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Heliyon Feb 2024The Old World Vultures (OWV), constituting 16 species primarily in Africa, Europe and Asia, are currently being driven to extinction mostly by anthropogenic activities,...
The Old World Vultures (OWV), constituting 16 species primarily in Africa, Europe and Asia, are currently being driven to extinction mostly by anthropogenic activities, especially poisoning. The vulture losses from poisoning caused by human-related activities are at a single mortality event-level and occur in complex social-ecological systems. There has been a growing body of knowledge on wildlife poisoning over the years. However, no review has been done to consolidate vulture poisoning studies in sub-Saharan Africa (SSA), with a social lens of conservation planning. Here we present a review of the vulture poisoning research by re-contextualizing the problem of vulture poisoning across SSA. We employed stepwise Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) method to search for literature on vulture poisoning. The search yielded 211 studies which were trimmed to 55 after applying sets of eligibility criteria. Literature shows that efforts aimed at successful vulture conservation planning will require an understanding of the relational aspects of stakeholder social capital (assets) that are critical to the implementation of species recovery strategies. Strengthening relational social capital through multi-scale stakeholder evidence-based awareness creation and participation is necessary for addressing the African Vulture Crisis (AVC). Applying stakeholder social capital approaches to different vulture conservation scenarios at local, regional and international scales can enhance successful implementation of conservation strategies for the persistence of vultures in complex socio-ecological systems in African landscapes. Existing literature also showed the importance of stakeholder social capital as a countermeasure against vulture losses.
PubMed: 38333820
DOI: 10.1016/j.heliyon.2024.e25126 -
Toxicon : Official Journal of the... Dec 2023Some plant species of the genus Cestrum L. (Solanaceae family) are known to cause poisoning in farming animals in Brazil, negatively affecting the livestock sector. In... (Review)
Review
Some plant species of the genus Cestrum L. (Solanaceae family) are known to cause poisoning in farming animals in Brazil, negatively affecting the livestock sector. In this context, this study aimed to carry out a systematic review of the Cestrum species that cause poisoning in ruminants in Brazil and to list the main phytochemicals involved in these toxic activities that have already been identified. Scientific documents were retrieved in Google Scholar, PubMed®, ScienceDirect®, and SciELO databases. After applying the inclusion criteria, a total of 38 articles published between 1920 and 2023 were included in the present study. Cestrum axillare Vell. [Syn. Cestrum laevigatum Schltdl.], Cestrum corymbosum Schltdl., Cestrum intermedium Sendtn., and Cestrum parqui L'Hér. were found to have reported cases of poisoning in the Northeast, Southeast, and South of Brazil. Natural poisonings in ruminants caused by these species have been recorded in ten Brazilian states, mostly in Rio de Janeiro, Santa Catarina, Rio Grande do Sul, and Pernambuco. In general, Cestrum species cause liver damage and a clinical-pathological state characterized by acute liver failure of the poisoned animals. Cattle are more susceptible to poisoning by these plants, but there are reports of poisoning by C. axillare in goats and buffaloes as well. Several chemical constituents were identified in C. axillare and C. parqui, including some saponins and terpenoids that may be associated with the cases of poisoning. However, only one chemical compound has been identified in C. intermedium, and no phytochemical investigation has been carried out regarding toxic compounds in C. corymbosum. It is expected that future studies fill the gap in determining the toxic principles present in these species.
Topics: Cattle; Animals; Solanaceae; Cestrum; Brazil; Liver Diseases; Goats
PubMed: 37981013
DOI: 10.1016/j.toxicon.2023.107348 -
Environmental Science and Pollution... Aug 2023The liver is a central target organ of heavy metals toxicity, and secondary metabolites of several plant species are suggested to attenuate lead (Pb)-induced... (Review)
Review
The liver is a central target organ of heavy metals toxicity, and secondary metabolites of several plant species are suggested to attenuate lead (Pb)-induced hepatotoxicity through antioxidant and anti-inflammatory mechanisms. We used a systematic review framework to map the impact of plant extracts and bioactive secondary metabolites on immunological markers and liver redox metabolism in preclinical models of Pb exposure. This is a systematic review performed according to PRISMA guidelines. The structured research of publications was done through PubMed, Scopus, Web of Science, and Embase databases, selecting and analyzing 41 original studies included via the eligibility criteria. Evidence indicates that Pb-exposure increases reactive oxygen/nitrogen species (ROS/RNS) production by δ-aminolevulinic acid auto-oxidation, xanthine dehydrogenase, and xanthine oxidase upregulation. Pb exposure also inhibits antioxidant enzymes, potentiating ROS/NOS levels and reactive cell damage. Plant extracts rich in flavonoids, tannins, alkaloids, anthocyanins, and vitamins exerted hepatoprotective effects by chelating and decreasing Pb bioaccumulation. In addition, plant extracts reinforce exogenous and endogenous antioxidant defenses, attenuating liver oxidative stress and cell death. The lack of blinded evaluators and randomized experimental groups were the main sources of bias identified, which need to be controlled in toxicological studies aimed at identifying natural products applied to the prevention or treatment of Pb poisoning.
Topics: Antioxidants; Reactive Oxygen Species; Lead; Anthocyanins; Oxidative Stress; Oxidation-Reduction; Plants; Plant Extracts
PubMed: 37495800
DOI: 10.1007/s11356-023-28620-8