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Cardiology Clinics Feb 2010Several new-generation percutaneous support devices are available or are in different stages of development for use in high-risk percutaneous coronary intervention... (Review)
Review
Several new-generation percutaneous support devices are available or are in different stages of development for use in high-risk percutaneous coronary intervention (PCI), cardiogenic shock, and for other indications. Preliminary studies have demonstrated the feasibility and safety of these devices and the beneficial effect on hemodynamic parameters. In this article, the authors discuss (1) the percutaneous circulatory support devices presently available and routinely used in the catheterization laboratory, (2) the technical aspects involved with insertion and removal, and (3) relevant data from randomized trials, meta-analyses, and registries about the benefits of their use in patients with cardiogenic shock complicating ST segment elevation myocardial infarction and in those with significant left ventricular systolic dysfunction undergoing complex PCI.
Topics: Cardiac Catheterization; Cardiac Output; Equipment Design; Heart-Assist Devices; Humans; Intra-Aortic Balloon Pumping; Ventricular Dysfunction, Left
PubMed: 19962057
DOI: 10.1016/j.ccl.2009.09.007 -
The Annals of Thoracic Surgery Oct 1995Low output syndrome after cardiac operations is associated with high morbidity and mortality rates. The contribution of right ventricular dysfunction to this syndrome...
BACKGROUND
Low output syndrome after cardiac operations is associated with high morbidity and mortality rates. The contribution of right ventricular dysfunction to this syndrome has not been fully characterized. The purpose of this study was to evaluate the utility of transesophageal echocardiography to identify the frequency and the in-hospital mortality from right ventricular dysfunction in patients with this syndrome.
METHODS
Seventy-five consecutive patients undergoing transesophageal echocardiography for low output syndrome early after cardiac operations were evaluated. The findings from transesophageal echocardiography were correlated with the type of surgical procedure, cross-clamp time, right heart hemodynamics, and coronary angiography.
RESULTS
Right ventricular systolic dysfunction occurred in 36 patients (42%); in 17 patients it was isolated and in 19 patients it occurred in combination with left ventricular dysfunction. Postoperative right ventricular dysfunction was not uniformly associated with important right coronary artery disease or with prolonged ischemic time during cardiopulmonary bypass. Hemodynamic data were not useful to distinguish the group with postoperative right ventricular dysfunction. Patients with right ventricular dysfunction had a high (44%) in-hospital mortality rate.
CONCLUSIONS
Right ventricular dysfunction occurs frequently in patients with low output syndrome after cardiac operations and is associated with a high in-hospital mortality rate. Better understanding of the mechanisms causing postoperative right ventricular dysfunction may provide insight for preventing this complication.
Topics: Adult; Aged; Aged, 80 and over; Cardiac Output, Low; Cardiac Surgical Procedures; Coronary Angiography; Echocardiography, Transesophageal; Female; Hemodynamics; Humans; Male; Middle Aged; Postoperative Complications; Ventricular Dysfunction, Left; Ventricular Dysfunction, Right
PubMed: 7574953
DOI: 10.1016/0003-4975(95)00526-q -
Current Opinion in Cardiology May 2009Isolated left ventricular noncompaction (LVNC) is a myocardial disorder characterized by excessive and prominent trabeculations of the left ventricle, associated with... (Review)
Review
PURPOSE OF REVIEW
Isolated left ventricular noncompaction (LVNC) is a myocardial disorder characterized by excessive and prominent trabeculations of the left ventricle, associated with progressive systolic failure, stroke and arrhythmia. Until quite recently, LVNC was thought to be extremely rare, but, with greater awareness of the disease and improvements in echocardiographic technology, there has been a dramatic increase in the frequency of diagnosis. Recent studies suggest that the frequency of LVNC is determined in part by the diagnostic criteria used.
RECENT FINDINGS
Up to 50% of adult patients with LVNC have mutations in genes encoding proteins of the cardiac sarcomere, suggesting that LVNC might represent a new disease paradigm in which mutations that more typically cause dilated and hypertrophic cardiomyopathies result in abnormal ventricular morphogenesis.
SUMMARY
In this review, we briefly summarize current clinical literature on LVNC, with a particular focus on the limitations of current diagnostic criteria and emerging data on the genetics of the disorder.
Topics: Humans; Ventricular Dysfunction, Left
PubMed: 19318934
DOI: 10.1097/HCO.0b013e32832a11e7 -
The American Journal of Cardiology Sep 2010In patients with corrected tetralogy of Fallot (cToF), left ventricular (LV) dysfunction is closely related to right ventricular (RV) dysfunction, indicating adverse...
In patients with corrected tetralogy of Fallot (cToF), left ventricular (LV) dysfunction is closely related to right ventricular (RV) dysfunction, indicating adverse ventricular-ventricular interactions. However, the mechanism that links RV dysfunction to LV dysfunction remains unclear. In this prospective study, 32 patients with cToF and 19 controls were enrolled. With cardiac magnetic resonance imaging, biventricular ejection fractions were assessed. Using 2-dimensional speckle tracking, global and regional RV and LV strains and LV twist were assessed. To detect and characterize ventricular-ventricular interaction, the relation between global and regional RV mechanics and global and regional LV mechanics was assessed. Global RV strain, global LV strain, and LV twist were decreased in patients with cToF. Global RV strain correlated with global LV strain (r = 0.66, p <0.001) and LV twist (r = -0.72, p <0.001), indicating the presence of adverse ventricular-ventricular interaction. Furthermore, close relations were observed between apical RV strain and apical LV strain (r = 0.62, p <0.001) and apical LV rotation (r = -0.67, p <0.001). In conclusion, RV strain was significantly related to LV strain and LV twist in patients with cToF and controls. Furthermore, apical RV strain correlated with apical LV strain and apical LV rotation, indicating adverse apical ventricular-ventricular interactions.
Topics: Adolescent; Case-Control Studies; Child; Cohort Studies; Echocardiography, Doppler, Color; Female; Humans; Magnetic Resonance Imaging; Male; Stress, Mechanical; Stroke Volume; Tetralogy of Fallot; Ventricular Dysfunction, Left; Ventricular Dysfunction, Right; Ventricular Remodeling
PubMed: 20723653
DOI: 10.1016/j.amjcard.2010.04.032 -
Journal of Cardiac Failure Feb 2006
Review
Topics: Cardiac Output, Low; Humans; Ventricular Dysfunction
PubMed: 16500567
DOI: 10.1016/j.cardfail.2005.11.009 -
Heart Rhythm Jan 2023
Topics: Humans; Transcatheter Aortic Valve Replacement; Ventricular Function, Left; Ventricular Dysfunction, Left
PubMed: 35988906
DOI: 10.1016/j.hrthm.2022.08.014 -
Revista Espanola de Cardiologia Jun 2007
Topics: Humans; Sleep Apnea, Obstructive; Ultrasonography; Ventricular Dysfunction
PubMed: 17580044
DOI: 10.1157/13107112 -
Cardiology Clinics Feb 2016Phase analysis of gated myocardial perfusion single-photon emission computed tomography is a widely available and reproducible measure of left ventricular (LV)... (Review)
Review
Phase analysis of gated myocardial perfusion single-photon emission computed tomography is a widely available and reproducible measure of left ventricular (LV) dyssynchrony, which also provides comprehensive assessment of LV function, global and regional scar burden, and patterns of LV mechanical activation. Preliminary studies indicate potential use in predicting cardiac resynchronization therapy response and elucidation of mechanisms. Because advances in technology may expand capabilities for precise LV lead placement in the future, identification of specific patterns of dyssynchrony may have a critical role in guiding cardiac resynchronization therapy.
Topics: Cardiac Imaging Techniques; Cardiac Resynchronization Therapy; Humans; Tomography, Emission-Computed, Single-Photon; Ventricular Dysfunction, Left; Ventricular Function, Left
PubMed: 26590783
DOI: 10.1016/j.ccl.2015.08.006 -
Journal of Cardiothoracic and Vascular... Mar 2020To find out if there are any differences in biomarkers between severe isolated right ventricular (RV) dysfunction and severe isolated left ventricular (LV) dysfunction... (Observational Study)
Observational Study
OBJECTIVE
To find out if there are any differences in biomarkers between severe isolated right ventricular (RV) dysfunction and severe isolated left ventricular (LV) dysfunction after cardiac surgery using cardiopulmonary bypass.
DESIGN
Observational study.
SETTING
Teaching hospital.
PARTICIPANTS
A total of 46 patients who had severe isolated RV or LV dysfunction after cardiac surgery.
INTERVENTION
The authors collected perioperative clinical and biomarker data.
MEASUREMENTS AND MAIN RESULTS
Severe isolated RV dysfunction patients (n = 20) had higher postoperative direct bilirubin (p = 0.030), total bilirubin (p = 0.044), glucose (p = 0.011), and international normalized ratio (INR) (p = 0.050) by repeated measure analysis of variance when compared with patients with severe isolated LV dysfunction (n = 26). The RV group also showed lower preoperative alanine transferase (19.3 ± 1.5 v 32.7 ± 4.2, p = 0.001), higher 4-hour INR (1.5 ± 0.3 v 1.4 ± 0.2, p = 0.008), and higher 48-hour INR (1.8 ± 0.4 v 1.4 ± 0.1, p < 0.001). None in the LV group died, whereas 4 patients in the RV group died (all of them had preoperative atrial fibrillation and underwent double valve replacement surgery).
CONCLUSION
The authors observed biomarkers differences between severe isolated RV dysfunction and severe isolated RV dysfunction.
Topics: Biomarkers; Cardiac Surgical Procedures; Cardiopulmonary Bypass; Humans; Ventricular Dysfunction, Left; Ventricular Dysfunction, Right
PubMed: 31473115
DOI: 10.1053/j.jvca.2019.07.128 -
Arquivos Brasileiros de Cardiologia Nov 1996
Topics: Heart Failure; Humans; Time Factors; Ventricular Dysfunction
PubMed: 9239864
DOI: No ID Found