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JAAD International Dec 2023
PubMed: 37786789
DOI: 10.1016/j.jdin.2023.08.015 -
Cureus Sep 2023Neonatal alloimmune thrombocytopenia (NAIT) is a complex condition, stemming from the transplacental passage of alloantibodies from a pregnant mother directed against...
Neonatal alloimmune thrombocytopenia (NAIT) is a complex condition, stemming from the transplacental passage of alloantibodies from a pregnant mother directed against fetal platelet antigens. This case report discusses a rare instance of severe NAIT initially presenting as inadequate weight gain. After a clinical workup yielded negative findings for an infection and the resolution of the patient's thrombocytopenia following the administration of platelet products and intravenous immunoglobulin (IVIG), hematology deduced that this patient's NAIT was secondary to maternal history of gestational pemphigus. We describe the pathophysiology and current understanding of NAIT, pemphigoid gestationis (PG), as well as an analysis of their association. This intersection of NAIT and maternal PG underscores the importance of considering potential interactions between maternal autoimmune conditions overall and their impact on fetal health.
PubMed: 37692187
DOI: 10.7759/cureus.44946 -
American Journal of Obstetrics &... Sep 2023
Use of a pregnancy dermatology clinical scoring system to differentiate between pemphigoid gestationis and polymorphic eruption of pregnancy: practical considerations for the obstetrician.
Topics: Pregnancy; Female; Humans; Pemphigoid Gestationis; Obstetricians; Dermatology; Pregnancy Complications
PubMed: 37399893
DOI: 10.1016/j.ajogmf.2023.101078 -
Human Pathology Oct 2023Pathologists provide valuable input in the dermatological care of pregnant patients in various contexts. This article provides dermatopathology updates on cutaneous...
Pathologists provide valuable input in the dermatological care of pregnant patients in various contexts. This article provides dermatopathology updates on cutaneous changes associated with pregnancy, organized based on the following classification system: physiological skin changes in pregnancy, specific dermatoses of pregnancy, dermatoses modified in pregnancy, and skin neoplasms in pregnancy. Awareness of the impact of pregnancy on the skin by pathologists is important, as this is an opportunity to contribute to diagnostic precision in this patient population.
PubMed: 37209919
DOI: 10.1016/j.humpath.2023.05.005 -
Journal of the European Academy of... Sep 2023
Topics: Pregnancy; Female; Humans; Pemphigoid Gestationis; Antibodies, Monoclonal, Humanized; Pemphigoid, Bullous
PubMed: 37147906
DOI: 10.1111/jdv.19171