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CMAJ : Canadian Medical Association... Sep 2003Recurrent episodes of spontaneously resolving hyperthyroidism may be caused by release of preformed hormone from the thyroid gland after it has been damaged by...
Recurrent episodes of spontaneously resolving hyperthyroidism may be caused by release of preformed hormone from the thyroid gland after it has been damaged by inflammation (recurrent silent thyroiditis) or by exogenous administration of thyroid hormone, which might be intentional or surreptitious (thyrotoxicosis factitia). Community-wide outbreaks of "hamburger thyrotoxicosis" resulting from inadvertent consumption of beef contaminated with bovine thyroid gland have been previously reported. Here we describe a single patient who experienced recurrent episodes of this phenomenon over an 11-year period and present an approach to systematically evaluating patients with recurrent hyperthyroidism.
Topics: Animals; Cattle; Diagnosis, Differential; Female; Food Contamination; Humans; Meat; Middle Aged; Recurrence; Thyrotoxicosis
PubMed: 12952802
DOI: No ID Found -
Lippincott's Primary Care Practice 1997Thyrotoxicosis is a common endocrine problem encountered in the primary care setting. It can exist in the presence or absence of thyroid disease and is associated with a... (Review)
Review
Thyrotoxicosis is a common endocrine problem encountered in the primary care setting. It can exist in the presence or absence of thyroid disease and is associated with a wide range of causes, including primary hyperthyroidism, thyroid inflammation, and ingestion of exogenous thyroid hormone preparations. presenting complaints and clinical manifestations of this disorder can vary greatly, creating a challenge for the primary care provider. Recognition of clinical signs and symptoms and selection of appropriate laboratory studies can establish the diagnosis promptly. Once the diagnosis is identified, various effective and appropriate treatment options are available. It is important to distinguish between those problems that require subspecialty referral and those that can be treated by primary care providers. Many of the syndromes associated with thyrotoxicosis can be managed in the primary care setting. Interventions include patient counselling, patient education, judicious use of appropriate medications, and careful follow-up.
Topics: Aftercare; Diagnosis, Differential; Humans; Primary Health Care; Referral and Consultation; Thyrotoxicosis
PubMed: 9384137
DOI: No ID Found -
The Australian and New Zealand Journal... Mar 2000
Review
Topics: Amiodarone; Anesthesia; Anti-Arrhythmia Agents; Humans; Thyroidectomy; Thyrotoxicosis
PubMed: 10765894
DOI: 10.1046/j.1440-1622.2000.01816.x -
West African Journal of Medicine 2005The majority of patients with thyrotoxicosis are readily diagnosed clinically. It must be accepted however that not every patient presents with the characteristic... (Review)
Review
BACKGROUND
The majority of patients with thyrotoxicosis are readily diagnosed clinically. It must be accepted however that not every patient presents with the characteristic picture. Thyrotoxicosis occasionally presents in an unknown or atypical fashion in which the diagnosis may not be obvious.
CASE REPORT
A 45-year-old woman presented with choreoathetoid movements of the right upper limb, persistent vomiting and generalized body weakness. Over the next few weeks, the clinical picture slowly evolved to give the characteristic symptoms and signs of thyrotoxicosis, which were not evident at presentation. Thyroid function tests revealed elevated serum thyroxine and triiodothyronine as well as low thyroid stimulating hormone concentrations, confirming the diagnosis of thyrotoxicosis.
CONCLUSION
This case illustrates unusual initial presenting features of thyrotoxicosis, which long preceded the development of the characteristic and more common manifestations. This led to a delay in the diagnosis. Awareness of these atypical presentations will further assist the physician to make a timely and cost effective diagnosis of this condition.
Topics: Diagnosis, Differential; Dyskinesias; Female; Headache; Humans; Metoclopramide; Middle Aged; Muscle Weakness; Thyrotoxicosis; Upper Extremity; Vomiting
PubMed: 16276712
DOI: 10.4314/wajm.v24i3.28215 -
Nihon Rinsho. Japanese Journal of... May 2006
Review
Topics: Amiodarone; Anti-Arrhythmia Agents; Diagnosis, Differential; Humans; Thyrotoxicosis
PubMed: 16776147
DOI: No ID Found -
Nihon Rinsho. Japanese Journal of... May 2006
Review
Topics: Antithyroid Agents; Autoantibodies; Diagnosis, Differential; Graves Disease; Humans; Immunoglobulins, Thyroid-Stimulating; Methimazole; Receptors, Thyrotropin; Thyroid Function Tests; Thyroiditis, Subacute; Thyrotoxicosis
PubMed: 16776140
DOI: No ID Found -
Acta Chirurgica Belgica 2001Thyrotoxicosis is the clinical syndrome that results when tissues are exposed to high levels of circulating thyroid hormones. In most instances, thyrotoxicosis is due to... (Review)
Review
Thyrotoxicosis is the clinical syndrome that results when tissues are exposed to high levels of circulating thyroid hormones. In most instances, thyrotoxicosis is due to hyperthyroidism, a term reserved for disorders characterized by overproduction of thyroid hormones by the thyroid gland. Nevertheless, thyrotoxicosis may also result from a variety of conditions other than thyroid hyperfunction. The present report focuses on the etiologies, pathophysiology and treatment of iatrogenic thyrotoxicosis. Iatrogenic thyrotoxicosis may be caused by 1) subacute thyroiditis (a result of lymphocytic infiltration, cellular injury, trauma or radiation) with release of preformed hormones into circulation, 2) excessive ingestion of thyroid hormones ("thyrotoxicosis factitia"), 3) iodine-induced hyperthyroidism (radiological contrast agents, topical antiseptics or other medications). Among these causes of iatrogenic thyrotoxicosis, that induced by the iodine overload and cytotoxicity associated with amiodarone represents a significant challenge. Successful management of amiodarone-induced thyrotoxicosis requires close cooperation between endocrinologists and endocrine surgeons. Surgical treatment may have a leading yet often underestimated role in view of the potential life-threatening severity of this disease, whereas others kinds of iatrogenic thyrotoxicosis are usually treated conservatively.
Topics: Amiodarone; Anti-Arrhythmia Agents; Causality; Humans; Iodine; Patient Selection; Thyrotoxicosis
PubMed: 11868500
DOI: No ID Found -
Southern Medical Journal Nov 1988Clinicians should be on the alert for the possibility of underlying thyrotoxicosis in patients having an affective disturbance. An initial detailed medical history and...
Clinicians should be on the alert for the possibility of underlying thyrotoxicosis in patients having an affective disturbance. An initial detailed medical history and complete physical examination is essential even in severely agitated, threatening patients. The danger of inappropriate diagnosis and treatment of these patients requires a high index of suspicion in detecting the underlying thyroid disturbance.
Topics: Adult; Bipolar Disorder; Commitment of Mentally Ill; Humans; Iodine Radioisotopes; Male; Propranolol; Propylthiouracil; Thyrotoxicosis
PubMed: 3187640
DOI: 10.1097/00007611-198811000-00032 -
Cleveland Clinic Journal of Medicine Jul 2023
Topics: Humans; Amiodarone; Anti-Arrhythmia Agents; Thyrotoxicosis
PubMed: 37400151
DOI: 10.3949/ccjm.90a.22084 -
Southern Medical Journal May 2002We report the case of an 87-year-old woman with coma who was found to be in thyrotoxic crisis. The patient had a recent history of decreased mentation and apathy, and... (Review)
Review
We report the case of an 87-year-old woman with coma who was found to be in thyrotoxic crisis. The patient had a recent history of decreased mentation and apathy, and laboratory findings were found to be consistent with hyperthyroidism. After a stormy course, the clinical condition recovered to baseline, with return of laboratory values to normal following antithyroid therapy. We provide the details of this rarely documented presentation of apathetic hyperthyroidism with thyroid storm and coma and review the characteristics of similar cases in the literature.
Topics: Affective Symptoms; Aged; Aged, 80 and over; Coma; Diagnosis, Differential; Female; Humans; Thyroid Crisis; Thyrotoxicosis
PubMed: 12005017
DOI: No ID Found