-
European Journal of Psychotraumatology 2024Emerging evidence has linked childhood maltreatment with cardiovascular disease risk; however, the association between childhood maltreatment and cardiac arrhythmias...
Emerging evidence has linked childhood maltreatment with cardiovascular disease risk; however, the association between childhood maltreatment and cardiac arrhythmias remains unclear. Moreover, any genetic predispositions to atrial fibrillation (AF), a common cardiac arrhythmia associated with an elevated risk of stroke, heart failure, and mortality, that modify such associations have been undocumented. To examine the associations between childhood maltreatment and incident arrhythmias, and whether a genetic predisposition to arrhythmias modifies these associations. This prospective analysis included 151,741 participants from the UK Biobank (mean age 55.8 years, 43.4% male). Childhood maltreatment, including five types, was measured using the Childhood Trauma Screener (CTS). Incident arrhythmias (AF, ventricular arrhythmias [VA], and bradyarrhythmia [BA]) were documented through linked hospital admission and death registry. Weighted AF genetic risk score was calculated. Cox proportional hazard models were conducted to test for associations between childhood maltreatment and incident arrhythmias. During a median follow-up of 12.21 years (interquartile range, 11.49-12.90 years), 6,588 AF, 2,093 BA, and 742 VA events occurred. Compared with the absence of childhood maltreatment, having 3-5 types of childhood maltreatment was associated with an increased risk of incident AF (HR, 1.23; 95%CI 1.09-1.37), VA (HR, 1.39; 95%CI 1.03-1.89), and BA (HR, 1.32; 95%CI 1.09-1.61) after adjusting demographic, socioeconomic and lifestyle factors. The associations between cumulative type of childhood maltreatment and the risk of AF (< .001; = .674) and BA (= .007; = .377) demonstrated a linear pattern. There was a gradient association between childhood maltreatment and AF risks across the intermediate and high genetic risk groups (both < .05) but not within the low genetic risk group (= .378), irrespective of non-significant interaction effect (= .204). Childhood maltreatment was associated with higher risks of incident arrhythmias, especially AF and BA. Genetic risk of AF did not modify these associations.
Topics: Humans; Male; Female; Prospective Studies; Arrhythmias, Cardiac; Middle Aged; United Kingdom; Risk Factors; Genetic Predisposition to Disease; Adult; Cohort Studies; Adult Survivors of Child Abuse; Child Abuse
PubMed: 38912597
DOI: 10.1080/20008066.2024.2366055 -
Journal of Child Sexual Abuse Apr 2024Teacher-student sexual misconduct is a serious instance of child sexual abuse that impacts an estimated 10% of students. We tested whether two effects seen in research...
Teacher-student sexual misconduct is a serious instance of child sexual abuse that impacts an estimated 10% of students. We tested whether two effects seen in research about these types of cases replicated across online American adult and undergraduate samples: (1) sympathy toward younger students who experience sexual abuse compared to older students and (2) leniency in cases of female teachers engaging with male students compared to other gender dyads. Participants ( = 525) reviewed a mock teacher-student sexual encounter and then answered questions about their views and case-related outcomes. Student age emerged as the most influential factor across all our variables of interest, where cases with younger students were viewed as more egregious than those involving older students. Incidents involving boys who experienced abuse were perceived as more "normal" than those involving girls. We found some support for the idea that there is leniency toward women teachers, but limited support for a female teacher-male student leniency effect. While these cases were viewed to be more normal and acceptable than other gender dyads, there were no effects on the other dependent variables. Sample type effects were also minimal, as our adult sample viewed the teachers involved to be more responsible and student complainants as more credible versus the undergraduate sample.
Topics: Humans; Female; Male; Students; School Teachers; Child Abuse, Sexual; Adult; Young Adult; Sex Factors; Age Factors; Child; Attitude; Adolescent; Interpersonal Relations
PubMed: 38910435
DOI: 10.1080/10538712.2024.2369285 -
Sante Publique (Vandoeuvre-les-Nancy,... 2024In France, 122 women were killed by their partner or ex-partner in 2021.
INTRODUCTION
In France, 122 women were killed by their partner or ex-partner in 2021.
PURPOSE OF THE RESEARCH
The principal objective of the AVIC-MG study, on women victims of domestic violence and their expectations of their general practitioner, was to observe whether the women in question, who visit specialist facilities for victims of domestic violence, would like to be questioned about domestic violence by their general practitioner (GP). The secondary objective was to describe this population of women and the characteristics of their GP visits during the last twelve months.
RESULTS
The study showed that more than 90 percent of these women had consulted a GP in the last twelve months and 65 percent of the mothers in the group had consulted a GP for their child(ren). The majority of these women (82 percent) wanted the GP to ask them about domestic violence. They had gone to the GP for specific reasons: fatigue, pain, psychological suffering (anxiety, sadness, difficulty sleeping).
CONCLUSION
The majority of women victims of domestic violence would like primary care practitioners to identify the abuse. Tools are available to help GPs with this complex identification, in particular the DECLICVIOLENCE.FR website.
Topics: Humans; Female; Adult; France; Domestic Violence; Middle Aged; General Practitioners; Young Adult; Adolescent
PubMed: 38906814
DOI: No ID Found -
Cyberpsychology, Behavior and Social... Jun 2024Stalking, a widespread and distressing phenomenon, has recently garnered considerable attention. The advent of digital platforms has revolutionized the landscape of...
Stalking, a widespread and distressing phenomenon, has recently garnered considerable attention. The advent of digital platforms has revolutionized the landscape of stalking, presenting new avenues and challenges for research. However, the impact of the coronavirus disease (COVID)-19 pandemic on stalking remains underexplored, despite extensive studies on similar crimes such as intimate partner violence and domestic violence. To address this gap, our study focused on Reddit, a prominent online platform with a diverse user base and open discussion. Through an analysis of posts from the subreddit (https://www.reddit.com/r/Stalking/), we sought to compare the discourse on stalking before and after the COVID-19 pandemic. We found notable shifts in stalking-related posts before and after the COVID-19 pandemic, particularly with the emergence of new topics centered on cyberstalking. We also observed that the experiences of stalking victims have significantly changed following the COVID-19 pandemic. Based on our findings, we discussed the implications for policies to help stalking victims.
PubMed: 38905134
DOI: 10.1089/cyber.2023.0397 -
Annals of the Academy of Medicine,... May 2023COVID-19 restrictions and lockdown measures have led to impact on the mental health and social service delivery, including the rapid adoption of digital solutions to...
INTRODUCTION
COVID-19 restrictions and lockdown measures have led to impact on the mental health and social service delivery, including the rapid adoption of digital solutions to mental healthcare delivery in Singapore. This study aims to rapidly document the quantitative and qualitative impact of the pandemic restrictions on mental health and social services.
METHOD
This descriptive mixed-methods study consisted of a survey arm and a qualitative arm. Providers and clients from eligible mental health organisations and social service agencies were recruited. The respondents completed a survey on changes to their service delivery and the extent of impact of the pandemic on their clients. In-depth interviews were also conducted with representatives of the organisations and clients.
RESULTS
There were 31 organisation representatives to the survey, while 16 providers and 3 clients participated in the in-depth interviews. In the survey arm, all representatives reported pivoting to remote means of delivering care during the lockdown. An increase in new client referrals and more domestic violence were reported from primary and community health partners respondents who made up 55.5% of health partners respondents. Three distinct response themes were recorded in the in-depth interviews: impact on clients, impact on service provision and impact on mental health landscape.
CONCLUSION
Two key findings are distilled: (1) mental health and social services have been challenged to meet the evolving demands brought about by the pandemic; (2) more societal attention is needed on mental health and social services. The findings indicate a necessary need for extensive studies on COVID-19 that can inform policies to build a more pandemic-resilient nation.
Topics: Humans; Singapore; COVID-19; Mental Health Services; Social Work; Qualitative Research; Mental Health; Surveys and Questionnaires; SARS-CoV-2; Female; Male; Pandemics; Adult
PubMed: 38904521
DOI: 10.47102/annals-acadmedsg.2022332 -
Cureus May 2024Introduction Domestic violence (DV) in the form of verbal abuse is very common among women, especially pregnant women, posing as a serious public health issue that...
Introduction Domestic violence (DV) in the form of verbal abuse is very common among women, especially pregnant women, posing as a serious public health issue that could lead to complications in pregnancy and threaten maternal and fetal outcomes. Studies have determined that domestic verbal abuse (DVA) in pregnancy was more common in women less than 25 years of age as well as in those with low education levels. This study determined the overall prevalence of verbal abuse in pregnant women, in a semi-urban population and is unique in that the verbal abuse in pregnant women with a previous girl child was also determined. This study helps healthcare providers identify the potential causes of DVA in pregnancy and provide timely interventions in the form of counseling for pregnant women and families. Objective This observational study was carried out to assess the prevalence of DVA among pregnant women, to determine the trimester of occurrence of DVA among pregnant women, and to explore the associations of DVA with age, employment status, parity gestational age, and birth weight. Materials and methods This was a six-month hospital-based observational study conducted at Dr D. Y. Patil Medical College's in-patient department (IPD) of Obstetrics and Gynecology in Pimpri, Pune. Consent was obtained from 200 pregnant women who received admission for delivery and provided a validated modified copy of a DV assessment screening questionnaire. A statistical analysis was performed using GraphPad Prism 10. A Chi-square test was employed wherever required, and a p-value of less than 0.05 was considered significant. Results The study included 200 pregnant women, who were admitted to the hospital for delivery. The prevalence of DV in the form of verbal abuse was noted to be 74 out of 200 (37%). The working status of the woman showed an influence on DVA. There was also a significant increase in verbal abuse (68%) among the age group between 18 and 23 years. The previous delivery of a female child also had a significant impact on DVA, which turned out to be more prevalent, particularly if two female children were born previously (80%). The study also noted higher rates of preterm deliveries in pregnant women with DVA being 57%. Conclusion The study demonstrates that women, even in modern times, experience DVA during pregnancy, especially among the younger age group. It has also been found that it is more common among women who are financially dependent due to maternal unemployment. As a result, there is a need to routinely screen pregnant women for DVA to avoid potentially detrimental pregnancy outcomes and to prevent ongoing abuse.
PubMed: 38903275
DOI: 10.7759/cureus.60740 -
International Ophthalmology Jun 2024Forensic science has made a lot of progress in the medical field, but still ocular signs are not so well known to forensic scientists, whereas ocular signs play a very... (Review)
Review
Forensic science has made a lot of progress in the medical field, but still ocular signs are not so well known to forensic scientists, whereas ocular signs play a very important role in forensic science. The major goal of this study to describe the importance of eye related clues in forensic science to solve the crime scenes and know the actual cause of death for the conviction of the criminals and save an innocent persons. Narrative review was done to review the articles available on the PubMed, Google Scholar, Research Gate, Web of Science and Medline related to the forensic optometry about the various methods of identification and strategies to deal with the forensic cases. The review covered studies that focused on interventions for forensic optometry and eye-related clues to the current study target. Twenty-seven of the 54 studies that met the inclusion criteria yielded good results, and all examined the significance of eye-related clues in forensic optometry. Peer reviewed articles/studies were referred to ascertain the eye related clues in the forensic science. Some authors suggest that eye related clues are very important aspects towards the forensic science and done the clinical research on that aspects. Criminal cases, domestic abuse and sexual assault affect people of all socioeconomic backgrounds. As a result, these traits would be highly valuable in determining the way of death and the chronological history of events leading up to a crime.
Topics: Humans; Optometry; Forensic Sciences; Sex Offenses; Domestic Violence
PubMed: 38902435
DOI: 10.1007/s10792-024-03202-w -
Child Maltreatment Jun 2024Child maltreatment (CM) is associated with negative health outcomes in adulthood, including deliberate self-harm (DSH), suicidal behaviours, and victimisation. It is...
Child maltreatment (CM) is associated with negative health outcomes in adulthood, including deliberate self-harm (DSH), suicidal behaviours, and victimisation. It is unknown if associations extend to emergency department (ED) presentations for non-DSH related injuries. Birth cohort study data was linked to administrative health data, including ED presentations for non DSH related injuries and agency-reported and substantiated notifications for CM. Adjusted analyses ( = 6087) showed that any type of agency-reported notification for CM was significantly associated with increased odds of ED presentation for injuries (aOR = 1.57; 95% CI 1.32-1.87). In moderation analyses, women yielded significantly higher odds of notified and substantiated physical abuse, substantiated emotional abuse, and being subject to more than one type of substantiated abuse than males. ED presentations for injuries could be a proxy for risky behaviours, disguised DSH/suicidal behaviours, or physical abuse. The consistent findings in women may point to victimisation via interpersonal violence.
PubMed: 38901464
DOI: 10.1177/10775595241264009 -
Journal of Psychosomatic Research Aug 2024Childhood maltreatment (CM) is linked to self-reported liver disease in adulthood. However, specific diagnostic entities, e.g., metabolic dysfunction-associated...
BACKGROUND AND AIMS
Childhood maltreatment (CM) is linked to self-reported liver disease in adulthood. However, specific diagnostic entities, e.g., metabolic dysfunction-associated steatotic liver disease (MASLD) as the most frequent chronic liver disease, and sex-differences have previously not been considered.
METHODS
Cross-sectional analyses were conducted in 4188 adults from a population-based cohort in Northeastern Germany after excluding individuals with excessive alcohol consumption, cirrhosis, or chronic viral hepatitis. CM-exposure was assessed using the Childhood Trauma Questionnaire (CTQ). Liver-related outcomes included serologic liver enzymes, fibrosis-4 score (FIB-4) and, in 1863 subjects who underwent magnetic resonance imaging examination, liver fat content. Sex-stratified linear regression and logistic regression models predicting liver-related outcomes and risk for MASLD, respectively, from overall CTQ scores were adjusted for age, school education, alcohol consumption, and waist circumference. Exploratory analyses investigated effects of CTQ-subscales on liver-related outcomes and risk for MASLD.
RESULTS
In both sexes, overall CM-exposure was associated with higher levels of serum aspartate aminotransferase and FIB-4 score. In men, effects were mainly driven by physical abuse, and in women by emotional neglect. Only in men, overall CM-exposure (β = 0.70, 95%-CI 0.26-1.13, p = 0.002) and four CTQ-subscales were associated with greater liver fat content, and physical abuse (aOR = 1.22, 95%-CI 1.02-1.46, p = 0.034) and physical neglect (aOR = 1.25, 95%-CI 1.04-1.49, p = 0.015) were associated with higher risk for MASLD.
CONCLUSIONS
These results suggest sex differences in the association between CM and objective serum and imaging markers of MASLD in adulthood. For men especially, a history of CM-exposure may increase risk of developing MASLD in adulthood.
Topics: Humans; Male; Female; Cross-Sectional Studies; Middle Aged; Adult; Germany; Sex Factors; Fatty Liver; Child Abuse; Adverse Childhood Experiences; Adult Survivors of Child Abuse; Risk Factors; Aged
PubMed: 38896985
DOI: 10.1016/j.jpsychores.2024.111829 -
The Journal of Headache and Pain Jun 2024Large conductance calcium-activated potassium (BK) channels have been implicated in the neurobiological underpinnings of migraine. Considering the clinical... (Randomized Controlled Trial)
Randomized Controlled Trial
BACKGROUND
Large conductance calcium-activated potassium (BK) channels have been implicated in the neurobiological underpinnings of migraine. Considering the clinical similarities between migraine and persistent post-traumatic headache (PPTH), we aimed to examine whether MaxiPost (a BK channel opener) could induce migraine-like headache in persons with PPTH.
METHODS
This is a randomized double-blind, placebo-controlled, two-way crossover study from September 2023 to December 2023. Eligible participants were adults with PPTH after mild traumatic brain injury who reported having no personal history of migraine. The randomized participants received a single dose of either MaxiPost (0.05 mg/min) or placebo (isotonic saline) that was infused intravenously over 20 minutes. The two experiment sessions were scheduled at least one week apart to avoid potential carryover effects. The primary endpoint was the induction of migraine-like headache after MaxiPost as compared to placebo within 12 hours of drug administration. The secondary endpoint was the area under the curve (AUC) values for headache intensity scores between MaxiPost and placebo over the same 12-hour observation period.
RESULTS
Twenty-one adult participants (comprising 14 females and 7 males) with PPTH were enrolled and completed both experiment sessions. The proportion of participants who developed migraine-like headache was 11 (52%) of 21 participants after MaxiPost infusion, in contrast to four (19%) participants following placebo (P = .02). Furthermore, the median headache intensity scores, represented by AUC values, were higher following MaxiPost than after placebo (P < .001).
CONCLUSIONS
Our results indicate that BK channel opening can elicit migraine-like headache in persons with PPTH. Thus, pharmacologic blockade of BK channels might present a novel avenue for drug discovery. Additional investigations are nonetheless needed to confirm these insights and explore the therapeutic prospects of BK channel blockers in managing PPTH.
GOV IDENTIFIER
NCT05378074.
Topics: Humans; Female; Male; Adult; Double-Blind Method; Cross-Over Studies; Post-Traumatic Headache; Migraine Disorders; Middle Aged; Brain Concussion; Large-Conductance Calcium-Activated Potassium Channel alpha Subunits; Young Adult; Large-Conductance Calcium-Activated Potassium Channels
PubMed: 38890563
DOI: 10.1186/s10194-024-01808-0