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Journal of Clinical Pathology Mar 1984
Topics: Female; Humans; Mycobacterium tuberculosis; Pyuria; Tuberculosis, Urogenital
PubMed: 6421897
DOI: 10.1136/jcp.37.3.355-a -
Wiener Klinische Wochenschrift Aug 1968
Topics: Acute Disease; Adolescent; Age Factors; Anti-Bacterial Agents; Child; Child, Preschool; Chloramphenicol; Chronic Disease; Female; Humans; Infant; Infant, Newborn; Male; Nitrofurantoin; Pyuria; Sex Factors; Sulfonamides; Urinary Tract Infections; Urine; Urogenital Abnormalities
PubMed: 5704257
DOI: No ID Found -
Ceskoslovenska Pediatrie Mar 1960
Topics: Child; Humans; Infant; Pyuria
PubMed: 13807581
DOI: No ID Found -
Wiener Klinische Wochenschrift Aug 1968
Topics: Bacteriuria; Child, Preschool; Chloramphenicol; Chronic Disease; Female; Humans; Infant; Infant, Newborn; Male; Nitrofurantoin; Pyelonephritis; Pyuria; Sex Factors; Sulfonamides; Urinary Tract Infections
PubMed: 5760065
DOI: No ID Found -
Pediatrics Nov 2016Varying urine white blood cell (WBC) thresholds have been recommended for the presumptive diagnosis of urinary tract infection (UTI) among young infants. These...
BACKGROUND
Varying urine white blood cell (WBC) thresholds have been recommended for the presumptive diagnosis of urinary tract infection (UTI) among young infants. These thresholds have not been studied with newer automated urinalysis systems that analyze uncentrifuged urine that might be influenced by urine concentration. Our objective was to determine the optimal urine WBC threshold for UTI in young infants by using an automated urinalysis system, stratified by urine concentration.
METHODS
Retrospective cross-sectional study of infants aged <3 months evaluated for UTI in the emergency department with paired urinalysis and urine culture. UTI was defined as ≥50 000 colony-forming units/mL from catheterized specimens. Test characteristics were calculated across a range of WBC and leukocyte esterase (LE) cut-points, dichotomized into specific gravity groups (dilute <1.015; concentrated ≥1.015).
RESULTS
Twenty-seven thousand infants with a median age of 1.7 months were studied. UTI prevalence was 7.8%. Optimal WBC cut-points were 3 WBC/high-power field (HPF) in dilute urine (likelihood ratio positive [LR+] 9.9, likelihood ratio negative [LR‒] 0.15) and 6 WBC/HPF (LR+ 10.1, LR‒ 0.17) in concentrated urine. For dipstick analysis, positive LE has excellent test characteristics regardless of urine concentration (LR+ 22.1, LR‒ 0.12 in dilute urine; LR+ 31.6, LR‒ 0.22 in concentrated urine).
CONCLUSIONS
Urine concentration should be incorporated into the interpretation of automated microscopic urinalysis in young infants. Pyuria thresholds of 3 WBC/HPF in dilute urine and 6 WBC/HPF in concentrated urine are recommended for the presumptive diagnosis of UTI. Without correction of specific gravity, positive LE by automated dipstick is a reliably strong indicator of UTI.
Topics: Academic Medical Centers; Area Under Curve; Automation; Confidence Intervals; Cross-Sectional Studies; Female; Hospitals, Pediatric; Humans; Infant; Infant, Newborn; Leukocyte Count; Leukocytes; Male; Predictive Value of Tests; Pyuria; ROC Curve; Retrospective Studies; Urinalysis; Urinary Tract Infections
PubMed: 27940788
DOI: 10.1542/peds.2016-2370 -
Duodecim; Laaketieteellinen... 1972
Topics: Bacteriophage Typing; Bacteriuria; Humans; L Forms; Leukocyte Count; Pyelonephritis; Pyuria; Urinary Tract Infections
PubMed: 5040783
DOI: No ID Found -
International Journal of Urology :... Nov 2020To evaluate the relationship between residual urine volume, pyuria and bladder carcinoma recurrence.
OBJECTIVES
To evaluate the relationship between residual urine volume, pyuria and bladder carcinoma recurrence.
METHODS
The clinical data of 305 patients who had post-void residual urine volume measured and preoperative pyuria were retrospectively collected. The patients were classified into three risk groups based on the presence of residual urine and pyuria: good (negative residual urine and pyuria), intermediate (positive residual urine or pyuria) and poor (positive residual urine and pyuria). Predictive factors for intravesical recurrence-free survival were statistically analyzed using Cox proportional hazard models and Kaplan-Meier methods. The propensity score matching method was used to adjust the patients' backgrounds.
RESULTS
The median follow-up period for all patients was 44 months. The presence of residual urine (P = 0.0164) and pyuria (P = 0.0233) were two independent prognostic factors for recurrence. After patients were classified into risk groups, the poor-risk group showed significantly shorter recurrence-free survival compared with that of the good- (P = 0.0002) and intermediate-risk groups (P = 0.0090). Even after matching, the presence of residual urine was related to short recurrence-free survival in male patients (P = 0.0012). When stratified by European Organization for Research and Treatment of Cancer risk groups, the presence of pyuria was related to short recurrence-free survival, especially for intermediate-risk patients without bacillus Calmette-Guérin treatment.
CONCLUSIONS
Post-void residual urine and preoperative pyuria are two risks for recurrence-free survival in non-muscle-invasive bladder cancer.
Topics: Administration, Intravesical; BCG Vaccine; Carcinoma; Humans; Male; Neoplasm Recurrence, Local; Pyuria; Retrospective Studies; Urinary Bladder Neoplasms
PubMed: 32875619
DOI: 10.1111/iju.14352 -
Acta Medica Scandinavica Dec 1973
Comparative Study
Topics: Centrifugation; Evaluation Studies as Topic; Humans; Hydrogen-Ion Concentration; Leukocyte Count; Methods; Pyuria; Specimen Handling; Staining and Labeling
PubMed: 4129779
DOI: No ID Found -
Lupus 2001Hematuria or sterile pyuria as isolated urinary findings present a clinical dilemma for the treating physician. Our objective was to determine whether isolated hematuria...
Hematuria or sterile pyuria as isolated urinary findings present a clinical dilemma for the treating physician. Our objective was to determine whether isolated hematuria and isolated sterile pyuria are associated with active systemic lupus erythematosus (SLE) with respect to renal and non-renal disease activity. This is a descriptive study from a large SLE cohort followed prospectively at the University of Toronto Lupus Clinic. All episodes of isolated hematuria and isolated pyuria between 1970 and 2000 were identified from our database. Isolated hematuria was defined as > 5 red blood cells per high power field; isolated sterile pyuria was defined as > 5 white blood cells per high power field in the absence of urinary infection and other renal manifestations. Non-renal disease activity (defined as nrSLEDAI > 1) was determined at first episode of isolated hematuria and pyuria. Renal disease activity was assessed by scoring renal biopsies within 3 months of detecting isolated hematuria or sterile pyuria. Thirty-four percent (323/946) of our cohort had at least one episode of isolated hematuria. Seventy-seven percent of these patients had concurrent non-renal disease activity. Of the 22 biopsies scored with isolated hematuria, 96% were abnormal (WHO > class I), including 52% with active nephritis. Twenty-three percent (215/946) had at least one episode of isolated sterile pyuria. Seventy-eight percent of these patients had concurrent non-renal disease activity. All 12 biopsies scored with isolated pyuria were abnormal (WHO Class > 1), including 75% with active nephritis. The appearance of isolated hematuria and isolated pyuria is associated with active renal and non-renal disease activity. An ongoing debate has emerged regarding the significance of isolated hematuria and isolated pyuria with respect to SLE disease activity. The results of this study suggest that isolated hematuria and isolated pyuria is associated with active renal and non-renal disease activity. Thus isolated hematuria and isolated sterile pyuria should be considered manifestations of active SLE.
Topics: Biopsy; Hematuria; Humans; Kidney; Lupus Erythematosus, Systemic; Prospective Studies; Pyuria
PubMed: 11434577
DOI: 10.1191/096120301678646164 -
Urologic Nursing Dec 2003The purpose of this study was to determine whether pressing a dipstick into a pad within 2 hours of urine saturation detected pyuria as effectively as immersing a...
The purpose of this study was to determine whether pressing a dipstick into a pad within 2 hours of urine saturation detected pyuria as effectively as immersing a dipstick in a urine specimen. Sensitivity, specificity, and positive and negative predictive values indicated that results of the pad method were as effective as those of direct dipstick into clean-catch urine in detecting pyuria. In the elderly, sensitivity of the pad method was 100%, indicating this would be an effective method for initial assessment of pyuria.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Female; Humans; Incontinence Pads; Male; Middle Aged; Pyuria; Urinary Incontinence
PubMed: 14725159
DOI: No ID Found