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Journal of Clinical and Diagnostic... Jul 2015
PubMed: 26393181
DOI: 10.7860/JCDR/2015/14415.6257 -
Indian Journal of Dermatology 2015Onychomadesis or proximal separation of the nail pate usually results from severe, generalized dermatoses like bullous diseases, hand foot and mouth disease, varicella...
Onychomadesis or proximal separation of the nail pate usually results from severe, generalized dermatoses like bullous diseases, hand foot and mouth disease, varicella or severe cutaneous drug reactions. Although lichen planus (LP) produces varied nail manifestations (longitudinal onychorrhexis, onychoschizia, nail pigmentation, pterygium etc.), to the best of our knowledge, onychomadesis as a manifestation of nail LP is not recorded. This report presents two children with onychomadesis arising with generalized eruptive LP.
PubMed: 26288428
DOI: 10.4103/0019-5154.160512 -
Korean Journal of Family Medicine Mar 2015There have been a few reported cases of congenital great toenail dystrophy (GTND), described as a congenital malalignment of the great toenails. However, acquired GTDN...
BACKGROUND
There have been a few reported cases of congenital great toenail dystrophy (GTND), described as a congenital malalignment of the great toenails. However, acquired GTDN is rare, and has not been documented extensively. This study aimed to describe the clinical features of 21 patients with acquired GTND.
METHODS
Twenty-one patients with acquired GTND who visited Yeouido St. Mary's Hospital between June 2005 and August 2012 were retrospectively reviewed.
RESULTS
The mean patient age was 43.1 years (range, 17 to 88 years), and the cohort predominantly comprised women (18/21). In our experience, all acquired GTND patients presented with yellow or yellow-brownish chromonychia, onychotrophy, and onycholysis. Conservative treatment with tape methods and grinding, as well as nail extraction, was provided and yielded little improvement in any case.
CONCLUSION
This study provides initial data on the nail changes affecting the great toenail, such as yellowish chromonychia, onychomadesis, and onycholysis. These data may help physicians to distinguish various nail disorders, including onychomycosis, congenital malalignment of the great toenails, and yellow nail syndrome.
PubMed: 25802692
DOI: 10.4082/kjfm.2015.36.2.113 -
Neurology India 2015
Topics: Anticonvulsants; Carbamazepine; Child; Humans; Male; Yellow Nail Syndrome
PubMed: 25751489
DOI: 10.4103/0028-3886.152687 -
Zhongguo Dang Dai Er Ke Za Zhi =... Dec 2014
Topics: Child; Child, Preschool; Female; Hand, Foot and Mouth Disease; Humans; Infant; Male; Nail Diseases
PubMed: 25523580
DOI: No ID Found -
Annals of Dermatology Dec 2014
PubMed: 25473242
DOI: 10.5021/ad.2014.26.6.777 -
The Pan African Medical Journal 2014
Topics: Exanthema; Humans; Infant; Nail Diseases; Nails
PubMed: 25469196
DOI: 10.11604/pamj.2014.18.303.5022 -
Acta Veterinaria Scandinavica Oct 2014Treatment of symmetrical onychomadesis (symmetrical lupoid onychodystrophy) is a challenging task for dermatologists. The acute phase is characterized by sloughing of...
A treatment study of canine symmetrical onychomadesis (symmetrical lupoid onychodystrophy) comparing fish oil and cyclosporine supplementation in addition to a diet rich in omega-3 fatty acids.
BACKGROUND
Treatment of symmetrical onychomadesis (symmetrical lupoid onychodystrophy) is a challenging task for dermatologists. The acute phase is characterized by sloughing of claw plates and loose claws have to be removed and secondary infections treated. The goal of long-term treatment is to allow claws to re-grow with normal quality and to achieve life-long lack of recurrence. The aim of this randomized treatment trial was to see if adding fish oil or cyclosporine to a diet rich in omega-3 could improve the treatment outcome of symmetrical onychomadesis in Gordon and English setters. All dogs were fed Eukanuba Veterinary Diets Dermatosis® exclusively during the six month treatment trial. The treatment outcome was measured as the change in number of healthy claws during treatment, as well as the long-term effect on hunting ability and recurrence of onychomadesis. The hypothesis was that cyclosporine provides a stronger and different immune modulating property than fish oil and therefore would give a better treatment outcome in dogs with symmetrical onychomadesis eating a diet rich in omega-3 fatty acids.
RESULTS
Six Gordon setters and one English setter were treated with 5 mg/kg cyclosporine once daily for six months and seven Gordon setters were treated with 10 ml Dr Baddaky fish oil® once daily for six months. All dogs were evaluated every month and the numbers of healthy claws were recorded.
CONCLUSION
Cyclosporine and fish oil appeared to be equally effective in treating symmetrical onychomadesis when the dog is fed a diet high in omega-3.
Topics: Animals; Cyclosporine; Diet; Dog Diseases; Dogs; Fatty Acids, Omega-3; Fish Oils; Nail Diseases; Treatment Outcome
PubMed: 25280860
DOI: 10.1186/s13028-014-0066-y -
Indian Pediatrics Aug 2014
Topics: Child, Preschool; Female; Fingers; Hand, Foot and Mouth Disease; Humans; Nail Diseases; Nails
PubMed: 25129012
DOI: 10.1007/s13312-014-0481-1 -
Anales de Pediatria (Barcelona, Spain :... Apr 2015Due to the significant increase in the number of cases of hand, foot and mouth disease (HFMD) among pre-school children population during late 2011 and early 2012. A...
INTRODUCTION
Due to the significant increase in the number of cases of hand, foot and mouth disease (HFMD) among pre-school children population during late 2011 and early 2012. A study has been proposed with the aim of describing the HFMD outbreak and analyzing the risk factors associated with suffering onychomadesis.
PATIENTS AND METHODS
A descriptive and analytical case-control study was designed. The study population was 376 children between 6 and 36 months old, living in the Basic Health Catchment area of Peligros (Granada). The study inclued an epidemiological survey of 28 cases and paired controls in order to collect data on the time, person and place, and implementing preventive actions and family health education. Finally a microbiological viral study of stool samples was made.
RESULTS
There were 64% of girls with average age 20.8 months. The clinical signs fornd were, fever (75%), vesicular palmar eruption (71%), plantar eruption (68%), erosive stomatitis (64%), and nail loss (46%). The risk of getting sick was 14 times greater for those children attending a childcare centre and had contact with sick cases (OR 13.8; 95% CI; 3.79-50.18). The average time since onset of symptoms and onychomadesis was 52 days, and its appearance was linked to the presence of ulcers in mouth (P=.006). Five samples were positive to enteroviruses Coxsackie A16.
CONCLUSION
There was an outbreak of HFMD detected by pediatricians and families. The cases presented with marked clinical symptoms, and the nail loss (onychomadesis) generated a social alarm. The cause of the outbreak was an enterovirus Coxsackie A16 transmitted among sick cases and through childcare centres.
Topics: Case-Control Studies; Child, Preschool; Disease Outbreaks; Enterovirus; Female; Hand, Foot and Mouth Disease; Humans; Infant; Male; Nail Diseases; Spain
PubMed: 25027620
DOI: 10.1016/j.anpedi.2014.05.015