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The Open Microbiology Journal 2017and are relatively newcomers and emerging organisms in clinical and microbiological practice. Both species have worldwide been associated with urinary tract...
BACKGROUND
and are relatively newcomers and emerging organisms in clinical and microbiological practice. Both species have worldwide been associated with urinary tract infections. More rarely cases of bacteremia/septicemia and infective endocarditis have been reported. Treatment options are therefore important. Just recently, European recommendations on susceptibility testing and interpretive criteria have been released.
OBJECTIVE
In this investigation 120 and isolates were tested for susceptibility to six antimicrobial agents: Penicillin, cefotaxime, meropenem, vancomycin, linezolid, and rifampicin.
METHODS
Three susceptibility testing methods were used; disk diffusion according to The European Committee on Antimicrobial Susceptibility Testing (EUCAST) standardized disk diffusion methodology and MIC determination with Etest and broth microdilution (BMD). All testing was performed with EUCAST media for fastidious organisms.
RESULTS
Data obtained in this study were part of the background data for establishing EUCAST breakpoints. MIC values obtained by Etest and BMD were well correlated with disk diffusion results.
CONCLUSION
All isolates were found susceptible to all six antimicrobial agents: penicillin, cefotaxime, meropenem, vancomycin, linezolid, and rifampicin.
PubMed: 29151992
DOI: 10.2174/1874285801711010160 -
Journal of Community Hospital Internal... Mar 2017is a rare cause of infective endocarditis. Aerococcus is a gram positive cocci that is easily misidentified as Staphylococci or Streptococci. The true incidence rate of...
is a rare cause of infective endocarditis. Aerococcus is a gram positive cocci that is easily misidentified as Staphylococci or Streptococci. The true incidence rate of this pathogen is likely underestimated. Recent advances in laboratory diagnostic methods with matrix-associated laser desorption ionization time-of-flight mass spectrometry (MALDI-TOF-MS) have lead to increased recognition of this pathogen in the clinical microbiology lab, and awareness as a cause of infective endocarditis in the infectious disease community. Aerococcus usually affects males with underlying urinary tract conditions. Herein, we report a case of prosthetic aortic valve endocarditis caused by . Our patient was considered high risk for cardiac surgery and was treated successfully with intravenous antibiotics alone for six weeks. Infective endocarditis should be considered in all cases of bacteremia and appropriate diagnostic evaluations pursued. AV: Aortic valve; IE: Infective endocarditis.
PubMed: 28638578
DOI: 10.1080/20009666.2017.1314072 -
Infection & Chemotherapy Sep 2017Urosepsis due to Aerococcus urinae is rare in clinical settings with only a few of reported cases worldwide by 16S rRNA sequencing. Here we report a case of sepsis...
Urosepsis due to Aerococcus urinae is rare in clinical settings with only a few of reported cases worldwide by 16S rRNA sequencing. Here we report a case of sepsis caused by A. urinae in a 86 year-old male with complicated urinary tract infection which was confirmed through peptide mass fingerprinting of matrix-assisted laser desorption ionization time of flight mass spectrometry.
PubMed: 28608657
DOI: 10.3947/ic.2017.49.3.227 -
The New Microbiologica Jul 2017Aerococcus urinae is a microorganism responsible for urinary tract and blood stream infections which are rarely reported in clinical practice. However, it has been...
Aerococcus urinae is a microorganism responsible for urinary tract and blood stream infections which are rarely reported in clinical practice. However, it has been proposed that the infrequency of such reports may be partially due to difficulties related to pathogen identification. We present here a case of an elderly male patient with urinary tract infection where A. urinae was initially not identified by a private microbiology laboratory. Our report highlights the need to consider A. urinae as a causative agent of urinary tract infections because if not identified and properly treated it may lead to endocarditis or septicemia.
Topics: Aerococcus; Aged, 80 and over; Amoxicillin; Anti-Bacterial Agents; Bacteriuria; Diagnosis, Differential; Erythrocyte Count; Gram-Positive Bacterial Infections; Humans; Leukocyte Count; Male; Microbial Sensitivity Tests; RNA, Ribosomal, 16S; Urinary Tract Infections; Urine
PubMed: 28513811
DOI: No ID Found -
Urology Case Reports Jul 2017is a rare organism isolated from urine cultures. We present a case of an 80 year-old male with bladder cancer and multimorbidity who developed infection. may cause...
is a rare organism isolated from urine cultures. We present a case of an 80 year-old male with bladder cancer and multimorbidity who developed infection. may cause simple and complicated UTIs, bacteremia, and endocarditis in older adults with multimorbidity, chronic urinary retention, or indwelling catheters. treatment should employ penicillin, amoxicillin, and nitrofurantoin. Due to increasing antibiotic resistance, urine culture should include antibiotic susceptibility testing. Prompt and culture-specific treatment is critical to avoid clinical progression of the infection.
PubMed: 28435789
DOI: 10.1016/j.eucr.2017.03.022 -
JMM Case Reports Feb 2017An infection of the lower urinary tract associated with an extremely unpleasant odour due to in an otherwise healthy 5-year-old boy is described herein....
An infection of the lower urinary tract associated with an extremely unpleasant odour due to in an otherwise healthy 5-year-old boy is described herein. Interestingly, imaging examination revealed the presence of a bladder diverticulum. Routine microbiological examination based on Gram staining, colony morphology and catalase reactivity suggested that the responsible pathogen could belong either to staphylococci, α-haemolytic streptococci or enterococci, which are more common urine isolates. Of note is that the VITEK 2 automated system could not identify the micro-organism. Susceptibility testing showed full sensitivity to β-lactam antibiotics and resistance to trimethoprim/sulfamethoxazole. The isolate was subjected to 16S rRNA gene sequence analysis because of its unusual characteristics. It was identified as and the sequence was deposited in GenBank under the accession number KU207150. should be considered as a causative agent of urinary-tract infection associated with malodorous urine.
PubMed: 28348806
DOI: 10.1099/jmmcr.0.005083 -
Journal of Clinical and Diagnostic... Jan 2017Aerococci are Gram-positive cocci with colony morphology similar to viridans streptococci. Most often these isolates in clinical samples are misidentified and considered...
Aerococci are Gram-positive cocci with colony morphology similar to viridans streptococci. Most often these isolates in clinical samples are misidentified and considered insignificant. However, with the use newer techniques like Matrix-Assisted Laser Desorption Ionization Time-of-Flight Mass-Spectrometry (MALDI-TOF MS), aerococci have been recognized as significant human pathogens capable of causing a diverse spectrum of infections. Among the different species of aerococci, is the most common agent causing Urinary Tract Infection (UTI) followed by have been reported rarely in urinary tract infections. The antimicrobial resistance in aerococci in terms of its intrinsic resistance and evolving resistance to penicillin and vancomycin has raised the concern for better understanding of this pathogen. We recently encountered two cases of nosocomial UTI caused by which are being reported here.
PubMed: 28273968
DOI: 10.7860/JCDR/2017/23997.9229 -
IDCases 2017, a previously misidentified pathogen, has become increasingly recognized to cause severe and even fatal infections. Aerococcus-related perineal abscess infections have...
, a previously misidentified pathogen, has become increasingly recognized to cause severe and even fatal infections. Aerococcus-related perineal abscess infections have not previously been reported in the literature. Most reported cases of infections caused by Aerococcus are urinary tract infections, bacteremia, and even rare cases of endocarditis. We report an unusual case of a perineal abscess caused by .
PubMed: 28105405
DOI: 10.1016/j.idcr.2016.11.001 -
Journal of Global Infectious Diseases 2016
PubMed: 27942196
DOI: 10.4103/0974-777X.192964 -
BMJ Case Reports Jul 2016We present the case of an elderly male who was initially seen in our hospital for a urinary tract infection that was treated with oral ciprofloxacin. He was admitted...
We present the case of an elderly male who was initially seen in our hospital for a urinary tract infection that was treated with oral ciprofloxacin. He was admitted 2 weeks later with altered mental status and fever, and was found to have bacteraemia with Aerococcus urinae Owing to altered mental status a brain MRI was performed which showed evidence of embolic stroke. Following this, a transesophageal echocardiogram showed severe mitral regurgitation and a vegetation >1 cm involving the mitral valve with associated destruction of posterior valve leaflets. The patient was started on antibiotics intravenous penicillin G and intravenous gentamicin for a total duration of 6 weeks. He underwent mitral valve replacement on day 4 of hospitalisation. The postoperative course was complicated by ventilator-dependent respiratory failure, requiring tracheostomy and eventual transfer to a skilled nursing facility. Unfortunately, he died after 2 weeks of stay at the facility.
Topics: Aerococcus; Aged; Anti-Bacterial Agents; Brain; Echocardiography, Transesophageal; Endocarditis, Bacterial; Fatal Outcome; Gentamicins; Humans; Magnetic Resonance Imaging; Male; Mitral Valve; Mitral Valve Insufficiency; Penicillins; Stroke; Urinary Tract Infections
PubMed: 27440847
DOI: 10.1136/bcr-2016-215421