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Journal of Investigative Medicine High... 2019We describe a case of acute erosive vulvovaginitis accompanying Borrelia burgdorferi infection. The patient is a 57-year-old woman previously diagnosed with Lyme disease...
We describe a case of acute erosive vulvovaginitis accompanying Borrelia burgdorferi infection. The patient is a 57-year-old woman previously diagnosed with Lyme disease who presented with a painful erosive genital lesion. At the time of the outbreak, she was being treated with oral antibiotics, and she tested serologically positive for B burgdorferi and serologically negative for syphilis. Histological examination of biopsy tissue from the lesion was not characteristic of dermatopathological patterns typical of erosive vulvar conditions. Dieterle-stained biopsy sections revealed visible spirochetes throughout the stratum spinosum and stratum basale, and anti- B burgdorferi immunostaining was positive. Motile spirochetes were observed by darkfield microscopy and cultured in Barbour-Stoner-Kelly-complete medium inoculated with skin scrapings from the lesion. Cultured spirochetes were identified genetically as B burgdorferi sensu stricto by polymerase chain reaction, while polymerase chain reaction amplification of treponemal gene targets was negative. The condition resolved after treatment with additional systemic antibiotic therapy and topical antibiotics. In cases of genital ulceration that have no identifiable etiology, the possibility of B burgdorferi spirochetal infection should be considered.
Topics: Biopsy; Borrelia burgdorferi; DNA, Bacterial; Female; Humans; Lyme Disease; Middle Aged; Polymerase Chain Reaction; Vulvovaginitis
PubMed: 31043089
DOI: 10.1177/2324709619842901 -
BMJ (Clinical Research Ed.) Jan 2005
Review
Topics: Candidiasis; Child; Enterobiasis; Female; Haemophilus Infections; Humans; Puberty; Staphylococcal Infections; Streptococcal Infections; Vulvovaginitis
PubMed: 15661783
DOI: 10.1136/bmj.330.7484.186 -
Medicina Clinica Oct 1994
Review
Topics: Candidiasis, Vulvovaginal; Female; Humans; Recurrence
PubMed: 7996909
DOI: No ID Found -
European Journal of Pediatrics Dec 2022Vulvovaginitis is a common and challenging gynaecological problem in prepubertal and pubertal girls. Such an infection, owing to a wide range of aetiologies, if not...
UNLABELLED
Vulvovaginitis is a common and challenging gynaecological problem in prepubertal and pubertal girls. Such an infection, owing to a wide range of aetiologies, if not responding to hygienic measures, needs further investigation through vaginal cultures, since treatment should be tailored accordingly. This study aimed to investigate the pathogens isolated in prepubertal and pubertal girls with signs and symptoms of vulvovaginitis. A total of 2314 symptomatic girls, 1094 prepubertal and 1220 pubertal, aged 2 to 16 years, were included. Vaginal samples were inoculated on specific culture plates followed by incubation in aerobic, anaerobic or CO atmosphere at 37 °C for 24 or 48 h, as appropriate. The identification of the isolated pathogens was carried out using Gram stain, conventional methods and the automated system VITEK 2 (BioMerieux, Marcy l'Etoile, France). Positive cultures were obtained from 587 (53.7%) of prepubertal girls and 926 (75.9%) of pubertal girls. A total of 613 and 984 pathogens were detected in prepubertal and pubertal subjects, respectively. Isolated bacteria included 40.1% and 22.8% Gram-positive cocci, 35.6% and 24.8% Gram-negative rods in the prepubertal and pubertal groups, respectively, with faecal pathogens being the most prevalent. Bacterial vaginosis was diagnosed in 22.8% of prepubertal and 37.9% of pubertal girls. Candida species were isolated mostly in the pubertal girls (14.5%).
CONCLUSION
Culture results should be evaluated with caution in children with vulvovaginitis. In the prepubertal girls, the most common isolated pathogens were opportunistic bacteria of faecal origin while girls in late puberty were more susceptible to bacterial vaginosis and vulvovaginal candidiasis.
WHAT IS KNOWN
• Vulvovaginitis is the most frequent and challenging reason for referral to paediatric and adolescent gynaecology services. • Microbiological examination can prove to be a significant tool to help diagnosis although results should be evaluated with caution in children.
WHAT IS NEW
• Significantly more positive vaginal cultures and pathogens were recorded in symptomatic pubertal girls compared to prepubertal children. • The prevalence of bacterial vaginosis was increased in both prepubertal and pubertal girls with vulvovaginitis although significantly more in girls at puberty.
Topics: Adolescent; Female; Child; Humans; Male; Vaginosis, Bacterial; Vulvovaginitis; France
PubMed: 36163515
DOI: 10.1007/s00431-022-04631-4 -
Journal of Pediatric and Adolescent... Dec 2022The diagnosis and treatment of vulvovaginitis in children is poorly managed because it is difficult to determine whether the agent causing vulvovaginal inflammation is a...
BACKGROUND
The diagnosis and treatment of vulvovaginitis in children is poorly managed because it is difficult to determine whether the agent causing vulvovaginal inflammation is a single bacterial species.
STUDY OBJECTIVE
This study retrospectively evaluated genital microbiological findings in prepubescent girls with vulvovaginitis and then compared the findings to healthy controls without discharge.
METHODS
This was a retrospective case-control study of 483 prepubescent girls aged 2-10 years with vulvovaginitis and 50 age-matched healthy asymptomatic controls. Data were collected at the Pediatric General Outpatient Unit of the Hospital of the Bezmialem Vakıf University from December 2015 to March 2021.
RESULTS
Of the 483 positive vaginal cultures in the study group, 248 (51.3%) exhibited potential causative agents. Conversely, 8 of 50 (16%) of the vaginal cultures in the control group (P < .001) exhibited potential causative agents. Streptococcus pyogenes was the most frequently detected causative agent of vulvovaginitis in the study group. S. pyogenes was present in specimens from 74 girls (15.8%) with symptoms of vulvovaginitis vs 1 (4.1%) specimen in the control group. Other specific organisms identified in the study group were Escherichia coli (12%), Haemophilus influenzae (5%), Staphylococcus aureus (4.3%), Candida albicans (4.3%), and Streptococcus agalactia (3.3%).
CONCLUSIONS
Among prepubescent girls with vulvovaginitis, 51.3% of vaginal cultures exhibited potential causative agents in the study group. Our microbiological data indicated that the most common pathogens were S. pyogenes and E. coli.
Topics: Child; Female; Humans; Retrospective Studies; Escherichia coli; Case-Control Studies; Vulvovaginitis; Streptococcus pyogenes
PubMed: 35820605
DOI: 10.1016/j.jpag.2022.07.005 -
Pakistan Journal of Biological Sciences... Apr 2012Vulvovaginitis is the most common gynecologic condition seen by practitioners rendering primary care to women. Vulvovaginitis Candidiasis (VVC) is the most common type...
Vulvovaginitis is the most common gynecologic condition seen by practitioners rendering primary care to women. Vulvovaginitis Candidiasis (VVC) is the most common type of vaginitis and this study aimed at specifying VVC recurrence during pregnancy. In this prospective study, 150 pregnant women suffering from vaginal excretion, morsus and itching were studied. Initially, the patients were treated using clotrimazole local cream (5 g) for 7 successive days. After initial treatment, the patients were freely visited once a month until delivery considering vaginitis symptoms and VVC recurrence was examined during pregnancy. Mean age of the understudy mothers was 27.26 +/- 3.76. Mean of recurrence number was 0.17 +/- 0.48 during the first trimester. Mean of recurrence number was 0.92 +/- 0.76 during the second trimester. Mean of recurrence number was 2.16 +/- 0.63 during the third trimester. Statistically significant difference was between recurrences during three trimesters of pregnancy (p < 0.001). There is statistically significant difference between mean number of recurrences during three trimesters of pregnancy.
Topics: Adult; Candidiasis, Vulvovaginal; Female; Humans; Pregnancy; Pregnancy Complications, Infectious; Recurrence
PubMed: 24199471
DOI: 10.3923/pjbs.2012.399.402 -
Journal of Pediatric and Adolescent... Feb 1997To evaluate cases of vulvovaginitis treated in our institutions.
STUDY OBJECTIVE
To evaluate cases of vulvovaginitis treated in our institutions.
DESIGN
Follow-up of 1,778 cases of vulvovaginitis to investigate the prevalence of various pathogens involved in the disease.
SETTING
Divisions of pediatric and adolescent gynecology, university hospitals of Crete and Athens, Greece.
PARTICIPANTS
Girls 1-18 years old seen at the clinics of the above institutions.
INTERVENTIONS
None.
MAIN OUTCOME MEASURES
Vaginal culture, cytology, and vaginoscopy.
RESULTS
Vulvovaginitis was encountered in 61.8% of the gynecological problems seen during childhood and adolescence. Infections were usually located in both the vulva and the vagina (56.9%). The main symptoms were vaginal discharge (53%), erythema (33%), and pruritus (27%). Candida spp (23.0%), beta-hemolytic Streptococci group B (15.0%), and Enterococci spp (10.0%) were the most frequent pathogens involved in the disease.
CONCLUSIONS
Vulvovaginitis is a common disease during childhood and adolescence. Effective treatment, reassurance, and appropriate consultation based on the prevention of relapses are the most important steps for the management of the disease.
Topics: Adolescent; Bacterial Infections; Candidiasis, Vulvovaginal; Child; Child, Preschool; Female; Follow-Up Studies; Greece; Humans; Infant; Prevalence; Vagina; Vulvovaginitis
PubMed: 9061634
DOI: 10.1016/s1083-3188(97)70043-3 -
Ginekologia Polska Dec 2009Vulvovaginitis is the most common cause of gynecological complaints in young girls. Factors which cause vulvovaginitis include, among other things, low level of sexual... (Review)
Review
Vulvovaginitis is the most common cause of gynecological complaints in young girls. Factors which cause vulvovaginitis include, among other things, low level of sexual hormones (hypoestrogenism), the anatomical proximity of the rectum and delicate vulvar skin and vaginal mucosa. Usually vulvovaginitis in young girls is caused by non-specific factors. The aim of the study was to present the most frequent causes of vulvovaginitis in young girls.
Topics: Adolescent; Age Factors; Anti-Bacterial Agents; Child; Child Welfare; Child, Preschool; Female; Humans; Risk Factors; Vulvovaginitis
PubMed: 20120939
DOI: No ID Found -
Soins; La Revue de Reference Infirmiere Feb 1985
Topics: Adult; Female; Humans; Vulvovaginitis
PubMed: 3847135
DOI: No ID Found -
La Revue Du Praticien Oct 1996
Topics: Adolescent; Adult; Aged; Candidiasis, Vulvovaginal; Child; Child, Preschool; Chlamydia Infections; Diagnosis, Differential; Female; Gonorrhea; Herpes Genitalis; Humans; Middle Aged; Risk Factors; Sexual Partners; Trichomonas Infections; Vulvovaginitis
PubMed: 8978203
DOI: No ID Found