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JAMA Dermatology May 2020
Topics: Child, Preschool; Diagnosis, Differential; Female; Humans; Lower Extremity; Pagetoid Reticulosis; Skin
PubMed: 32129789
DOI: 10.1001/jamadermatol.2020.0059 -
The American Journal of Dermatopathology Sep 2020Pseudocarcinomatous hyperplasia (PCH) is a benign reactive epithelial proliferation that may be associated to lymphomas of the skin or external mucous membranes. We... (Review)
Review
Pseudocarcinomatous Hyperplasia, Squamous Cell Carcinoma, and Keratoacanthoma Associated to Lymphomas of the Skin and External Mucous Membranes: A Case Report and Literature Review.
Pseudocarcinomatous hyperplasia (PCH) is a benign reactive epithelial proliferation that may be associated to lymphomas of the skin or external mucous membranes. We present a case of single lesion mycosis fungoides (Woringer-Kollop's reticulosis pagetoid) associated with PCH that was initially misdiagnosed as squamous cell carcinoma (SCC) and review all PubMed-indexed previously reported cases on lymphomas of the skin or external mucous membranes associated to PCH, SCC, and keratoacanthomas. Including our own case, we collected data of 114 cases of cutaneous or mucosal lymphoproliferative disorders associated to PCH, 3 cases associated to SCC, and other 3 cases associated to keratoacanthomas. All cases were tabulated to the following parameters whenever data was available: sex, age, previous medical conditions, number of lesions (single × multiple), site of involvement (mucosa, skin or both), clinical impression, initial equivocal histopathologic diagnosis, final diagnosis, keratinocytic atypia (presence × absence), lymphocytic atypia (presence × absence), CD30-status, and treatment.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Biopsy; Carcinoma, Squamous Cell; Child; Diagnostic Errors; Female; Humans; Hyperplasia; Immunohistochemistry; Keratoacanthoma; Male; Middle Aged; Mucous Membrane; Pagetoid Reticulosis; Predictive Value of Tests; Skin; Skin Neoplasms; Young Adult
PubMed: 31833842
DOI: 10.1097/DAD.0000000000001587 -
Journal of Cutaneous Pathology May 2020Pagetoid reticulosis (PR) is a rare lymphoproliferative disorder with indolent behavior considered a variant of mycosis fungoides. It is characterized by marked... (Review)
Review
Pagetoid reticulosis (PR) is a rare lymphoproliferative disorder with indolent behavior considered a variant of mycosis fungoides. It is characterized by marked epidermotropism of the neoplastic lymphocytes. Since its original description, five cases have been reported in children. We report a new case of PR with an immunohistochemical profile not previously described in children.
Topics: Administration, Topical; Adolescent; Biopsy; Child; Child, Preschool; Clobetasol; Female; Glucocorticoids; Humans; Immunohistochemistry; Immunophenotyping; Lymphocytes; Lymphoproliferative Disorders; Male; Mycosis Fungoides; Pagetoid Reticulosis; Skin; Skin Neoplasms; Treatment Outcome
PubMed: 31785005
DOI: 10.1111/cup.13622 -
Photodermatology, Photoimmunology &... Sep 2019Pagetoid reticulosis (PR), also known as Woringer-Kolopp disease, is a rare variant of mycosis fungoides with distinctive clinicopathologic features. It clinically...
Pagetoid reticulosis (PR), also known as Woringer-Kolopp disease, is a rare variant of mycosis fungoides with distinctive clinicopathologic features. It clinically manifests as a solitary, erythematous, gradually enlarging, scaly, or verrucous plaque on the lower extremities, and due to its indolent course and nonspecific clinical features, may remain undiagnosed for years. In the current study, we describe the clinical and dermoscopic characteristics of a rare case of PR disease and correlate them with the corresponding histopathologic findings. Dermoscopy may prove beneficial in early diagnosis of this rare entity.
Topics: Aged; Dermoscopy; Humans; Male; Pagetoid Reticulosis; Skin; Skin Neoplasms
PubMed: 31006145
DOI: 10.1111/phpp.12472