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Polymers Jun 2024It is difficult for the existing Burgers model to accurately depict the off-axis cyclic drawing process of woven coatings. In this paper, the mechanical deformation of...
It is difficult for the existing Burgers model to accurately depict the off-axis cyclic drawing process of woven coatings. In this paper, the mechanical deformation of woven PVC (polyvinyl chloride)-coated film at different temperatures is investigated. One-dimensional (1D) and two-dimensional (2D) constitutive models were established to characterize cyclic deformation processes. The 1D model is an improved Burgers model. The effects of the time dependence of the viscosity coefficient and the ratio of elastic to viscous deformation are considered simultaneously. The accuracy of the 1D model for predicting the cyclic nonlinear deformation at different temperatures and loading rates is improved. The 2D model is a nonlinear orthotropic model using polynomials. On the basis of the single-objective genetic algorithm, the inverse algorithm is used to obtain the shear polynomial coefficients in the tension phase and the shear modulus in the unloading phase, which circumvents performing the difficult shear test. UMAT subroutines of off-axis stretching and off-axis cyclic stretching are written separately. The intelligent inverse algorithm program consists of a single-objective genetic algorithm program, a finite element parametric modelling program, and a UMAT subroutine. The simulation results are compared with the off-axis cyclic tensile test data to validate the effectiveness and accuracy of the proposed 2D model for the analysis of the woven PVC-coated films in the tension-shear coupling state.
PubMed: 38931973
DOI: 10.3390/polym16121623 -
Pharmaceutics May 2024The increasing prevalence of diabetic wounds presents a significant challenge due to the difficulty of natural healing and various obstacles. (DB) and (AT) are well...
The increasing prevalence of diabetic wounds presents a significant challenge due to the difficulty of natural healing and various obstacles. (DB) and (AT) are well recognized for their potent healing abilities, which include potent antibacterial and anti-inflammatory activities. In this study, electrospun nanofibers (NFs) based on polyvinyl pyrrolidone (PVP) were co-loaded with both DB and AT, aiming to magnify their efficacy as wound-dressing applications for diabetic wound healing. The evaluation of these NFs as wound dressings was conducted using a streptozotocin-induced diabetic rat model. Electrospun NFs were prepared using the electrospinning of the PVP polymer, resulting in nanofibers with consistent, smooth surfaces. The loading capacity (LC) of AT and DB into NFs was 64.1 and 70.4 µg/mg, respectively, while in the co-loaded NFs, LC was 49.6 for AT and 57.2 µg/mg for DB. In addition, X-ray diffraction (XRD) revealed that DB and AT were amorphously dispersed within the NFs. The loaded NFs showed a dissolution time of 30 s in PBS (pH 7.4), which facilitated the release of AT and DB (25-38% after 10 min), followed by a complete release achieved after 180 min. The antibacterial evaluation demonstrated that the DB-AT mixture had potent activity against () and (). Along with that, the DB-AT NFs showed effective growth inhibition for both and compared to the control NFs. Moreover, wound healing was evaluated in vivo in diabetic Wistar rats over 14 days. The results revealed that the DB-AT NFs improved wound healing within 14 days significantly compared to the other groups. These results highlight the potential application of the developed DB-AT NFs in wound healing management, particularly in diabetic wounds.
PubMed: 38931828
DOI: 10.3390/pharmaceutics16060704 -
Molecules (Basel, Switzerland) Jun 2024The preparation and application of the composite material "crosslinked polyvinyl alcohol-magnetite" as a sensitive matrix for use in digital colorimetry and optical...
The preparation and application of the composite material "crosslinked polyvinyl alcohol-magnetite" as a sensitive matrix for use in digital colorimetry and optical micrometry methods are discussed. The material was synthesized in the form of spherical granules (for micrometry) and thin films (for digital colorimetry). The obtained composites were characterized by the registration of magnetization curves. It was shown that the amount of grown FeO particles in the polymer gel is in linear dependence with the iron salt concentrations in the impregnating solutions. The composite granules were applied to determining monosaccharides using optical micrometry. The optimal pH value for the total amount of monosaccharides' determination was 8.6. The study of the analytical response of composite granules and films performed with a low limit of detection (7.9 mmol/dm) of both glucose and fructose and a possibility of the control of high alcohol contention in water media. The granules were used to determine the total carbohydrate content in samples of natural honey and syrups with high fructose contents, while the films were used to control the alcohol content in hand antiseptics. The results obtained are in good agreement with the data provided by the manufacturers.
PubMed: 38930858
DOI: 10.3390/molecules29122794 -
Materials (Basel, Switzerland) Jun 2024In this research, a direct-write 3D-printing method was utilized for the fabrication of inter-digitized solid oxide fuel cells (SOFCs) using ceramic materials. The...
In this research, a direct-write 3D-printing method was utilized for the fabrication of inter-digitized solid oxide fuel cells (SOFCs) using ceramic materials. The cathode electrode was fabricated using the LSCF (LaSrFeCoO) slurry loading and the Polyvinyl butyral (PVB) binder. The rheological parameters of slurries with varying LSCF slurry loading and PVB binder concentration were evaluated to determine their effect on the cathode trace performance in terms of microstructure, size, and resistance. Additionally, the dimensional shrinkage of LSCF lines after sintering was investigated to realize their influence on cathode line width and height. Moreover, the effect of the direct-write process parameters such as pressure, distance between the nozzle and substrate, and speed on the cathode line dimensions and resistance was evaluated. LSCF slurry with 50% solid loading, 12% binder, and 0.2% dispersant concentration was determined to be the optimal value for the fabrication of SOFCs using the direct-write method. The direct-write process parameters, in addition to the binder and LSCF slurry concentration ratios, had a considerable impact on the microstructure of cathode lines. Based on ANOVA findings, pressure and distance had significant effects on the cathode electrode resistance. An increase in the distance between the nozzle and substrate, speed, or extrusion pressure of the direct writing process increased the resistance of the cathode lines. These findings add to the ongoing effort to refine SOFC fabrication techniques, opening the avenues for advanced performance and efficiency of SOFCs in energy applications.
PubMed: 38930192
DOI: 10.3390/ma17122822 -
International Journal of Molecular... Jun 2024Bioactive compounds that can be recovered by the solid wastes of the olive oil sector, such as polyphenols, are known for their significant antioxidant and antimicrobial...
Bioactive compounds that can be recovered by the solid wastes of the olive oil sector, such as polyphenols, are known for their significant antioxidant and antimicrobial activities with potential application in nutraceutical, cosmetic, and food industries. Given that industrial demands are growing, and the polyphenol market value is ever increasing, a systematic study on the recovery of natural antioxidant compounds from olive pomace using ultrasound-assisted extraction (UAE) was conducted. Single-factor parameters, i.e., the extraction solvent, time, and solid-to-liquid ratio, were investigated evaluating the total phenolic content (TPC) recovery and the antioxidant activity of the final extract. The acetone-water system (50% /, 20 min, 1:20 g mL) exhibited the highest total phenolic content recovery (168.8 ± 5.5 mg GAE per g of dry extract). The olive pomace extract (OPE) was further assessed for its antioxidant and antibacterial activities. In DPPH, ABTS, and CUPRAC, OPE exhibited an antioxidant capacity of 413.6 ± 1.9, 162.72 ± 3.36 and 384.9 ± 7.86 mg TE per g of dry extract, respectively. The antibacterial study showed that OPE attained a minimum inhibitory activity (MIC) of 2.5 mg mL against and 10 mg mL against . Hydroxytyrosol and tyrosol were identified as the major phenolic compounds of OPE. Furthermore, active chitosan-polyvinyl alcohol (CHT/PVA) films were prepared using different OPE loadings (0.01-0.1%, ). OPE-enriched films showed a dose-dependent antiradical scavenging activity reaching 85.7 ± 4.6% (ABTS) and inhibition growth up to 81% against compared to the control film. Increased UV light barrier ability was also observed for the films containing OPE. These results indicate that OPE is a valuable source of phenolic compounds with promising biological activities that can be exploited for developing multifunctional food packaging materials.
Topics: Olea; Antioxidants; Plant Extracts; Anti-Bacterial Agents; Phenols; Food Packaging; Polyphenols; Ultrasonic Waves; Microbial Sensitivity Tests
PubMed: 38928246
DOI: 10.3390/ijms25126541 -
BMC Chemistry Jun 2024The antibacterial characteristics of graphene oxide (GO-SB) nano-sheets generated by charring sugarcane bagasse (SB) are described in this study. The antibacterial...
Fluffy-like amphiphilic graphene oxide and its effects on improving the antibacterial activity and thermal outstanding of ethyl cellulose /polyvinyl alcohol hydrogel film.
The antibacterial characteristics of graphene oxide (GO-SB) nano-sheets generated by charring sugarcane bagasse (SB) are described in this study. The antibacterial capability of GO-SB was improved when it was grafted with ethyl cellulose (EC) and polyvinyl alcohol (PVA) to form GO-SB/EC/PVA hydrogels. Characterization of GO-SB nanosheets and GO-SB/EC/PVA hydrogels was accomplished by using FTIR, SEM, XRD, and thermal studies. The antimicrobial activity was carried out against Gram positive bacteria [Micrococcus leutus & Staphylococcus aureus], Gram negative bacteria [Escherichia coli, Pseudomonas aeruginosa] and pathogenic fungal yeast [Candida albicans] applying the disc diffusion method. The disc diffusion method results showed that the improved GO-SB/EC/PVA exhibited a reasonable level of antimicrobial capability against Micrococcus leutus, demonstrating that the antimicrobial improvement of GO-SB was more effective in the GO-SB/EC/PVA hydrogels by increasing the inhibition zone of Gram-positive bacteria, Micrococcus leutus from (13.0 to 16.0 mm).
PubMed: 38926782
DOI: 10.1186/s13065-024-01221-3 -
International Journal of Biological... Jun 2024Biodegradable and biocompatible polymer-based nanoparticles (NPs) hold great promise for various industries. We report the first development of composite NPs consisting...
Biodegradable and biocompatible polymer-based nanoparticles (NPs) hold great promise for various industries. We report the first development of composite NPs consisting of starch (St) and polyvinyl alcohol (PVA) using the nanoprecipitation technique with ethanol as an antisolvent. We varied the St:PVA ratios in the precursor solutions to evaluate their impact on the structure and properties of the composite NPs. The ratios used were 4:1, 1:1, and 1:4. Characterization by X-ray diffraction, differential scanning calorimetry, and thermogravimetric analysis revealed distinct XRD and TGA patterns for the composite St/PVANPs compared to their corresponding physical blends. This indicated the presence of mixed St/PVA crystallites within their structures. Additionally, the crystallinity of St/PVANPs increased with rising St content. Dynamic light scattering and scanning electron microscopy showed that nanoparticle sizes increased with higher PVA proportions. The St/PVANPs showed superior performance as stabilizers in Pickering emulsions, forming denser continuous networks in the gel-like structure of the emulsions. Additionally, increasing the PVA content in the composition of St/PVANPs strengthened the structure of Pickering emulsions. The emulsion stabilized by St20/PVA80NPs showed exceptional stability for one month. These findings highlight the potential of St/PVANPs as innovative materials for various applications, including emulsion stabilization.
PubMed: 38925201
DOI: 10.1016/j.ijbiomac.2024.133406 -
International Journal of Biological... Jun 2024Chemical dust suppression is typically associated with high economic costs, unclear efficacy, and poor degradability. In this study, sodium alginate (SA) was extracted...
Chemical dust suppression is typically associated with high economic costs, unclear efficacy, and poor degradability. In this study, sodium alginate (SA) was extracted from kelp and cross-linked with polyvinyl alcohol (PVA) and polyacrylamide (PAM). Sulfonated castor oil (CAS) was subsequently added to generate a three-dimensional network hydrogel dust suppressant (PVA-SA-PAM/CAS). Using single-factor experiments, the optimal reaction temperature (60 °C) and dosages of PVA, PAM, and the cross-linking agent (2.5, 4.5, and 0.1 g, respectively) were determined. The viscosity and compressive strength of the prepared hydrogel were 86 mPa·s and 218 kPa, respectively, which meet the requirements for mine dust suppression. Various analyses revealed the hydrogel's reaction process and microstructure changes. Additionally, thermogravimetric experiments proved that the hydrogel had good thermal stability. The specific surface area and pore size of the hydrogel were 0.0278 m/g and 11.8 nm, respectively, improving its adsorption capacity. Additionally, PVA-SA-PAM/CAS exhibited a good water retention rate. The dust suppression efficiency of PVA-SA-PAM/CAS was >98 % under strong winds (12 m/s). Moreover, the degradation rate of PVA-SA-PAM/CAS was 37 % after eight cycles (56 d) under environmental conditions. Therefore, PVA-SA-PAM/CAS exhibits good wetting, dust suppression, and degradation properties, which can effectively alleviate mine dust pollution.
PubMed: 38925185
DOI: 10.1016/j.ijbiomac.2024.133408 -
Journal of Biomedical Materials... Jul 2024Sensorineural hearing loss (SNHL) is mainly caused by injury or loss of hair cells (HCs) and associated spiral ganglion neurons (SGNs) in the inner ear. At present,...
Sensorineural hearing loss (SNHL) is mainly caused by injury or loss of hair cells (HCs) and associated spiral ganglion neurons (SGNs) in the inner ear. At present, there is still no effective treatment for SNHL in clinic. Recently, advances in organoid bring a promising prospect for research and treatment of SNHL. Meanwhile, three-dimensional (3D) printing provides a tremendous opportunity to construct versatile organoids for tissue engineering and regenerative medicine. In this study, gelatin (Gel), sodium alginate (SA), and polyvinyl alcohol (PVA) were used to fabricate biomimetic scaffold through 3D printing. The organ of Corti derived from neonatal mice inner ear was seeded on the PVA/Gel/SA scaffold to construct organ of Corti organoid. Then, the organ of Corti organoid was used to study the potential protective effects of berberine sulfate on neomycin-juried auditory HCs and SGNs. The results showed that the PVA/Gel/SA biomimetic 3D scaffolds had good cytocompatibilities and mechanical properties. The constructed organoid could maintain organ of Corti activity well in vitro. In addition, the injury intervention results showed that berberine sulfate could significantly inhibit neomycin-induced HC and SGN damage. This study suggests that the fabricated organoid is highly biomimetic to the organ of Corti, which may provide an effective model for drug development, cell and gene therapy for SNHL.
Topics: Animals; Organ of Corti; Mice; Berberine; Tissue Scaffolds; Organoids; Printing, Three-Dimensional; Alginates; Gelatin; Hair Cells, Auditory; Tissue Engineering; Polyvinyl Alcohol; Hearing Loss, Sensorineural; Spiral Ganglion
PubMed: 38923766
DOI: 10.1002/jbm.b.35439 -
Advanced Science (Weinheim,... Jun 2024Ultralong room-temperature phosphorescent (URTP) materials have attracted wide attention in anti-counterfeiting, optoelectronic display, and bio-imaging due to their...
Ultralong room-temperature phosphorescent (URTP) materials have attracted wide attention in anti-counterfeiting, optoelectronic display, and bio-imaging due to their special optical properties. However, room-temperature blue phosphorescent materials are very scarce during applications because of the need to simultaneously populate and stabilize high-energy excited states. In this work, a stepwise stiffening chromophore strategy is proposed to suppress non-radiative jump by continuously reducing the internal spin of the chromophore, and successfully developing a series of blue phosphorescent materials. Phosphorescence lifetimes of more than 3 s are achieved, with the longest lifetime reaching 5.44 s and lasting more than 70 s in the naked eye. As far as is know, this is the best result that has been reported. By adjusting the chromophore conjugation, multicolor phosphorescences from cyan to green have been realized. In addition, these chromophores exhibit the same excellent optical properties in urea and polyvinyl alcohmance (PVA). Finally, these materials are successfully applied to luminescent displays.
PubMed: 38923328
DOI: 10.1002/advs.202402632