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Annals of the Rheumatic Diseases Aug 2000To consider the question: How strong is the evidence in favour of yttrium synovectomy in chronic knee arthritis in patients with rheumatoid arthritis in comparison with... (Review)
Review
OBJECTIVE
To consider the question: How strong is the evidence in favour of yttrium synovectomy in chronic knee arthritis in patients with rheumatoid arthritis in comparison with placebo and intra-articular steroid treatment?
METHODS
A systematic review of the literature was performed using Medline and the Embase database.
RESULTS
Initially, seven papers were identified, but only two met the inclusion criteria. Neither study showed evidence in favour of yttrium synovectomy.
CONCLUSION
From the point of view of evidence based medicine it should be seriously questioned whether yttrium synovectomy deserves a place in clinical practice.
Topics: Arthritis, Rheumatoid; Glucocorticoids; Humans; Injections, Intra-Articular; Knee Joint; Randomized Controlled Trials as Topic; Synovial Membrane; Treatment Outcome; Yttrium Radioisotopes
PubMed: 10913051
DOI: 10.1136/ard.59.8.583