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The Saudi Dental Journal Jun 2024To explore the feasibility and effectiveness of using sandblasting with aluminum oxide particles to improve the shear bond strength of labial veneer restorations in...
OBJECTIVES
To explore the feasibility and effectiveness of using sandblasting with aluminum oxide particles to improve the shear bond strength of labial veneer restorations in dentistry.
MATERIALS AND METHODS
A sample size of 50 extracted teeth was divided into five groups, with each group containing ten teeth (n = 10) subject to different treatment protocols. Group 1the control group, underwent conventional surface treatment for labial veneer restorations, including the application of phosphoric acid etchant and bonding protocols. Groups 2 and 3 underwent micro-abrasion using aluminum oxide particles alone for durations of 30 and 45 s, respectively. Groups 4 and 5 experienced a combined approach of micro-abrasion for 30 and 45 s, respectively, followed by conventional surface treatment. The shear bond strength test was performed on each specimen. The resulting modes of failure and surface characteristics were then examined under a digital microscope.The data was analyzed statistically using a one-way analysis of variance (ANOVA) and a post hoc test.
RESULTS
Significant differences were observed in shear bond strength among the five groups (p < 0.05). The group that underwent conventional + 45-second micro-abrasion treatment exhibited the highest mean shear bond strength (25.69 MPa), while the conventional (controlled) group had the lowest (9.01 MPa).
CONCLUSION
Fusing sandblasting and aluminum oxide particles could improve the bond strength of labial veneer restorations. Yet, more research is needed to refine this technique for practical application. This includes a broad array of cement types, particle sizes, and clinical situations to ensure the long-term success of veneer restorations.
PubMed: 38883910
DOI: 10.1016/j.sdentj.2024.04.003 -
International Journal of Nanomedicine 2024Metal-organic frameworks (MOFs) are porous materials resulting from the coordination of metal clusters or ions with organic ligands, merging macromolecular and... (Review)
Review
Metal-organic frameworks (MOFs) are porous materials resulting from the coordination of metal clusters or ions with organic ligands, merging macromolecular and coordination chemistry features. Among these, zeolitic imidazolate framework-8 (ZIF-8) stands out as a widely utilized MOF known for its robust stability in aqueous environments owing to the robust interaction between its constituent zinc ions (Zn) and 2-methylimidazole (2-MIM). ZIF-8 readily decomposes under acidic conditions, serving as a promising candidate for pH-responsive drug delivery systems. Moreover, biomimetic materials typically possess good biocompatibility, reducing immune reactions. By mimicking natural structures or surface features within the body, they enhance the targeting of nanoparticles, prolong their circulation time, and increase their bioavailability in vivo. This review explores the latest advancements in biomimetic ZIF-8 nanoparticles for drug delivery, elucidating the primary obstacles and future prospects in utilizing ZIF-8 for drug delivery applications.
Topics: Metal-Organic Frameworks; Humans; Biomimetic Materials; Zeolites; Nanoparticles; Drug Delivery Systems; Imidazoles; Animals; Zinc; Biomimetics; Drug Carriers; Hydrogen-Ion Concentration
PubMed: 38882544
DOI: 10.2147/IJN.S462480 -
ACS Omega Jun 2024Engineered artificial minerals (EnAMs) are the core of a new concept of designing scavenger compounds for the recovery of critical elements from slags. It requires a...
Engineered artificial minerals (EnAMs) are the core of a new concept of designing scavenger compounds for the recovery of critical elements from slags. It requires a fundamental understanding of solidification from complex oxide melts. Ion diffusivity and viscosity play vital roles in this process. In the melt, phase separations and ion transport give rise to gradients/increments in composition and, with it, to ion diffusivity, temperature, and viscosity. Due to this complexity, solidification phenomena are yet not well understood. If the melt is understood as increments of simple composition on a microscopic level, then the properties of these are more easily accessible from models and experiments. Here, we obtain these data for three stoichiometric lithium aluminum oxides. LiAlO is a promising EnAM for the recovery of lithium from lithium-ion battery pyrometallurgical processing. It is obtained through the addition of aluminum to the recycling slag melt. The high temperature properties spanning from below to above the liquidus temperature of three stoichiometric Li-Al-Oxides: LiAlO, LiAlO, and LiAlO are determined using molecular dynamic simulations. The compounds are also synthesized via the sol-gel route. The Li ion exhibits the largest diffusivity. They are quite mobile already below the liquidus temperature, i.e., for LiAlO at = 1700 K, the diffusion coefficient of the lithium ion equals = 3.0 × 10 m s. The other ions Al and O do not move considerably at that temperature. The diffusivity of Li is largest in the lithium-rich compound LiAlO with = 32 × 10 m s at 2500 K. The lower the viscosity, the higher the lithium content. The LiAlO exhibits a viscosity of η = 2.2 mPa s at 1328 K which matches well with the experimentally determined 2.5 mPa s at this temperature. The viscosity of LiAlO at 1800 K is more than two times higher. These data sets can help to describe the melts on a microscopic level and understand how the melt properties will change due to gradients in the Li/Al concentration.
PubMed: 38882149
DOI: 10.1021/acsomega.4c00723 -
Scientific Reports Jun 2024The purpose of this research was to examine the potential effects of bentonite (BN) supplemented diets on growth, feed utilization, blood biochemistry, and...
Bentonite-supplemented diets improved fish performance ammonia excretion haemato-biochemical analyses immunity antioxidants and histological characteristics of European seabass Dicentrarchus labrax.
The purpose of this research was to examine the potential effects of bentonite (BN) supplemented diets on growth, feed utilization, blood biochemistry, and histomorphology of Dicentrarchus labrax. Six treatments in triplicate were tested: B0, B0.5, B1.0, B1.5, B3.0, and B4.5, which represented fish groups fed diets supplemented with 0, 0.5, 1, 1.5, 3, and 4.5% BN, respectively. For 84 days, juveniles' seabass (initial weight = 32.73 g) were fed diets containing 46% protein, three times daily at 3% of body weight. With a 5% daily water exchange, underground seawater (32 ppt) was used. Findings revealed significant improvements in water quality (TAN and NH3), growth (FW, WG and SGR) and feed utilization (FCR, PER and PPV) in fish fed BN-supplemented diets, with the best values in favor of the B1.5 group. Additional enhancements in kidney function indicators (urea and uric acid) and liver enzymes were observed in fish of the BN-treated groups along with a decrease in cholesterol level in the B1.5 group. Further improvements in fish innate immunity (hemoglobin, red blood cells, glucose, total protein, globulin, and immunoglobulin IgM), antioxidant activity (total antioxidative capacity and catalase), and decreased cortisol levels in fish of the BN-treated groups. Histological examinations of the anterior and posterior intestines and liver in groups B1.5 and B3 revealed the healthiest organs. This study recommends BN at a concentration of 1.5% as a feed additive in the Dicentrarchus labrax diet.
Topics: Animals; Bass; Antioxidants; Dietary Supplements; Bentonite; Ammonia; Animal Feed; Diet
PubMed: 38879696
DOI: 10.1038/s41598-024-63936-6 -
Water Science and Technology : a... Jun 2024This paper centers on the preparation and characterization of both a clay support and a faujasite zeolite membrane. Additionally, the study explores the development of...
This paper centers on the preparation and characterization of both a clay support and a faujasite zeolite membrane. Additionally, the study explores the development of bacterial media to assess the performance of these prepared membranes. The faujasite zeolite membrane was created using the hydrothermal method, involving the deposition of a faujasite layer to fine-tune the pore sizes of the clay support. The clay supports were crafted from clay which was sieved to particle size Φ ≤ 63 μm, and compacted with 3.0 wt.% activated carbon, then sintered at 1,000 °C. Distilled water fluxes revealed a decrease from 1,500 L m h to a minimum of 412 L m h after 180 min of filtration. Both membranes were characterized by XRF, XRD, FTIR, adsorption-desorption of nitrogen (N), and SEM-EDS. PCR technique was used for the identification of the isolated sp., and the retention of the bacteria on the clay support and the faujasite zeolite membrane were found to be 96 and 99%, respectively. The results showed that the faujasite zeolite membrane passed the clay support due to a narrow pore size of the faujasite zeolite membrane of 2.28 nm compared to 3.55 nm for the clay supports.
Topics: Zeolites; Arthrobacter; Wastewater; Membranes, Artificial; Filtration; Water Purification
PubMed: 38877622
DOI: 10.2166/wst.2024.175 -
Planta Medica Jun 2024Corydalis yanhusuo(YHS), a traditional Chinese medicine, is widely used to treat various pains, and its active ingredient is alkaloids. This study aimed to develop a new...
Corydalis yanhusuo(YHS), a traditional Chinese medicine, is widely used to treat various pains, and its active ingredient is alkaloids. This study aimed to develop a new type of transdermal gel plaster containing the extract of Corydalis yanhusuo. Studies have shown that Fu'cupping physical permeation-enhancing techniques(FCPT) can promote the penetration of alkaloids and improve the efficacy of drugs. A transdermal gel plaster containing the extract of YHS was prepared and optimized using an orthogonal experimental design. The skin permeation ability of the gel plaster was studied in vitro, while the anti-inflammatory and analgesic effects of the prepared patch alone or with FCPT were evaluated in a rat model. The formulation of a gel plaster containing YHS extract was successfully prepared, with an optimized composition consisting of glycerin (15 g), sodium polyacrylate (2 g), silicon dioxide (0.3 g), ethanol (2 g), aluminum oxide (0.1 g), citric acid (0.05 g), the YHS extract (3 g) and water (15 g). The cumulative transdermal permeation of dehydrocorydaline, corypalmine, tetrahydropalmatine, and corydaline in 24 h was estimated to be, respectively, 569.7±63.2, 74.5±13.7, 82.4±17.2, and 38.9±8.1 μg/cm2. The in vitro diffusion dehydrocorydaline and corydaline followed the zero order kinetics profile, while that of corypalmine and tetrahydropalmatine followed a Higuchi equation. The prepared gel plaster significantly reduced paw swelling, down regulated inflammatory cytokines, and mitigated pain induced by mechanical or chemical stimuli. FCPT further improved the anti-inflammatory and analgesic effects of the patch. The combined application of FCPT and the alkaloid gel plaster may be effective against inflammation and pain.
PubMed: 38876472
DOI: 10.1055/a-2344-8841 -
ACS Applied Materials & Interfaces Jun 2024Plasmonic hot-electron-based photodetectors (HEB-PDs) have received widespread attention for their ability to realize effective carrier collection under sub-bandgap...
Plasmonic hot-electron-based photodetectors (HEB-PDs) have received widespread attention for their ability to realize effective carrier collection under sub-bandgap illumination. However, due to the low hot electron emission probability, most of the existing HEB-PDs exhibit poor responsivity, which significantly restricts their practical applications. Here, by employing the binary-pore anodic alumina oxide template technique, we proposed a compact plasmonic bound state in continuum metasurface-semiconductor-metal-based (BIC M-S-M) HEB-PD. The symmetry-protected BIC can manipulate a strong gap surface plasmon in the stacked M-S-M structure, which effectively enhances light-matter interactions and improves the photoresponse of the integrated device. Notably, the optimal M-S-M HEB-PD with near-unit absorption (∼90%) around 800 nm delivers a responsivity of 5.18 A/W and an IPCE of 824.23% under 780 nm normal incidence (1 V external bias). Moreover, the ultrathin feature of BIC M-S-M (∼150 nm) on the flexible substrate demonstrates excellent stability under a wide range of illumination angles from -40° to 40° and at the curvature surface from 0.05 to 0.13 mm. The proposed plasmonic BIC strategy is very promising for many other hot-electron-related fields, such as photocatalysis, biosensing, imaging, and so on.
PubMed: 38874560
DOI: 10.1021/acsami.4c03770 -
Nanoscale Jun 2024Nanoparticles have emerged as promising theranostic tools for biomedical applications, notably in the treatment of cancers. However, to fully exploit their potential, a...
Nanoparticles have emerged as promising theranostic tools for biomedical applications, notably in the treatment of cancers. However, to fully exploit their potential, a thorough understanding of their biodistribution is imperative. In this context, we prepared radioactive [Cu]-exchanged faujasite nanosized zeolite ([Cu]-FAU) to conduct positron emission tomography (PET) imaging tracking in preclinical glioblastoma models. results revealed a rapid and gradual accumulation over time of intravenously injected [Cu]-FAU zeolite nanocrystals within the brain tumor, while no uptake in the healthy brain was observed. Although a specific tumor targeting was observed in the brain, the kinetics of uptake into tumor tissue was found to be dependent on the glioblastoma model. Indeed, our results showed a rapid uptake in U87-MG model while in U251-MG glioblastoma model tumor uptake was gradual over the time. Interestingly, a [Cu] activity, decreasing over time, was also observed in organs of elimination such as kidney and liver without showing a difference in activity between both glioblastoma models. analyses confirmed the presence of zeolite nanocrystals in brain tumor with detection of both Si and Al elements originated from them. This radiolabelling strategy, performed for the first time using nanozeolites, enables precise tracking through PET imaging and confirms their accumulation within the glioblastoma. These findings further bolster the potential use of zeolite nanocrystals as valuable theranostic tools.
Topics: Animals; Zeolites; Positron-Emission Tomography; Copper Radioisotopes; Humans; Tissue Distribution; Mice; Cell Line, Tumor; Glioblastoma; Brain Neoplasms; Nanoparticles; Mice, Nude
PubMed: 38874227
DOI: 10.1039/d3nr05947b -
Small (Weinheim An Der Bergstrasse,... Jun 2024Energy-efficient glass windows are pivotal in modern infrastructure striving toward the "Zero energy" concept. Electrochromic (EC) energy storage devices emerge as a...
Energy-efficient glass windows are pivotal in modern infrastructure striving toward the "Zero energy" concept. Electrochromic (EC) energy storage devices emerge as a promising alternative to conventional glass, yet their widespread commercialization is impeded by high costs and dependence on external power sources. Addressing this, redox potential-based self-powered electrochromic (RP-SPEC) devices are introduced leveraging established EC materials like tungsten oxide (WO) and vanadium-doped nickel oxide (V-NiO) along with aluminum (Al) as an anode. These devices produce open circuit voltages (OCV) exceeding ±0.3 V, enabling autonomous operation for multiple cycles. The WO film exhibits 1% transmission and 88% modulation in the colored state at 550 nm with a mere 260 nm thickness. The redox interactions facilitate coloring and bleaching cycles without external power, while photo-charging rejuvenates the system. Notably, the inherent voltages of the RP-SPEC device offer dual functionality, powering electronic devices for up to 81 h. Large-area (≈28 cm) device feasibility is demonstrated, paving the way for industrial adoption. The RP-SPEC device promises to revolutionize smart window technology by offering both energy efficiency and autonomous operation, thus advancing sustainable infrastructure.
PubMed: 38874058
DOI: 10.1002/smll.202403156 -
ACS Applied Materials & Interfaces Jun 2024The development of growth factor-free biomaterials for bone tissue regeneration with anti-infection and anti-inflammatory activities remains challenging. Black...
The development of growth factor-free biomaterials for bone tissue regeneration with anti-infection and anti-inflammatory activities remains challenging. Black phosphorus nanosheets (BPNs), with distinctive attributes, including photothermal conversion and calcium ion chelation, offer potential for use in bone tissue engineering and infection prevention. However, BPNs are prone to oxidation and degradation in aqueous environments, and methods to stabilize BPNs for long-term bone repair remain insufficient. Herein, zeolitic imidazolate framework-8 (ZIF-8) was used to stabilize BPNs via in situ crystallization onto the surface of BPNs (BP@ZIF-8 nanocomposite). A novel injectable dual-component hydrogel comprising gelatin methacryloyl (GelMA) and methacrylate-modified hyaluronic acid (HAMA) was used as a BP@ZIF-8 nanocomposite carrier (GelMA/HAMA/BP@ZIF-8). The BP@ZIF-8 nanocomposite could effectively protect internal BPNs from oxidation and enhance the long-term photothermal performance of the hydrogel in both in vitro and in vivo settings. The GelMA/HAMA/BP@ZIF-8 hydrogel was injectable and exhibited outstanding performance for photothermal conversion, mechanical strength, and biodegradability, as well as excellent photothermal antibacterial activity against and in vitro and in an in vivo rat model. The GelMA/HAMA/BP@ZIF-8 hydrogel also provided a microenvironment conducive to osteogenic differentiation, promoting the transformation of M2 macrophages and inhibiting inflammatory responses. Furthermore, the hydrogel promoted bone regeneration and had a synergistic effect with near-infrared irradiation in a rat skull-defect model. Transcriptome sequencing analysis revealed that the PI3K-AKT- and calcium-signaling pathways may be involved in promoting osteogenic differentiation induced by the GH-BZ hydrogel. This study presents an innovative, multifaceted solution to the challenges of bone tissue regeneration with antibacterial and anti-inflammatory effects, providing insights into the design of smart biomaterials with dual therapeutic capabilities.
Topics: Anti-Bacterial Agents; Hydrogels; Animals; Osteogenesis; Phosphorus; Escherichia coli; Staphylococcus aureus; Rats; Zeolites; Gelatin; Mice; Hyaluronic Acid; Rats, Sprague-Dawley; Methacrylates; Microbial Sensitivity Tests; Metal-Organic Frameworks; Nanocomposites; RAW 264.7 Cells; Bone Regeneration; Nanostructures
PubMed: 38872401
DOI: 10.1021/acsami.4c05298