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Fine structure of the compound eyes of the crepuscular moth (Busck 1916) (Lepidoptera: Tortricidae).Frontiers in Physiology 2024Morphological organization, ultrastructure and adaptational changes under different light intensities (10000, 100, 1, and 0.01 mW/m) of the compound eye of the oriental...
Morphological organization, ultrastructure and adaptational changes under different light intensities (10000, 100, 1, and 0.01 mW/m) of the compound eye of the oriental fruit moth (Busck 1916) were investigated. Its superposition type of eyes consist of approximately 1072 ommatidia in males and 1029 ommatidia in females with ommatidial diameters of around 15 μm. Each ommatidium features a laminated corneal lens densely covered by corneal nipples of 256 nm in height. Crystalline cones are formed by four cone cells, proximally tapering to form a narrow crystalline tract with a diameter of 1.5 μm. Eight retinula cells, two primary and six secondary pigment cells per ommatidium are present. The 62.3 μm long rhabdom is divided into a thin 1.8 μm wide distal and a 5.2 μm wide proximal region. Distally the fused rhabdom consists of the rhabdomeres of seven retinula cells (R1-R7) and connects with the crystalline cone. In the proximal rhabdom region, the pigment-containing retinula cell R8 occupies a position in centre of the rhabdom while R1-R7 cells have taken peripheral positions. At this level each ommatidial group of retinula cells is surrounded by a tracheal tapetum. In response to changes from bright-light to dim-light adaptations, the pigment granules in the secondary pigment cells and retinula cells migrate distally, with a decrease in the length of crystalline tract.
PubMed: 38390450
DOI: 10.3389/fphys.2024.1343702 -
The Breast Journal 2024Mammoplasty is a surgery commonly used for macromastia. Many mammoplasty techniques are described, all with their specific pros and cons. However, the concern to avoid...
Mammoplasty is a surgery commonly used for macromastia. Many mammoplasty techniques are described, all with their specific pros and cons. However, the concern to avoid serious complications sometimes takes precedence, and the ideal result cannot be. For macromastia and severely ptotic breasts, usually the free nipple-areolar complex (NAC) mammoplasty technique is implemented. The results, however, may only be completely satisfactory regarding cosmetics. Loss of NAC, poor appearance, flabbiness, flattening, and ptosis are among the disadvantages of this technique. This study aimed to present the results of mammoplasty employing the superomedial pedicle technique without interrupting a macromastia central base with a pedicle length of 8 to 18 cm. According to the literature, many plastic surgeons recommend the free NAC rather than the pedicle technique because of the high complication rates in mammoplasties planned for highly ptotic breasts and macromastia. On the other hand, many free NAC techniques and their modifications with pedicle mammoplasty are described. The general conviction is that a standard method, protocol, or technique good for all patients does not exist. Our results are more acceptable both cosmetically and physiologically. Therefore, the superomedial pedicle technique can be modified to achieve ideal results where free NAC mammoplasty is considered for severe macromastia and ptotic patients. This combined method contributes to the viability of NAC by increasing blood supply to breast tissue and providing an ideal breast appearance.
Topics: Humans; Female; Treatment Outcome; Breast Neoplasms; Breast; Mammaplasty; Nipples; Retrospective Studies; Hypertrophy
PubMed: 38389976
DOI: 10.1155/2024/7635485 -
Cureus Jan 2024Breast sarcomatoid carcinoma, which are malignant tumors that form from the mesenchymal tissue of the mammary gland, are extremely uncommon and come in two varieties:...
Breast sarcomatoid carcinoma, which are malignant tumors that form from the mesenchymal tissue of the mammary gland, are extremely uncommon and come in two varieties: primary and secondary (development associated to therapy). Breast sarcomas are malignancies that are aggressive and have a bad prognosis. Multidisciplinary surgery, chemotherapy, and radiotherapy are among the treatment possibilities. This case report reports a case of 35-year-old female presented to our hospital with a palpable tumor in her right breast and pungent discharge from her nipples. These signs persisted for over five years. A sarcomatoid breast cancer was discovered by postoperative histology.
PubMed: 38384627
DOI: 10.7759/cureus.52696 -
Plastic and Reconstructive Surgery.... Feb 2024Superior pedicle breast reduction is a very popular technique among plastic surgeons. This technique has had many variations looking for fewer complications and better...
BACKGROUND
Superior pedicle breast reduction is a very popular technique among plastic surgeons. This technique has had many variations looking for fewer complications and better long-lasting results. The aim of this article is to present a novel technique of breast reduction, making variations in the design of the periareolar incision, using a superior pedicle with a constant vertical incision of 5 cm and a shortened horizontal incision.
METHODS
The superior pedicle inverted T-mammoplasty with a shortened horizontal scar technique was performed in 1200 patients who underwent surgery between 2010 and 2023; follow-up examination was carried out for an average of 1 year (3 months to 3 years). A patient satisfaction survey was conducted.
RESULTS
Patient satisfaction rate was 99%. There were no cases of total necrosis of the areola-nipple complex, 2.7% of the patients presented partial necrosis of the areola-nipple complex, 1.4% of the patients presented local infection, 1.7% presented dehiscence at some point of the vertical or horizontal suture, 4% of the patients presented a widened scar, 8% of the patients presented alteration in the sensibility of the areola-nipple complex, and 0.6% of the patients presented hematoma. With this technique, a rise of the areola-nipple complex of up to 22cm was achieved.
CONCLUSIONS
The superior pedicle inverted T-mammaplasty with shortened horizontal scar technique showed a lower number of surgical complications compared with other techniques previously used for breast reduction, even when applied in gigantomasty. It provides lasting results and a high rate of patient satisfaction.
PubMed: 38379778
DOI: 10.1097/GOX.0000000000005625 -
European Journal of Medical Research Feb 2024The aim of this study was to investigate risk factors for the severity of breast abscess during lactation.
OBJECTIVE
The aim of this study was to investigate risk factors for the severity of breast abscess during lactation.
METHODS
A cross-sectional study was conducted using data from the Questionnaire survey of breast abscess patients. According to whether the maximum abscess diameter > 5 cm, the patients were divided into two groups for univariate and multivariate regression analysis.
RESULTS
1805 valid questionnaires were included. Univariate and Binary logistic regression analysis demonstrated that low education (OR = 1.5, 95% CI 1.1-2.0, P = 0.005), non-exclusive breastfeeding (OR = 0.7, 95% CI 0.6-0.9, P = 0.004), fever > 37.5 ℃ (OR = 0.7, 95% CI 0.6-0.9, P = 0.003), flat or inverted nipples (OR = 0.7, 95% CI 0.6-0.9, P = 0.005), antibiotic used (OR = 0.7, 95% CI 0.6-0.9, P = 0.006), and non-medical massage (OR = 0.3, 95% CI 0.2-0.4, P < 0.001) were the effective independent influencing factors for the maximum breast abscess diameter > 5 cm.
CONCLUSION
Low education, non-exclusive breastfeeding, fever > 37.5 ℃, inverted or flat nipples, antibiotic used, and non-medical massage history have adverse effects on the severity of breast abscess during lactation.
Topics: Female; Humans; Breast Feeding; Abscess; Cross-Sectional Studies; Mastitis; Lactation; Anti-Bacterial Agents
PubMed: 38378627
DOI: 10.1186/s40001-024-01733-7 -
Journal of Cancer Research and... Oct 2023Primary rhabdomyosarcoma (RMS) of breast is a very rare malignancy usually affecting adolescent girls with a poor prognosis and no definitive treatment established....
Primary rhabdomyosarcoma (RMS) of breast is a very rare malignancy usually affecting adolescent girls with a poor prognosis and no definitive treatment established. Here, we report a case of a 17-year-old girl who presented to us operated for a right breast mass with histopathology suggestive of RMS. She had undergone wide local excision with nipple-areola complex along with axillary node dissection for positive nodes. Immunohistochemistry was done which showed tumor cells which were positive for desmin and myogenin and were negative for leukocyte common antigen, cluster of differentiation 34 (CD-34), and AE1/AE3 which confirmed the diagnosis of RMS. She was planned for adjuvant chemotherapy but refused taking treatment. Two months later, she presented with local site recurrence for which re-excision was done, and she was started on adjuvant chemotherapy with vincristine, Adriamycin, and cyclophosphamide regimen after metastatic workup. She then received radiation treatment following which she is at present under follow-up with no signs of disease until now.
Topics: Adolescent; Female; Humans; Breast Neoplasms; Rhabdomyosarcoma; Breast; Vincristine; Doxorubicin
PubMed: 38376322
DOI: 10.4103/jcrt.jcrt_1919_21 -
International Breastfeeding Journal Feb 2024Despite concerted efforts by policy developers, health professionals and lay groups, breastfeeding rates in Ireland remain one of the lowest in world, with 63.6% of...
BACKGROUND
Despite concerted efforts by policy developers, health professionals and lay groups, breastfeeding rates in Ireland remain one of the lowest in world, with 63.6% of mothers initiating breastfeeding at birth, dropping to 37.6% of mothers breastfeeding exclusively on hospital discharge. Nipple trauma and difficulties with baby latching are major contributors to the introduction of formula and discontinuation of breastfeeding. Research shows laid-back breastfeeding (LBBF) significantly reduces breast problems such as sore and cracked nipples, engorgement, and mastitis as well as facilitating a better latch. Although the benefits of LBBF are well documented, this position does not seem to be routinely suggested to mothers as an option when establishing breastfeeding. This study aims to determine midwives' and student midwives' knowledge, attitudes, and practices of using laid-back breastfeeding in Ireland.
METHOD
A cross-sectional descriptive survey distributed to midwives and student midwives in three maternity hospitals in Ireland and two online midwifery groups based in the Republic of Ireland, during June, July, and August 2021.
RESULTS
Two hundred and fifty-three valid responses were received from nine maternity units. Most participants (81.4%) were aware of laid-back breastfeeding. However, only 6.8% of respondents cited it as the position they most frequently use. Over one-third (38.34%) had never used this position with mothers. Those more likely to suggest LBBF had personal experience of it, were lactation consultants or working towards qualification, or had participated in specific education about LBBF. Barriers included lack of education, confidence, time, and experience. Further issues related to work culture, a tendency to continue using more familiar positions and concerns about mothers' anatomy and mothers' unfamiliarity with LBBF.
CONCLUSION
Although there was a high level of awareness of laid-back breastfeeding among midwives and student midwives, there are challenges preventing its use in practice. Education specifically related to using LBBF in practice is required to overcome the barriers identified. A greater understanding of mothers' and babies' intrinsic feeding capacities may give midwives more confidence to recommend this method as a first choice, potentially leading to more successful breastfeeding establishment and maintenance.
Topics: Infant; Infant, Newborn; Female; Humans; Pregnancy; Breast Feeding; Midwifery; Health Knowledge, Attitudes, Practice; Cross-Sectional Studies; Ireland; Students
PubMed: 38373983
DOI: 10.1186/s13006-024-00619-y -
Indian Journal of Pathology &... 2024This is a case report of a rare and uncommon primary invasive squamous cell carcinoma (SCC) of the nipple in a male patient. The patient presented with an ulcerated... (Review)
Review
This is a case report of a rare and uncommon primary invasive squamous cell carcinoma (SCC) of the nipple in a male patient. The patient presented with an ulcerated growth over the left nipple for the last 20 years, which progressed over the last 6 months. He underwent wide local excision with level II axillary lymph node dissection, and one out of 42 lymph nodes harvested showed metastatic deposit. The patient was planned for follow-up with no adjuvant treatment, and had no evidence of local-regional or distant recurrence at 24 months follow-up. The primary invasive SCC of male nipple is very rare, and its diagnosis is challenging as it can be confused with other clinical conditions. However, a histopathological examination with immunohistochemistry can differentiate primary SCC nipple from other differential diagnoses. The treatment options for cutaneous SCC include surgical excision, cryotherapy, electrosurgery, topical ointments, definitive radiation therapy, and photodynamic therapy. Regional lymph node dissection in SCC nipple could potentially have therapeutic and prognostic significance.
Topics: Adult; Humans; Male; Nipples; Carcinoma, Squamous Cell; Lymph Nodes; Lymph Node Excision; Prognosis
PubMed: 38358205
DOI: 10.4103/ijpm.ijpm_445_23 -
International Journal of Surgery... Apr 2024Due to the short operation time and no need for special instruments, reverse-sequence endoscopic nipple-sparing mastectomy (R-E-NSM) with direct-to-implant breast...
A novel technique of reverse-sequence endoscopic nipple-sparing mastectomy with direct-to-implant breast reconstruction: medium-term oncological safety outcomes and feasibility of 24-h discharge for breast cancer patients.
BACKGROUND
Due to the short operation time and no need for special instruments, reverse-sequence endoscopic nipple-sparing mastectomy (R-E-NSM) with direct-to-implant breast reconstruction (DIBR) has been rapidly becoming popular in the last three years. However, there has yet to be an evaluation of its oncologic safety or the feasibility of discharging patients within 24 h.
MATERIALS AND METHODS
In this single-centre retrospective cohort study, individuals diagnosed with stage 0-III breast cancer between May 2020 and April 2022 who underwent traditional open mastectomy or R-E-NSM with DIBR were included. Follow-up started on the date of surgery and ended in December 2023. Data, including demographics, tumour characteristics, medium-term oncological outcomes, and postoperative complications, were collected and analyzed. Propensity score matching (PSM) was performed to minimize selection bias.
RESULTS
This study included 1679 patients [median (IQR) age, 50 [44-57) years]. Of these, 344 patients underwent R-E-NSM with DIBR (RE-R group), and 1335 patients underwent traditional open mastectomy (TOM group). The median [IQR] follow-up time was 30 [24-36] months [29 (23-33) months in the RE-R group and 30([24-36) months in the TOM group]. Regarding before or after PSM, the P value of local recurrence-free survival (LRFS, 0.910 and 0.450), regional recurrence-free survival (RRFS, 0.780 and 0.620), distant metastasis-free survival (DMFS, 0.061 and 0.130), overall survival (OS, 0.260 and 0.620), disease-free survival (DFS, 0.120 and 0.330) were not significantly different between the RE-R group and the TOM group. The 3y-LRFS and 3y-DFS rates were 99.0% and 97.1% for the RE-R group and 99.5% and 95.3% for the TOM group, respectively. The rates of any complications and major complications were not significantly different between the RE-R patients who were discharged within 24 h and the RE-R patients who were not discharged within 24 h ( P =0.290, P =0.665, respectively) or the TOM patients who were discharged within 24 h ( P =0.133, P =0.136, respectively).
CONCLUSIONS
R-E-NSM with DIBR is an innovative oncologic surgical procedure that not only improves cosmetic outcomes but also ensures reliable oncologic safety and fewer complications, enabling patients to be safely discharged within 24 h. A long-term prospective multicenter assessment will be supporting.
Topics: Humans; Female; Middle Aged; Breast Neoplasms; Retrospective Studies; Adult; Nipples; Endoscopy; Feasibility Studies; Patient Discharge; Mastectomy; Mammaplasty; Postoperative Complications; Treatment Outcome
PubMed: 38348883
DOI: 10.1097/JS9.0000000000001134