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Revista de Neurologia May 2010Fatigue is the most common symptom and the most disabling in patients with post-polio syndrome. (Review)
Review
INTRODUCTION
Fatigue is the most common symptom and the most disabling in patients with post-polio syndrome.
AIM
To analyze the effectiveness of various treatments used to improve fatigue syndrome patients post-polio.
MATERIALS AND METHODS
Systematic review. Is defined a bibliographic search strategy in Medline (from 1961), EMBASE (from 1980), ISI Web of Knowledge and Cochrane Library, Cochrane Central Register of Controlled Trials (CENTRAL), AMED (January 1985), EMI and Physiotherapy Evidence Database (PEDro) until February 2008, the population defined (post-polio syndrome patients) and intervention (any treatment for fatigue in these patients). Outcome were selected as different scales of fatigue and fatigue or vitality dimension scales quality of life. Clinical trials were selected.
RESULTS
We retrieved 396 articles, of which 23 were analyzed in detail. Finally, 19 were included in the analysis, a total of 705 patients.
CONCLUSIONS
Lamotrigine, bromocriptine, aerobics and flexibility exercises, hydrokinesitherapy and technical aids are treatment techniques that reduce more fatigue in these patients.
Topics: Clinical Trials as Topic; Databases, Factual; Exercise Therapy; Fatigue; Humans; Postpoliomyelitis Syndrome; Quality of Life; Treatment Outcome
PubMed: 20473835
DOI: No ID Found -
The Journal of Bone and Joint Surgery.... Oct 2009Neurological conditions affecting the hip pose a considerable challenge in replacement surgery since poor and imbalanced muscle tone predisposes to dislocation and... (Review)
Review
Neurological conditions affecting the hip pose a considerable challenge in replacement surgery since poor and imbalanced muscle tone predisposes to dislocation and loosening. Consequently, total hip replacement (THR) is rarely performed in such patients. In a systematic review of the literature concerning THR in neurological conditions, we found only 13 studies which described the outcome. We have reviewed the evidence and discussed the technical challenges of this procedure in patients with cerebral palsy, Parkinson's disease, poliomyelitis and following a cerebrovascular accident, spinal injury or development of a Charcot joint. Contrary to traditional perceptions, THR can give a good outcome in these often severely disabled patients.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Arthropathy, Neurogenic; Arthroplasty, Replacement, Hip; Central Nervous System Diseases; Cerebral Palsy; Female; Hip Joint; Humans; Male; Middle Aged; Parkinson Disease; Poliomyelitis; Prognosis; Prosthesis Failure; Spinal Injuries; Stroke; Treatment Outcome; Young Adult
PubMed: 19794158
DOI: 10.1302/0301-620X.91B10.22934 -
Leukemia Oct 2006Intensified chemotherapy regimens resulting in improved survival of children with acute lymphocytic leukemia (ALL) lead to concerns about therapy-induced immune damage... (Review)
Review
Intensified chemotherapy regimens resulting in improved survival of children with acute lymphocytic leukemia (ALL) lead to concerns about therapy-induced immune damage reflected by the loss of protection of previous immunizations and the efficacy of (re-)vaccination. The severity of secondary immunodeficiency, however, is not clear and knowledge is based on a limited number of studies. We performed a systematic review on literature concerning vaccination data of children with ALL published since 1980. Eight studies fulfilled the inclusion criteria. Regarding antibody titers after treatment, the number of children who had preserved the defined protection level for antibodies differed widely, ranging from 17 to 98% for diphtheria, 27 to 82% for Bordetella pertussis, 20 to 98% for tetanus, 62 to 100% for poliomyelitis, 35 to 100% for Haemophilus influenzae type B (HiB), 29 to 92% for mumps, 29 to 60% for measles and 72 to 92% for rubella. Most patients however responded to revaccination, demonstrating immunological recovery. Although the designs and results of the included studies varied widely, it can be concluded that cytostatic therapy for ALL in children results in a temporarily reduction of specific antibody levels. Memory is preserved but revaccination may be warranted. This is the first systematic review and the best possible current approximation of chemotherapy-induced immune damage in children after ALL treatment.
Topics: Antibodies; Child; Humans; Precursor Cell Lymphoblastic Leukemia-Lymphoma; Vaccination; Vaccines
PubMed: 16888619
DOI: 10.1038/sj.leu.2404326 -
Archives of Physical Medicine and... Aug 2005To review systematically studies of late-onset polio sequelae on the course of functional status and muscle strength over time and to identify prognostic factors of... (Review)
Review
OBJECTIVES
To review systematically studies of late-onset polio sequelae on the course of functional status and muscle strength over time and to identify prognostic factors of change.
DATA SOURCES
We conducted a computerized literature search up to July 2004 in MEDLINE, EMBASE, CINAHL, Web of Science, PsychInfo, and the Cochrane controlled trial register using the key words: postpolio, postpoliomyelitis, postpoliomyelitis syndrome, post poliomyelitis muscular atrophy, and poliomyelitis.
STUDY SELECTION
Reports were selected by 1 reviewer if the study involved subjects with a history of poliomyelitis, the outcome measures described functional status or muscle strength, and follow-up was for at least 6 months.
DATA EXTRACTION
Studies were summarized with regard to population, design, sample size, outcome measures, results, and methodologic scores. Overlap in populations between studies was checked.
DATA SYNTHESIS
Of 71 potentially relevant studies, 19 were included (2 on functional status, 15 on muscle strength, 2 on both muscle strength and functional status). Two studies on the course of functional status had sufficient quality and reported inconsistent results. Four studies on the course of muscle strength had sufficient quality. Two studies reported a decline in strength and 2 reported no change. Decline in strength was only reported in studies with a follow-up period longer than 2 years. One study reported extent of paresis as a prognostic factor for change in perceived physical mobility.
CONCLUSIONS
Conclusions cannot be drawn from the literature with regard to the functional course or prognostic factors in late-onset polio sequelae. The rate of decline in muscle strength is slow, and prognostic factors have not yet been identified. Long-term follow-up studies with unselected study populations and age-matched controls are needed, with specific focus on prognostic factors.
Topics: Activities of Daily Living; Humans; Muscle, Skeletal; Postpoliomyelitis Syndrome
PubMed: 16084828
DOI: 10.1016/j.apmr.2004.12.022 -
Australian Family Physician Sep 1997Patients who in earlier life suffered from acute poliomyelitis are reporting new and disabling symptoms that have been variously labelled the 'late sequelae' or 'post... (Review)
Review
Patients who in earlier life suffered from acute poliomyelitis are reporting new and disabling symptoms that have been variously labelled the 'late sequelae' or 'post polio syndrome'. Systematic review of such patients has identified specific categories of disability. A practical investigation and management plan for such patients presenting to a general practitioner is proposed.
Topics: Australia; Female; Humans; Male; Physical Examination; Postpoliomyelitis Syndrome; Prognosis
PubMed: 9382720
DOI: No ID Found