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The Indian Medical Gazette Sep 1942
PubMed: 29012662
DOI: No ID Found -
Veterinary Microbiology Jan 2009Rat bite fever (RBF) is a bacterial zoonosis for which two causal bacterial species have been identified: Streptobacillis moniliformis and Spirillum minus. Haverhill... (Review)
Review
Rat bite fever (RBF) is a bacterial zoonosis for which two causal bacterial species have been identified: Streptobacillis moniliformis and Spirillum minus. Haverhill fever (HF) is a form of S. moniliformis infection believed to develop after ingestion of contaminated food or water. Here the infectious agents, their host species, pathogenicity (virulence factors and host susceptibility), diagnostic methods, therapy, epidemiology, transmission and prevention are described. Special emphasis is given on information from the field of laboratory animal microbiology and suggestions for future research.
Topics: Animals; Humans; Rat-Bite Fever; Rats; Spirillum; Streptobacillus
PubMed: 19008054
DOI: 10.1016/j.vetmic.2008.09.079 -
The Indian Medical Gazette Apr 1936
PubMed: 29013025
DOI: No ID Found -
Rheumatology International Oct 2023Rat bite fever (RBF) is a rare infectious zoonotic disease caused by two bacterial species: the Gram-negative rod Streptobacillus moniliformis and the Gram-negative... (Review)
Review
Rat bite fever (RBF) is a rare infectious zoonotic disease caused by two bacterial species: the Gram-negative rod Streptobacillus moniliformis and the Gram-negative coiled rod Spirillum minus. The association between RBF and skin vasculitis and arthritis has been observed. The aim of this paper was to present a case of rat-bite fever with symptoms of skin vasculitis and arthritis, associated with high titers of ANCA antibodies and anti-endothelial cell antibodies suggestive of primary vasculitis. The patient was successfully treated with antibiotics and non-steroidal anti-inflammatory drugs, leading to significant improvement. Based on the presented case, we discuss the differential diagnosis of the signs and the role of infection in the induction of ANCA antibodies. We reviewed the English language literature for cases of RBF presenting with symptoms of vasculitis and/or antibody presence. A literature review was performed in PubMed and Google using the keywords "rat bite fever" AND "vasculitis", "systemic vasculitis", "ANCA", "antiendothelial antibodies". No cases of rat-bite fever with the presence of ANCA antibodies or AECA antibodies in its course have been described thus far. Rat bite fever is a rare disease with nonspecific symptoms. In its course, general weakness, intermittent fever, leukocytoclastic vasculitis, and arthritis are reported. To our knowledge, this is the first reported case of ANCA positivity associated with RBF.
Topics: Animals; Rats; Rat-Bite Fever; Anti-Bacterial Agents; Arthritis; Vasculitis, Leukocytoclastic, Cutaneous; Anti-Neutrophil Cytoplasmic Antibody-Associated Vasculitis
PubMed: 37450033
DOI: 10.1007/s00296-023-05369-4 -
The Indian Medical Gazette Jan 1941
PubMed: 29013451
DOI: No ID Found -
Antonie Van Leeuwenhoek 1952
Topics: Borrelia; Humans; Penicillins; Spirillum; Streptomycin
PubMed: 14944183
DOI: 10.1007/BF02538613 -
The Indian Medical Gazette Apr 1929
PubMed: 29009625
DOI: No ID Found -
The Indian Medical Gazette Jan 1954
PubMed: 29015583
DOI: No ID Found -
Cureus Jul 2023Rat-bite fever (RBF) is a rare systemic infectious disease caused by , , or . As the name implies, the disease is typically transmitted by a rat bite. RBF usually...
Rat-bite fever (RBF) is a rare systemic infectious disease caused by , , or . As the name implies, the disease is typically transmitted by a rat bite. RBF usually presents as a combination of fever, arthritis, and rash. Definitive diagnosis of RBF may prove difficult, as the responsible bacteria are not easily identified with standard testing. We describe a case of RBF in a 34-year-old female who presented with fever, chills, polyarthralgia, and skin rash following a rat bite. Initial vital signs were remarkable for fever and tachycardia. Physical examination revealed an erythematous vesicular and papular rash involving her extremities, buttocks, and oral mucosa. Blood cultures were negative. A skin biopsy revealed leukocytoclastic vasculitis and was negative for Gram stain. Further analysis using specialized immunohistochemistry and polymerase chain reaction (PCR) identified . A diagnosis of RBF was made, and the patient was successfully treated with a two-week course of doxycycline.
PubMed: 37637554
DOI: 10.7759/cureus.42453