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Acta Dermato-venereologica Jul 2015
Topics: Adult; Anti-Bacterial Agents; China; Female; Humans; Immunocompromised Host; Lupus Erythematosus, Systemic; Mycobacterium Infections; Mycobacterium haemophilum; Skin Diseases, Bacterial
PubMed: 25710918
DOI: 10.2340/00015555-2076 -
JMM Case Reports Dec 2014is one of the non-tuberculous mycobacteria (NTM) that can cause cutaneous infection. As acid-fast staining cannot distinguish NTM from , and as skin culture for is not...
INTRODUCTION
is one of the non-tuberculous mycobacteria (NTM) that can cause cutaneous infection. As acid-fast staining cannot distinguish NTM from , and as skin culture for is not performed routinely, the diagnosis of infection in Thailand is rarely made.
CASE PRESENTATION
Between 2006 and 2009, five patients with infection were diagnosed in Ramathibodi Hospital, a tertiary care centre in Bangkok, Thailand. The patients were aged 3, 29, 47, 75 and 76 years, and four were immunocompromised. Three patients received immunosuppressive medication. Most patients presented with subacute cutaneous infection. A suboptimal response to conventional antibiotics raised suspicions of cutaneous infections, which can occur in immunocompromised patients. Diagnoses of these cases were made by skin culture for mycobacteria at an incubating temperature of around 30 °C with iron supplementation, DNA sequencing, or PCR/restriction enzyme analysis. Rifampicin, ofloxacin and clarithromycin were active against all isolates, whereas ethambutol and streptomycin were inactive.
CONCLUSION
Skin culture should be performed under special conditions or molecular technique should be used to identify in susceptible patients.
PubMed: 28663805
DOI: 10.1099/jmmcr.0.002618