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Heliyon Jun 2024Ergonomic risk factors are a prominent cause of fatality and severe injuries in building constructions. Hence, this study applies a Structural Equation Modeling (SEM)...
Structural equation modeling approach for the analysis of ergonomics risk factors and occupational injuries among building construction workers in Bahir Dar City-Ethiopia.
Ergonomic risk factors are a prominent cause of fatality and severe injuries in building constructions. Hence, this study applies a Structural Equation Modeling (SEM) approach to analyze ergonomics risk factors and occupational injuries among building construction workers in Bahir Dar City, Ethiopia. The results indicate significant relationships between ergonomics risk factors and the prevalence of occupational injuries. This study's findings contribute to the understanding of occupational health and safety in the construction industry, highlighting the need for targeted interventions. A cross-sectional study has been carried out, where data was collected through direct observations and standardized pretested questionnaires. The study recruited 220 participants in the construction industry. The data was analyzed using AMOS to study the direct and indirect effects of the identified variable. SEM has shown that the magnitude of the prevalence of occupational injury was 65.2 %. The results also revealed that the mostly affected body parts were lower arm, lower leg, hand, toe, and knee. Carpenter & roofers, plasterer and daily labors & other helpers were highly injury subjected occupations in respective order. The six leading significant risk factors were, do not tie belt at scaffold, falling stairways & ladders, exposure hazardous substances, tools & machinery, electricity (electric power accidents), repetitive tasks, the layout didn't consider health & safety aspects in the site, and do not provide safety orientation for new workers engaging the job. Employees are mostly affected on their lower body parts which needs more focus to prevent it, especially carpenter & roofers, plasterer and daily labors. Also the findings show that 50 % of respondents agree that the higher priority for safety and health management practices should be given to finishing part of the construction followed by excavation and earth work, masonry, and electrical installations. Therefore, it is recommended that the contractors must focus more on the finishing phase.
PubMed: 38933936
DOI: 10.1016/j.heliyon.2024.e32234 -
Frontiers in Public Health 2024Pollution has emerged as a significant threat to humanity, necessitating a thorough evaluation of its impacts. As a result, various methods for human biomonitoring have... (Review)
Review
INTRODUCTION
Pollution has emerged as a significant threat to humanity, necessitating a thorough evaluation of its impacts. As a result, various methods for human biomonitoring have been proposed as vital tools for assessing, managing, and mitigating exposure risks. Among these methods, urine stands out as the most commonly analyzed biological sample and the primary matrix for biomonitoring studies.
OBJECTIVES
This review concentrates on exploring the literature concerning residual pesticide determination in urine, utilizing liquid and gas chromatography coupled with mass spectrometry, and its practical applications.
METHOD
The examination focused on methods developed since 2010. Additionally, applications reported between 2015 and 2022 were thoroughly reviewed, utilizing Web of Science as a primary resource.
SYNTHESIS
Recent advancements in chromatography-mass spectrometry technology have significantly enhanced the development of multi-residue methods. These determinations are now capable of simultaneously detecting numerous pesticide residues from various chemical and use classes. Furthermore, these methods encompass analytes from a variety of environmental contaminants, offering a comprehensive approach to biomonitoring. These methodologies have been employed across diverse perspectives, including toxicological studies, assessing pesticide exposure in the general population, occupational exposure among farmers, pest control workers, horticulturists, and florists, as well as investigating consequences during pregnancy and childhood, neurodevelopmental impacts, and reproductive disorders.
FUTURE DIRECTIONS
Such strategies were essential in examining the health risks associated with exposure to complex mixtures, including pesticides and other relevant compounds, thereby painting a broader and more accurate picture of human exposure. Moreover, the implementation of integrated strategies, involving international research initiatives and biomonitoring programs, is crucial to optimize resource utilization, enhancing efficiency in health risk assessment.
Topics: Humans; Pesticide Residues; Biological Monitoring; Gas Chromatography-Mass Spectrometry; Mass Spectrometry; Environmental Exposure; Chromatography, Liquid
PubMed: 38932775
DOI: 10.3389/fpubh.2024.1336014 -
Viruses May 2024The presence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in wastewater has been reported in several studies and similar research can be used as a...
Distribution of SARS-CoV-2 Genomes in Wastewaters and the Associated Potential Infection Risk for Plant Workers in Typical Urban and Peri-Urban Communities of the Buffalo City Region, South Africa.
The presence of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in wastewater has been reported in several studies and similar research can be used as a proxy for an early warning of potential Coronavirus disease 2019 (COVID-19) outbreaks. This study focused on profiling the incidence of SARS-CoV-2 genomes in wastewater samples obtained from facilities located in the Buffalo City Municipality. Raw samples were collected weekly using the grab technique for a period of 48 weeks. Ribonucleic acids were extracted from the samples, using the QIAGEN Powersoil Total RNA Extraction kit, and extracted RNA samples were further profiled for the presence of SARS-CoV-2 genomes using Quantitative Real-Time Polymerase Chain Reaction (qRT-PCR) technique. Furthermore, various environmental matrices were utilized to estimate the potential health risk to plant operators associated with exposure to SARS-CoV-2 viral particles using the quantitative microbiological risk assessment (QMRA) model. Our findings revealed the prevalence of SARS-CoV-2 genomes with concentrations that ranged from 0.22 × 103 to 17.60 × 103 genome copies per milliliter (GC/mL). Different exposure scenarios were employed for the QMRA model, and the findings indicate a probability of infection (P(i)) ranging from 0.93% to 37.81% across the study sites. Similarly, the P(i) was highly significant ( < 0.001) for the 20 mL volumetric intake as compared to other volumetric intake scenarios, and high P(i) was also observed in spring, autumn, and winter for all WWTPs. The P(i) was significantly different ( < 0.05) with respect to the different seasons and with respect to different volume scenarios.
Topics: Wastewater; SARS-CoV-2; South Africa; COVID-19; Humans; Genome, Viral; Risk Assessment; RNA, Viral; Occupational Exposure; Cities
PubMed: 38932163
DOI: 10.3390/v16060871 -
Microorganisms Jun 2024Wastewater treatment plants (WWTPs) are crucial in the scope of European Commission circular economy implementation. However, bioaerosol production may be a hazard for... (Review)
Review
BACKGROUND
Wastewater treatment plants (WWTPs) are crucial in the scope of European Commission circular economy implementation. However, bioaerosol production may be a hazard for occupational and public health. A scoping review regarding microbial contamination exposure assessment in WWTPs was performed.
METHODS
This study was performed through PRISMA methodology in PubMed, Scopus and Web of Science.
RESULTS
28 papers were selected for data extraction. The WWTPs' most common sampled sites are the aeration tank (42.86%), sludge dewatering basin (21.43%) and grit chamber. Air sampling is the preferred sampling technique and culture-based methods were the most frequently employed assays. sp. (21.43%), sp. (7.14%), sp. (3.57%), sp. (7.14%) and sp. (3.57%) were the most isolated bacteria and sp. (17.86%), sp. (10.71%) and sp. (10.71%) dominated the fungal presence.
CONCLUSIONS
This study allowed the identification of the following needs: (a) common protocol from the field (sampling campaign) to the lab (assays to employ); (b) standardized contextual information to be retrieved allowing a proper risk control and management; (c) the selection of the most suitable microbial targets to serve as indicators of harmful microbial exposure. Filling these gaps with further studies will help to provide robust science to policy makers and stakeholders.
PubMed: 38930526
DOI: 10.3390/microorganisms12061144 -
Antioxidants (Basel, Switzerland) May 2024Nanomaterials (NMs) are in high demand for a wide range of practical applications; however, comprehensively understanding the toxicity of these materials is a complex...
Nanomaterials (NMs) are in high demand for a wide range of practical applications; however, comprehensively understanding the toxicity of these materials is a complex challenge, due to the limited availability of epidemiological evidence on the human health effects arising from workplace exposures. The aim of this work is to assess whether and how urinary metal concentrations could be reliable and useful in NM biomonitoring. In the framework of "NanoExplore Project" [EU LIFE17 Grant ENV/GR/000285], 43 not-exposed subjects and 40 exposed workers were recruited to measure exposure to NMs (PCN and LDSA) in the proximity of the workstations and biological biomarkers (urinary metal concentrations-Aluminum (Al), Silica (Si), Titanium (Ti), and Chromium (Cr); urinary OS biomarkers-TAP, Isop, and MDA). The results showed that Si and Ti were directly associated with NM exposure (both PCN and LDSA), as well as with OS biomarkers, especially in exposed workers. Moreover, the mediation analyses showed that Si could account for about 2.8% in the relationship between LDSA and OS biomarkers, possibly by decreasing OS antioxidant defenses in exposed people. In conclusion, our study provides evidence that occupational exposure to mixtures containing NMs can represent an underestimated hazard for exposed people, increasing the body burden and the oxidative balance.
PubMed: 38929117
DOI: 10.3390/antiox13060676 -
International Journal of Environmental... Jun 2024The emerging concern about chemicals in electronic cigarettes, even those without nicotine, demands the development of advanced criteria for their exposure and risk...
The emerging concern about chemicals in electronic cigarettes, even those without nicotine, demands the development of advanced criteria for their exposure and risk assessment. This study aims to highlight the sensitivity of lung nuclear receptors (NRs) to electronic cigarette e-liquids, independent of nicotine presence, and the influence of the sex variable on these effects. Adult male and female C57BL/6J mice were exposed to electronic cigarettes with 0%, 3%, and 6% nicotine daily (70 mL, 3.3 s, 1 puff per min/30 min) for 14 days, using the inExpose full body chamber (SCIREQ). Following exposure, lung tissues were harvested, and RNA extracted. The expression of 84 NRs was determined using the RT profiler mRNA array (Qiagen). Results exhibit a high sensitivity to e-liquid exposure irrespective of the presence of nicotine, with differential expression of NRs, including one (females) and twenty-four (males) in 0% nicotine groups compared to non-exposed control mice. However, nicotine-dependent results were also significant with seven NRs (females), fifty-three NRs (males) in 3% and twenty-three NRs (female) twenty-nine NRs (male) in 6% nicotine groups, compared to 0% nicotine mice. Sex-specific changes were significant, but sex-related differences were not observed. The study provides a strong rationale for further investigation.
Topics: Animals; Female; Male; Electronic Nicotine Delivery Systems; Mice, Inbred C57BL; Pilot Projects; Mice; Lung; Aerosols; Nicotine; Receptors, Cytoplasmic and Nuclear; Sex Factors
PubMed: 38929056
DOI: 10.3390/ijerph21060810 -
International Journal of Environmental... Jun 2024Metal workshops are workplaces with the substantial production of particulate matter (PM) with high metal content, which poses a significant health risk to workers. The...
Metal workshops are workplaces with the substantial production of particulate matter (PM) with high metal content, which poses a significant health risk to workers. The PM produced by different metal processing techniques differs considerably in its elemental composition and size distribution and therefore poses different health risks. In some previous studies, the pollution sources were isolated under controlled conditions, while, in this study, we present a valuable alternative to characterize the pollution sources that can be applied to real working environments. Fine PM was sampled in five units (partially specializing in different techniques) of the same workshop. A total of 53 samples were collected with a temporal resolution of 30 min and 1 h. The mass concentrations were determined gravimetrically, and the elemental analysis, in which the concentrations of 14 elements were determined, was carried out using the X-ray fluorescence technique. Five sources of pollution were identified: background, steel grinding, metal active gas welding, tungsten inert gas welding, and machining. The sources were identified by positive matrix factorization, a statistical method for source apportionment. The identified sources corresponded well with the work activities in the workshop and with the actual sources described in previous studies. It is shown that positive matrix factorization can be a valuable tool for the identification and characterization of indoor sources.
Topics: Particulate Matter; Environmental Monitoring; Metals; Metallurgy; Occupational Exposure; Air Pollutants, Occupational; Air Pollution, Indoor; Spectrometry, X-Ray Emission
PubMed: 38929014
DOI: 10.3390/ijerph21060768 -
International Journal of Environmental... Jun 2024Studies examining occupational exposures and cancer risk frequently report mixed findings; it is thus imperative for researchers to synthesize study results and identify...
Studies examining occupational exposures and cancer risk frequently report mixed findings; it is thus imperative for researchers to synthesize study results and identify any potential sources that explain such variabilities in study findings. However, when synthesizing study results using meta-analytic techniques, researchers often encounter a number of practical and methodological challenges. These challenges include (1) an incomparability of effect size measures due to large variations in research methodology; (2) a violation of the independence assumption for meta-analysis; (3) a violation of the normality assumption of effect size measures; and (4) a variation in cancer definitions across studies and changes in coding standards over time. In this paper, we first demonstrate these challenges by providing examples from a real dataset collected for a large meta-analysis project that synthesizes cancer mortality and incidence rates among firefighters. We summarize how each of these challenges has been handled in our meta-analysis. We conclude this paper by providing practical guidelines for handling challenges when synthesizing study findings from occupational cancer literature.
Topics: Humans; Neoplasms; Occupational Exposure; Meta-Analysis as Topic; Occupational Diseases; Firefighters; Research Design; Incidence
PubMed: 38928988
DOI: 10.3390/ijerph21060742 -
International Journal of Environmental... May 2024Vaccination is a highly effective tool for controlling infectious diseases, particularly in populations at high risk of contagion due to clinical conditions or...
BACKGROUND
Vaccination is a highly effective tool for controlling infectious diseases, particularly in populations at high risk of contagion due to clinical conditions or occupational exposure, such as healthcare workers. The purpose of this study is to present the open day event that marked the beginning of the influenza and anti-COVID-19 vaccination campaign in the Lombardy region and to describe the experience of an Istituto di Ricovero e Cura a Carattere Scientifico in Milan.
METHODS
During the vaccination open day, eligible individuals received free vaccinations for influenza, COVID-19, pneumococcal disease, and shingles, as provided by the Lombardy Agenzia per la Tutela della Salute. In celebration of the centenary of the Università degli Studi di Milano, the Fondazione Ca'Granda Ospedale Policlinico, a contracted hospital of the university, created a special electronic diary for a total of 150 individuals, equally divided between children aged 2-6, pregnant women, and university staff.
RESULTS
At the regional level, a total of 6634 influenza vaccines, 2055 anti-COVID-19 vaccines, 108 anti-pneumococcal vaccines, and 37 anti-zoster vaccines were administered. A total of 3134 (47.3%) influenza vaccines, 1151 (56%) anti-COVID-19 vaccines, and 77 (62%) anti-pneumococcal vaccines, were given to individuals aged 60-79. No differences were observed between the total number of male and female vaccinees (1017 and 1038, respectively), who received the anti-COVID-19 vaccine. At the Policlinico Foundation, out of 150 available booking slots, 154 vaccines were administered, including 117 influenza vaccines.
CONCLUSIONS
The establishment of vaccine open days is a beneficial way to increase vaccine compliance. Co-administration of little-known vaccinations outside of healthcare settings could also be a useful tool.
Topics: Italy; Humans; Cross-Sectional Studies; Female; COVID-19; Vaccination; COVID-19 Vaccines; Male; Influenza Vaccines; Adult; Middle Aged; Child; Child, Preschool; Pneumococcal Vaccines; Pregnancy; Aged
PubMed: 38928932
DOI: 10.3390/ijerph21060685 -
International Journal of Environmental... May 2024Engineered stone (ES) is a popular building product, due to its architectural versatility and generally lower cost. However, the fabrication of organic resin-based ES... (Review)
Review
Engineered stone (ES) is a popular building product, due to its architectural versatility and generally lower cost. However, the fabrication of organic resin-based ES kitchen benchtops from slabs has been associated with alarming rates of silicosis among workers. In 2024, fifteen years after the first reported ES-related cases in the world, Australia became the first country to ban the use and importation of ES. A range of interacting factors are relevant for ES-associated silicosis, including ES material composition, characteristics of dust exposure and lung cell-particle response. In turn, these are influenced by consumer demand, work practices, particle size and chemistry, dust control measures, industry regulation and worker-related characteristics. This literature review provides an evidence synthesis using a narrative approach, with the themes of product, exposure and host. Exposure pathways and pathogenesis are explored. Apart from crystalline silica content, consideration is given to non-siliceous ES components such as resins and metals that may modify chemical interactions and disease risk. Preventive effort can be aligned with each theme and associated evidence.
Topics: Silicosis; Humans; Occupational Exposure; Construction Materials; Dust
PubMed: 38928930
DOI: 10.3390/ijerph21060683