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JAMA Oncology May 2018
Topics: Counseling; Health Knowledge, Attitudes, Practice; Humans; Neoplasm Grading; Neoplasm Staging; Practice Guidelines as Topic; Randomized Controlled Trials as Topic; Self-Examination; Skin Neoplasms
PubMed: 29558534
DOI: 10.1001/jamaoncol.2018.0469 -
Journal of Cancer Survivorship :... Oct 2021With the continued increase in skin cancer incidence rates, the population of skin cancer survivors continues to grow. Understanding skin cancer survivors' lifestyle...
PURPOSE
With the continued increase in skin cancer incidence rates, the population of skin cancer survivors continues to grow. Understanding skin cancer survivors' lifestyle behaviors, including ultraviolet radiation exposure, is important in reducing skin cancer recurrences and improving health outcomes. The objective of this study is to compare the differences in lifestyle behaviors among skin cancer survivors or individuals who currently have skin cancer versus individuals who have never had a skin cancer diagnosis.
METHODS
To investigate these lifestyle behaviors, we performed a cross-sectional analysis comparing lifestyle behaviors in persons diagnosed with skin cancer and those without a history of skin cancer among US citizens using publicly available data from the 2018 Behavior Risk Factor Surveillance System (BRFSS).
RESULTS
In total, there were 437,436 respondents. No significant difference existed between the two cohorts in sunburn frequency, use of sun protection, or indoor tanning; in fact, males were more likely to be afflicted with sunburns following diagnosis. Skin cancer survivors were less likely to be current smokers and sedentary. Female survivors were more likely to binge and heavily drink alcohol.
CONCLUSION
Our findings highlight important areas for reducing risk factors, which could reduce the recurrence of skin malignancies in skin cancer survivors.
IMPLICATIONS FOR CANCER SURVIVORS
Our study provides insight to lifestyle behaviors among skin cancer survivors. Being aware of these behaviors has the potential to reduce skin cancer recurrence.
Topics: Behavioral Risk Factor Surveillance System; Cross-Sectional Studies; Female; Humans; Life Style; Male; Neoplasm Recurrence, Local; Skin Neoplasms; Sunlight; Sunscreening Agents; Ultraviolet Rays
PubMed: 33230725
DOI: 10.1007/s11764-020-00971-y -
Advances in Medical Sciences 2007Pilomatrixoma is a benign skin neoplasm that arises from hair follicle matrix cells. The skin lesion occurs usually as a solitary tumor and the multifocal types are very...
Pilomatrixoma is a benign skin neoplasm that arises from hair follicle matrix cells. The skin lesion occurs usually as a solitary tumor and the multifocal types are very rare. Skin changes can be described as a firm to hard, non-painful, oval-shaped tumor that is covered by normal skin. It commonly occurs on a scalp, face, neck and rarely back and extremities. Complete surgical excision with the proper margin is the treatment of choice, what guaranteed the radical therapy of pilomatrixoma. In this paper case of 16-years-old male patient with many solid tumors in subcutaneous tissue on both arms will be reported. The first skin lesion appeared on the left arm 6 years ago. Clinically the disturbance was diagnosed as an atheroma, and it was excised. One year after surgical procedure the patient observed the appearance of new nodules on both arms. In the therapy surgical excision was performed with histopathological examination of the tissues. Histopathological test has proved the clinical diagnosis of pilomatrixoma. The case of multifocal pilomatrixoma, which is rarely diagnosed and described in professional literature, will be presented.
Topics: Adolescent; Cicatrix; Diagnosis, Differential; Humans; Immunohistochemistry; Inflammation; Male; Pilomatrixoma; Skin Neoplasms; Treatment Outcome
PubMed: 18217427
DOI: No ID Found -
Cancer Treatment Reviews Aug 2014Skin has the highest incidence and variety of tumors of all organs. Its structure is of great complexity, and every component has the potential to originate a skin... (Review)
Review
Skin has the highest incidence and variety of tumors of all organs. Its structure is of great complexity, and every component has the potential to originate a skin neoplasm (SN). Because of its exposed nature, skin is vulnerable to carcinogenic stimuli such as UV radiation. Various entities can cause SN. Nonmelanotic skin cancers (NMSC) are the most common of all cancers, with over one million cases diagnosed annually in the US. Basal cell carcinoma (BCC) accounts for approximately 80% of all NMSC, most of the remaining 20% being squamous cell carcinoma (SCC). The skin of the head and neck is the most common site for tumors, accounting for more than 80% of all NMSC. BCC, SCC, and malignant melanomas (MM) represent 85-90% of all SN. Merkel cell tumors (MCC), lymphoepithelioma-like carcinomas of the skin (LELCS), dermato-fibro-sarcomas, leiomyosarkomas, and Kaposi-sarcomas are less frequent in the facial skin region and the external ear. Based on data from the German Federal Cancer Registry (2003/2004), 140,000 people in Germany were affected by SN (100,000 BCC, 22,000 SCC, 22,000 MM). This number increases considerably if malignant precursors, such as actinic keratosis, are included. Each year, the frequency of SN diagnosis rises by 3-7%. Among all known malignant tumors, MM exhibits the highest rate of increase in incidence. In the past, SN was primarily diagnosed in people aged 50 years or older. However, recently, the risk for developing SN has shifted, and younger people are also affected. Early diagnosis is significantly correlated with prognosis. Resection of SN creates defects that must be closed with local or microvascular flaps to avoid functional disturbing scar formation and deflection of the nose, eyelids, or lips. All therapeutic strategies for SN, the current standard for adjuvant and systemic treatment, and the management of the increasing number of patients under permanent blood thinner medication are described with regard to the treatment of SN.
Topics: Ear, External; Early Detection of Cancer; Facial Neoplasms; Humans; Melanoma; Skin Diseases; Skin Neoplasms
PubMed: 24814015
DOI: 10.1016/j.ctrv.2014.04.002 -
Dermatologic Therapy Sep 2019Pilomatrixoma, also known as calcifying epithelioma of Malherbe, is a benign skin neoplasm originating from hair follicle matrix cells. Pilomatrixoma is a common skin...
Pilomatrixoma, also known as calcifying epithelioma of Malherbe, is a benign skin neoplasm originating from hair follicle matrix cells. Pilomatrixoma is a common skin neoplasm that is often misdiagnosed as another type of skin condition. The aim of our study is to review 11 years' worth of experience in examining clinical and histopathological presentations, imaging findings, management approaches, and treatment outcomes of pilomatrixoma at a tertiary hospital. A review of the pathology database revealed that 108 extremity pilomatrixomas were excised between 2007 and 2018. Hospital charts, and pathology and orthopedic clinic records, were reviewed for patient data such as age, gender, clinical and histopathological presentations, preoperative diagnosis and imaging results, management approach, recurrence, and treatment outcomes. The main presenting symptom was a hard, subcutaneous, slowly growing mass. The preoperative diagnosis was accurate and consistent with the pathological diagnosis of pilomatrixoma in only 35 cases (32%). The optimal diagnostic tool for pilomatrixoma seems to be ultrasound imaging of superficial tissue, and the optimal first-line treatment might be surgical excision with clear margins. However, pilomatrixoma is a benign tumor, with atypical forms, and there no tumor-specific diagnostic tool is available other than careful histopathological examination.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Dermatologic Surgical Procedures; Female; Follow-Up Studies; Forecasting; Hair Diseases; Humans; Lower Extremity; Magnetic Resonance Imaging; Male; Middle Aged; Pilomatrixoma; Retrospective Studies; Skin; Skin Neoplasms; Ultrasonography; Upper Extremity; Young Adult
PubMed: 31241214
DOI: 10.1111/dth.13004 -
Gan To Kagaku Ryoho. Cancer &... Feb 2010Clinical and histopathological findings of skin metastasis show much variation. When skin metastatic carcinoma is diagnosed by histopathologic evaluation of the involved...
Clinical and histopathological findings of skin metastasis show much variation. When skin metastatic carcinoma is diagnosed by histopathologic evaluation of the involved skin, the treatment must be started as soon as possible after immediate identification of the primary internal organ and the stage of the disease. Furthermore, one must investigate and infer the type of primary tumor from the previous history of internal malignancy, immunohistochemical findings and/or the results of some imaging. When a primary organ is confirmed, consultation with the department specializing in primary tumors is required for close inspection and treatment. When the primary origin is unidentified, detailed discussion is required about the diagnosis and therapeutic examination among the specialized departments including dermatology.
Topics: Combined Modality Therapy; Humans; Neoplasm Staging; Neoplasms; Skin Neoplasms
PubMed: 20154476
DOI: No ID Found -
La Revue Du Praticien Apr 1999Melanoma has the worst pronostic among the cutaneous tumours. Many patients die with this tumour. It is the cancer whose incidence increases the most among all the... (Review)
Review
Melanoma has the worst pronostic among the cutaneous tumours. Many patients die with this tumour. It is the cancer whose incidence increases the most among all the tumours (double every 10 years). The pronostic of melanoma is very bad at metastatic stage. On the contrary, the excision of tumour at an early stage may be associated to a complete remission. So it is important to encourage skin cancer detection for an early treatment of melanoma. Finally, it appears crucial to increase the diffusion of informations about the photoprotection. Indeed, solar exposition probably plays on important role in the increasing incidence fo this skin tumour.
Topics: Humans; Incidence; Melanoma; Neoplasm Staging; Prognosis; Risk Factors; Skin Neoplasms; Ultraviolet Rays
PubMed: 10337195
DOI: No ID Found -
Skin Research and Technology : Official... Aug 2015The characteristic vascular patterns of nonpigmented skin tumors have been established by dermoscopy. Recently, in vivo reflectance confocal microscopy (RCM) has become...
BACKGROUND
The characteristic vascular patterns of nonpigmented skin tumors have been established by dermoscopy. Recently, in vivo reflectance confocal microscopy (RCM) has become an established method for the noninvasive examination of skin tumors.
OBJECTIVES
Determination of the value of RCM on the vascularity of nonpigmented skin tumors.
METHODS
One hundred and twenty two tumoral lesions have been evaluated by RCM in terms of their vascular structures. They were classified in five groups as basal cell carcinoma (BCC), seborrheic keratosis (SK), squamous cell carcinoma (SCC)/keratoacanthoma, actinic keratosis (AK)/Bowen disease and others. Vascular morphologies were investigated as curved linear, straight linear, branching, tubular/canalicular, round and polymorphic vessels in six types.
LIMITATIONS
Relatively, small number of patients with some tumor subgroups is limitation. Larger prospective studies are required before firm conclusions can be drawn.
RESULTS
Excellent compliance was obtained in interobserver analysis. Branching vessels had a high predictive value for basal cell carcinoma (BCC) with RCM (P < 0.001). Also vascular polymorphism was more frequently (69.4%) seen in malignant nonpigmented tumors (P < 0.05) than benign nonpigmented tumors (30.6%). Furthermore, vessels with opposite flows had high predictive value for malignant tumors (P < 0.05) compared with benign tumors.
CONCLUSION
Vascular properties can be evaluated in the diagnosis of nonpigmented tumoral skin lesions via RCM.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Dermoscopy; Female; Humans; Image Enhancement; Male; Microscopy, Confocal; Middle Aged; Neovascularization, Pathologic; Observer Variation; Pigmentation Disorders; Reproducibility of Results; Sensitivity and Specificity; Skin Neoplasms; Young Adult
PubMed: 25345376
DOI: 10.1111/srt.12197 -
Journal of the National Medical... Jun 2002We report 25 cases of skin neoplasm observed among 30 Long Evans rats serving as controls in a psychosocial behavioral study conducted in the Vivarium at Charles R. Drew...
We report 25 cases of skin neoplasm observed among 30 Long Evans rats serving as controls in a psychosocial behavioral study conducted in the Vivarium at Charles R. Drew University, Los Angeles, CA. The animals were 10 weeks old at the beginning of the study. All the skin tumors developed at 18 to 26 months of age and slowly enlarged over a period of 9 months. Multiple nodules occurred in 8 males and 6 females. None of the tumors regressed. The tumors were located around the hind leg and dorso-medial area and measured 1 to 2 cm. Physical examination revealed firm well demarcated dermal masses. Most of the tumor nodules were intradermal, and some had a central ulcerated or keratin-filled core. Microscopic examination performed on some of the tumors showed findings of classic Keratoacanthoma, whereas others showed histologic features suggestive of squamous cell carcinoma. These findings indicate a high rate (83%) of spontaneous skin neoplasms among aging Long Evans rats. To our knowledge, such a high rate of skin neoplasms in aged rodents has not been described in the literature. Furthermore, further studies should be undertaken to confirm these findings and to assess whether these rodents might serve as a model for studying the alterations in the immune system with aging.
Topics: Aging; Animals; Carcinoma, Squamous Cell; Female; Keratoacanthoma; Male; Rats; Rats, Long-Evans; Skin Neoplasms
PubMed: 12078932
DOI: No ID Found -
RN Jul 2000
Review
Topics: Humans; Incidence; Neoplasm Staging; Patient Education as Topic; Physical Examination; Primary Prevention; Risk Factors; Skin Neoplasms; Sunscreening Agents; United States
PubMed: 10983166
DOI: No ID Found