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Clinical Radiology Jun 2005Magnetic resonance imaging (MRI) has become an important part of the assessment of suspected vaginal pathology. This pictorial review demonstrates the MRI features and... (Review)
Review
Magnetic resonance imaging (MRI) has become an important part of the assessment of suspected vaginal pathology. This pictorial review demonstrates the MRI features and some of the histopathological findings of a variety of vaginal conditions. These may be congenital (total vaginal agenesis, partial vaginal agenesis, longitudinal vaginal septum, transverse vaginal septum), benign (Bartholin's cyst, diffuse vaginal inflammation, invasive endometriosis, ureterovaginal fistula, post-surgical appearances with the formation of a neovagina and adhesions) or malignant, usually due to extension or recurrence from another pelvic malignancy. In this paper, examples of the above are described and illustrated together with examples of the much rarer primary vaginal malignancies.
Topics: Adenocarcinoma; Adolescent; Adult; Aged; Carcinoma, Squamous Cell; Female; Humans; Magnetic Resonance Imaging; Middle Aged; Sensitivity and Specificity; Vagina; Vaginal Diseases; Vaginal Neoplasms
PubMed: 16038691
DOI: 10.1016/j.crad.2005.02.010 -
British Medical Journal Jan 1965
Topics: Biopsy; Carcinoma in Situ; Carcinoma, Squamous Cell; Cell Division; Chromosome Aberrations; Cytodiagnosis; DNA; DNA, Neoplasm; Epithelium; Female; Humans; Neoplasms; Pathology; Uterine Cervical Neoplasms; Vagina
PubMed: 14222592
DOI: 10.1136/bmj.1.5428.154 -
International Urogynecology Journal Jan 2017Neovaginal prolapse (NP) is a rare event as few cases have been reported in the literature. Its management is complex and depends on the initial pathology, the... (Review)
Review
INTRODUCTION AND HYPOTHESIS
Neovaginal prolapse (NP) is a rare event as few cases have been reported in the literature. Its management is complex and depends on the initial pathology, the vaginoplasty technique and the patient's history. We present a review the literature on this rare event.
METHODS
We describe the case of a 72-year-old woman who presented with NP 1 year after pelvic exenteration and radiotherapy for recurrent cervical carcinoma associated with vaginal reconstruction by shaped-tube omentoplasty. She had undergone two previous surgical procedures (posterior sacrospinous ligament suspension and partial colpocleisis), but NP recurred each time within a few months. We performed an anterior approach to the sacrospinous ligament and inserted a mesh under the anterior wall of the neovagina, with the two mesh arms driven through the sacrospinous ligament in a tension-free manner (Uphold Lite® system). The MEDLINE, Cochrane Library, ClinicalTrials and OpenGrey databases were systematically searched for literature on the management of NP following bowel vaginoplasty, mechanical dilatation, graciloplasty, omentoplasty, rectus abdominis myocutaneous flap and the Davydov procedure.
RESULTS
The postoperative course in the patient whose case is described was uneventful and after 1 year of follow-up, the anatomical results and patient satisfaction were good. The systematic search of the databases revealed several studies on the treatment of NP using abdominal and vaginal approaches, and these are reviewed.
CONCLUSIONS
Overall, sacrocolpopexy would appear to be a good option for the treatment of prolapse after bowel vaginoplasty, but too few cases have been reported to establish this technique as the standard management of NP.
Topics: Aged; Carcinoma; Female; Humans; Neoplasm Recurrence, Local; Pelvic Exenteration; Postoperative Complications; Plastic Surgery Procedures; Sacrum; Surgical Mesh; Treatment Outcome; Uterine Cervical Neoplasms; Uterine Prolapse; Vagina
PubMed: 27038991
DOI: 10.1007/s00192-016-3009-5 -
Journal of Surgical Oncology 1980A case is presented of transitional-cell cloacogenic carcinoma -- a rare variant of anal canal malignancy that occurred in a 58-year-old woman. The characteristics of...
A case is presented of transitional-cell cloacogenic carcinoma -- a rare variant of anal canal malignancy that occurred in a 58-year-old woman. The characteristics of this tumor are discussed, and her prognosis after abdominoperineal resection and posterior colpectomy seems good.
Topics: Anus Neoplasms; Carcinoma, Transitional Cell; Female; Humans; Middle Aged; Prognosis; Vagina
PubMed: 7392643
DOI: 10.1002/jso.2930140304 -
The American Journal of Roentgenology... Jul 1950
Topics: Carcinoma; Female; Humans; Neoplasms; Radium; Vagina
PubMed: 15425695
DOI: No ID Found -
International Journal of Gynecological... May 2019The incidence of cervical adenocarcinoma, both absolute and relative to squamous cell carcinoma, is increasing. Most cervical adenocarcinomas are human papillomavirus...
The incidence of cervical adenocarcinoma, both absolute and relative to squamous cell carcinoma, is increasing. Most cervical adenocarcinomas are human papillomavirus associated, although non-human papillomavirus-associated neoplasms exist; the latter include gastric-type adenocarcinoma (GAS) and clear cell carcinoma (CCC). Histologically, these 2 tumors may superficially resemble one other and although morphologic evaluation usually permits a correct diagnosis, immunohistochemistry may be required to resolve diagnostic uncertainty, especially in a small biopsy specimen. Markers of CCC include hepatocyte nuclear factor 1 beta (HNF1β) and Napsin A. In order to explore the utility of these markers in distinguishing between GAS and CCC, we stained 24 cases of GAS (19 cervical, 5 vaginal), 3 of cervical gastric-type adenocarcinoma in situ (gAIS) and 14 CCCs (13 cervical, 1 vaginal) with these antibodies. We found HNF1β expression in 21 of 23 cases of GAS (91.3%; there was no material available for staining in 1 case), 3/3 cases of gAIS (100%) and 10 of 14 (71.4%) CCCs. Napsin A was expressed in 4 of 24 (16.7%) cases of GAS, 0 of 3 (0%) gAIS, and 11 of 14 (78.6%) CCC. On the basis of these findings, Napsin A is of value in resolving diagnostic confusion between GAS and CCC, whereas HNF1β lacks specificity and its use in this setting is discouraged.
Topics: Adenocarcinoma, Clear Cell; Aspartic Acid Endopeptidases; Biomarkers, Tumor; Cervix Uteri; Diagnosis, Differential; Female; Hepatocyte Nuclear Factor 1-beta; Humans; Immunohistochemistry; Sensitivity and Specificity; Stomach Neoplasms; Uterine Cervical Neoplasms; Vagina; Vaginal Neoplasms
PubMed: 29901522
DOI: 10.1097/PGP.0000000000000529 -
Radiology Oct 1988The potential of magnetic resonance (MR) imaging in the detection of vaginal tumors and the assessment of their extent was evaluated retrospectively in 87 patients in...
The potential of magnetic resonance (MR) imaging in the detection of vaginal tumors and the assessment of their extent was evaluated retrospectively in 87 patients in whom primary, metastatic, or recurrent vaginal cancer was clinically suspected. MR findings were compared with the results of surgery and/or biopsy. Results of histopathologic study verified a normal vagina in 51 patients, benign cysts in two, primary tumor in four, metastatic cancer in 22, and recurrent tumor in eight. MR imaging demonstrated the two benign cysts, correctly depicting their size and location, and demonstrated and enabled correct staging of the four primary tumors. MR accuracy for demonstrating metastatic cancer was 92%, sensitivity was 95%, and specificity was 90%. Tumor extension to the vagina was reliably excluded (negative predictive value = 97%), but false-positive interpretations occurred (positive predictive value = 84%) primarily because inflammation (n = 2) and congestion (n = 2) could not be distinguished from tumor invasion. An additional role of MR imaging was the ability to differentiate tumor from fibrotic tissue in patients with suspected recurrent vaginal carcinoma. The overall accuracy of MR imaging for recurrent vaginal cancer was 82% (14 of 17).
Topics: Adult; Carcinoma; False Negative Reactions; False Positive Reactions; Female; Humans; Magnetic Resonance Imaging; Vagina; Vaginal Neoplasms
PubMed: 3420257
DOI: 10.1148/radiology.169.1.3420257 -
Cancer 1955
Topics: Carcinoma; Cervix Uteri; Female; Humans; Neoplasms; Radium; Vagina
PubMed: 13261059
DOI: 10.1002/1097-0142(1955)8:5<1016::aid-cncr2820080526>3.0.co;2-n -
American Journal of Veterinary Research Nov 2022To investigate typical computed tomography (CT) features for the differentiation of vaginal from the uterine origin in dogs.
OBJECTIVE
To investigate typical computed tomography (CT) features for the differentiation of vaginal from the uterine origin in dogs.
ANIMALS
7 healthy Beagles in the prospective study and 5 bitches in the retrospective study.
PROCEDURES
In the prospective study, dual-phase CT images were obtained from sexually intact female Beagles (n = 7) during anestrus and estrus. On the CT images, the vagina and uterine horns, body, and cervix were assessed for diameter, attenuation, and contrast enhancement pattern. In the retrospective study, CT features of large vaginal lesions (leiomyoma, leiomyosarcoma, adenocarcinoma, hematocolpos, and Gartner's duct cyst) were assessed in 5 bitches.
RESULTS
In normal bitches, the cervix was thicker with strong central enhancement compared to the uterus and vagina. The uterine artery, which enters the mesometrium at the level of the cervix, was clearly visualized and assisted in identifying the cervix. In bitches with large vaginal masses, uterine arteries were displaced by the lesions and could not be used to locate the cervix. In 4/5 dogs with vaginal masses, identification of the cervix allowed the determination of the organ of origin. In 1 dog with adenocarcinoma, CT vaginography was additionally required for determining the origin of mass.
CLINICAL RELEVANCE
Results from this study indicate that the cervix, recognized in CT as focal thickening of the uterus with central enhancement, may be used as a landmark for the differentiation between the uterus and vagina in bitches.
Topics: Animals; Female; Dogs; Retrospective Studies; Prospective Studies; Uterus; Vagina; Tomography, X-Ray Computed; Adenocarcinoma
PubMed: 36434761
DOI: 10.2460/ajvr.22.03.0052 -
Zhonghua Bing Li Xue Za Zhi = Chinese... Dec 2020
Topics: Carcinoma; Female; Humans; Vagina
PubMed: 33287529
DOI: 10.3760/cma.j.cn112151-20200420-00329