-
Cureus Oct 2023This editorial explores the potential link between vinyl chloride (VC) and cardiovascular diseases, specifically in the context of a recent train derailment in East...
This editorial explores the potential link between vinyl chloride (VC) and cardiovascular diseases, specifically in the context of a recent train derailment in East Palestine, Ohio. The primary finding of this article suggests a likely increased risk of cardiovascular factors associated with vinyl chloride exposure. This underscores the importance of proactive risk management and enhanced population monitoring. Together, these findings highlight the need for timely interventions to address cardiovascular health concerns in exposed populations.
PubMed: 37954788
DOI: 10.7759/cureus.46835 -
Heliyon Nov 2023The optical charge-transfer (CT) property and the crystal structure of (Z)-4-(1-cyano-2-(2,4,5-trimethoxyphenyl)vinyl)pyridin-1-ium chloride monohydrate salt (), which...
Color properties and non-covalent interactions in hydrated (Z)-4-(1-cyano-2-(2,4,5-trimethoxyphenyl)-vinyl)pyridin-1-ium chloride salt: Insights from experimental and theoretical studies.
The optical charge-transfer (CT) property and the crystal structure of (Z)-4-(1-cyano-2-(2,4,5-trimethoxyphenyl)vinyl)pyridin-1-ium chloride monohydrate salt (), which belongs to an acrylonitrile family, was studied. The title salt, , was characterized using different spectroscopy techniques and a single-crystal X-ray diffraction study combined with quantum chemical computations. The results showed that the color properties of are determined by the CT, changes in bandgap, optical absorption, and various non-covalent interactions. The HOMO-LUMO energy gaps are 5.41 eV and 5.23 eV for the precursor and salt, respectively. It was demonstrated that π-π stacking interactions lead to the formation of intercalated dimers and donor-acceptor interactions assisted by hydrogen bonds; the dimers and interactions are different between the precursor and the salt. The cation moiety is mainly stabilized by N(1)-H···Cl, and the anion is predominantly stabilized by strong O(1W)- H⋯ Cl bonds as well as the hydrogen bonds with the MeO group O(2W)-H⋯O(1) and O(2W)-H⋯O(1W). The charge transfer between cation and anion moieties in the structure is established through NBO analysis.
PubMed: 37954267
DOI: 10.1016/j.heliyon.2023.e21040 -
Heliyon Sep 2023Fish feed is becoming an increasingly vital source of nourishment for farmed fish, which are mainly coming from marine fish and agricultural sources. Anthropogenic...
Fish feed is becoming an increasingly vital source of nourishment for farmed fish, which are mainly coming from marine fish and agricultural sources. Anthropogenic particles, such as microplastics, are abundant in both marine fish and agricultural byproducts that are utilized to make fish feed. This study investigated whether fish feed could be a source of microplastic contamination, and revealed that a 20 weeks adult farmed tilapia fish might consume up to 268.45 ± 1.438 microplastic particles via fish feed where finisher type feeds were found to be mostly contributory in this number. The microplastics were initially observed with a stereomicroscope and FESEM-EDS. Polymeric composition of microplastics was determined to be polypropylene (PP), nylon-6 (NY-6), polyethylene terephthalate (PET), polystyrene (PS), polyvinyl alcohol (PVA), polyethylene (PE), high- and low-density polyethylene (HDPE, LDPE), ethylene vinyl acetate (EVA), polycarbonate (PC), poly vinyl acetate (PVAc), poly urethane (PU) and polyvinyl chloride (PVC) by FTIR. Results also revealed that the size of microplastic particles in all fish feed ranged from 14 μm to 4480 μm, with 550 ± 45.45 to 11,600 ± 56.1 microplastic particles/kg of fish feed. The FESEM-EDS data demonstrated to overlook the microplastic surface along with attachment of heavy metals onto that surface such as Pb, Ni, and Co in finisher type feed that could create additional health risks.
PubMed: 37809616
DOI: 10.1016/j.heliyon.2023.e19789 -
RSC Advances Sep 2023The design of new gas sensors and scavengers of volatile organic compounds (VOCs) is desirable for VOC enriching, separation and utilization. Herein, first-principles...
The design of new gas sensors and scavengers of volatile organic compounds (VOCs) is desirable for VOC enriching, separation and utilization. Herein, first-principles methods were performed to investigate the potential of CN monolayers as highly efficient sensors and scavengers for selective VOCs (toluene, benzene, vinyl chloride, ethane, methanal, acetone, ethanol, and acetaldehyde). The physisorption of toluene, benzene, acetone, ethanol, acetaldehyde, and methanal has relatively high adsorption strength and can significantly tune the electronic properties and work function () of the CN, indicating that the CN monolayer is highly sensitive and selective to these VOC gases. In addition, the desorption time of benzene, acetone, ethanol, acetaldehyde, and methanal is about 3, 0.4, 2.0 × 10, 3.0 × 10, and 3.6 × 10 s at 300 K, respectively, indicating that the CN-based sensor has high reusability at room temperature. The recovery time of toluene was about 7.8 × 10 s at 300 K, showing disposable toluene gas sensing of the monolayer. Our work confirms that the CN monolayer as a resistance-type and -type gas sensor and scavenger is highly sensitive, selective and reusable for VOCs (benzene, acetone, ethanol, acetaldehyde, and methanol), but is a disposable toluene gas sensor and scavenger at room temperature.
PubMed: 37790102
DOI: 10.1039/d3ra05573f -
Membranes Sep 2023In this work, poly(vinyl chloride)-based polymeric ionic liquid inclusion membranes were used in the selective separation of Fe(III), Zn(II), Cd(II), and Cu(II) from...
In this work, poly(vinyl chloride)-based polymeric ionic liquid inclusion membranes were used in the selective separation of Fe(III), Zn(II), Cd(II), and Cu(II) from hydrochloride aqueous solutions. The ionic liquids under study were 1-octyl-3-methylimidazolium hexafluorophosphate, [omim][PF] and methyl trioctyl ammonium chloride, [MTOA][Cl]. For this purpose, stability studies of different IL/base polymer compositions against aqueous phases were carried out. Among all polymer inclusion membranes studied, [omim][PF]/PVC membranes at a ratio of 30/70 and [MTOA][Cl]/PVC membranes at a ratio of 70/30 were able to retain up to 82% and 48% of the weight of the initial ionic liquid, respectively, after being exposed to a solution of metal ions in 1 M HCl for 2048 h (85 days). It was found that polymer inclusion membranes based on the ionic liquid methyl trioctyl ammonium chloride allowed the selective separation of Zn(II)/Cu(II) and Zn(II)/Fe(III) mixtures with separation factors of 1996, 606 and, to a lesser extent but also satisfactorily, Cd(II)/Cu(II) mixtures, with a separation factor of 112. Therefore, selecting the appropriate ionic liquid/base polymer mixture makes it possible to create polymeric inclusion membranes capable of selectively separating target metal ions.
PubMed: 37755217
DOI: 10.3390/membranes13090795 -
International Journal of Pharmaceutics Nov 2023Poly(vinyl chloride) (PVC) is widely used in the manufacture of medical devices. The plasticizers added to PVC are potentially toxic for humans, likely to migrate, and...
Poly(vinyl chloride) (PVC) is widely used in the manufacture of medical devices. The plasticizers added to PVC are potentially toxic for humans, likely to migrate, and thus unintentionally administered to patients. The objective of the present study was to reduce the migration of plasticizer (1,2-cyclohexanedicarboxylic acid, diisononylester (DINCH) or trioctyltrimellitate (TOTM)) from PVC by implementing a three-step surface treatment process: (i) pretreatment with low-pressure argon cold plasma, (ii) polydopamine coating, and (iii) post-treatment with cold plasma exposure or thermal treatment at 140 °C. Samples were then characterized in terms of the water contact angle (WCA) and the aspect in scanning electron microscopy. Plasticizer migration (n = 5) was measured using an HPLC technique with ultraviolet detection and found to depend on the treatment and the plasticizer. Plasticized PVC was hydrophobic, with a measured mean ± standard deviation WCA of 96.7 ± 3.6° for PVC-DINCH and 110.2 ± 5.8° for PVC-TOTM. Plasma post-treatment and thermal post-treatment were respectively associated with a mean decrease in migration of 38.3 ± 1.9% for DINCH and 61.5 ± 4.4% for TOTM. Our results are promising with regard to limiting the migration of plasticizers into the patient's blood and thus enabling the development of safer medical devices.
PubMed: 37722492
DOI: 10.1016/j.ijpharm.2023.123422 -
Nature Communications Sep 2023Carbon supports are ubiquitous components of heterogeneous catalysts for acetylene hydrochlorination to vinyl chloride, from commercial mercury-based systems to more...
Carbon supports are ubiquitous components of heterogeneous catalysts for acetylene hydrochlorination to vinyl chloride, from commercial mercury-based systems to more sustainable metal single-atom alternatives. Their potential co-catalytic role has long been postulated but never unequivocally demonstrated. Herein, we evidence the bifunctionality of carbons and metal sites in the acetylene hydrochlorination catalytic cycle. Combining operando X-ray absorption spectroscopy with other spectroscopic and kinetic analyses, we monitor the structure of single metal atoms (Pt, Au, Ru) and carbon supports (activated, non-activated, and nitrogen-doped) from catalyst synthesis, using various procedures, to operation at different conditions. Metal atoms exclusively activate hydrogen chloride, while metal-neighboring sites in the support bind acetylene. Resolving the coordination environment of working metal atoms guides theoretical simulations in proposing potential binding sites for acetylene in the support and a viable reaction profile. Expanding from single-atom to ensemble catalysis, these results reinforce the importance of optimizing both metal and support components to leverage the distinct functions of each for advancing catalyst design.
PubMed: 37689779
DOI: 10.1038/s41467-023-41344-0 -
ACS Sustainable Chemistry & Engineering Sep 2023The synthesis of the vinyl chloride monomer (VCM), employed to manufacture poly(vinyl chloride) (PVC) plastic, primarily relies on oil-derived ethylene, resulting in...
The synthesis of the vinyl chloride monomer (VCM), employed to manufacture poly(vinyl chloride) (PVC) plastic, primarily relies on oil-derived ethylene, resulting in high costs and carbon footprint. Natural gas-derived ethane in VCM synthesis has long been considered a transformative feedstock to lower emissions and expenses. In this work, we evaluate the environmental potential and economics of recently developed catalytic ethane chlorination technologies for VCM synthesis. We consider the ethylene-based business-as-usual (BAU) route and two different ethane-based processes evaluated at their current development level and their full potential, , ideal conversion and selectivity. All routes are assessed under two temporal scenarios: present (2020) and prospective (2050). Combining process simulation and life cycle assessment (LCA), we find that catalytic ethane chlorination technologies can lower the production cost by 32% at their current development state and by 56% when considering their full potential. Though environmentally disadvantageous in the 2020 scenario, they emerge as more sustainable alternatives to the BAU in the 2050 scenario, reducing the carbon footprint of VCM synthesis by up to 26% at their current state and up to 58% at their full potential. Going beyond VCM synthesis, our results highlight prospective LCA as a powerful tool for assessing the true environmental implications of emerging technologies under more decarbonized future energy scenarios.
PubMed: 37680580
DOI: 10.1021/acssuschemeng.3c03006 -
JMIR Dermatology Sep 2023Environmental vinyl chloride (VC) exposure may result in serious acute and chronic dermatological conditions. Because existing literature largely focuses on exposures in... (Review)
Review
BACKGROUND
Environmental vinyl chloride (VC) exposure may result in serious acute and chronic dermatological conditions. Because existing literature largely focuses on exposures in occupational settings, a gap persists in our understanding of the medical consequences of large-scale chemical spills.
OBJECTIVE
This study aims to examine the potential dermatological manifestations of VC exposure in the context of industrial spills and other environmental disasters and to highlight the public health and justice implications of such releases.
METHODS
In this narrative review, relevant evidence-based, peer-reviewed scientific sources, gray literature, and media reports were identified via searches of search PubMed and Google using predetermined keyword search terms related to VC, VC spills and releases, train derailment, cutaneous disease, public health, and vulnerable and marginalized populations.
RESULTS
Contact dermatitis and frostbite may arise acutely, highlighting the importance of swift decontamination. Long-term manifestations from chronic VC exposure due to persistence in environmental reservoirs include Raynaud disease, sclerodermatous skin changes, acro-osteolysis, and cutaneous malignancies. The clinical severity of cutaneous manifestations is influenced by individual susceptibility as well as duration, intensity, and route of exposure. Additionally, chemical releases of VC more frequently impact Communities of Color and those of lower socioeconomic status, resulting in greater rates of exposure-related disease.
CONCLUSIONS
With environmental release events of hazardous chemicals becoming increasingly common and because the skin has increased contact with environmental toxins relative to other organs, an urgent need exists for a greater understanding of the overall short- and long-term health impacts of large-scale, toxic exposures, underscoring the need for ongoing clinical vigilance. Dermatologists and public health officials should also aim to better understand the ways in which the disproportionate impacts of hazardous chemical exposures on lower-income and minority populations may exacerbate existing health disparities. Herein, we describe the health implications of toxic releases with particular consideration paid to marginalized and vulnerable populations. In addition to legal and regulatory frameworks, we advocate for improved public health measures, to not only mitigate the risk of environmental catastrophes in the future, but also ensure timely and effective responses to them.
PubMed: 37676716
DOI: 10.2196/48998 -
Water Research Oct 2023Vinyl chloride (VC) is a dominant carcinogenic residual in many aged chlorinated solvent plumes, and it remains a huge challenge to clean it up. Zerovalent iron (ZVI) is...
Vinyl chloride (VC) is a dominant carcinogenic residual in many aged chlorinated solvent plumes, and it remains a huge challenge to clean it up. Zerovalent iron (ZVI) is an effective reductant for many chlorinated compounds but shows low VC removal efficiency at field scale. Amendment of ZVI with a carbonaceous material may be used to both preconcentrate VC and facilitate redox reactions. In this study, nitrogen-doped graphene (NG) produced by a simple co-pyrolysis method using urea as nitrogen (N) source, was tested as a catalyst for VC reduction by nanoscale ZVI (nZVI). The extent of VC reduction to ethylene in the presence of 2 g/L of nZVI was less than 1% after 3 days, and barely improved with the addition of 4 g/L of graphene. In contrast, with amendment of nZVI with NG produced at pyrolysis temperature (PT) of 950 °C, the VC reduction extent increased more than 10-fold to 69%. The reactivity increased with NG PT increasing from 400 °C to an optimum at 950 °C, and it increased linearly with NG loadings. Interestingly, N dosage had little effect on reactivity if NG was produced at PT of 950 °C, while a positive correlation was observed for NG produced at PT of 600 °C. XPS and Raman analyses revealed that for NG produced at lower PT (<800 °C) mainly the content of pyridine-N-oxide (PNO) groups correlates with reactivity, while for NG produced at higher PT up to 950 °C, reactivity correlates mainly with N induced structural defects in graphene. The results of quenching and hydrogen yield experiments indicated that NG promote reduction of VC by storage of atomic hydrogen, thus increasing its availability for VC reduction, while likely also enabling electron transfer from nZVI to VC. Overall, these findings demonstrate effective chemical reduction of VC by a nZVI-NG composite, and they give insights into the effects of N doping on redox reactivity and hydrogen storage potential of carbonaceous materials.
Topics: Vinyl Chloride; Graphite; Catalysis; Hydrogen; Iron; Nitrogen
PubMed: 37660466
DOI: 10.1016/j.watres.2023.120535