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Journal Francais D'ophtalmologie Nov 2023
Topics: Humans; Vitreous Body; Male; Postoperative Complications; Female; Foreign-Body Migration
PubMed: 37164874
DOI: 10.1016/j.jfo.2023.01.032 -
Ophthalmology. Retina Jan 2018
Topics: Cataract Extraction; Humans; Male; Middle Aged; Postoperative Complications; Tomography, Optical Coherence; Vitrectomy; Vitreous Body
PubMed: 31047308
DOI: 10.1016/j.oret.2017.09.005 -
Annales D'oculistique Dec 1971
Topics: Animals; Connective Tissue; Cytoplasm; Cytoplasmic Granules; Glycosaminoglycans; Histocytochemistry; Humans; Microscopy, Phase-Contrast; Microscopy, Polarization; Staining and Labeling; Swine; Vitreous Body
PubMed: 4113784
DOI: No ID Found -
Ophthalmologica. Journal International... 1973
Review
Topics: Cells, Cultured; Connective Tissue Cells; Histocytochemistry; Humans; Injections; Methods; Vitreous Body
PubMed: 4581187
DOI: 10.1159/000306874 -
Mediators of Inflammation 2012The eye is a well-suited organ for local delivery of therapeutics to treat vitreous inflammation as well as other pathologic conditions that induce visual loss. Several... (Review)
Review
The eye is a well-suited organ for local delivery of therapeutics to treat vitreous inflammation as well as other pathologic conditions that induce visual loss. Several conditions are particularly challenging to treat and often require chronic courses of therapy. The use of implantable intravitreal devices for drug delivery is an emerging field in the treatment of vitreous inflammation as well as other ophthalmologic diseases. There are unique challenges in the design of these devices which include implants, polymers, and micro- and nanoparticles. This paper reviews current and investigational drug delivery systems for treating vitreous inflammation as well as other pathologic conditions that induce visual loss. The use of nonbiodegradable devices such as polyvinyl alcohol-ethylene vinyl acetate polymers and polysulfone capillary fibers, and biodegradable devices such as polylactic acid, polyglycolic acid, and polylactic-co-glycolic acid, polycaprolactones, and polyanhydrides are reviewed. Clinically used implantable devices for therapeutic agents including ganciclovir, fluocinolone acetonide, triamcinolone acetonide, and dexamethasone are described. Finally, recently developed investigational particulate drug delivery systems in the form of liposomes, microspheres, and nanoparticles are examined.
Topics: Animals; Drug Delivery Systems; Humans; Inflammation; Polymers; Vitreous Body
PubMed: 22988344
DOI: 10.1155/2012/126463 -
Current Opinion in Ophthalmology May 2017Visualization remains a critical factor in successful ocular surgery.Here we review new technology that has the potential to allow for safer and more efficient retinal... (Review)
Review
PURPOSE OF REVIEW
Visualization remains a critical factor in successful ocular surgery.Here we review new technology that has the potential to allow for safer and more efficient retinal surgery.
RECENT FINDINGS
Vitreoretinal surgery poses unique visualization challenges such as the need for specialized optical systems and the delicate and microscopic features of retinal structures. Better retinal visualization allows for new approaches to increasingly complex retinal cases. Wide-angle viewing has allowed stereopic visualization of the peripheral retina. Improved lighting systems have shown better safety profiles and can facilitate bimanual techniques. The potential to improve surgical decision making has been shown with intraoperative imaging such as optical coherence tomography.
SUMMARY
Although some of the benefits of these developments have yet to be proven, improved technology for visualization during retinal surgery will hopefully allow for safer and more efficient surgeries.
Topics: Humans; Retina; Tomography, Optical Coherence; Vitreoretinal Surgery; Vitreous Body
PubMed: 28306625
DOI: 10.1097/ICU.0000000000000368 -
Archives of Ophthalmology (Chicago,... Sep 1959
Topics: Humans; Male; Vitreous Body
PubMed: 14426195
DOI: 10.1001/archopht.1959.04220030012003 -
Experimental and Clinical Endocrinology... Apr 2020It has been estimated that 15% up to one third of cases of deaths due to diabetic ketoacidosis occur in individuals with so far unknown diabetes. Moreover, cardiac... (Review)
Review
It has been estimated that 15% up to one third of cases of deaths due to diabetic ketoacidosis occur in individuals with so far unknown diabetes. Moreover, cardiac arrhythmias that occur during nocturnal hypoglycaemia include bradycardia and ectopics that may provoke lethal arrhythmias. As postmortem capillary glucose concentrations have no diagnostic value, the postmortem forensic proof of hyperglycaemia or hypoglycaemia remains a challenge. The established but rarely applied method of postmortem determination of glucose and lactate in vitreous humor with or without calculation of the sum formula of Traub could provide reliable exclusion or proof of severe antemortem disorders in glucose metabolism. To date, diagnostic puncture of vitreous humor is more established for the postmortem detection of diabetic ketoacidosis than for the exclusion or proof of lethal hypoglycaemia. Vitreous humor is protected from postmortem degradation and contamination due to its isolated localization. The autolytic process in vitreous humor is considerably delayed compared to blood or liquor. In vitreous humor also the triggering agent of hypoglycaemia (insulin, insulin analogues) is easier to be detected than in blood since insulins are very unstable in postmortem blood. Furthermore, parameters of long term glycaemic control such as 1,5-anhydroglucitol, HbA1c and fructosamine can be determined in vitreous humor. However, limitations and interference factors of this method should be carefully considered. So far, clinical diabetology has taken no broad notice of this useful forensic procedure.
Topics: Diagnosis; Glucose Metabolism Disorders; Humans; Vitreous Body
PubMed: 30340233
DOI: 10.1055/a-0752-0028 -
Archives of Ophthalmology (Chicago,... Nov 1970
Review
Topics: Abnormalities, Multiple; Accommodation, Ocular; Animals; Aqueous Humor; Cataract; Cataract Extraction; Collagen; Glaucoma; Humans; Intraocular Pressure; Lens, Crystalline; Methods; Retinal Detachment; Silicones; Ultrasonic Therapy; Ultrasonography; Vitreous Body
PubMed: 4920781
DOI: 10.1001/archopht.1970.00990040677023 -
Survey of Ophthalmology 2020Vitreous floaters are common, related to age, myopia, genetic predisposition, and infiltration of the vitreous body. A subset of patients report symptoms impacting their... (Review)
Review
Vitreous floaters are common, related to age, myopia, genetic predisposition, and infiltration of the vitreous body. A subset of patients report symptoms impacting their quality of vision. Treatment with laser vitreolysis, the use of an Nd:YAG laser to vaporize the collagenous vitreous opacities appears to be used more frequently; however, data regarding long-term safety and effectiveness are lacking. We present currently available data regarding efficacy and safety, as well as additional considerations. Laser vitreolysis of symptomatic floaters should not be routinely performed without additional studies documenting its safety and long-term efficacy. Ideally, the procedure would be effective in most patients and be approved by the Food and Drug Administration based on the results of a Food and Drug Administration registration trial before widespread adoption.
Topics: Eye Diseases; Humans; Laser Therapy; Lasers, Solid-State; Visual Acuity; Vitrectomy; Vitreous Body
PubMed: 32135173
DOI: 10.1016/j.survophthal.2020.02.007