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Journal of Indian Society of... 2019Periodontal plastic surgery often involves palatal donor site, thereby creating an open wound that is prone to postoperative complications such as bleeding, pain, and...
Periodontal plastic surgery often involves palatal donor site, thereby creating an open wound that is prone to postoperative complications such as bleeding, pain, and slow healing process. To prevent the same, platelet-rich fibrin (PRF) and gelatin sponge (GS) were utilized equally at the donor site in six patients. Patients were monitored at the 1, 2, 3, and 4 weeks after surgery for postoperative discomfort (D), consumption of analgesics during first postoperative week, alteration of sensitivity (AS), change in feeding habits (CFH), complete wound epithelialization (CWE), and healing index (Landry 1998). Two patients in the GS group showed significantly early CWE, higher healing index score, and less D, AS, and CFH postoperatively in comparison to the PRF group. It was suggested that GS can also be considered as an effective, economical, and biocompatible dressing material of choice to enhance wound healing and to minimize postoperative complications associated with the donor site.
PubMed: 31849408
DOI: 10.4103/jisp.jisp_165_19 -
Clinics and Practice Aug 2019Pyogenic granuloma is a non-neoplastic, exuberant, reactive lesion seen in response to local irritation or trauma caused by dental calculus, bacterial plaque, caries and...
Pyogenic granuloma is a non-neoplastic, exuberant, reactive lesion seen in response to local irritation or trauma caused by dental calculus, bacterial plaque, caries and restorations, with a strong predilection for the gingiva. It is among the frequently encountered oral lesions, occurring at a challenging oral site, the gingiva. Herein, we report a 71-year-old medically compromised Caucasian female who presented with a relatively large lobulated pyogenic granuloma on the buccal gingiva of the maxillary molar-premolar region. Total surgical excision was performed with an 840nm diode laser followed by the placement of hyaluronate gel and relevant periodontal dressing. Two weeks after surgical excision, complete healing was observed, but patient denied replacement of dental restoration. After 4 months of follow-up, an overall reduction of associated teeth mobility was also observed, with a minor recurrence in gingival inflammation. The objective of this report is to briefly review clinical, radiographic and histological findings of pyogenic granuloma along with a detailed discussion on its management through a diode laser.
PubMed: 31579498
DOI: 10.4081/cp.2019.1179 -
Brazilian Oral Research 2019This study evaluated the effect of antimicrobial photodynamic therapy (aPDT) on the endodontic treatment of apical periodontitis (AP). AP was induced in 48 premolars of...
This study evaluated the effect of antimicrobial photodynamic therapy (aPDT) on the endodontic treatment of apical periodontitis (AP). AP was induced in 48 premolars of 6 dogs. After biomechanical preparation, the teeth were divided into 4 groups: Calcium-Hydroxide (CH)/120d and CH/180d: root canals filled with CH-based dressing for 15 days before obturation; aPDT/120d and aPDT/180d: conditioning with phenothiazine photosensitizer (10 mg/mL) for 1 minute and irradiation with diode laser in the same session as obturation. Root filling was performed with AH Plus sealer. After the experimental periods, animals were euthanized and teeth were submitted for histology. HE staining was performed for descriptive analysis of the periapical region, measurement of apical periodontitis and for inflammatory cells, and blood vessels count. Immunohistochemistry was performed for osteopontin (OPN) and alkaline phosphatase (ALP). Data were analyzed statistically by two-way ANOVA and chi-square test (α = 5%). Teeth in Group CH/120d presented only a slightly enlarged periodontal ligament (PL) with advanced repair. Group aPDT/120d presented the PL moderately enlarged, with moderate inflammatory infiltrate and few collagen fibers. The same pattern was observed at 180 days. AP lesions in CH-treated groups were smaller than those in aPDT-treated groups (p < 0.001) with more blood vessels (p < 0.0001), regardless of the evaluation period, without significant differences in the number of inflammatory cells (p > 0.05). CH-treated groups showed significantly more intense immunostaining for ALP and OPN (p < 0.001) in both periods. Although aPDT stimulated angiogenesis and expression of bone formation markers, the two-session endodontic treatment with CH-based dressing promoted better apical periodontitis repair.
Topics: Animals; Blood Vessels; Bone Cements; Bone Regeneration; Calcium Hydroxide; Immunohistochemistry; Neovascularization, Physiologic; Periapical Periodontitis; Photochemotherapy; Reproducibility of Results; Root Canal Therapy; Time Factors; Treatment Outcome
PubMed: 31576904
DOI: 10.1590/1807-3107bor-2019.vol33.0092 -
Revascularization of a Nonvital, Immature Permanent Tooth Using Amniotic Membrane: A Novel Approach.International Journal of Clinical... 2019To evaluate the clinical and radiological results of a revascularization treatment done in a nonvital, immature permanent tooth using the amniotic membrane.
AIM
To evaluate the clinical and radiological results of a revascularization treatment done in a nonvital, immature permanent tooth using the amniotic membrane.
CASE DESCRIPTION
A 12-year-old boy reported with a complaint of pain in the lower left back tooth since 1 month due to dental caries. On clinical examination, the mandibular left second premolar was tender on percussion and discolored due to dental caries. Radiographic examination of the same tooth revealed open apex, thin root dentinal walls, and periodontal ligament widening. An access opening was prepared, necrotic pulp extirpated completely followed by thorough irrigation. After drying the canal, closed dressing with the 3-mix antibacterial paste was given for 15 days. After 15 days, the paste was removed and the amniotic membrane was placed inside the canal extending 1 mm beyond the apex and mineral tri-oxide aggregate was placed over this followed by sealing of the cavity. The patient was followed up at 1, 3, and 6 months for clinical and radiographic evaluation.
CONCLUSION
After 6 months, clinically the tooth found asymptomatic. Radiographic examination showed continued root elongation, closure in the periapical opening, thick root dentinal walls with narrowing of the canal space, and normal periradicular architecture.
CLINICAL SIGNIFICANCE
Amniotic membrane can be used as a scaffold for revascularization in nonvital immature teeth.
HOW TO CITE THIS ARTICLE
NB Nagaveni, P Poornima, Revascularization of a Nonvital, Immature Permanent Tooth Using Amniotic Membrane: A Novel Approach. Int J Clin Pediatr Dent 2019;12(2):150-152.
PubMed: 31571789
DOI: 10.5005/jp-journals-10005-1596 -
Journal of Indian Society of... 2019The platelet-rich fibrin (PRF) has proven an immense role in angiogenesis and epithelization in a wound healing process. The present study aims to ascertain PRF's...
BACKGROUND
The platelet-rich fibrin (PRF) has proven an immense role in angiogenesis and epithelization in a wound healing process. The present study aims to ascertain PRF's beneficial role in wound healing after depigmentation surgery.
MATERIALS AND METHODS
A total of 12 systemically healthy controls included were divided into two groups after scalpel depigmentation procedure. PRF was prepared according to Choukroun's standard protocol. Using split-mouth design after depigmentation, one group received PRF membrane, and in second group non-eugenol periodontal dressing was placed. The participants were evaluated for visual analog scale (VAS), healing index (HI) on 3 and 5 day. Epithelization test using toluidine blue and histological examination employing punch biopsy was done on the 5 day.
RESULTS
On statistical scale, VAS, HI, epithelization test, and histological findings were statistically significant in the two study groups. PRF group proved better epithelization test and inflammatory cell infiltration was less in PRF group which confirmed superior wound healing in the group.
CONCLUSION
PRF membrane postdepigmentation provided satisfactory patient comfort and enhanced the wound healing cascade.
PubMed: 31367132
DOI: 10.4103/jisp.jisp_688_18 -
International Journal of Clinical... 2018Conservation of primary dentition is essential for maintenance of arch length, esthetic, mastication, speech and prevention of abnormal habits. The commonly supported...
INTRODUCTION
Conservation of primary dentition is essential for maintenance of arch length, esthetic, mastication, speech and prevention of abnormal habits. The commonly supported treatment for retaining carious primary molars with affected pulp is pulpotomy.
AIM
The study aims to evaluate clinically and radiographically the rates of success and efficacy of Biodentine™ as pulpotomy medicament exclusively on primary molars with physiological root resorption.
MATERIALS AND METHODS
A total number of 35 primary molars in stage three of formation were selected to undergo pulpotomy treatment. All teeth were restored with pediatric stainless-steel crowns.The clinical findings were evaluated at 1, 3, 6 and 12-month intervals and the radiographic follow-ups evaluations were done at 6 and 12 months. The resulting data were tabulated and statistically analyzed using IBM SPSS© for Windows version 20.0 (SPSS, Chicago, IL, USA). Mc Nemar test was conducted to evaluate the differences in results between months 6 and 12.
RESULTS
Periodontal ligament space (PLS) widening and alveolar bone lesion were not seen in any of the 35 cases, 9 teeth (25.7%) manifested pulp canal obliteration (PCO), and none of the cases showed signs of pathologic root resorption. The clinical and radiographic success rates in pulpotomy using Biodentine™ at 6 and 12 months were 100%.
CONCLUSION
Pulpotomies performed with Biodentine™ were entirely successful. This dressing material appears to be a serious pulpotomy agent in primary molars with root resorption. Nasseh HN, Noueiri BE, Pilipili C, Ayoub F. Evaluation of Biodentine Pulpotomies in Deciduous Molars with Physiological Root Resorption (Stage 3). Int J Clin Pediatr Dent., 2018;11(5):393-398.
PubMed: 30787552
DOI: 10.5005/jp-journals-10005-1546 -
Contemporary Clinical Dentistry Sep 2018Zinc oxide-eugenol dressing is widely used in the dentistry field. Eugenol in wound dressing acts as an antibacterial and analgesic agent but known to cause...
INTRODUCTION
Zinc oxide-eugenol dressing is widely used in the dentistry field. Eugenol in wound dressing acts as an antibacterial and analgesic agent but known to cause hypersensitivity reaction and allergies. rhizome extract could perform as a substitute of eugenol as its active compounds have an anti-inflammation, antioxidant, anticancer, and antibacterial properties. It has also been shown to have proangiogenic and promote wound healing. This study aimed to discover the number of neovascular in the wound healing process after the application of zinc oxide and rhizome extract wound dressing.
MATERIALS AND METHODS
Full-thickness excision wound of 6 mm × 6 mm was made in the dorsal of 32 Wistar strains Rattus norvegicus, before being equally divided into eight groups ( = 4): four control groups (C3, C5, C7, and C14) without any dressing and 4 treatment groups (T3, T5, T7, and T14) were dressed with zinc oxide and extract wound dressing. The rats consecutively sacrificed on day 3 (C3, T3), day 5 (C5, T5), day 7 (C7, T7), and day 14 (C14, T14) to observe the neovascular pattern and number using H and E staining. Obtained data were analyzed using ANOVA.
RESULTS
The neovascular growth in both control and treatment groups have the same pattern, while the number of neovascular in treatment groups significantly higher than the control groups ( < 0.05).
CONCLUSIONS
Wound dressing combination of zinc oxide and extract can increase the number of neovascular in the wound healing process, while the optimum duration of application is 14 days.
PubMed: 30294168
DOI: 10.4103/ccd.ccd_435_18 -
European Journal of Dentistry 2018Studies about the dispersion of hydroxyl ions through dentin of endodontically retreated teeth are scarce. The present study aims at examining the diffusion of calcium...
OBJECTIVE
Studies about the dispersion of hydroxyl ions through dentin of endodontically retreated teeth are scarce. The present study aims at examining the diffusion of calcium hydroxide by recording the pH changes of retreated root canal using two types of calcium hydroxide preparations.
MATERIALS AND METHODS
A total of 45 recently extracted single-rooted mandibular first premolars were collected and cleaned from calculus and remains of periodontal tissue. The teeth so collected were stored in thymol 10% solution till use. During collection, teeth with cracks, open apices, and restorations were excluded. Root canal preparations were performed using Protaper rotary system files, till #F3 file. All canals were obturated using cold lateral condensation and zinc oxide-based sealer. After 7 days, all gutta-percha were removed and the canals were irrigated with normal saline. The teeth were then randomly distributed into three groups. Canals in Group I were kept empty without any dressing to serve as a negative control group, Canals in Group II were filled with a freshly prepared mixture of calcium hydroxide powder with normal saline solution, and Group III was filled with Metapex. Periodically, the calcium hydroxide material was removed and the pH was measured using pH meter at 7, 10, 14, and 30 days.
RESULTS
The pH values of Group II and III ranged between 9.2 and 11.2. This was found to be highly significant against the negative control group. After 7 and 10 days, freshly mixed Ca(OH) showed the higher pH than the creamy Metapex, and statistically the difference was highly significant after 10 days (<0.001). After 14 days, Metapex group pH was higher than freshly mixed Ca(OH), but it was not statistically significant as they reached nearly the same pH after 30 days (>0.05).
CONCLUSION
All Ca(OH) preparations had high pH around the roots after 7 and 10 days. Metapex continued to have higher pH after 14 days.
PubMed: 30147404
DOI: 10.4103/ejd.ejd_77_18 -
BMC Musculoskeletal Disorders Aug 2018Lumbar intervertebral disc herniation is a common cause of lower back and leg pain, with surgical intervention (e.g. discectomy to remove the herniated disc) recommended... (Meta-Analysis)
Meta-Analysis Review
BACKGROUND
Lumbar intervertebral disc herniation is a common cause of lower back and leg pain, with surgical intervention (e.g. discectomy to remove the herniated disc) recommended after an appropriate period of conservative management, however the existing or increased breach of the annulus fibrosus persists with the potential of reherniation. Several prosthesis and techniques to reduce re-herniation have been proposed including implantation of an annular closure device (ACD) - Barricaid™ and an annular tissue repair system (AR) - Anulex-Xclose™. The aim of this meta-analysis is to assist surgeons determine a potential approach to reduce incidences of recurrent lumbar disc herniation and assess the current devices regarding their outcomes and complications.
METHODS
Four electronic full-text databases were systematically searched through September 2017. Data including outcomes of annular closure device/annular repair were extracted. All results were pooled utilising meta-analysis with weighted mean difference and odds ratio as summary statistics.
RESULTS
Four studies met inclusion criteria. Three studies reported the use of Barricaid (ACD) while one study reported the use of Anulex (AR). A total of 24 symptomatic reherniation were reported among 811 discectomies with ACD/AR as compared to 51 out of 645 in the control group (OR: 0.34; 95% CI: 0.20,0.56; I = 0%; P < 0.0001). Durotomies were lower among the ACD/AR patients with only 3 reported cases compared to 7 in the control group (OR: 0.54; 95% CI: 0.13, 2.23; I = 11%; P = 0.39). Similar outcomes for post-operative Oswestry Disability Index and visual analogue scale were obtained when both groups were compared.
CONCLUSION
Early results showed the use of Barricaid and Anulex devices are beneficial for short term outcomes demonstrating reduction in symptomatic disc reherniation with low post-operative complication rates. Long-term studies are required to further investigate the efficacy of such devices.
Topics: Adolescent; Adult; Aged; Biomechanical Phenomena; Diskectomy; Female; Humans; Intervertebral Disc; Intervertebral Disc Displacement; Lumbar Vertebrae; Male; Middle Aged; Periodontal Dressings; Postoperative Complications; Prosthesis Design; Recovery of Function; Recurrence; Resins, Synthetic; Risk Factors; Time Factors; Total Disc Replacement; Treatment Outcome; Young Adult
PubMed: 30115053
DOI: 10.1186/s12891-018-2213-5 -
Iranian Endodontic Journal 2018The aim of this study was to compare the antibacterial effects of two gels containing zinc oxide and zinc oxide/silver nanoparticles and a mixture of calcium hydroxide...
INTRODUCTION
The aim of this study was to compare the antibacterial effects of two gels containing zinc oxide and zinc oxide/silver nanoparticles and a mixture of calcium hydroxide and 0.12% chlorhexidine as intracanal medicaments in root canals contaminated with () at different time intervals.
METHODS AND MATERIALS
After preparation and culturing of in 132 single root teeth, the initial count of bacteria was performed. Then, different materials as intracanal medicaments were used in periods of 3, 7 and 14 days (group 1: calcium hydroxide with 0.12% CHX paste; group 2 zinc oxide nanoparticles gel; group 3: zinc oxide/silver nanoparticles gel; group 4: normal saline as the control group). After the specified time, intracanal medicament was removed and the final count of bacteria was performed. Antibacterial effect of materials was counted by measuring the percentage reduction in the colony counts (RCC). Data were analyzed using the descriptive statistics (Mean±SD) and multi-factorial analysis of variance (by taking into account the effect of the time factor on the dependent variable).
RESULTS
There were no statistically significant differences among mean RCC of different time intervals in each group (=0.09). However, the differences in mean RCC of different dressing materials were significant (<0.001). The effect of interaction between time and materials was significant (=0.015). Comparison of the antibacterial effects of experimental agents at different time intervals showed that the mean RCC in group 1 was higher than other groups (<0.001). The difference in antibacterial effect between groups 2 and 3 was not significant (>0.05). The minimum antibacterial effect was observed in group 4 (<0.0001).
CONCLUSIONS
The mixture of calcium hydroxide/chlorhexidine as an intracanal medicament was more effective than zinc oxide and zinc oxide/silver nanoparticles gels.
PubMed: 30083198
DOI: 10.22037/iej.v13i3.19866