-
Social Science & Medicine (1982) Aug 2021Blood collection agencies face ongoing challenges in retaining voluntary donors to meet the demand for blood and blood-related products by healthcare services. A known...
RATIONALE
Blood collection agencies face ongoing challenges in retaining voluntary donors to meet the demand for blood and blood-related products by healthcare services. A known deterrent to continued blood donation is the experience of a vasovagal reaction (VVR). However, there has been little research into donors' experiences of these reactions and the factors that influence their decision to return, which is essential information to inform strategies to improve donor return.
OBJECTIVE
The aim of this paper was to explore blood donor views and experiences of a VVR, with a particular interest in how the reaction influenced their return behaviour, using the Transactional Model of Stress and Coping.
METHODS
We conducted 34 semi-structured in-depth interviews between February and April 2018 with a sample of Australian donors who had experienced a VVR in the last seven days. Transcripts were analysed using the Framework Method.
RESULTS
The VVR elicited various emotional responses, which appeared to be influenced by social support, being aware of the possibility of experiencing a VVR, or the donation outcome. In turn, the VVR experience affected intentions to return, with those who reported more positive experiences expressing stronger intentions. Further, donors felt more likely to return if they perceived their risk of a recurrent event as low and if they were able to identify appropriate problem and emotion-focused coping strategies.
CONCLUSION
This article provides novel insights into possible ways to encourage blood donor return following a VVR.
Topics: Australia; Blood Donors; Humans; Qualitative Research; Syncope, Vasovagal
PubMed: 34153820
DOI: 10.1016/j.socscimed.2021.114142 -
Transfusion Aug 2003The effect of weight on vasovagal reaction rates has not been evaluated in high- and low-risk populations or in first-time versus repeat blood donors. In addition,... (Comparative Study)
Comparative Study
BACKGROUND
The effect of weight on vasovagal reaction rates has not been evaluated in high- and low-risk populations or in first-time versus repeat blood donors. In addition, vasovagal reaction rates and weight have not been evaluated based on solicited information.
STUDY DESIGN AND METHODS
A total of 1073 Caucasian high school students from randomly selected whole-blood drives in 2001 and 949 randomly selected Caucasian donors from the general donor population in 2001 and 2002 were subdivided into weight groups and evaluated for vasovagal reaction rates.
RESULTS
The high school population had a much higher vasovagal reaction rate than the general donor population (8.0 vs. 2.6%). The vasovagal reaction rate was inversely proportional to body weight in first-time blood donors in both populations, but the trend was not as well defined in repeat blood donors. Solicitation of information from the general donor population increased the vasovagal reaction detection rate by 2.5 times (from 2.6% to 6.5%), and it is suggested that the vasovagal reaction rate might be as high as 27 percent in first-time general donors who weighed between 110 and 139 pounds.
CONCLUSION
Body weight is a very important determinant of vasovagal reaction rates in first-time donors, but previous successful blood donation appears to mitigate the effect of body weight on vasovagal reaction rates. Solicitation of information from blood donors increases the number of vasovagal reactions detected and enhances the data.
Topics: Adolescent; Adult; Blood Donors; Body Weight; Female; Humans; Incidence; Male; Michigan; Phlebotomy; Risk Factors; Syncope, Vasovagal
PubMed: 12869114
DOI: 10.1046/j.1537-2995.2003.00478.x -
World Journal of Pediatrics : WJP Jan 2022
Topics: Child; Humans; Syncope, Vasovagal; Tilt-Table Test
PubMed: 34982400
DOI: 10.1007/s12519-021-00495-0 -
QJM : Monthly Journal of the... Dec 2016Vasovagal syncope, or the "common faint", is the most common cause of syncope. Although it is considered a benign condition, there is a significant economic burden and... (Review)
Review
Vasovagal syncope, or the "common faint", is the most common cause of syncope. Although it is considered a benign condition, there is a significant economic burden and significant impact on quality of life in patients with recurrent syncope, particularly in older adults. Typical vasovagal syncope usually occurs in young adults, and can often be diagnosed on the basis of history, in the absence of structural heart disease. Atypical vasovagal syncope, which is more common in older adults, can be more difficult to diagnose, however. In atypical vasovagal syncope, there is often a short or absent prodrome, and amnesia for loss of consciousness is common and it can, therefore, often be misdiagnosed, for example as falls. A more standardized approach to the diagnosis and management of patients presenting with syncope or unexplained falls is required, and it is anticipated that the number of Syncope Units will increase. Treatment of vasovagal syncope is largely conservative; however, medical or device therapy may be required when syncope is severe and refractory to conservative treatment, as there is significant impact on quality of life and it can be associated with injury. The aim of this article is to provide an overview of the diagnosis and management of vasovagal syncope.
Topics: Disease Management; Humans; Quality of Life; Syncope, Vasovagal
PubMed: 27340222
DOI: 10.1093/qjmed/hcw089 -
Heart (British Cardiac Society) Dec 2023
Topics: Humans; Syncope, Vasovagal; Bradycardia; Heart Rate; Tilt-Table Test
PubMed: 37591689
DOI: 10.1136/heartjnl-2023-323180 -
BMC Veterinary Research Sep 2021Corynebacterium urealyticum urinary tract infections can result in a rarely reported condition called encrusting cystitis whereby plaque lesions form on and within the...
Vasovagal reaction secondary to bladder overdistension in a dog undergoing a unique timeline of medical and surgical treatment for Corynebacterium urealyticum encrusting cystitis: a case report.
BACKGROUND
Corynebacterium urealyticum urinary tract infections can result in a rarely reported condition called encrusting cystitis whereby plaque lesions form on and within the urinary bladder mucosa. Chronic lower urinary tract signs manifest subsequent to the infection-induced cystitis and plaque-induced decreased bladder wall distensibility. Because of the organism's multidrug resistance and plaque forming capability, infection eradication can be difficult. While systemic antimicrobial therapy is the mainstay of treatment, adjunctive surgical debridement of plaques has been used with relative paucity in such cases, thereby limiting our understanding of this modality's indications and success rate. Consequently, this report describes the successful eradication of Corynebacterium urealyticum encrusting cystitis utilizing a unique timeline of medical and surgical treatments. Additionally, this represents the first reported veterinary case of a vasovagal reaction due to bladder overdistension.
CASE PRESENTATION
A 6-year-old female spayed Miniature Schnauzer was evaluated for lower urinary tract clinical signs and diagnosed with Corynebacterium urealyticum encrusting cystitis. The infection was persistent despite prolonged courses of numerous oral antimicrobials and urinary acidification. A unique treatment timeline of intravenous vancomycin, intravesical gentamicin, and mid-course surgical debridement ultimately resulted in infection resolution. During surgery, while the urinary bladder was copiously flushed and distended with saline, the dog experienced an acute vasovagal reaction from which it fully recovered.
CONCLUSIONS
Surgical debridement of bladder wall plaques should be considered a viable adjunctive therapy for Corynebacterium urealyticum encrusting cystitis cases failing to respond to systemic antibiotic therapy. The timing in which surgery was employed in this case, relative to concurrent treatment modalities, may be applicable in future cases of this disease as dictated on a case-by-case basis. If surgery is ultimately pursued, overdistension of the urinary bladder should be avoided, or at least minimized as much as possible, so as to prevent the possibility of a vasovagal reaction.
Topics: Animals; Anti-Bacterial Agents; Corynebacterium; Corynebacterium Infections; Cystitis; Dog Diseases; Dogs; Female; Syncope, Vasovagal; Urinary Bladder
PubMed: 34583703
DOI: 10.1186/s12917-021-03028-z -
Dermatologic Surgery : Official... Dec 2018A vasovagal reaction is a commonly encountered event in outpatient procedures. There is a paucity of discussion on vasovagal reactions (VVRs) in the dermatologic surgery... (Review)
Review
BACKGROUND
A vasovagal reaction is a commonly encountered event in outpatient procedures. There is a paucity of discussion on vasovagal reactions (VVRs) in the dermatologic surgery literature. However, recent investigations in the physiology, evaluation, and treatment of VVRs have been reported in other specialties.
OBJECTIVE
A comprehensive review of the physiology, evaluation, treatment, and prevention of VVRs.
MATERIALS AND METHODS
A search as performed using the PubMed/MEDLINE databases. Search terms included "vasovagal," "vasovagal reaction," "syncope," "reflex syncope," "neurocardiogenic syncope," and "fainting."
RESULTS
Studies demonstrate greater understanding in the physiology of a vasovagal reaction. Although permanent sequelae are uncommon, it is important to respond in a prompt manner. A variety of treatment and prevention options are presented.
CONCLUSION
Vasovagal reactions should be carefully evaluated. Additional studies may provide greater data in understanding and managing vasovagal reactions.
Topics: Ambulatory Surgical Procedures; Anxiety; Dermatologic Surgical Procedures; Fear; Humans; Syncope, Vasovagal
PubMed: 29994949
DOI: 10.1097/DSS.0000000000001598 -
Vaccine Sep 2022Coronavirus disease 2019 (COVID-19) vaccine administration started in February 2021 in Japan. As of December 2021, approximately 75% of the population aged ≥12 years...
Coronavirus disease 2019 (COVID-19) vaccine administration started in February 2021 in Japan. As of December 2021, approximately 75% of the population aged ≥12 years had received two doses of vaccine. We conducted a study to investigate vasovagal reactions (VVR) after COVID-19 vaccination using data on adverse events following immunization. The crude reporting rate of VVR (cases/1,000,000 doses) after vaccination was 9.6 in all age groups combined, and was more frequent in the younger age groups: 28.6 and 37.2 in individuals aged 10-19 years and 20-29 years, respectively. In individuals aged 10-29 years, the rate was similar in males and females (33.0 and 34.2, respectively, p = 0.53); but was higher after dose 1 than after dose 2 (57.4 and 8.8, respectively, p < 0.001). Based on these results, caution needs to be exercised when vaccinating adolescents and young adults, especially with dose 1 of COVID-19 vaccines.
Topics: Adolescent; Adult; COVID-19; COVID-19 Vaccines; Child; Female; Humans; Japan; Male; Syncope, Vasovagal; Vaccination; Young Adult
PubMed: 36068111
DOI: 10.1016/j.vaccine.2022.08.056 -
Trends in Cardiovascular Medicine Nov 2018The benefit of conventional pacing in vasovagal syncope remains controversial and is currently recommended for patients with recurrent syncope and documented asystole.... (Review)
Review
The benefit of conventional pacing in vasovagal syncope remains controversial and is currently recommended for patients with recurrent syncope and documented asystole. In the last two decades, a growing body of evidence has emerged supporting the use of a new sensing technique called closed loop stimulation or CLS, to treat refractory vasovagal syncope. CLS uses a sensing algorithm that can detect variation in cardiac contractility and respond to drop in blood pressure by increasing the heart rate. Multiple observational and randomized studies have assessed its efficacy and showed its superiority to conventional pacing in reducing the burden of syncopal attacks in patients with cardio-inhibitory vasovagal syncope.
Topics: Algorithms; Cardiac Pacing, Artificial; Clinical Decision-Making; Equipment Design; Hemodynamics; Humans; Pacemaker, Artificial; Remote Sensing Technology; Signal Processing, Computer-Assisted; Syncope, Vasovagal; Treatment Outcome
PubMed: 29843961
DOI: 10.1016/j.tcm.2018.05.003 -
Expert Review of Cardiovascular Therapy Dec 2014Vasovagal syncope (VVS) is a common form of fainting. The pathophysiology of VVS is complex and involves changes in the autonomic and vascular tone, resulting in reflex...
Vasovagal syncope (VVS) is a common form of fainting. The pathophysiology of VVS is complex and involves changes in the autonomic and vascular tone, resulting in reflex bradycardia with marked hypotension. Paradoxical peripheral vasodilation caused by endothelial dysfunction may also play a key role in inappropriate hypotension during VVS. Endothelial hyperactivity due to up regulation of nitric oxide synthase leads to profound vasodilation, much stronger than vasodilation caused by adrenergic stimulation in response to orthostatic stress alone. Studies have reported significantly higher flow-mediated dilation and higher plasma nitric oxide concentration in people with vasovagal syndrome. Patients with VVS showed decreased vasoconstrictive agent endothelin-1 levels during orthostatic stress. Coagulation and fibrinolysis activity also play important roles in endothelial function in syncopal patients. The response of the endothelium to orthostatic stress is similar to the reaction to haemorrhagic stress and is likely to be a remnant from the evolutionary adaptation of primates.
Topics: Autonomic Nervous System; Endothelium; Humans; Hypotension, Orthostatic; Stress, Physiological; Syncope, Vasovagal; Vasodilation
PubMed: 25410020
DOI: 10.1586/14779072.2014.982095