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Seminars in Urologic Oncology Nov 1995Renal adenoma and oncocytoma are relatively common, benign solid renal tumors. These lesions rarely present with specific genitourinary symptoms and are most often... (Review)
Review
Renal adenoma and oncocytoma are relatively common, benign solid renal tumors. These lesions rarely present with specific genitourinary symptoms and are most often incidentally detected as small renal masses. While some radiologic findings are suggestive of either lesion, there are no pathognomonic radiologic features that can dependably differentiate them from renal cell carcinoma. Renal adenoma is often histologically indistinguishable from renal cell carcinoma, and renal oncocytoma shares many cellular features with granular renal cell carcinoma, thereby limiting the utility of needle biopsy or aspiration cytology for diagnosis. These tumors are also often found associated with renal cell carcinoma in the same or contralateral kidney, so that surgical excision is the only reliable means to achieve both definitive diagnosis and treatment.
Topics: Adenoma; Adenoma, Oxyphilic; Carcinoma, Renal Cell; Diagnosis, Differential; Female; Humans; Kidney Neoplasms; Male; Nephrectomy; Prognosis; Tomography, X-Ray Computed
PubMed: 8595549
DOI: No ID Found -
European Urology 1983
Topics: Adenoma; Female; Humans; Kidney Neoplasms; Male; Radiography
PubMed: 6822238
DOI: 10.1159/000474035 -
Ryoikibetsu Shokogun Shirizu 1997
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The Journal of Urology Jul 1996We evaluated the outcome of nephrogenic adenoma, a benign tumor rarely encountered in renal transplant recipients. (Review)
Review
PURPOSE
We evaluated the outcome of nephrogenic adenoma, a benign tumor rarely encountered in renal transplant recipients.
MATERIALS AND METHODS
Between 1985 and 1993, 9 renal transplant recipients with a nephrogenic bladder adenoma removed by endoscopic resection were followed for 24 to 88 months (mean 40). Tumor deoxyribonucleic acid ploidy was assessed by flow cytometry at diagnosis and/or relapse.
RESULTS
The relapse rate was 88%. The tumors were diploid and of low proliferating potential, and showed no malignant transformation.
CONCLUSIONS
Our study confirms the lack of premalignant potential of nephrogenic adenomas. However, since transplant recipients might be at increased risk for bladder cancer, they should be followed closely.
Topics: Adenoma; Adult; DNA, Neoplasm; Female; Follow-Up Studies; Humans; Kidney Transplantation; Male; Middle Aged; Ploidies; Time Factors; Urinary Bladder Neoplasms
PubMed: 8648834
DOI: 10.1016/s0022-5347(01)65932-9 -
Urologia Internationalis 1980At the Department of Urology, University of Mainz Medical School, 286 patients were operated between 1967 and 1976 for alleged renal cell carcinoma. In 7 patients (2.4%)... (Review)
Review
At the Department of Urology, University of Mainz Medical School, 286 patients were operated between 1967 and 1976 for alleged renal cell carcinoma. In 7 patients (2.4%) a renal adenoma was diagnosed. A search in the pertinent literature revealed among patients treated for renal tumors an incidence between 0.21 and 4.4%. There is no reliable preoperative test to distinguish clinically between renal cell carcinoma and adenoma. Even intraoperative frozen section does not safely rule out the possibility of malignant degeneration. Thus, tumor-nephrectomy remains the treatment of choice. Partial resection is warranted only in solitary kidneys, as supported by 2 own cases. Eventually, malignant change and dissemination occurs. Histologically, the renal adenomas are therefore classified as G0 tumors.
Topics: Adenocarcinoma; Adenoma; Aged; Diagnosis, Differential; Female; Humans; Kidney Neoplasms; Male; Middle Aged; Nephrectomy; Prognosis
PubMed: 6994314
DOI: 10.1159/000280331 -
Journal de Radiologie Apr 2001Renal oncocytic adenoma. Renal oncocytic adenoma is a rare neoplasm now considered as a benign tumour. The purpose of this paper is to describe the radiological features... (Review)
Review
Renal oncocytic adenoma. Renal oncocytic adenoma is a rare neoplasm now considered as a benign tumour. The purpose of this paper is to describe the radiological features of this tumour and to assess the value of imaging work-up in the diagnosis and management of patients with renal oncocytic adenomas.
Topics: Adenoma, Oxyphilic; Angiography; Biopsy; Diagnosis, Differential; Humans; Kidney Neoplasms; Magnetic Resonance Imaging; Tomography, X-Ray Computed; Ultrasonography, Doppler; Urography
PubMed: 11353900
DOI: No ID Found -
The Journal of Urology Apr 1981Review of the Mayo Clinic tissue registry for the years 1950 to 1979 identified 90 cases of pure, well differentiated eosinophilic granular cell renal tumors. The...
Review of the Mayo Clinic tissue registry for the years 1950 to 1979 identified 90 cases of pure, well differentiated eosinophilic granular cell renal tumors. The clinical, laboratory, pathologic and survival features of these patients were analyzed. Fifty-nine per cent of these tumors were discovered incidentally during an examination for other problems and 91 per cent were confined within the renal capsule, with no evidence of local invasion. Sixty-two patients had grade 1 and 28 had graded 2 tumors. None of the patients with grade 1 tumors developed metastases. Four of the patients with grade 2 tumors died of metastatic disease. Survival curves show no difference in survival between patients with these renal tumors, and an age and sex matched cohort. If the term renal oncocytoma is used to signify a very well differentiated (grade 1) eosinophilic granular cell renal parenchymal tumor then this study demonstrates that renal oncocytomas are non-aggressive tumors with a highly favorable prognosis.
Topics: Adenoma; Adult; Aged; Female; Humans; Kidney Neoplasms; Male; Middle Aged; Neoplasm Metastasis; Prognosis; Retrospective Studies
PubMed: 7218443
DOI: 10.1016/s0022-5347(17)55079-x -
Medicine Aug 2021Nephrogenic adenoma (NA) is a rare benign lesion of the urinary tract, which rarely occurs in the renal pelvis. Only 19 cases have been reported in the literature....
RATIONALE
Nephrogenic adenoma (NA) is a rare benign lesion of the urinary tract, which rarely occurs in the renal pelvis. Only 19 cases have been reported in the literature. However, there is no detailed report on the clinicopathological features of NA of the renal pelvis.
PATIENT CONCERNS
This case report describes a 46-year-old male patient who was admitted to the hospital for one month because of painless gross hematuria with blood clots. He had a history of hyperuricemia and a family history of gastric cancer.
DIAGNOSES
NA of the renal pelvis was diagnosed pathologically and immunohistochemical.
INTERVENTIONS
The patient underwent laparoscopic nephroureterectomy.
OUTCOMES
The patient recovered well after the operation with no discomfort. In addition, we followed up with the patient regularly post-discharge (approximately 20 months). There were no obvious abnormalities in the results of routine urine culture, computed tomography scan of the abdomen, and cystoscopy during the follow-up period, and the symptoms disappeared completely and did not recur.
LESSONS
NA of the renal pelvis is extremely rare in the clinic, which can be easily misdiagnosed and overtreated. However, for pathological diagnosis of this disease, specific immunohistochemical staining for preoperative biopsy was reported to be significant, which should be considered by the urologists and pathologists.
Topics: Adenoma; Humans; Kidney Neoplasms; Kidney Pelvis; Laparoscopy; Male; Middle Aged; Neoplasm Recurrence, Local; Nephroureterectomy
PubMed: 34449477
DOI: 10.1097/MD.0000000000027025 -
Pathology Jan 1982Several authors have recently drawn attention to renal oncocytoma, a neoplasm hitherto rarely recognized. Their reports suggest that renal oncocytomas are not uncommon...
Several authors have recently drawn attention to renal oncocytoma, a neoplasm hitherto rarely recognized. Their reports suggest that renal oncocytomas are not uncommon and that they are benign and possess distinctive gross, microscopical, ultrastructural, and behavioral features. Most examples were discovered on re-examination of neoplasms previously classified as renal adenocarcinoma or adenoma. In a survey of renal neoplasms filed in our Department, we identified 8 cases; these are reported and the literature is reviewed.
Topics: Adenoma; Aged; Female; Humans; Kidney Neoplasms; Male; Microscopy, Electron; Middle Aged
PubMed: 7078991
DOI: 10.3109/00313028209069045 -
Clinical Radiology May 1979In presenting five new cases of renal adenomas the authors describe the general nature of these rare tumours. If the small adenoma corresponding to microscopic forms is...
In presenting five new cases of renal adenomas the authors describe the general nature of these rare tumours. If the small adenoma corresponding to microscopic forms is frequent, the large adenoma is rare and always solitary. Haematuria and pain are the most common signs. The classic criterion of non-malignancy in a solid tumour measuring less than 3 cm has no diagnostic value. From a review of the lieterature on the subject, the authors demonstrate the angio-architecture corresponding to the different types of adenoma: the tubular adenoma which is hypervascularised and well circumscribed; the papillary adenoma, often cortical, hypovascular or avascular with bordering arcade; the alveolar adenoma; the mixed forms. They stress the difficulty of radiological diagnosis and the frequency of transitional forms with cancer. The place of angiography is in the pre-operative diagnostic assessment and in defining localised anomalies in angio-architecture which can guide histological examination in the search for neoplastic foci.
Topics: Adenoma; Cystadenoma; Humans; Kidney Neoplasms; Male; Middle Aged; Radiography; Renal Artery
PubMed: 455910
DOI: 10.1016/s0009-9260(79)80100-2