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The Homoeopathic Physician Aug 1895
PubMed: 37136381
DOI: No ID Found -
BMJ (Clinical Research Ed.) May 1999
PubMed: 10346772
DOI: 10.1136/bmj.318.7196.1455a -
California State Journal of Medicine Apr 1904
PubMed: 18733059
DOI: No ID Found -
Nature Reviews. Immunology Sep 2020Innate lymphoid cells (ILCs) are important for tissue homeostasis and for the initiation of immune responses. Based on their transcriptional regulation and cytokine... (Review)
Review
Innate lymphoid cells (ILCs) are important for tissue homeostasis and for the initiation of immune responses. Based on their transcriptional regulation and cytokine profiles, ILCs can be categorized into five subsets with defined phenotypes and functional profiles, but they also have the ability to adapt to local environmental cues by changing these profiles. This plasticity raises the question of the extent to which the cytokine production profiles of ILCs are pre-programmed or are a reflection of the tissue microenvironment. Here, we review recent advances in research on ILCs, with a focus on the plasticity of these cells. We highlight the ability of ILCs to communicate with the surrounding microenvironment and discuss the possible consequences of ILC plasticity for our understanding of the biological roles of these cells. Finally, we discuss how we might use this knowledge of ILC plasticity to develop or improve options for the treatment of inflammatory diseases.
Topics: Animals; Cell Plasticity; Humans; Immunity, Innate; Lymphocyte Subsets
PubMed: 32107466
DOI: 10.1038/s41577-020-0282-9 -
Zootaxa Jan 2022New taxonomic considerations in the spitting spider family Scytodidae Blackwall, 1864 are proposed. Here, the family is considered to include two subfamilies: Scytodinae...
New taxonomic considerations in the spitting spider family Scytodidae Blackwall, 1864 are proposed. Here, the family is considered to include two subfamilies: Scytodinae Blackwall, 1864, comprising the genera Scytodes Latreille, 1804 and Dictis L. Koch, 1872, and Scyloxinae subfam. n., comprising the genera Scyloxes Dunin, 1992 and Stedocys Ono, 1995. Scytodes arwa Rheims, Brescovit van Harten, 2006 is considered a senior synonym of Scytodes makeda Rheims, Brescovit van Harten, 2006 syn. n. and the male of Scytodes kumonga Zamani Marusik, 2020 is described for the first time, with the species being newly recorded from Oman. Observations on the natural history of S. kumonga were made using specimens raised to maturity from egg-sacs produced by females collected in Oman. The monotypic genus Soeuria Saaristo, 1997 is synonymized with Dictis, hence the transfer of its type species, D. soeur (Saaristo, 1997) comb. n. to this genus. Dictis thailandica Dankittipakul Singtripop, 2010 is considered incertae sedis, and Dictis striatipes L. Koch, 1872 is considered a senior synonym of Dictis lugubris Thorell, 1887 syn. n., Scytodes bilqis Rheims, Brescovit van Harten syn. n., Dictis denticulata Dankittipakul Singtripop, 2010 syn. n., Dictis ganeshi Keswani, 2015 syn. n. and D. mumbaiensis Ahmed, Satan, Khalap Mohan, 2015 syn. n., and the species is newly reported from several countries. Scyloxes magna (Bristowe, 1952) comb. n. and Scyloxes zhaoi (Wu Li, 2017) comb. n. are transferred to Scyloxes from Scytodes and Stedocys, respectively.
Topics: Animals; Arachnida; Female; Male; Spiders
PubMed: 35391214
DOI: 10.11646/zootaxa.5092.2.1 -
Seminars in Immunology Nov 2022The family of innate lymphoid cells (ILCs) are composed of five canonical subsets, NK cells, ILC1, ILC2, ILC3 and Lymphoid tissue inducer cells. ILCs have important... (Review)
Review
The family of innate lymphoid cells (ILCs) are composed of five canonical subsets, NK cells, ILC1, ILC2, ILC3 and Lymphoid tissue inducer cells. ILCs have important functions in early stages of immune response towards infectious agents. ILCs are highly plastic enabling rapid modification of their functions dependent on the type of microbe and tissue environment to optimally counter these microbes. Data that still accumulate in a rapid pace indicate that these cells are also involved in immunity against tumor cells. Paradoxically ILC subsets have been shown to have tumor suppressing and tumor promoting activities. In this brief review we provide a snapshot of our current knowledge of characteristics and functions of tumor infiltrating ILC subsets and speculate on how these cells can be harnessed to mediate anti-tumor immunity.
Topics: Humans; Immunity, Innate; Lymphocytes; Killer Cells, Natural; T-Lymphocytes, Helper-Inducer; Neoplasms; Lymphoid Tissue; Lymphocyte Subsets
PubMed: 36306660
DOI: 10.1016/j.smim.2022.101654 -
Contact Dermatitis Nov 2022
Topics: Dermatitis, Allergic Contact; Dermatitis, Irritant; Euphorbia; Humans; Irritants
PubMed: 35895285
DOI: 10.1111/cod.14194 -
The Journal of Family Practice Jul 2001
Review
Topics: Gastroesophageal Reflux; Humans; Infant; Infant Food; Vomiting; Weight Gain
PubMed: 11485703
DOI: No ID Found -
Current Opinion in Immunology Feb 2021Five subsets of ILCs are extensively described, Lymphoid Tissue inducer (LTi) cells, cytotoxic NK cells and non-cytotoxic helper ILC1s, ILC2s and ILC3s. So far, the main... (Review)
Review
Five subsets of ILCs are extensively described, Lymphoid Tissue inducer (LTi) cells, cytotoxic NK cells and non-cytotoxic helper ILC1s, ILC2s and ILC3s. So far, the main focus has been on the potent cytokine production by helper ILCs and their plastic nature that allows them to switch function and phenotype upon environmental changes. Recent advances in the field indicate the presence of cytotoxic helper ILCs that are distinct from conventional NK cells. In humans, these cytotoxic ILCs can develop from conventional helper ILCs whereas in mice this remains to be elucidated. In this review we discuss the identification, development and function of cytotoxic helper ILCs subsets in humans and mice.
Topics: Animals; Humans; Immunity, Innate; Killer Cells, Natural; Lymphocytes
PubMed: 32971468
DOI: 10.1016/j.coi.2020.08.007 -
Indian Journal of Critical Care... Jan 2017In India, eating Chinese food has become very popular. We hereby report a case who presented with angioneurotic edema of the uvula and the surrounding structures, after...
In India, eating Chinese food has become very popular. We hereby report a case who presented with angioneurotic edema of the uvula and the surrounding structures, after eating Chinese food, which resulted in severe difficulty in swallowing saliva and inability to speak.
PubMed: 28197052
DOI: 10.4103/0972-5229.198327