte Count; Male; Middle Aged; Prostatic Hyperplasia; Pyuria; Reproducibility of Results; Urinary Bladder Neoplasms; Urinary Bladder, Neurogenic
PubMed: 7519582
DOI: 10.1007/BF01716039 -
Annals of Internal Medicine Mar 1989
Topics: Aged; Aged, 80 and over; Bacteriuria; Female; Humans; Predictive Value of Tests; Pyuria
PubMed: 2916809
DOI: 10.7326/0003-4819-110-5-404 -
The Nebraska State Medical Journal Sep 1952
Topics: Pyuria; Urologic Diseases
PubMed: 13002472
DOI: No ID Found -
Medical Times Oct 1948
Topics: Child; Humans; Pyuria; Urinary Tract Infections
PubMed: 18121678
DOI: No ID Found -
The American Journal of Emergency... Oct 2017
Topics: Bacteria; Bacteriuria; Humans; Pyuria; Urinary Tract Infections
PubMed: 28760381
DOI: 10.1016/j.ajem.2017.07.060 -
International Urology and Nephrology Mar 2024Asymptomatic pyuria and bacteriuria are more prevalent in diabetic patients and may be associated with urinary tract infection (UTI). The aim of this study is to...
PURPOSE
Asymptomatic pyuria and bacteriuria are more prevalent in diabetic patients and may be associated with urinary tract infection (UTI). The aim of this study is to investigate the association between asymptomatic pyuria/bacteriuria at the initiation of SGLT2 inhibitor and UTI risk in female patients with type 2 diabetes.
METHODS
The study was designed as a practical, single-center, prospective, cohort study. The female outpatients with type 2 diabetes initiated SGLT2 inhibitor were included. Patients who were symptomatic or treated in the past 3 months for urinary or genital tract infection, had a high risk for UTI were excluded. Hospitalization/antibiotic use for indications other than UTI were exclusion criteria during follow-up. All patients were followed up for 3 months. Pyuria and bacteriuria were exposure and, UTI was the outcome. Cumulative incidence and relative risk of UTI were analyzed for pyuria and bacteriuria.
RESULTS
143 female patients were included among 1132 female type 2 diabetic patients. 13 patients were excluded during follow-up. 41.5% of the patients (n = 54) had pyuria and 28.5% (n = 37) had bacteriuria. The cumulative incidence of UTI was 20% in the whole cohort, 25,9% (n = 14/54) in the pyuria group and 18.9% (n = 7/37) in the bacteriuria group. The relative risk of UTI was 1.64 (95% CI: 0.82-3.26, p = 0.15) for pyuria, 0.92 (95% CI: 0.42-2.01, p = 0.84) for bacteriuria, and 1.2 (95% CI: 0.47-3.08, p = 0.69) for pyuria plus bacteriuria. Adjusted odd ratios revealed similar results.
CONCLUSIONS
Asymptomatic pyuria/bacteriuria at the initiation of SGLT2 inhibitors are not risk factors for UTI in women with type 2 diabetes.
Topics: Female; Humans; Bacteriuria; Cohort Studies; Diabetes Mellitus, Type 2; Prospective Studies; Pyuria; Sodium-Glucose Transporter 2 Inhibitors; Urinary Tract Infections; Asymptomatic Infections
PubMed: 37715859
DOI: 10.1007/s11255-023-03798-5 -
Journal of Nippon Medical School =... Oct 2001The aim of the present study was to determine the prevalence of and the host factors for asymptomatic pyuria (ASP) in women with type 2 diabetes. The study included 179...
The aim of the present study was to determine the prevalence of and the host factors for asymptomatic pyuria (ASP) in women with type 2 diabetes. The study included 179 type 2 diabetic women and consecutive 455 non-diabetic women attending as out-patients in 1996. Patients with symptoms of a urinary tract infection were excluded. ASP was defined as the presence of more than 10 leukocytes/high-power field in a random urine sample. Diabetic women more often had ASP than non-diabetic women (27.9 vs. 15.8%, P<0.001). The prevalence of ASP was significantly increased in patients with a duration of diabetes exceeding 15 years (0 approximately 4 years; 20.3%, 5 approximately 9 years; 24.3%, 10 approximately 14 years; 23.8%, and > or =15 years; 46.3%). No differences were evident in HbA(1C) between diabetic patients without ASP and those with ASP. Diabetic women with ASP more often had diabetic retinopathy, neuropathy, nephropathy, cerebrovascular disease, ischemic heart disease, and hyperlipidemia than those without ASP. However, no statistically significant differences were evident in the prevalence of hypertension, constipation, or dementia. As the degree of neuropathy increases, it is accompanied by an increasing prevalence of ASP (none, 21.4%; blunt tendon reflexes, 24.5%; symptomatic, 50.0%; and gangrene, 66.6%). The prevalence of ASP was significantly increased in the patients with proliferative diabetic retinopathy (none, 23.2%; background, 29.4%; pre-proliferative, 18.2%; and proliferative, 50.0%). As the degree of nephropathy increases, it is accompanied by an increasing prevalence of ASP (none, 20.0%; microalbuminuria, 31.9%; macroalbuminuria, 37.0%; and renal failure, 60.0%). Thus, the prevalence of ASP is increased in women with diabetes and increased with longer duration of diabetes but was not affected by glucose control. The incidence of ASP increases significantly as diabetic microangiopathy becomes severer.
Topics: Aged; Diabetes Mellitus, Type 2; Female; Humans; Middle Aged; Pyuria
PubMed: 11598624
DOI: 10.1272/jnms.68.405 -
American Journal of Clinical Pathology Sep 1963
Topics: Biomedical Technology; Clinical Laboratory Techniques; Humans; Laboratories; Medical Laboratory Science; Pyuria
PubMed: 14063692
DOI: 10.1093/ajcp/40.3.276 -
Virginia Medical Monthly Jan 1951
Topics: Humans; Pyuria; Urinary Tract
PubMed: 14798812
DOI: No ID Found