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Experimental Eye Research Jun 1990
Review
Topics: Animals; Humans; Lens, Crystalline; Sorbitol
PubMed: 2197104
DOI: 10.1016/0014-4835(90)90098-f -
Nature Reviews. Gastroenterology &... May 2024
Topics: Humans; Sorbitol; Food Intolerance
PubMed: 38528200
DOI: 10.1038/s41575-024-00921-4 -
ChemSusChem Mar 2022Isosorbide is one of the most interesting cellulosic-derived molecules with great potential to be implemented in wide range of products that shaping our daily life. This... (Review)
Review
Isosorbide is one of the most interesting cellulosic-derived molecules with great potential to be implemented in wide range of products that shaping our daily life. This Review describes the recent developments in the production of isosorbide from sorbitol in batch and continuous-flow systems under hydrothermal conditions using solid acid catalysts. Moreover, the current hurdles and challenges regarding the synthesis of isosorbide from cellulosic biomass in continuous-flow process using solid acid catalysts are summarized, as well as the scaling-up of this process into pilot level, which will lead to an established industrial process with high sustainability metrics.
Topics: Biomass; Catalysis; Dehydration; Humans; Isosorbide; Sorbitol
PubMed: 34931452
DOI: 10.1002/cssc.202102525 -
Nihon Rinsho. Japanese Journal of... Aug 1999
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Nihon Rinsho. Japanese Journal of... Feb 1995
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The Annals of Pharmacotherapy Jan 2000To summarize published data on the comparative efficacy of sorbitol and xylitol for prevention of dental caries. (Comparative Study)
Comparative Study Review
OBJECTIVE
To summarize published data on the comparative efficacy of sorbitol and xylitol for prevention of dental caries.
DATA SOURCES
Published double-blind comparative trials, using sorbitol and xylitol products, identified by MEDLINE (January 1966-December 1998) and International Pharmaceutical Abstracts (January 1970-December 1998) searches.
DATA SYNTHESIS
Clinical trials generally used sorbitol and xylitol gums, which patients chewed three to five times daily for 20-40 months. Xylitol was superior to sorbitol in two longer, secondary dentition trials (30-63% reductions), but not in two primary dentition trials.
CONCLUSIONS
The data suggest that xylitol-containing gums may provide superior efficacy in reducing caries rates in high-risk populations.
Topics: Clinical Trials as Topic; Dental Caries; Humans; Sorbitol; Xylitol
PubMed: 10669192
DOI: 10.1345/aph.19020 -
World Review of Nutrition and Dietetics 1991
Review
Topics: Dental Caries; Dietary Carbohydrates; Fermentation; Humans; Mouth; Sorbitol
PubMed: 2048325
DOI: 10.1159/000419465 -
Cellular Physiology and Biochemistry :... 2000It is well accepted that organic osmolytes, including sorbitol, play a major role in the volume regulation of renal medullary cells. The signal leading to an activation... (Review)
Review
It is well accepted that organic osmolytes, including sorbitol, play a major role in the volume regulation of renal medullary cells. The signal leading to an activation of release channels during RVD is, however, poorly understood. Hypotonicity induced sorbitol efflux was investigated in freshly isolated rat inner medullary collecting duct (IMCD) cells and in rabbit medullary thick ascending limb of Henle's loop (TALH) cells biochemically or using labeled sorbitol. The time course of release was compared with changes in cell volume, measured by confocal microscopy, and alterations in cell calcium (Ca(i)) determined by Fura 2 technology. In IMCD cells sorbitol release, volume decrease and Ca(i) transients show a close temporal correlation. In addition increases in Ca(i) without volume changes stimulate sorbitol efflux. In TALH cells sorbitol release starts after a significant lag time and reaches a maximum when cell volume is already partially restored. The same discrepancy is observed with regard to changes in Ca(i) and sorbitol efflux. These studies suggest that in IMCD cells changes in Ca(i) are the main regulator for the sorbitol permeability of the plasma membrane. The sorbitol channel present in TALH cells seems to operate predominantly independently of Ca(i). Despite this diversity in signal transduction the sorbitol channels in both renal cell types appear, however, not to be stretch-activated.
Topics: Animals; Biological Transport; Kidney Medulla; Sorbitol
PubMed: 11125218
DOI: 10.1159/000016376 -
Lancet (London, England) Aug 1973
Topics: Blood Vessels; Humans; Lens, Crystalline; Neurons; Sorbitol
PubMed: 4124547
DOI: 10.1016/s0140-6736(73)93218-2 -
Lancet (London, England) Jul 1973
Topics: Aging; Animals; Diabetes Mellitus; Diet; Humans; Rats; Sorbitol
PubMed: 4123614
DOI: 10.1016/s0140-6736(73)93315-1