-
International Journal of Systematic and... Sep 2023Average nucleotide identity analysis, based on whole genome sequences of 115 strains previously identified as , an emerging uropathogen, discriminates at least six...
Average nucleotide identity analysis, based on whole genome sequences of 115 strains previously identified as , an emerging uropathogen, discriminates at least six unique genomic taxa. The whole genome analysis affords clearer species boundaries over 16S rRNA gene sequencing and traditional phenotypic approaches for the identification and phylogenetic organization of species. The newly described species can be differentiated by matrix-assisted laser desorption ionization time-of-flight analysis of protein signatures. We propose the emendation of the description of (type strain ATCC 51268 = CCUG 34223=NCFB 2893) and the names of sp. nov. (ATCC TSD-302 = DSM 115700 = CCUG 76531=NR-58630) sp. nov. (ATCC TSD-301 = DSM 115699 = CCUG 76532=NR-58629) and sp. nov. (ATCC TSD-300 = DSM 115698 = CCUG 76533=NR-58628) for three of the newly identified genomic taxa.
Topics: Aerococcus; Phylogeny; RNA, Ribosomal, 16S; Sequence Analysis, DNA; DNA, Bacterial; Bacterial Typing Techniques; Base Composition; Fatty Acids
PubMed: 37755156
DOI: 10.1099/ijsem.0.006066 -
BMJ Case Reports Sep 2023An elderly male with an extensive medical history was admitted for sepsis of unspecified origin; the source was later found to be an urinary tract infection. Urinalysis...
An elderly male with an extensive medical history was admitted for sepsis of unspecified origin; the source was later found to be an urinary tract infection. Urinalysis and conventional urine culture were used in diagnosing this infection, and it was successfully treated with a 7-day course of intravenous ceftriaxone. The patient had no recurrence of urinary symptoms or development of complications at his follow-up. While has traditionally been described as an uncommon and relatively avirulent source of urinary tract infections, increasing reports of positive isolation suggest its incidence may be higher than previously believed. Cases have been more frequently reported among elderly males with multimorbidity and repeat hospitalisation. A lower threshold of suspicion for urinary tract infections in this population may better guide empiric therapy and help avoid potentially life-threatening complications.
Topics: Aged; Humans; Male; Urinary Tract Infections; Aerococcus; Ceftriaxone; Administration, Intravenous
PubMed: 37730420
DOI: 10.1136/bcr-2023-257496 -
Clinical Microbiology and Infection :... Aug 2023
Topics: Humans; Fosfomycin; Aerococcus; Anti-Bacterial Agents; Urinary Tract Infections; Gram-Positive Bacterial Infections
PubMed: 37179008
DOI: 10.1016/j.cmi.2023.04.029