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American Journal of Ophthalmology Case... Sep 2023To report a case of diffuse xanthogranuloma presenting as bilateral anterior uveitis in a neonate.
PURPOSE
To report a case of diffuse xanthogranuloma presenting as bilateral anterior uveitis in a neonate.
OBSERVATIONS
A neonate was brought by the parents with complaints of redness, watering, and photophobia in both eyes for 10 days. Examination under anesthesia revealed the presence of bilateral hyphema, fibrinous membrane, corneal haze, and raised intraocular pressure (IOP). Ultrasound Biomicroscopy revealed diffuse bilateral iris thickening. The child was managed medically with topical glaucoma medications, topical steroids, and cycloplegics. The child responded well with the resolution of hyphema, anterior chamber inflammation, and reduction of IOP.
CONCLUSION AND IMPORTANCE
In neonates and infants presenting with bilateral uveitis, spontaneous hyphema, and secondary glaucoma, even in the absence of a well-defined iris lesion, diffuse juvenile xanthogranuloma should be considered as a differential diagnosis.
PubMed: 37323587
DOI: 10.1016/j.ajoc.2023.101867 -
Brain Pathology (Zurich, Switzerland) Nov 2023
Topics: Child, Preschool; Humans; Male; Spinal Cord Neoplasms
PubMed: 37285582
DOI: 10.1111/bpa.13174 -
Archivos Argentinos de Pediatria Oct 2023The infiltration of leukemia cells into the skin, known as leukemia cutis, is a rare presentation of this disease and accounts for a diagnostic challenge. The main...
The infiltration of leukemia cells into the skin, known as leukemia cutis, is a rare presentation of this disease and accounts for a diagnostic challenge. The main differential diagnoses include infections, other neoplastic diseases with skin involvement and histiocytic disorders, among others, as they entail different prognostic and therapeutic approaches. Here we describe two patients who were initially diagnosed with leukemia cutis, whose final diagnosis was of non-malignant diseases.
Topics: Humans; Leukemia; Skin Neoplasms; Skin; Diagnosis, Differential
PubMed: 36857109
DOI: 10.5546/aap.2022-02796.eng