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Pediatric Dermatology 2024Pediatric dermatitis and nonaccidental trauma (NAT) may have overlapping cutaneous presentations, posing a risk of misdiagnosis and subsequent emotional distress and...
BACKGROUND/OBJECTIVES
Pediatric dermatitis and nonaccidental trauma (NAT) may have overlapping cutaneous presentations, posing a risk of misdiagnosis and subsequent emotional distress and further harm. Through a systematic literature review, we reviewed pediatric (<18 years old) patients investigated for both dermatitis and NAT.
METHODS
EMBASE and MEDLINE databases were searched. English publications with original data involving pediatric patients investigated for both dermatitis and NAT were included. Nonhuman studies and incomplete articles/conference abstracts were excluded. Data extracted included the first author, year of publication, study design, participant count, sex of the population, age of the population, cutaneous presentation, timing of presentation, Child Protective Services involvement, and case relation to dermatitis and NAT.
RESULTS
This review included 21 case reports or series encompassing 29 patients. Among 26 patients initially investigated as NAT (26.9% involving Child Protective Services), final diagnoses included irritant contact dermatitis (53.8%), phytophotodermatitis (30.8%), allergic contact dermatitis (7.7%), perianal infectious dermatitis (3.8%), and atopic dermatitis (3.8%). Three patients initially diagnosed with nontraumatic dermatitis were later found to be victims of physical (2/3; 66.7%) or sexual abuse (1/3; 33.3%).
CONCLUSIONS
Effective history-taking and physical examinations should encompass a history of laxative use, contact with furocoumarin-containing plants/fruit, parallel family/peer cutaneous presentations, caregiver involvement, financial burden, patient discomfort, birthmark assessment, and lesions aligning with diaper borders or toilet seats. Limitations of this review include potential underreporting and the inclusion of low-quality study designs and evidence.
Topics: Child; Humans; Adolescent; Child Abuse; Laxatives; Dermatitis, Phototoxic; Dermatitis, Atopic; Diagnostic Errors
PubMed: 38400817
DOI: 10.1111/pde.15556 -
Environmental Pollution (Barking, Essex... Jan 2024As aluminum nanoparticles (Al-NPs) are widely used in our daily life and various industries, Al-NPs has been becoming an emerging pollution in the environment. The... (Review)
Review
As aluminum nanoparticles (Al-NPs) are widely used in our daily life and various industries, Al-NPs has been becoming an emerging pollution in the environment. The impact of this NP has been attracting more and more attention from the scientific communities. In this review, we systematically summarized the interactions, uptake, and transport of Al-NPs in the plant system. Al-NPs can enter plants through different pathways and accumulate in various tissues, leading to alter plant growth and development. Al-NPs also affected root, shoot, and leaf characteristics as well as changing nutrient uptake and distribution and inducing oxidative stress via excess reactive radical generation, thereby impairing plant defense systems. Additionally, Al-NPs altered gene expression, which involved in various signaling pathways and metabolic processes in plants, that further altered plants susceptible or tolerant to stressors. The review also emphasized the effects of Al-NP size, surface charge, concentration, and exposure duration on plant growth and development. In the future, more research should be focused on mechanisms underlying Al-NPs phytotoxicity and potential risk to humans and off-target species.
Topics: Humans; Aluminum; Plant Development; Artesunate; Biological Transport; Nanoparticles
PubMed: 37931678
DOI: 10.1016/j.envpol.2023.122875