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Expert Reviews in Molecular Medicine Aug 2023Metallic nanoparticles from different natural sources exhibit superior therapeutic options as compared to the conventional methods. species have attracted special... (Review)
Review
BACKGROUND
Metallic nanoparticles from different natural sources exhibit superior therapeutic options as compared to the conventional methods. species have attracted special attention of researchers worldwide due to the presence of bioactive molecules such as flavonoids, biflavonoids, triterpenes, steroids, saponins, tannins and other secondary metabolites that exhibit antimicrobial, antiplasmodial, anticancer and anti-inflammatory activities. Environment friendly green synthesised silver nanoparticles from species provide viable, safe and efficient treatment against different fungal pathogens.
OBJECTIVE
This systematic review aims to summarise the literature pertaining to superior antifungal ability of green synthesised silver nanoparticles using plant extracts of spp. in comparison to both aqueous and ethanolic raw plant extracts by electronically collecting articles from databases.
METHODS
The recommendations of the Preferred Reporting Items for Systematic Reviews and Meta-Analysis were taken into consideration while preparing this review. The titles and abstracts of the collected data were stored in Endnote20 based on the inclusion and exclusion criteria. The search strategy included literature from established sources like PubMed, Google Scholar and Retrieval System Online using subject descriptors.
RESULTS
The search yielded 60 articles with unique hits. After removal of duplications, 46 articles were identified, 40 were assessed and only seven articles were chosen and included in this review based on our eligibility criteria.
CONCLUSION
The physicochemical and preliminary phytochemical investigations of suggest higher drug potency of nanoparticles synthesised from plant extract against different diseases as compared to aqueous and ethanolic plant extracts. The study holds great promise as the synthesis of nanoparticles involves low energy consumption, minimal technology and least toxic effects.
Topics: Humans; Metal Nanoparticles; Selaginellaceae; Silver; Anti-Infective Agents; Plant Extracts
PubMed: 37534437
DOI: 10.1017/erm.2023.21