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Clinical Case Reports Dec 2020Oncocytic adenolipoma is a rare tumor to occur in the salivary gland, which can present as a giant neck mass. Until now, <20 such cases are reported. We report this rare...
Oncocytic adenolipoma is a rare tumor to occur in the salivary gland, which can present as a giant neck mass. Until now, <20 such cases are reported. We report this rare case for surgeons to consider it as one of the differential diagnoses.
PubMed: 33363747
DOI: 10.1002/ccr3.3151 -
Annali Italiani Di Chirurgia Sep 2019The primary hyperparathyroidism is a pathological condition that needs frequent surgical treatment. Usually it is encountered due to a parathyroid adenoma, but in rare... (Review)
Review
The primary hyperparathyroidism is a pathological condition that needs frequent surgical treatment. Usually it is encountered due to a parathyroid adenoma, but in rare cases it is configured as structured parathyroid tissue in a rich environment with a bulk of adipose cells. This pathology initially described as Hamartoma of the parathyroid gland and then as parathyroid adenolipoma is rarely encountered and it requires special care from medical staff because of the difficulty in its early diagnosis and also its treatment. We are presenting a case treated by our team and a review of the literature on this topic. KEY WORDS: Hyperparathyroidism, Parathyroid surgery, Parathyroid adenolipoma, Parathyroid hamartoma.
Topics: Adenoma; Humans; Lipoma; Neoplasms, Multiple Primary; Parathyroid Neoplasms
PubMed: 31719215
DOI: No ID Found -
Journal of Cutaneous Pathology Jan 2020Cutaneous spindle cell adenolipoma (SCAL) is a recently described rare variant of lipoma with 11 cases reported to date. Here we report a consultation case of a...
Cutaneous spindle cell adenolipoma (SCAL) is a recently described rare variant of lipoma with 11 cases reported to date. Here we report a consultation case of a 77-year-old male who presented with a nodule on the right nasolabial fold, diagnosed as apocrine fibroadenoma or sebaceous hyperplasia by an outside pathologist. The specimen revealed an ill-defined dermal tumor composed of mature adipocytes, bland spindle cells, ropey collagen, and dilated eccrine and apocrine glands and ducts in a fibromyxoid stroma. The spindle cells were positive for CD34 and negative for S100 protein and SOX10. These findings are consistent with those of cutaneous SCAL. The pathogenesis of this entity is controversial and includes a hamartomatous process, derivation from adipose tissue surrounding eccrine glands, or preexisting glands entrapment within a growing lipoma. In the present case, the glandular component is extensive and includes both eccrine and apocrine differentiation, which has not been previously described and further supports the hamartomatous nature. Awareness of this rare entity is helpful to prevent confusion with other look-alike primary and metastatic cutaneous lesions.
Topics: Adipocytes; Aged; Apocrine Glands; Cell Differentiation; Humans; Lipoma; Male; Neoplasm Proteins; Skin Neoplasms
PubMed: 31329294
DOI: 10.1111/cup.13550 -
Orvosi Hetilap Jun 2018Thyrolipoma or thyroid adenolipoma is an extremely rare form of thyroid adenoma, which also contains mature adipose tissue and follicles covered with fibrous capsule. We...
Thyrolipoma or thyroid adenolipoma is an extremely rare form of thyroid adenoma, which also contains mature adipose tissue and follicles covered with fibrous capsule. We present the case of the growing cervical lesion of a 52-year-old female with diabetes, which was removed during total thyreoidectomy. Autoimmune thyroiditis, bilateral papillary carcinoma and cervical thyrolipoma have been identified by the histopathological examination of the thyroid gland. Orv Hetil. 2018; 159(25): 1024-1032.
Topics: Carcinoma, Papillary; Diabetes Mellitus, Type 2; Female; Humans; Middle Aged; Thyroid Cancer, Papillary; Thyroid Gland; Thyroid Neoplasms; Thyroiditis, Autoimmune
PubMed: 29909657
DOI: 10.1556/650.2018.31017 -
Case Reports in Dermatology 2018Adenolipoma is a relatively recently described lesion representing a rare variant of lipoma in which eccrine glands and ducts are found interspersed amongst mature...
INTRODUCTION
Adenolipoma is a relatively recently described lesion representing a rare variant of lipoma in which eccrine glands and ducts are found interspersed amongst mature adipose tissue. This benign lesion was first described by Hitchcock et al. in 1993 [J Am Acad Dermatol 1993; 29: 82-85]. The next case series was written by Ait-Ourhrouil and Grosshans [Ann Dermatol Venerol 1997; 124: 845-848] in which they deemed adenolipoma a misnomer based on the pathophysiology of the lesion and suggested the name peri-sudoral lipoma instead. According to our knowledge, this case series would be the third in the literature to report cases of adenolipoma in an attempt to increase awareness of this entity.
METHODS
We performed a retrospective review of adenolipoma cases from 2004 to 2014 at our institute.
RESULTS AND CONCLUSIONS
Upon review of all adenolipomas diagnosed at our institute between 2004 and 2014, 11 cases in total were identified. Histologically, these lesions consisted of an admixture of adult-like adipose tissue and scattered eccrine glands and ducts. 4 cases also showed areas of myxoid changes; 2 showed scattered mast cells amongst the adipose tissue, and only 1 showed the presence of apocrine glands in addition to the eccrine glands and ducts. The female to male ratio was 6: 5. The typical age ranged from 41 to 53 years. Adenolipomas were seen arising from various locations including the thighs, gluteal region, lower leg, shoulder, chest, and trunk. The majority of cases were not fully encapsulated and the size varied from 0.7 to 5.8 cm.
PubMed: 29805368
DOI: 10.1159/000488341 -
Journal of Ultrasound Jun 2018Generally, small quantities of adipose tissue is present in the thyroid gland. The adenolipoma of the thyroid gland is considered a rare finding. It consists in a...
Generally, small quantities of adipose tissue is present in the thyroid gland. The adenolipoma of the thyroid gland is considered a rare finding. It consists in a benign, encapsulated neoplasm composed of mature adipose tissue and glandular elements. We report a case of a 71 year-old female patient presenting with swelling of the anterior neck and history of airway obstruction. Ultrasound (US) examination showed a bulky multinodular goiter which caused dislocation and compression of the trachea. The scans performed at the level of the isthmic region showed the presence of a hyperechoic oval formation with a homogeneous echostructure and regular contours; these characteristics suggested the lipomatous nature of the nodule. The patient was subsequently subjected to a Computer Tomography (CT) of the neck for a pre-operative balance of the goitre and to exclude extra-thyroid pathologies. The CT scan confirmed the sonographic findings, and the probable adipose nature of the isthmic formation. After the patient has been subjected to total thyroidectomy and histological examination confirmed the diagnosis of adenolipoma.
Topics: Aged; Diagnosis, Differential; Female; Goiter; Humans; Lipoma; Thyroid Neoplasms; Tomography, X-Ray Computed; Ultrasonography
PubMed: 29374396
DOI: 10.1007/s40477-017-0270-5 -
American Journal of Respiratory and... Feb 2018
Topics: Adenoma; Aged; Argon Plasma Coagulation; Bronchi; Bronchial Neoplasms; Bronchoscopy; Diagnosis, Differential; Female; Humans; Lost to Follow-Up; Tomography, X-Ray Computed
PubMed: 29266963
DOI: 10.1164/rccm.201710-2003IM -
Iranian Journal of Pathology 2016The presence of adipose tissue in the thyroid gland is a rare finding. Thyrolipoma or adenolipoma of the thyroid is a benign, encapsulated lesion of the thyroid composed...
The presence of adipose tissue in the thyroid gland is a rare finding. Thyrolipoma or adenolipoma of the thyroid is a benign, encapsulated lesion of the thyroid composed of variable amounts of fat and glandular elements. This report presents a case of thyrolipoma in a 69-yr-old female presenting with neck swelling and respiratory distress. Differential diagnosis of the fat-containing thyroid lesion is also presented. Differentiation of the condition from similar lesions is necessary for accurate diagnosis of thyrolipoma
PubMed: 28974966
DOI: No ID Found -
The Journal of Dermatology Jul 2017
Topics: Adenoma; Aged, 80 and over; Biomarkers, Tumor; Diagnosis, Differential; Humans; Lipoma; Male; Nose Neoplasms; Skin Neoplasms
PubMed: 28342245
DOI: 10.1111/1346-8138.13826 -
Journal of Clinical and Diagnostic... Jun 2016Breast hamartomas are benign lesions composed of variety of normal breast components arranged in disorganized manner. These are rare and classified as adenolipoma,...
Breast hamartomas are benign lesions composed of variety of normal breast components arranged in disorganized manner. These are rare and classified as adenolipoma, fibrolipoma, adenofibrolipoma, etc. Clinically these present as painless well-circumscribed, mobile lumps of breast. Incidence and etiology remain obscure due to its rarity. These have been described in women in their 40's or 50's. Mammographically they appear non homogenous mass with circumscribed fatty masses. Histologically they appear as circumscribed masses with variable amount of fat, fibrous and glandular tissue. Here we are presenting adenolipoma in 29-year-old woman with review of literature.
PubMed: 27504390
DOI: 10.7860/JCDR/2016/20659.8001