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Journal Des Sciences Medicales de Lille Jan 1962
Topics: Adenoma; Adrenal Gland Neoplasms; Adrenal Glands; Adrenocortical Adenoma; Female; Humans; Medical Records; Virilism
PubMed: 14462132
DOI: No ID Found -
JAMA Dec 1982
Topics: 17-Ketosteroids; Adrenal Cortex Neoplasms; Adrenal Glands; Adrenal Hyperplasia, Congenital; Atrophy; Carcinoma; Child; Female; Humans; Virilism
PubMed: 7143691
DOI: 10.1001/jama.248.23.3140 -
Journal of Paediatrics and Child Health Jun 2022
Topics: Female; Humans; Infant, Newborn; Virilism
PubMed: 34651366
DOI: 10.1111/jpc.15753 -
Clinical Pediatrics Sep 2023
Topics: Female; Humans; Virilism; Puberty; Puberty, Precocious
PubMed: 36797848
DOI: 10.1177/00099228221146508 -
Indian Journal of Cancer 2016
Topics: Adolescent; Adrenocortical Adenoma; Female; Humans; Neoplasms, Glandular and Epithelial; Virilism
PubMed: 27146779
DOI: 10.4103/0019-509X.180848 -
Journal of Pediatric Endocrinology &... Apr 2016Adrenocortical tumors are neoplasms that rarely occur in pediatric patients. Adrenocortical carcinoma (ACC) is even more uncommon, and is an aggressive malignancy with...
Adrenocortical tumors are neoplasms that rarely occur in pediatric patients. Adrenocortical carcinoma (ACC) is even more uncommon, and is an aggressive malignancy with 5-year survival of 55% in a registry series. There is a lack of information on long-term endocrine outcome in survivors. We describe a 10-year follow-up in a patient who presented at 3 years 5 months with a 1-year history of axillary odor and 6 months' history of pubic hair development with an increased clitoral size. Androgen levels were increased and a pelvic sonogram revealed a suprarenal mass of the left kidney. The tumor was successfully removed. At 6 years 11 months, androgen levels increased again. Workup for tumor recurrence was negative and the findings likely represented early adrenarche. The patient had menarche at an appropriate time and attained a height appropriate for her family.
Topics: Adrenal Cortex Neoplasms; Adrenalectomy; Adrenocortical Carcinoma; Child, Preschool; Female; Humans; Menarche; Prognosis; Puberty; Virilism
PubMed: 26812773
DOI: 10.1515/jpem-2015-0123 -
Andrology May 2019Human fertility has always been a topic of curiosity and devotion. Many cultures consider fertility to be a necessity for the survival and perpetuation of mankind and... (Review)
Review
BACKGROUND
Human fertility has always been a topic of curiosity and devotion. Many cultures consider fertility to be a necessity for the survival and perpetuation of mankind and since early times, myths were created to explain this fabulous process. Fertility gods were ubiquitous in numerous ancient human cultures and were used both to understand fertility and to cope with infertility by means of rituals and offerings.
OBJECTIVES
This manuscript aims to catalog and describe the deities associated with male fertility and virility.
MATERIAL AND METHODS
We conducted a comprehensive search for the terms "male fertility god" and "male virility god" on the internet using web-based search engines. Based on the information retrieved, we selected those deities directed related to male fertility and/or virility and further deepened the search using Pubmed and Medline databases for peer-reviewed articles as well as books and articles about ancient mythology.
RESULTS
We identified several gods linked to male fertility and virility in various cultures from Egypt, Greece, Rome, India, Southwestern United States, France, Colombia and Buthan..
DISCUSSION
Most of these deities were depicted with an erect phallus and with other fertility symbols like snakes. Some deities were also associated with plants and/or animal fertility and their festivals were often held during the harvest period.
CONCLUSION
Gods of male fertility and virility played important roles in many ancient cultures. Offerings and rituals to these gods were the only available options to deal with problems of reproduction and demonstrate the lengths to which ancient people would go seeking cures for infertility.
Topics: Fertility; History, Ancient; Humans; Male; Masculinity; Mythology
PubMed: 30786174
DOI: 10.1111/andr.12599 -
Journal of Pediatric Endocrinology &... Sep 2009
Topics: Adrenal Cortex Neoplasms; Adrenocortical Adenoma; Age Determination by Skeleton; Female; Humans; Infant; Virilism
PubMed: 19960887
DOI: 10.1515/jpem.2009.22.9.779 -
Cancer Jul 1977A 43-year-old man with a 36-year history of virilization due to an adrenal carcinoma is presented. The initial presentation at age 7 with precocious puberty and...
A 43-year-old man with a 36-year history of virilization due to an adrenal carcinoma is presented. The initial presentation at age 7 with precocious puberty and epiphyseal bone fusion suggested increased androgen effect at a very early age. The patient's 36-year course before his death suggested either a very slow growing adrenal carcinoma or untreated congenital adrenal hyperplasia that progressed to an adrenal carcinoma. Endocrine evaluation showed markedly increased DHEA and DHEA-sulfate levels. These were associated with elevated plasma and urinary estradiol levels and suppressed LH and FSH plasma concentrations. The 24-hour mean levels of cortisol and testosterone were normal. Studies of the circadian periodicity of cortisol showed a disturbed temporal pattern but a normal 24-hour mean concentration that correlated with a normal cortisol production rate. The 24-hour LH secretory pattern showed a decrease in the normal episodic fluctuation of this hormone over the 24-hour period.
Topics: Adrenal Cortex Neoplasms; Adrenal Gland Neoplasms; Adult; Carcinoma; Circadian Rhythm; Dehydroepiandrosterone; Estradiol; Follicle Stimulating Hormone; Humans; Hydrocortisone; Luteinizing Hormone; Male; Testosterone; Time Factors; Virilism
PubMed: 141975
DOI: 10.1002/1097-0142(197707)40:1<307::aid-cncr2820400143>3.0.co;2-2 -
Endocrinologia Japonica Feb 1978Pregnant rats were given daily a subcutaneous injection of methyltestosterone for 4 days from the 17th to the 20th day of gestation, and were allowed to be delivered to...
Pregnant rats were given daily a subcutaneous injection of methyltestosterone for 4 days from the 17th to the 20th day of gestation, and were allowed to be delivered to their offsprings (F1) which were used for the examination of later reproductive functioning. When observed for 21 weeks after birth, the growth rate of F1 from methyltestosterone-treated groups was higher than that of F1 from the control group. The anogenital distance in 50-microgram-treated F1 females started to become significantly longer on the 14th day and in 5-microgram-treated F1 females on the 28th day after birth than that in F1 from the control. The day on which vaginal opening took place in 50% of females was 34.4 days of age in both the control and the 5 microgram groups, but it delayed until 40.7 days in the 50 microgram group. Furthermore, persistent estrus was observed after about 90 days of age in the 50 microgram group. This persistent estrus disappeared by placing these females with males, resulting no pregnancy. In the 5 microgram group females could be pregnant, but their female fetuses (F2), when examined on the 21st day of gestation, had significantly shortened the length of the urovaginal septum. The observations show that virilization can be induced in the third generation.
Topics: Animals; Body Weight; Estrus; Female; Maternal-Fetal Exchange; Methyltestosterone; Pregnancy; Rats; Reproduction; Virilism
PubMed: 639752
DOI: 10.1507/endocrj1954.25.1