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Journal of Functional Biomaterials Apr 2023Zinc-based biodegradable metals (BMs) have been developed for biomedical implant materials. However, the cytotoxicity of Zn and its alloys has caused controversy. This... (Review)
Review
Zinc-based biodegradable metals (BMs) have been developed for biomedical implant materials. However, the cytotoxicity of Zn and its alloys has caused controversy. This work aims to investigate whether Zn and its alloys possess cytotoxic effects and the corresponding influence factors. According to the guidelines of the PRISMA statement, an electronic combined hand search was conducted to retrieve articles published in PubMed, Web of Science, and Scopus (2013.1-2023.2) following the PICOS strategy. Eighty-six eligible articles were included. The quality of the included toxicity studies was assessed utilizing the ToxRTool. Among the included articles, extract tests were performed in 83 studies, and direct contact tests were conducted in 18 studies. According to the results of this review, the cytotoxicity of Zn-based BMs is mainly determined by three factors, namely, Zn-based materials, tested cells, and test system. Notably, Zn and its alloys did not exhibit cytotoxic effects under certain test conditions, but significant heterogeneity existed in the implementation of the cytotoxicity evaluation. Furthermore, there is currently a relatively lower quality of current cytotoxicity evaluation in Zn-based BMs owing to the adoption of nonuniform standards. Establishing a standardized in vitro toxicity assessment system for Zn-based BMs is required for future investigations.
PubMed: 37103296
DOI: 10.3390/jfb14040206 -
The International Journal of Oral &... 2023To evaluate the marginal accuracy of soft-milled cobalt-chromium (Co-Cr) compared to other construction methods/restorative materials in tooth/implant-supported... (Meta-Analysis)
Meta-Analysis
To evaluate the marginal accuracy of soft-milled cobalt-chromium (Co-Cr) compared to other construction methods/restorative materials in tooth/implant-supported restorations. PICO questions were defined, and a systematic search was conducted in six electronic databases. Titles and abstracts were collected and screened by two independent reviewers. After removing duplicate articles, the full texts of relevant articles were gathered, and the required information and data were extracted. Risk of bias was assessed and meta-analyses of the collected data were conducted using STATA software version 16. A total of 1,914 experimental and clinical articles were reviewed, and 18 studies were selected for qualitative analysis. The 16 studies that were included in the meta-analysis showed no significant marginal gap differences between soft-milled Co-Cr and the following methods/materials: hard-milled Co-Cr (I = 92.9%, = .86), casting wax (I = 90.9%, = .42), laser-sintered Co-Cr (I = 93.3%, = .46), and zirconia (I = 0.00%, = .47). However, a significantly higher marginal accuracy of soft-milled Co-Cr was observed when compared to milled-wax casting (I = 93.1%, < .001). The marginal gap of soft-milled Co-Cr restorations is within the acceptable clinical range and provides an accuracy similar to other available methods/materials for both the prepared implant abutment and tooth.
Topics: Chromium Alloys; Dental Materials; Computer-Aided Design; Dental Marginal Adaptation; Dental Prosthesis Design
PubMed: 37099579
DOI: 10.11607/jomi.9782 -
EFORT Open Reviews Apr 2023The biomechanical characteristics of different techniques to perform the modified Lapidus procedure are controversial, discussing the issue of stability, rigidity, and... (Review)
Review
PURPOSE
The biomechanical characteristics of different techniques to perform the modified Lapidus procedure are controversial, discussing the issue of stability, rigidity, and compression forces from a biomechanical point of view. The aim of this systematic review was to investigate the available options to identify whether there is a procedure providing superior biomechanical results.
METHODS
A comprehensive literature search was performed by screening PubMed, Embase, and Cochrane databases until September 2021. There was a wide heterogeneity of the available data in the different studies. Load to failure, stiffness, and compression forces were summarized and evaluated.
RESULTS
Seventeen biomechanical studies were retrieved - ten cadaveric and seven polyurethane foam (artificial bone) studies. Fixation methods ranged from the classic crossed screw approach (n = 5) to plates (dorsomedial and plantar) with or without compression screws (n = 11). Newer implants such as intramedullary stabilization screws (n = 1) and memory alloy staples (n = 2) were investigated.
CONCLUSION
The two crossed screws construct is still a biomechanical option; however, according to this systematic review, there is strong evidence that a plate-screw construct provides superior stability especially in combination with a compression screw. There is also evidence about plate position and low evidence about compression screw position. Plantar plates seem to be advantageous from a biomechanical point of view, whereas compression screws could be better when positioned outside the plate. Overall, this review suggests the biomechanical advantages of using a combination of locking plates with a compression screw.
PubMed: 37097047
DOI: 10.1530/EOR-22-0069 -
Clinical Spine Surgery Feb 2024Systematic review.
STUDY DESIGN
Systematic review.
OBJECTIVE
To examine the outcomes of customized 3-dimensional (3D) printed implants for spinal reconstruction after tumor resection.
SUMMARY OF BACKGROUND DATA
Various techniques exist for spinal reconstruction after tumor resection. Currently, there is no consensus regarding the utility of customized 3D-printed implants for spinal reconstruction after tumor resection.
MATERIALS AND METHODS
A systematic review was registered with PROSPERO and performed according to "Preferred Reporting Items for Systematic Reviews and Meta-analyses" guidelines. All level I-V evidence studies reporting the use of 3D-printed implants for spinal reconstruction after tumor resection were included.
RESULTS
Eleven studies (65 patients; mean age, 40.9 ± 18.1 y) were included. Eleven patients (16.9%) underwent intralesional resections with positive margins and 54 patients (83.1%) underwent en bloc spondylectomy with negative margins. All patients underwent vertebral reconstruction with 3D-printed titanium implants. Tumor involvement was in the cervical spine in 21 patients (32.3%), thoracic spine in 29 patients (44.6%), thoracolumbar junction in 2 patients (3.1%), and lumbar spine in 13 patients (20.0%). Ten studies with 62 patients reported perioperative outcomes radiologic/oncologic status at final follow-up. At the mean final follow-up of 18.5 ± 9.8 months, 47 patients (75.8%) had no evidence of disease, 9 patients (14.5%) were alive with recurrence, and 6 patients (9.7%) had died of disease. One patient who underwent C3-C5 en bloc spondylectomy had an asymptomatic subsidence of 2.7 mm at the final follow-up. Twenty patients that underwent thoracic and/or lumbar reconstruction had a mean subsidence of 3.8 ± 4.7 mm at the final follow-up; however, only 1 patient had a symptomatic subsidence that required revision surgery. Eleven patients (17.7%) had one or more major complications.
CONCLUSION
There is some evidence to suggest that using customized 3D-printed titanium or titanium alloy implants is an effective technique for spinal reconstruction after tumor resection. There is a high incidence of asymptomatic subsidence and major complications that are similar to other methods of reconstruction.
LEVEL OF EVIDENCE
Level V, systematic review of level I-V studies.
Topics: Humans; Young Adult; Adult; Middle Aged; Titanium; Spinal Neoplasms; Lumbar Vertebrae; Cervical Vertebrae; Prostheses and Implants
PubMed: 37074792
DOI: 10.1097/BSD.0000000000001462 -
Neuroscience and Biobehavioral Reviews Jul 2023Elevated inflammation is a risk factor for many psychiatric (e.g., depression) and somatic conditions (e.g., rheumatoid arthritis). Inflammation is influenced by... (Review)
Review
Elevated inflammation is a risk factor for many psychiatric (e.g., depression) and somatic conditions (e.g., rheumatoid arthritis). Inflammation is influenced by psychosocial processes such as emotion regulation. Characterization of which emotion regulation characteristics impact inflammation could help refine psychosocial interventions aimed at normalizing health-harming inflammatory activity for individuals with psychiatric and somatic illnesses. To investigate this issue, we systematically reviewed the literature on associations between a variety of emotion regulation traits and inflammation. Out of 2816 articles identified, 38 were included in the final review. 28 (74%) found that (a) poor emotion regulation is associated with higher inflammation and/or (b) strong emotion regulation skills are associated with lower inflammation. Consistency of results differed as a function of the emotion regulation construct investigated and methodological characteristics. Results were most consistent for studies testing positive coping/social support seeking or broadly defined emotion regulation/dysregulation. Methodologically, studies testing reactivity to a stressor, adopting a vulnerability-stress framework, or using longitudinal data were most consistent. Implications for integrated, transdiagnostic psychoimmunological theories are discussed, as well as recommendations for clinical research.
Topics: Humans; Emotions; Emotional Regulation; Inflammation; Risk Factors; Phenotype
PubMed: 37028579
DOI: 10.1016/j.neubiorev.2023.105162 -
Biomedical Materials (Bristol, England) Apr 2023Guided bone/tissue regeneration (GBR/GTR) is commonly used in dental treatment. The desired bone/tissue regeneration is achieved by placing a barrier membrane over the... (Meta-Analysis)
Meta-Analysis
Guided bone/tissue regeneration (GBR/GTR) is commonly used in dental treatment. The desired bone/tissue regeneration is achieved by placing a barrier membrane over the defect to avoid the downward growth of faster-growing connective and epithelial tissue into the defect. This review aimed to evaluate osteogenic properties, degradation characteristics, and postoperative complications of eight biodegradable membranes in animal experiments, including non-crosslinked collagen membrane (NCCM), crosslinked collagen membrane (CCM), silk membrane (SM), polylactic-co-glycolic acid, polylactic acid, polyethylene glycol hydrogel, polycaprolactone (PCL), and magnesium alloys. Seven electronic databases (PubMed, Embase, Web of Science, Cochrane Library, Science Direct, Wiley, Scopus and Google Scholar) were screened. Study selection, data extraction and quality assessment were made in duplicate. The SYRCLE assessment tool, CERQual (Confidence in the Evidence from Reviews of Qualitative Research) tool and GRADE tool were used to grade the risk of bias and level of evidence. A total of 2512 articles were found in the electronic database. Finally, 94 articles were selected, of which 53 were meta-analyzed. Surface under the cumulative ranking curve showed the best results for new bone formation in the magnesium barrier membrane group, followed by SM, PCL, NCCM, and CCM. Qualitative analysis showed good biocompatibility for natural polymer membranes and a longer degradation time for synthetic polymer membranes. In addition, 34 studies all showed high bias risks, while other studies had unclear bias risks. Natural polymer membranes were more effective for bone regeneration and magnesium alloys were proved to be promising barrier materials that warrant future research.
Topics: Animals; Bone Regeneration; Collagen; Guided Tissue Regeneration; Magnesium; Membranes, Artificial; Network Meta-Analysis; Polymers
PubMed: 37001532
DOI: 10.1088/1748-605X/acc99a -
The Saudi Dental Journal Feb 2023The aim of this systematic review was to present the current knowledge on the influence of laser surface treatment on the adhesion of bacteria to titanium and its alloys. (Review)
Review
OBJECTIVE
The aim of this systematic review was to present the current knowledge on the influence of laser surface treatment on the adhesion of bacteria to titanium and its alloys.
DESIGN
This review was structured according to PRISMA guidelines for systematic reviews and -analyses, and registered on the Open Science Framework platform (https://doi.org/10.17605/OSF.IO/FTA3W). Article searches were performed in 4 databases: PubMed, Scopus, Embase, and Science Direct. In addition, a manual search was performed in the reference lists of the selected articles. The selection of articles was performed by two reviewers. The articles found were screened for eligibility using the previously established inclusion and exclusion criteria. The methodological quality of the studies was assessed using the Joanna Briggs Institute (JBI) Critical Assessment Checklist for Quasi-Experimental Studies (non-randomized experimental studies).
RESULTS
Most of the studies evaluated showed that surface treatment by laser irradiation can affect the adhesion of bacteria to titanium surfaces and that this is directly related to changes in surface properties such as chemical composition, morphology, roughness, and wettability, as well as the type of bacterial species involved.
CONCLUSIONS
The studies considered in this systematic review have shown that surface treatment by laser irradiation is a promising technique to reduce the adhesion of bacteria on the surface of titanium implants.
PubMed: 36942202
DOI: 10.1016/j.sdentj.2023.01.004 -
The Journal of Evidence-based Dental... Mar 2023Liu S, Silikas N, Ei-Angbawi A. Analysis of the effectiveness of the fiber-reinforced composite lingual retainer: A systematic review and meta-analysis. Am J Orthod... (Meta-Analysis)
Meta-Analysis
FIBER REINFORCED COMPOSITE RETAINERS MAY BE AS EFFECTIVE AS MULTISTRANDED STAINLESS-STEEL WIRES IN FAILURE RATES AND MINIMAL ADVERSE EFFECT, BUT SUPERIOR IN TERMS OF RELAPSE AND PATIENT SATISFACTION.
ARTICLE TITLE AND BIBLIOGRAPHIC INFORMATION
Liu S, Silikas N, Ei-Angbawi A. Analysis of the effectiveness of the fiber-reinforced composite lingual retainer: A systematic review and meta-analysis. Am J Orthod Dentofacial Orthop. 2022 Aug 26:S0889-5406(22)00,432-2. doi: 10.1016/j.ajodo.2022.07.003. Epub ahead of print. PMID: 36,031,511.
SOURCE OF FUNDING
Not reported.
TYPE OF STUDY/DESIGN
Systematic review with meta-analysis of data.
Topics: Humans; Dental Bonding; Patient Satisfaction; Stainless Steel; Orthodontic Retainers; Orthodontic Wires; Orthodontic Appliance Design; Recurrence
PubMed: 36914296
DOI: 10.1016/j.jebdp.2023.101843 -
The Journal of Evidence-based Dental... Mar 2023Delucchi, F.; De Giovanni, E.; Pesce, P.; Bagnasco, F.; Pera, F.; Baldi, D.; Menini, M. Framework Materials for Full-Arch Implant-Supported Rehabilitations: A Systematic...
ARTICLE TITLE AND BIBLIOGRAPHIC INFORMATION
Delucchi, F.; De Giovanni, E.; Pesce, P.; Bagnasco, F.; Pera, F.; Baldi, D.; Menini, M. Framework Materials for Full-Arch Implant-Supported Rehabilitations: A Systematic Review of Clinical Studies. Materials 2021, 14, 3251. https:// doi.org/10.3390/ma14123251 SOURCE OF FUNDING: This research received no funding.
TYPE OF STUDY/DESIGN
Systematic Review (SR).
Topics: Humans; Dental Implants; Dental Prosthesis, Implant-Supported; Zirconium
PubMed: 36914295
DOI: 10.1016/j.jebdp.2022.101799 -
Materials Today. Bio Apr 2023The biological functions of rare-earth elements (REEs) have become a focus of intense research. Recent studies have demonstrated that ion doping or alloying of some REEs... (Review)
Review
The biological functions of rare-earth elements (REEs) have become a focus of intense research. Recent studies have demonstrated that ion doping or alloying of some REEs can optimize the properties of traditional biomaterials. Europium (Eu), which is an REE with low toxicity and good biocompatibility, has promising applications in biomedicine. This article systematically reviews the osteogenic, angiogenic, neuritogenic, antibacterial, and anti-tumor properties of Eu-containing biomaterials, thereby paving the way for biomedical applications of Eu. Data collection for this review was completed in October 2022, and 30 relevant articles were finally included. Most articles indicated that doping of Eu ions or Eu-compound nanoparticles in biomaterials can improve their osteogenic, angiogenic, neuritogenic, antibacterial, and anti-tumor properties. The angiogenic, antibacterial, and potential neuritogenic effects of Eu(OH) nanoparticles have also been demonstrated.
PubMed: 36910271
DOI: 10.1016/j.mtbio.2023.100595