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Anticancer Research Apr 2022There are carcinogenic effects of sun exposure that increase the risk for skin cancer, especially for fair-skinned individuals. Therefore, there are recommendations to... (Review)
Review
There are carcinogenic effects of sun exposure that increase the risk for skin cancer, especially for fair-skinned individuals. Therefore, there are recommendations to avoid sun exposure and to apply sun blockers. A more nuanced and balanced message for sun safety guidelines is now advocated. Despite an increased risk of death due to skin cancer, fair skinned women seem to have an overall survival advantage. In addition, an inverse association between sun exposure and hypertension, thromboembolism, and type 2 diabetes mellitus has been shown. Furthermore, low sun exposure habits result in increased risk of cardiovascular disease (CVD), and non-CVD/non-cancer mortality among women. There are also data supporting that the prognosis of cancer is improved with increasing levels of vitamin D/sun exposure. In this narrative review we will provide a brief update of hazards and benefits of sun exposure focused on an updated, balanced, and evidence-based view.
Topics: Cardiovascular Diseases; Diabetes Mellitus, Type 2; Female; Humans; Skin Neoplasms; Sunlight; Vitamin D
PubMed: 35346986
DOI: 10.21873/anticanres.15644 -
International Journal of Environmental... Jul 2020This article aims to alert the medical community and public health authorities to accumulating evidence on health benefits from sun exposure, which suggests that... (Review)
Review
This article aims to alert the medical community and public health authorities to accumulating evidence on health benefits from sun exposure, which suggests that insufficient sun exposure is a significant public health problem. Studies in the past decade indicate that insufficient sun exposure may be responsible for 340,000 deaths in the United States and 480,000 deaths in Europe per year, and an increased incidence of breast cancer, colorectal cancer, hypertension, cardiovascular disease, metabolic syndrome, multiple sclerosis, Alzheimer's disease, autism, asthma, type 1 diabetes and myopia. Vitamin D has long been considered the principal mediator of beneficial effects of sun exposure. However, oral vitamin D supplementation has not been convincingly shown to prevent the above conditions; thus, serum 25(OH)D as an indicator of vitamin D status may be a proxy for and not a mediator of beneficial effects of sun exposure. New candidate mechanisms include the release of nitric oxide from the skin and direct effects of ultraviolet radiation (UVR) on peripheral blood cells. Collectively, this evidence indicates it would be wise for people living outside the tropics to ensure they expose their skin sufficiently to the sun. To minimize the harms of excessive sun exposure, great care must be taken to avoid sunburn, and sun exposure during high ambient UVR seasons should be obtained incrementally at not more than 5-30 min a day (depending on skin type and UV index), in season-appropriate clothing and with eyes closed or protected by sunglasses that filter UVR.
Topics: Europe; Humans; Public Health; Sunburn; Sunlight; Ultraviolet Rays; Vitamin D; Vitamin D Deficiency
PubMed: 32668607
DOI: 10.3390/ijerph17145014 -
Current Problems in Dermatology 2021Black skin, compared with white skin, is generally assumed to be more resistant to the consequences of sun exposure due to its epidermal melanin content. However, recent... (Review)
Review
Black skin, compared with white skin, is generally assumed to be more resistant to the consequences of sun exposure due to its epidermal melanin content. However, recent scientific evidence shows that black skin is not completely impervious to sunlight. Both clinical and -experimental data have reported sun-induced effects on black skin. Black skin can warm, burn and peel when -exposed to the sun. Exposure to the sun can also cause hyperpigmentation and photoageing manifestations. The current misconceptions expressed by most black individuals about their resistance to sun-induced effects prevent their engagement in sun safe behaviours. Therefore, the demystification of the harmful effects of the sun needs to be supported by more research studies showing the effectiveness of sun protection strategies for the black population.
Topics: Black People; Health Behavior; Health Knowledge, Attitudes, Practice; Humans; Skin; Skin Neoplasms; Skin Pigmentation; Sunlight
PubMed: 34698032
DOI: 10.1159/000517594 -
Public Health Research & Practice Mar 2022Exposure to ultraviolet (UV) radiation from the sun has both risks, including skin cancer and premalignant lesions, skin aging and cataracts, and benefits, including the... (Review)
Review
IMPORTANCE
Exposure to ultraviolet (UV) radiation from the sun has both risks, including skin cancer and premalignant lesions, skin aging and cataracts, and benefits, including the production of vitamin D. Health policies guide informed decision making about balancing these risks and benefits. However variability in advice given by different agencies (e.g. government, health organisations, consumer organisations) may lead to confusion among the general public, resulting in suboptimal health-related behaviours by consumers.
OBJECTIVE
To review and assess the consistency of recommendations in relevant guidance documents in Australia and New Zealand regarding the risks and benefits of sun exposure. Study type and methods: A rapid desktop review of publicly available sun exposure guidance documents from government and nongovernment websites was undertaken between February and April 2021. Four major themes and their subthemes were extracted from documents: sun protection; balance between risks and benefits of sun exposure; non-vitamin D benefits of sun exposure; and sun exposure and vitamin D production. We then undertook a more detailed analysis of recommendations regarding sun exposure to maintain sufficient vitamin D status.
RESULTS
Nineteen documents met the inclusion criteria (13 Australian, five New Zealand, and one joint Australian and New Zealand document). Most documents provided extensive advice about sun protection and sun exposure and vitamin D production and their respective subthemes, while only 2/19 documents provided advice regarding the non-vitamin D benefits of sun exposure (benefits for melatonin production and reduction of sleep disorders). Documents varied widely in their recommendations in relation to sun exposure required for vitamin D production. For example, while three documents stated that sun exposure is required on most days of the week for adequate vitamin D production, two stated that sun exposure is required daily. One document advised that people with darker skin require three to six times more sun exposure than those with lighter skin, while another advised two to three times more sun exposure is required.
CONCLUSION
Current guidance documents show great variation in the advice for sun exposure and vitamin D production, and little advice is being provided on non-vitamin D health benefits. Extensive variations in the advice provided could be confusing for consumers and result in unhealthy behavioural action. Based on this evidence, better and more consistent guidance and advice about the risk and benefits of sun exposure is required.
Topics: Australia; Humans; New Zealand; Sunlight; Ultraviolet Rays; Vitamin D
PubMed: 35290996
DOI: 10.17061/phrp3212202 -
The Indian Journal of Medical Research Mar 2021Adopting sun exposure as a low-cost sustainable strategy in tropical countries needs critical analysis for its feasibility and inclusion in national policy. This review... (Review)
Review
Adopting sun exposure as a low-cost sustainable strategy in tropical countries needs critical analysis for its feasibility and inclusion in national policy. This review explores the opportunities and challenges associated with sun exposure in tropical countries and discusses potential strategies that may be adopted for promoting sun exposure. For this, two strands of evidence were reviewed; trials on sun exposure, analysed for risk of bias and, the environmental factors that influence acquisition of vitamin D from sun exposure in the context of on-going ecological and nutritional transition. Compilation of data from available databases in terms of deficiency, per cent rural population, status of fortification, air pollution, ultraviolet index, skin reflectance and skin cancer prevalence were done. In the context of environmental and lifestyle-related challenges, opportunities go hand-in-hand in terms of built environment, variability in air pollution and personal factors such as skin pigmentation, precursor availability and general nutritional status. Contextual policy decisions should consider urban and rural development planning, control of air pollution, targeted guidelines for indigenous and immigrant population and use of space technology in educating general population for balanced sun exposure as essential components for a sustainable strategy. Important opportunities exist for tropical countries to develop sun exposure as a strategy for acquiring vitamin D and these need to be explored.
Topics: Developing Countries; Humans; Life Style; Sunlight; Vitamin D; Vitamin D Deficiency
PubMed: 34854426
DOI: 10.4103/ijmr.IJMR_1244_18 -
Photochemical & Photobiological... Mar 2017We aimed to conduct a narrative review of the rapid advances in knowledge regarding sun exposure and all-cause mortality. Data support the hypothesis that sun exposure... (Review)
Review
We aimed to conduct a narrative review of the rapid advances in knowledge regarding sun exposure and all-cause mortality. Data support the hypothesis that sun exposure avoidance is a major risk factor for all-cause mortality in adjusted analysis (age, income, education, marital status, smoking, and comorbidity). This was caused by an increased risk of death due to cardiovascular disease (CVD) and noncancer/non-CVD. However, the increased life span among those with high sun exposure naturally results in an increased prevalence of cancer death. In addition, sun exposure increases the incidence, but is related to better prognosis of skin cancer. The new findings indicate that there is a need for modification of guidelines regarding sun exposure. They may also add to our knowledge regarding the increasing incidence of diabetes mellitus and increased mortality among non-Caucasians in western countries. According to the present knowledge, in a low solar intensity region we should aim for sound and safe sun exposure habits, especially for those at increased risk of CVD or noncancer/non-CVD.
Topics: Cardiovascular Diseases; Cause of Death; Humans; Risk Factors; Skin Neoplasms; Sunbathing; Sunlight
PubMed: 28074966
DOI: 10.1039/c6pp00316h -
Der Hautarzt; Zeitschrift Fur... Jan 2021Skin aging results from the interaction of genetic and nongenetic so-called exposomal, factors. Among the exposomal factors, chronic, life-long exposure to sunlight is... (Review)
Review
Skin aging results from the interaction of genetic and nongenetic so-called exposomal, factors. Among the exposomal factors, chronic, life-long exposure to sunlight is of eminent importance for the development of skin aging characteristics. Importantly, photoaging of human skin is not only caused by ultraviolet (UV) B and A radiation, but is also the consequence of exposure to wavelengths beyond the UV spectrum. These include visible, i.e. blue light (400-440 nm) as well as the short part of infrared radiation, i.e. IRA (760-1200 nm). Here we summarize the scientific evidence supporting these conclusions and emphasize the resulting consequences for daily photoprotection of human skin. We also explain the clinical significance of the concept that is offered by the skin aging exposome, which e.g. takes into account the fact that sunlight interacts with other exposomal factors and that this interaction is important for photoaging of the skin.
Topics: Humans; Skin; Skin Aging; Sunlight; Sunscreening Agents; Ultraviolet Rays
PubMed: 33346860
DOI: 10.1007/s00105-020-04747-4 -
Military Medicine Nov 2021Occupational exposure to ultraviolet radiation is a critical concern for those serving in the U.S. Military. Work and mission requirements predispose members to...
INTRODUCTION
Occupational exposure to ultraviolet radiation is a critical concern for those serving in the U.S. Military. Work and mission requirements predispose members to significant sun exposure, while sun-protective behavior often comes second to mission accomplishment. Prior research implicated institutional practices and constraints as preventing the routine use of sun protection modalities, but no large-scale studies have assessed service members' perceptions regarding sun protection modalities available to them in their work environment or their daily sun protection practices.
METHODS
The study employed a cross-sectional survey distributed to active duty (AD) U.S. Navy service members assigned to 1 of 19 aircraft squadrons based in Southern California and deployed on missions across the Pacific theater of operations. The intent was to evaluate rates of sunburn, sun-protective practices, and perceptions regarding sun exposure and prevention practices in their workplace. The study and survey tool received approval from the Naval Medical Center San Diego Institutional Review Board. Statistical analysis of survey answers was performed to assess for trends in response rates overall and response rates within sociodemographic groups. Pearson's chi-squared tests were utilized to assess for significance where appropriate. P-values <.05 were used to determine statistically significant trends in response rates.
RESULTS
One thousand surveys were distributed, of which 896 surveys were completed. The response rate was 89.6%. Eight hundred and eighty-eight surveys were included in the analysis. The surveyed population was consistent with the demographics of the U.S. Navy as a whole. 55.1% of survey respondents reported sunburn within the past year, higher than the rate reported in a previously surveyed civilian population. Reports of sunburn within the past year were not significantly different in regard to gender (P = .88), age (P = .53), and years of AD (P = .48). Increasing rank did show a significant correlation with reports of sunburn (P = .0) (Table S1). 62.2% of those surveyed reported frequent/routine use of some form of sun protection. This was lower than the rate reported in a previously surveyed civilian population. A large majority of service members surveyed (75.9%) reported using sunscreen with a sun protection factor >15.29.1% of survey respondents reported working in direct sunlight always/almost always. This was lower than the rates reported in a previously surveyed U.S. Air Force population of aviation maintainers. Low rates of respondents reported frequent reminders to use sun protection (18.9%), and fewer reported the routine or frequent use of sunscreen while at work (12.3%). A higher percentage reported regular use of sunscreen during outdoor leisure activities (36.5%), suggesting a barrier to use in the workplace.
CONCLUSIONS
U.S. Military personnel report higher rates of sunburn and lower rates of routine use of sun protection practices compared to a previously surveyed civilian population. The overall rates of sun protection use while in the work setting are low both overall and compared to reports of routine use during outdoor leisure activities. Reported rates of reminders to use sunscreen are low, suggesting that increased education regarding the risk of excessive sun exposure and tools for effective sun protection are still needed.
Topics: Aviation; Cross-Sectional Studies; Health Behavior; Health Knowledge, Attitudes, Practice; Humans; Military Personnel; Skin Neoplasms; Sunlight; Sunscreening Agents; Ultraviolet Rays
PubMed: 33748855
DOI: 10.1093/milmed/usab099 -
Journal of Neurology, Neurosurgery, and... Apr 2016Adult-onset isolated focal dystonia may present with various phenotypes including blepharospasm and cervical dystonia. Although inherited in an autosomal dominant manner... (Meta-Analysis)
Meta-Analysis Review
BACKGROUND
Adult-onset isolated focal dystonia may present with various phenotypes including blepharospasm and cervical dystonia. Although inherited in an autosomal dominant manner with a markedly reduced penetrance, environmental factors are considered important in disease penetrance and expression. We observed a marked variation by latitude in the reports of the frequency of patients with blepharospasm relative to those with cervical dystonia; we hypothesised that sun exposure is an environmental risk factor for the development of blepharospasm in genetically susceptible individuals.
METHODS
From published clinic cohorts and epidemiological reports, the ratio of the number of cases of blepharospasm to cervical dystonia (phenotype case ratio) at each study site was analysed with regard to latitude and measures of annual insolation. Meta-regression analyses of the phenotype case ratio to these environmental factors were performed.
RESULTS
The phenotype case ratio in 15 eligible study sites over 41° of latitude demonstrated a statistically significant inverse association with latitude (p=0.0004, R(2)=53.5%). There were significant positive associations between the phenotype case ratio and quarter-one (January-March) insolation (p=0.0005, R(2)=53%) and average annual insolation (p=0.003, R(2)=40%).
CONCLUSION
The increase in the blepharospasm: cervical dystonia case ratio with decreasing latitude and increasing insolation suggests that sunlight exposure is an environmental risk factor for the development of blepharospasm (rather than cervical dystonia) in individuals genetically susceptible to adult-onset dystonia.
Topics: Blepharospasm; Environment; Genetic Predisposition to Disease; Geography; Humans; Sunlight
PubMed: 25904812
DOI: 10.1136/jnnp-2014-310266 -
Current Oncology (Toronto, Ont.) Feb 2023Sun exposure carries both harms and benefits. Exposing the skin to the sun is the main modifiable cause of skin cancers, which exert a considerable health and economic...
Sun exposure carries both harms and benefits. Exposing the skin to the sun is the main modifiable cause of skin cancers, which exert a considerable health and economic burden in Australia. The most well-established benefit of exposure to ultraviolet (UV) radiation is vitamin D production. Australia has the highest incidence of skin cancer in the world but, despite the high ambient UV radiation, approximately one quarter of the population is estimated to be vitamin D deficient. Balancing the risks and benefits is challenging and requires effective communication. We sought to provide a snapshot of public knowledge and attitudes regarding sun exposure and vitamin D and to examine the associations between these factors and sun protective behaviors. In 2020 we administered an online survey; 4824 participants with self-reported fair or medium skin color were included in this analysis. Only 25% and 34% of participants were able to identify the amount of time outdoors needed to maintain adequate vitamin D status in summer and winter, respectively and 25% were concerned that sunscreen use inhibits vitamin D synthesis. This lack of knowledge was associated with suboptimal sun protection practices. Public education is warranted to prevent over-exposure, while supporting natural vitamin D production.
Topics: Humans; Vitamin D; Sunlight; Vitamin D Deficiency; Ultraviolet Rays; Surveys and Questionnaires; Skin Neoplasms
PubMed: 36826149
DOI: 10.3390/curroncol30020188