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Klinische Padiatrie Nov 2016Chemotherapy-induced peripheral neuropathy is a frequent side-effect of drugs that are used in the treatment of cancer. Affected individuals can suffer from motor,... (Review)
Review
Chemotherapy-induced peripheral neuropathy is a frequent side-effect of drugs that are used in the treatment of cancer. Affected individuals can suffer from motor, sensory or autonomy nerve damage. Further medication is used for the treatment of CIPN which can cause further side-effects. Patients should be offered physical therapy treatment to relieve the symptoms. The aim of this article is to give an overview of available literature investigating physical therapy in CIPN in pediatric oncology. To determine relevant literature, a systematic review was conducted in the databases CINAHL, The Cochrane Library, ERIC, MEDPILOT, PEDro, PsycARTICLES, PsycINFO, PubMed and DIMDI. Besides the methodological quality of the identified literature is supposed to be reviewed. There is no current literature regarding the subject of this article, so no evaluation of the quality could be carried out. Although several publications concerning adults could be identified and transfer could be established for pediatrics. Acupuncture appeared to be effective in the treatment of CIPN in adults. Good results appeared especially regarding pain. Sensorimotor training, balance training, electrotherapy and alternative methods like Reiki and Yoga showed good results for patients symptoms. These treatment methods give a future prospect how CIPN in children can be treated successfully - but further pediatric research is necessary.
Topics: Acupuncture Therapy; Antineoplastic Agents; Child; Humans; Neoplasms; Peripheral Nervous System Diseases; Physical Therapy Modalities; Treatment Outcome
PubMed: 27846661
DOI: 10.1055/s-0042-111692 -
The Cochrane Database of Systematic... Sep 2016Therapeutic Touch (TT) is an alternative therapy that has gained popularity over the past two decades for helping wounds to heal. Practitioners enter a meditative state... (Review)
Review
BACKGROUND
Therapeutic Touch (TT) is an alternative therapy that has gained popularity over the past two decades for helping wounds to heal. Practitioners enter a meditative state and pass their hands above the patient's body to find and correct any imbalances in the patient's 'life energy' or chi. Scientific instruments have been unable to detect this energy. The effect of TT on wound healing has been expounded in anecdotal publications.
OBJECTIVES
To identify and review all relevant data to determine the effects of TT on healing acute wounds.
SEARCH METHODS
In January 2014, for this fifth update, we searched The Cochrane Wounds Group Specialised Register; The Cochrane Central Register of Controlled Trials (CENTRAL) (The Cochrane Library); Ovid MEDLINE; Ovid MEDLINE (In-Process & Other Non-Indexed Citations); Ovid EMBASE; and EBSCO CINAHL.
SELECTION CRITERIA
All randomised or quasi-randomised controlled trials, which compared the effect of TT with a placebo, another treatment, or no treatment control were considered. Studies which used TT as a stand-alone treatment, or as an adjunct to other therapies, were eligible.
DATA COLLECTION AND ANALYSIS
One author (DO'M) determined the eligibility for inclusion of all trials in the review. Both authors conducted data extraction and evaluation of trial validity independently. Each trial was assessed using predetermined criteria.
MAIN RESULTS
No new trials were identified for this update. Four trials in people with experimental wounds were included. The effect of TT on wound healing in these studies was variable. Two trials (n = 44 & 24) demonstrated a significant increase in healing associated with TT, while one trial found significantly worse healing after TT and the other found no significant difference. All trials are at high risk of bias.
AUTHORS' CONCLUSIONS
There is no robust evidence that TT promotes healing of acute wounds.
PubMed: 27581995
DOI: 10.1002/14651858.CD002766.pub6 -
The Cochrane Database of Systematic... Aug 2016Therapeutic Touch (TT) is an alternative therapy that has gained popularity over the past two decades for helping wounds to heal. Practitioners enter a meditative state... (Meta-Analysis)
Meta-Analysis Review
BACKGROUND
Therapeutic Touch (TT) is an alternative therapy that has gained popularity over the past two decades for helping wounds to heal. Practitioners enter a meditative state and pass their hands above the patient's body to find and correct any imbalances in the patient's 'life energy' or chi. Scientific instruments have been unable to detect this energy. The effect of TT on wound healing has been expounded in anecdotal publications.
OBJECTIVES
To identify and review all relevant data to determine the effects of TT on healing acute wounds.
SEARCH METHODS
In January 2014, for this fifth update, we searched The Cochrane Wounds Group Specialised Register; The Cochrane Central Register of Controlled Trials (CENTRAL) (The Cochrane Library); Ovid MEDLINE; Ovid MEDLINE (In-Process & Other Non-Indexed Citations); Ovid EMBASE; and EBSCO CINAHL.
SELECTION CRITERIA
All randomised or quasi-randomised controlled trials, which compared the effect of TT with a placebo, another treatment, or no treatment control were considered. Studies which used TT as a stand-alone treatment, or as an adjunct to other therapies, were eligible.
DATA COLLECTION AND ANALYSIS
One author (DO'M) determined the eligibility for inclusion of all trials in the review. Both authors conducted data extraction and evaluation of trial validity independently. Each trial was assessed using predetermined criteria.
MAIN RESULTS
No new trials were identified for this update. Four trials in people with experimental wounds were included. The effect of TT on wound healing in these studies was variable. Two trials (n = 44 & 24) demonstrated a significant increase in healing associated with TT, while one trial found significantly worse healing after TT and the other found no significant difference. All trials are at high risk of bias.
AUTHORS' CONCLUSIONS
There is no robust evidence that TT promotes healing of acute wounds.
Topics: Acute Disease; Bandages; Biopsy; Humans; Randomized Controlled Trials as Topic; Therapeutic Touch; Wound Healing
PubMed: 27552401
DOI: 10.1002/14651858.CD002766.pub5 -
Indian Journal of Critical Care... Jun 2016Yakson is a Korean therapeutic touch given to neonates and infants by caressing their abdomen with one hand while the other hand is placed on the back of the... (Review)
Review
Yakson is a Korean therapeutic touch given to neonates and infants by caressing their abdomen with one hand while the other hand is placed on the back of the neonate\infant either to relieve their pain or to calm them down. It was traditionally used by Koreans by caressing the aching body part of their children with a belief that it would relieve their pain. In spite of clinical evidence of its usefulness, there is limited literature available on Yakson touch. A systematic narrative review (SNR) was undertaken on studies that were carried out on the effectiveness of Yakson touch on infants and neonates. Only seven studies were detected from five major electronic databases, searched with the keywords: "Yakson," "Yakson touch," and "Yakson in neonates". One of the studies has been included in two Cochrane reviews by the same group of researchers published in 2011 and 2015, respectively, and also in a literature review. The evidence from these articles suggests that Yakson touch is able to increase the sleep scores of infants, affects their behavioral response, decreases the stress levels, increases maternal attachment, and has calming effects on them. However, the number of studies is limited, and thus the efficacy of this intervention has not been sufficiently established. Hence, there is a definite need for future studies to prove the efficacy of Yakson to include it in the early intervention programs. This SNR is aimed at compiling the studies which determined to prove the efficacy of the intervention of Yakson.
PubMed: 27390459
DOI: 10.4103/0972-5229.183897 -
The Cochrane Database of Systematic... May 2016Therapeutic Touch (TT) is an alternative therapy that has gained popularity over the past two decades for helping wounds to heal. Practitioners enter a meditative state... (Meta-Analysis)
Meta-Analysis Review
BACKGROUND
Therapeutic Touch (TT) is an alternative therapy that has gained popularity over the past two decades for helping wounds to heal. Practitioners enter a meditative state and pass their hands above the patient's body to find and correct any imbalances in the patient's 'life energy' or chi. Scientific instruments have been unable to detect this energy. The effect of TT on wound healing has been expounded in anecdotal publications.
OBJECTIVES
To identify and review all relevant data to determine the effects of TT on healing acute wounds.
SEARCH METHODS
In January 2014, for this fifth update, we searched The Cochrane Wounds Group Specialised Register; The Cochrane Central Register of Controlled Trials (CENTRAL) (The Cochrane Library); Ovid MEDLINE; Ovid MEDLINE (In-Process & Other Non-Indexed Citations); Ovid EMBASE; and EBSCO CINAHL.
SELECTION CRITERIA
All randomised or quasi-randomised controlled trials, which compared the effect of TT with a placebo, another treatment, or no treatment control were considered. Studies which used TT as a stand-alone treatment, or as an adjunct to other therapies, were eligible.
DATA COLLECTION AND ANALYSIS
One author (DO'M) determined the eligibility for inclusion of all trials in the review. Both authors conducted data extraction and evaluation of trial validity independently. Each trial was assessed using predetermined criteria.
MAIN RESULTS
No new trials were identified for this update. Four trials in people with experimental wounds were included. The effect of TT on wound healing in these studies was variable. Two trials (n = 44 & 24) demonstrated a significant increase in healing associated with TT, while one trial found significantly worse healing after TT and the other found no significant difference. All trials are at high risk of bias.
AUTHORS' CONCLUSIONS
There is no robust evidence that TT promotes healing of acute wounds.
Topics: Acute Disease; Bandages; Biopsy; Humans; Randomized Controlled Trials as Topic; Therapeutic Touch; Wound Healing
PubMed: 27140910
DOI: 10.1002/14651858.CD002766.pub4 -
Optimal nonpharmacological management of agitation in Alzheimer's disease: challenges and solutions.Clinical Interventions in Aging 2016Many patients with Alzheimer's disease will develop agitation at later stages of the disease, which constitutes one of the most challenging and distressing aspects of... (Review)
Review
Many patients with Alzheimer's disease will develop agitation at later stages of the disease, which constitutes one of the most challenging and distressing aspects of dementia. Recently, nonpharmacological therapies have become increasingly popular and have been proven to be effective in managing the behavioral symptoms (including agitation) that are common in the middle or later stages of dementia. These therapies seem to be a good alternative to pharmacological treatment to avoid unpleasant side effects. We present a systematic review of randomized controlled trials (RCTs) focused on the nonpharmacological management of agitation in Alzheimer's disease (AD) patients aged 65 years and above. Of the 754 studies found, eight met the inclusion criteria. This review suggests that music therapy is optimal for the management of agitation in institutionalized patients with moderately severe and severe AD, particularly when the intervention includes individualized and interactive music. Bright light therapy has little and possibly no clinically significant effects with respect to observational ratings of agitation but decreases caregiver ratings of physical and verbal agitation. Therapeutic touch is effective for reducing physical nonaggressive behaviors but is not superior to simulated therapeutic touch or usual care for reducing physically aggressive and verbally agitated behaviors. Melissa oil aromatherapy and behavioral management techniques are not superior to placebo or pharmacological therapies for managing agitation in AD. Further research in clinical trials is required to confirm the effectiveness and long-term effects of nonpharmacological interventions for managing agitation in AD. These types of studies may lead to the development of future intervention protocols to improve the well-being and daily functioning of these patients, thereby avoiding residential care placement.
Topics: Alzheimer Disease; Behavioral Symptoms; Disease Management; Humans; Music Therapy; Phototherapy; Psychiatric Status Rating Scales; Psychomotor Agitation; Randomized Controlled Trials as Topic
PubMed: 26955265
DOI: 10.2147/CIA.S69484 -
Cancer Jul 2015The widespread use of complementary and alternative medicine (CAM) in cancer survivors is well known despite a paucity of scientific evidence to support its use. The... (Review)
Review
The widespread use of complementary and alternative medicine (CAM) in cancer survivors is well known despite a paucity of scientific evidence to support its use. The number of survivors of hematopoietic stem cell transplant (HCT) is growing rapidly and HCT clinicians are aware that many of their patients use CAM therapies consistently. However, due to a paucity of data regarding the benefits and harms of CAM therapies in these survivors, clinicians are reluctant to provide specific recommendations for or against particular CAM therapies. A systematic literature review was conducted with a search using PubMed, the Cochrane Database of Systematic Reviews, and Ovid online for each CAM therapy as defined by the National Center of Complementary and Alternative Medicine. The search generated 462 references, of which 26 articles were deemed to be relevant for the review. Due to extensive heterogeneity in data and limited randomized trials, a meta-analysis could not be performed but a comprehensive systematic review was conducted with specified outcomes for each CAM therapy. In randomized controlled trials, certain mind and body interventions such as relaxation were observed to be effective in alleviating psychological symptoms in patients undergoing HCT, whereas the majority of the other CAM treatments were found to have mixed results. CAM use is an understudied area in HCT survivorship and clinicians should convey the benefits and uncertainties concerning the role of CAM therapies to their patients.
Topics: Acupuncture Therapy; Aromatherapy; Complementary Therapies; Exercise Movement Techniques; Hematopoietic Stem Cell Transplantation; Humans; Hypnosis; Manipulation, Spinal; Massage; Materia Medica; Meditation; Mind-Body Therapies; Minerals; Music Therapy; Plants, Medicinal; Probiotics; Qigong; Randomized Controlled Trials as Topic; Relaxation Therapy; Stress, Psychological; Survivors; Tai Ji; Therapeutic Touch; Uncertainty; Vitamins; Yoga
PubMed: 25872879
DOI: 10.1002/cncr.29382 -
Progres En Urologie : Journal de... Jun 2015In the absence of practice recommendations, it was realized a review of the literature to establish the epidemiological and bacteriological data, prevention of... (Review)
Review
OBJECTIVES
In the absence of practice recommendations, it was realized a review of the literature to establish the epidemiological and bacteriological data, prevention of infection, therapeutic attitude according to the clinical situation as well as the future prospects about the infections of penile prostheses.
METHODS
A systematic review of the scientific literature was realized by the base of Pubmed data (http://www.ncbi.nim.gov/pubmed/). The literature search was made between 1992 and 2014 using the keywords: penile prostheses, penile implant, infection. The article was developed according to the recommendations Preferred reporting items for systematic reviews and meta-analyses 2009 (Prisma).
RESULTS
The analysis of 10 meta-analysis and series published in various expert centers allowed us to synthesize the care recommended at present. Coagulasse négative staphylococcus were germs most frequently persons in charge but variations are secondarily observed in the current practices. The physiopathological knowledge (biofilm and risk factors) allowed to develop the antibiotic antibioprophylaxis, the precautionary measures of the infection of the operating site, the design of prostheses antimicrobial-impregnated or antibiotic-dipped and meticulous surgical technique ("Wash-Out", "No Touch"). In case of real infection, it was recommended in the absence of contra-indication to realize immediate salvage procedure allowing to set up a new penile prostheses, so avoiding the penile fibrosis.
CONCLUSION
All these measures have induced a decrease of the infection of penile implants significantly as well in case of primary implantation as of surgical revision. The future perspectives aim at preventing the infection by inhibition of the formation of the biofilm and by a more effective action of antibiotics about germs which it contains; or to use devices intrapenile "spacer" when the immediate salvage procedure is not feasible to facilitate the next implantation.
Topics: Anti-Bacterial Agents; Humans; Male; Penile Prosthesis; Prosthesis-Related Infections
PubMed: 25841759
DOI: 10.1016/j.purol.2015.02.006 -
The Cochrane Database of Systematic... Apr 2015Anxiety and depression affect many people. Treatments do not have complete success and often require people to take drugs for long periods of time. Many people look for... (Review)
Review
BACKGROUND
Anxiety and depression affect many people. Treatments do not have complete success and often require people to take drugs for long periods of time. Many people look for other treatments that may help. One of those is Reiki, a 2500 year old treatment described as a vibrational or subtle energy therapy, and is most commonly facilitated by light touch on or above the body. There have been reports of Reiki alleviating anxiety and depression, but no specific systematic review.
OBJECTIVES
To assess the effectiveness of Reiki for treating anxiety and depression in people aged 16 and over.
SEARCH METHODS
Search of the Cochrane Register of Controlled Trials (CENTRAL - all years), the Cochrane Depression, Anxiety and Neurosis Review Group's Specialised Register (CCDANCTR - all years), EMBASE, (1974 to November 2014), MEDLINE (1950 to November 2014), PsycINFO (1967 to November 2014) and AMED (1985 to November 2014). Additional searches were carried out on the World Health Organization Trials Portal (ICTRP) together with ClinicalTrials.gov to identify any ongoing or unpublished studies. All searches were up to date as of 4 November 2014.
SELECTION CRITERIA
Randomised trials in adults with anxiety or depression or both, with at least one arm treated with Reiki delivered by a trained Reiki practitioner.
DATA COLLECTION AND ANALYSIS
The two authors independently decided on inclusion/exclusion of studies and extracted data. A prior analysis plan had been specified but was not needed as the data were too sparse.
MAIN RESULTS
We found three studies for inclusion in the review. One recruited males with a biopsy-proven diagnosis of non-metastatic prostate cancer who were not receiving chemotherapy and had elected to receive external-beam radiation therapy; the second study recruited community-living participants who were aged 55 years and older; the third study recruited university students.These studies included subgroups with anxiety and depression as defined by symptom scores and provided data separately for those subgroups. As this included only 25 people with anxiety and 17 with depression and 20 more with either anxiety or depression, but which was not specified, the results could only be reported narratively. They show no evidence that Reiki is either beneficial or harmful in this population. The risk of bias for the included studies was generally rated as unclear or high for most domains, which reduces the certainty of the evidence.
AUTHORS' CONCLUSIONS
There is insufficient evidence to say whether or not Reiki is useful for people over 16 years of age with anxiety or depression or both.
Topics: Adult; Anxiety; Depression; Female; Humans; Male; Middle Aged; Prostatic Neoplasms; Randomized Controlled Trials as Topic; Therapeutic Touch
PubMed: 25835541
DOI: 10.1002/14651858.CD006833.pub2 -
Cancer Medicine Aug 2015Men with prostate cancer are likely to have a long illness and experience psychological distress for which supportive care may be helpful. This systematic review... (Meta-Analysis)
Meta-Analysis Review
Men with prostate cancer are likely to have a long illness and experience psychological distress for which supportive care may be helpful. This systematic review describes the evidence for effectiveness and cost-effectiveness of supportive care for men with prostate cancer, taking into account treatment pathway and components of interventions. MEDLINE, EMBASE, CINAHL, CENTRAL, and Psychinfo were searched from inception--July 2013 for randomized controlled trials and controlled trials. Two authors independently assessed risk of bias and extracted data. Twenty-six studies were included (2740 participants). Interventions were delivered pre and during (n = 12), short-term (n = 8), and longer term (18 months) (n = 5) after primary treatment. No interventions were delivered beyond this time. Few trials recruited ethnic minorities and none recruited men in same sex relationships. Intervention components included information, education, health professional discussion, homework, peer discussion, buddy support, cognitive behavioral therapy, cognitive restructuring, psychoeducation, Reiki and relaxation. Most interventions were delivered for 5-10 weeks. Risk of bias of trials was assessed as unclear for most domains due to lack of information. The majority of trials measuring quality of life and depression found no effect. Relatively few trials measured anxiety, coping skills and self-efficacy, and the majority found no effect. No cost data were available. Trials of supportive care for men with prostate cancer cover a range of interventions but are limited by population diversity, inconsistent measurement and reporting of outcomes, and inability to assess risk of bias. Recommendations on design and conduct of future trials are presented.
Topics: Adaptation, Psychological; Affect; Anxiety; Cost-Benefit Analysis; Depression; Humans; Male; Outcome Assessment, Health Care; Prostatic Neoplasms; Quality of Life; Randomized Controlled Trials as Topic; Self Efficacy
PubMed: 25828811
DOI: 10.1002/cam4.446