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Long-term health-related quality of life in meningioma survivors: A mixed-methods systematic review.Neuro-oncology Advances 2024Meningiomas account for ~25% of all primary brain tumors. These tumors have a relatively favorable prognosis with ~92% of meningioma patients surviving >5 years after...
BACKGROUND
Meningiomas account for ~25% of all primary brain tumors. These tumors have a relatively favorable prognosis with ~92% of meningioma patients surviving >5 years after diagnosis. Yet, patients can report high disease burden and survivorship issues even years after treatment, affecting health-related quality of life (HRQOL). We aimed to systematically review the literature and synthesize evidence on HRQOL in meningioma patients across long-term survival, defined as ≥2 years post-diagnosis.
METHODS
Systematic literature searches were carried out using Medline, EMBASE, CINAHL, PsycINFO, and Web of Science Core Collection. Any published, peer-reviewed articles with primary quantitative, qualitative, or mixed-methods data covering the physical, mental, and/or social aspects of HRQOL of meningioma survivors were included. A narrative synthesis method was used to interpret the findings.
RESULTS
Searches returned 2253 unique publications, of which 21 were included. Of these, = 15 involved quantitative methodology, = 4 mixed methods, and = 2 were qualitative reports. Patient sample survival ranged from 2.75 to 13 years. HRQOL impairment was seen across all domains. issues included persevering symptoms (eg, headaches, fatigue, vision problems); issues comprised emotional burden (eg, high prevalence of depressive symptoms and anxiety) and cognitive complaints; issues included role limitations, social isolation, and affected work productivity. Due to study heterogeneity, the impact of treatment on long-term HRQOL remains unclear.
CONCLUSIONS
The findings from this review highlight the areas of HRQOL that can be impacted in long-term survivorship for patients with meningioma. These findings could help raise awareness among clinicians and patients, facilitating support provision.
PubMed: 38375359
DOI: 10.1093/noajnl/vdae007 -
Frontiers in Psychiatry 2023Depression is a common mental illness that is widely recognized by its lack of pleasure, fatigue, low mood, and, in severe cases, even suicidal tendencies....
BACKGROUND
Depression is a common mental illness that is widely recognized by its lack of pleasure, fatigue, low mood, and, in severe cases, even suicidal tendencies. Photobiomodulation (PBM) is a non-invasive neuromodulation technique that could treat patients with mood disorders such as depression.
METHODS
A systematic search of ten databases, including randomized controlled trials (RCTs) for depression, was conducted from the time of library construction to September 25, 2023. The primary outcome was depression. The secondary outcome was sleep. Meta-analysis was performed using RevMan (version 5.4) and Stata (version 14.0). Subgroup analyses were performed to identify sources of heterogeneity. The certainty of the evidence was assessed using the Grading of Recommendations Assessment, Development, and Evaluation (GRADE).
RESULTS
Three thousand two hundred and sixty-five studies were retrieved from the database and screened for inclusion in eleven trials. The forest plot results demonstrated that PBM alleviated depression (SMD = -0.55, 95% CI [-0.75, -0.35], = 46%). But it is not statistically significant for patients' sleep outcomes (SMD = -0.82, 95% CI [-2.41, 0.77], = 0%, > 0.05). Subgroup analysis showed that s-PBM was superior to t-PBM in relieving symptoms of depression. The best improvement for t-PBM was achieved using a wavelength of 823 nm, fluence of 10-100 J/cm, irradiance of 50-100 mW/cm, irradiance time of 30 min, treatment frequency < 3/week, and number of treatments >15 times. The best improvement for s-PBM was achieved using a wavelength of 808 nm, fluence ≤1 J/cm, irradiance of 50-100 mW/cm, irradiance time ≤ 5 min, treatment frequency ≥ 3/week, number of treatments >15 times. All results had evidence quality that was either moderate or very low, and there was no bias in publication.
CONCLUSION
We conclude that PBM is effective in reducing depression symptoms in patients. However, the current number of studies is small, and further studies are needed to extend the current analysis results.
SYSTEMATIC REVIEW REGISTRATION
https://www.crd.york.ac.uk/PROSPERO/, CRD42023444677.
PubMed: 38356614
DOI: 10.3389/fpsyt.2023.1267415 -
American Journal of Public Health Feb 2024Mental health is declining in health care workers. To provide a comprehensive assessment of intervention literature focused on the support and treatment of mental...
Mental health is declining in health care workers. To provide a comprehensive assessment of intervention literature focused on the support and treatment of mental health within the health care workforce. We searched online databases (e.g., Medline, PsycINFO). We selected manuscripts published before March 2022 that evaluated the target population (e.g., nurses), mental health outcomes (e.g., burnout, depression), and intervention category (e.g., mindfulness). Of 5158 publications screened, 118 interventions were included. We extracted relevant statistics and information. Twenty (17%) earned study quality ratings indicating design, analysis, and implementation strengths. Randomized controlled trials were used by 52 studies (44%). Thirty-eight percent were conducted in the United States (n = 45). Ninety (76%) reported significant changes, and 46 (39%) reported measurable effect sizes. Multiple interventions significantly reduced stress (n = 29; 24%), anxiety (n = 20; 17%), emotional exhaustion or compassion fatigue (n = 16; 14%), burnout (n = 15; 13%), and depression (n = 15; 13%). Targeted, well-designed mental health interventions can improve outcomes among health care workers. Targeted health care‒focused interventions to address workers' mental health could improve outcomes within this important and vulnerable workforce. (. 2024;114(S2):S213-S226. https://doi.org/10.2105/AJPH.2023.307556).
Topics: Humans; Mental Health; Evidence-Based Medicine; Health Personnel; Anxiety; Delivery of Health Care
PubMed: 38354343
DOI: 10.2105/AJPH.2023.307556 -
BMC Psychology Feb 2024The deleterious effects of mental fatigue (MF) on athletes have been carefully studied in various sports, such as soccer, badminton, and swimming. Even though many...
The deleterious effects of mental fatigue (MF) on athletes have been carefully studied in various sports, such as soccer, badminton, and swimming. Even though many researchers have sought ways to ameliorate the negative impact of MF, there is still a lack of studies that review the interventions used to counteract MF among athletes. This review aims to report the current evidence exploring the effects of interventions on MF and sport-specific performance, including sport-specific motor performance and perceptual-cognitive skills. Web of Science, Scopus, PubMed, and SPORTDicus (EBSCOhost) were combed through to find relevant publications. Additionally, the references and Google Scholar were searched for any grey literature. For the current review, we included only randomized controlled trials that involved athletes, a primary task to induce MF, interventions to counter MF with comparable protocols, and the outcomes of sport-specific motor performance and perceptual-cognitive skill. The selection criteria resulted in the inclusion of 10 articles. The manipulations of autonomous self-control exertion, person-fit, nature exposure, mindfulness, and transactional direct current stimulation showed that positive interventions counteract MF and improve sport-specific performance in different domains, including strength, speed, skill, stamina, and perceptual-cognitive skills. The selected interventions could significantly counteract MF and improve subsequent sport-specific performance. Moreover, self-regulation and attention resources showed the importance of the potential mechanisms behind the relevant interventions.
Topics: Humans; Sports; Athletes; Soccer; Mental Fatigue
PubMed: 38336843
DOI: 10.1186/s40359-023-01476-w -
EClinicalMedicine Feb 2024Post Coronavirus disease (COVID) and other post-viral infection syndromes present an overlap of pathogenesis, onset, progression, and symptom profile. We aimed to...
BACKGROUND
Post Coronavirus disease (COVID) and other post-viral infection syndromes present an overlap of pathogenesis, onset, progression, and symptom profile. We aimed to systematically describe studies on post-viral conditions and determine the entity of post COVID compared to other post-viral conditions in children.
METHODS
We conducted a systematic search of the Embase, MEDLINE, Cochrane Library, and GoogleScholar databases (January 1946-3 November 2023), according to the Preferred Reporting Items for Systematic reviews and Meta-Analyses (PRISMA) guidelines. The main outcomes were differences in condition duration, symptom type, and development of chronic symptoms. This systematic review was registered on PROSPERO (CRD42023401789).
FINDINGS
35/5051 studies were included, with 42,934 children, adolescents and young adults (0-20 years old) overall. Twenty-eight studies focused on post COVID symptoms, followed by five papers on Respiratory Syncytial Virus (RSV) and Rhinovirus, one study on Epstein-Barr Virus (EBV), and one on gastrointestinal viruses. Studies on post COVID mainly reported data on older children/adolescents, describing long-lasting symptoms, including fatigue, neurologic, cardiorespiratory, musculoskeletal, mental health, and gastrointestinal symptoms. The maximum described symptoms duration was eighteen months, with an average follow-up of seven months. The development of chronic symptoms was reported by 30 studies (93.8%) for 10,473/28,474 patients (36.8%). Recovery was achieved in 18,001/28,474 cases (63.2%). The study on EBV reported persistent fatigue in adolescents for a similar duration (6 months, 46% chronic). Studies on RSV and Rhinovirus were mainly done in children under three years, with development of recurrent wheezing (up to 3 years).
INTERPRETATION
Post-viral fatigue was a shared feature between post COVID and post EBV conditions. A better understanding of post COVID as a unique condition, sharing features with other post-viral syndromes, is needed. The healthcare burden and socio-economic consequences for children and their families warrant further investigation and development of appropriate healthcare management plans. The foremost requirement is the establishment of consistent and shareable definitions, as well as a consensus on outcomes, to effectively evaluate follow-up and quantify the burden of different viral infections.
FUNDING
EU Horizon, EDCTP, NIH.
PubMed: 38333536
DOI: 10.1016/j.eclinm.2024.102436 -
PloS One 2024The construction industry is recognized as one of the most hazardous industries globally due to the dynamic on site activities and labour-intensive characteristics. The...
The construction industry is recognized as one of the most hazardous industries globally due to the dynamic on site activities and labour-intensive characteristics. The construction tasks are physically and cognitively demanding therefore the construction workers are prone to work fatigue which compromises safety performance. The evaluation of fit for duty, or fitness for work (FFW) aims to determine if workers are at risk of adverse impacts of ill-health, injury or accidents. This systematic review aimed to critically summarize up-to-date measures and evaluation tools that were employed to monitor work fitness or fatigue specifically among construction workers. Adhering with the PRISMA protocol, three databases were searched from the inception to 2022, with a total combination of 37 keywords, concluding to the selection of 20 relevant articles. The Mixed Method Appraisal Tool (MMAT) was used as the guide for the study appraisal. A total of 20 articles were reviewed, published from 2008-2022. Majority of the studies employed experimental design. The review identified the subjective evaluation scales and objective measurement tool. The subjective self-response questionnaires can be categorized into single dimension or multidimension covering both physical and mental fitness; whereas the objective measurement tool can be categorized into physiological metrics, physical and cognitive performance measure. The available scientific evidence has raised the relevant issues for on-site practicality and potentially guide the formulation of evidence-based guidelines for the FFW assessment in the construction industry.
Topics: Humans; Construction Industry; Surveys and Questionnaires; Research Design; Physical Examination; Fatigue
PubMed: 38324557
DOI: 10.1371/journal.pone.0287892 -
Supportive Care in Cancer : Official... Jan 2024The purpose of this study was to systematically review the literature on the association between adverse childhood events (ACEs) and mental health problems in cancer... (Review)
Review
PURPOSE
The purpose of this study was to systematically review the literature on the association between adverse childhood events (ACEs) and mental health problems in cancer survivors.
METHODS
This review was conducted in line with PRISMA (Preferred Reporting Items for Systematic Reviews and Meta-Analyses) guidelines. Four databases (PubMed, PsychINFO, Web of Science, and Cochrane) were searched on 27-08-2023.
RESULTS
Of the 1413 references yielded by the literature search, 25 papers met inclusion criteria and were reviewed. Most studies were performed in the USA, most included breast cancer survivors, and the number of included participants ranged between 20 and 1343. ACEs were relatively prevalent, with self-report rates ranging between 40 and 95%. Having been exposed to ACEs was a risk factor for heightened levels of emotional distress, anxiety, depressive symptoms, and fatigue during cancer treatment. Results varied depending on the variables included, and per subscale, but were consistent across different cultures and heterogenous patient groups.
CONCLUSION
The association between ACE and mental health outcomes was significant in most studies. In order to improve treatment for this vulnerable population, it may be necessary to screen for ACEs before cancer treatment and adjust treatment, for example, by means of trauma-informed care (TIC), which recognizes and responds to the impact of trauma on individuals seeking healthcare.
Topics: Child; Humans; Cancer Survivors; Mental Health; Survivors; Anxiety; Anxiety Disorders; Neoplasms
PubMed: 38175303
DOI: 10.1007/s00520-023-08280-7 -
Pediatric Research Mar 2024With the Experience Sampling Method (ESM) participants are asked to provide self-reports of their symptoms, feelings, thoughts and behaviours in daily life. This...
BACKGROUND
With the Experience Sampling Method (ESM) participants are asked to provide self-reports of their symptoms, feelings, thoughts and behaviours in daily life. This preregistered systematic review assessed how ESM is being used to monitor emotional well-being, somatic health, fatigue and pain in children and adolescents with a chronic somatic illness.
METHODS
Databases were searched from inception. Studies were selected if they included children or adolescents aged 0-25 years with a chronic somatic illness and used ESM focussing on mental health or psychosocial wellbeing, biopsychosocial factors and/or somatic health. Two reviewers extracted data of the final 47 papers, describing 48 studies.
RESULTS
Most studies evaluated what factors influence medical or psychological symptoms and how symptoms influence each other. Another common purpose was to study the feasibility of ESM or ESM as part of an app or intervention. Study methods were heterogeneous and most studies lack adequate reporting of ESM applications and results.
CONCLUSIONS
While ESM holds great potential for providing results and feedback to patients and caregivers, little use is being made of this option. Future studies should consider what they report in their studies, conduct a priori power analyses and how ESM can be embedded in clinical practice.
IMPACT
While ESM has many clinical applications, it is currently mostly used for research purposes. Current studies using ESM are heterogeneous and lack consistent, high-quality reporting. There is great potential in ESM for providing patients and parents with personalised feedback.
Topics: Adolescent; Humans; Child; Ecological Momentary Assessment; Emotions; Mental Health; Self Report; Delivery of Health Care
PubMed: 38062256
DOI: 10.1038/s41390-023-02918-2 -
Biological Psychology Jan 2024Fatigue-specific changes in the autonomic nervous system are often assumed to underlie the development of mental fatigue caused by prolonged cognitive tasks (i.e....
Fatigue-specific changes in the autonomic nervous system are often assumed to underlie the development of mental fatigue caused by prolonged cognitive tasks (i.e. Time-on-Task). Therefore, several previous studies have chosen to investigate the Time-on-Task related changes in heart rate variability (HRV). However, previous studies have used many different HRV indices, and their results often show inconsistencies. The present study, therefore, systematically reviewed previous empirical HRV studies with healthy individuals and in which mental fatigue is induced by prolonged cognitive tasks. Articles relevant to the objectives were systematically searched and selected by applying the PRISMA guidelines. We screened 360 records found on 4 databases and found that 19 studies were eligible for full review in accordance with the inclusion criteria. In general, all studies reviewed (with the exception of two studies) found significant changes in HRV with increasing Time-on-Task, suggesting that HRV is a reliable autonomic marker for Time-on-Task induced fatigue. The most conclusive HRV indices that showed a consistent Time-on-Task effect were the low frequency component of HRV and the time domain indices, particularly the root mean square of successive differences. Time-on-Task typically induced an increasing trend in both type of measures.
Topics: Humans; Autonomic Nervous System; Heart Rate; Mental Fatigue
PubMed: 38056707
DOI: 10.1016/j.biopsycho.2023.108727 -
Frontiers in Human Neuroscience 2023Fatigue is a serious challenge when applying a steady-state visual evoked potential (SSVEP)-based brain-computer interfaces (BCIs) in the real world. Many researchers...
BACKGROUND
Fatigue is a serious challenge when applying a steady-state visual evoked potential (SSVEP)-based brain-computer interfaces (BCIs) in the real world. Many researchers have used quantitative indices to study the effect of visual stimuli on fatigue. According to a wide range of studies in fatigue analysis, there are contradictions and inconsistencies in the behavior of fatigue indicators.
NEW METHOD
In this study, for the first time, a systematic review and meta-analysis were performed on fatigue indices and fatigue caused by stimulation paradigm. We queried three scientific search engines for studies published between 2000 and 2022. The inclusion criteria were papers investigating mental and visual fatigue from performing a visual task using electroencephalogram (EEG) signals.
RESULTS
Attractiveness and variation are the most effective ways to reduce BCI fatigue. Therefore, zoom motion, Newton's ring motion, and cue patterns reduce fatigue. While the color of the cue could effectively reduce fatigue, its shape and background had no effect on fatigue. Additionally, the questionnaire and quantitative indicators such as frequency indices, signal-to-noise ratio (SNR), SSVEP amplitude, and multiscale entropy were utilized to assess fatigue. Meta-analysis indicated that when a person is fatigued, the spectrum amplitude of alpha, theta, and increase significantly, while SNR and SSVEP amplitude decrease significantly.
CONCLUSION
The outcomes of this study can be used to design more optimal stimulation protocols that cause less fatigue. Moreover, the level of fatigue can be quantitatively assessed with indicators without the participant's self-reports.
PubMed: 38053651
DOI: 10.3389/fnhum.2023.1248474