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The Journal of Dermatology Oct 1987
Topics: Adult; Dermatomycoses; Female; Humans; Microsporum; Skin
PubMed: 3325539
DOI: 10.1111/j.1346-8138.1987.tb03611.x -
Arzneimittel-Forschung 1986Juliflorine, an alkaloid from Prosopis juliflora, was tested for its antifungal activity against the freshly isolated cultures of dermatophytic fungi and its inhibitory... (Comparative Study)
Comparative Study
Juliflorine, an alkaloid from Prosopis juliflora, was tested for its antifungal activity against the freshly isolated cultures of dermatophytic fungi and its inhibitory effect was compared with that of griseofulvin. The results indicated that the minimum inhibitory concentration (MIC) of juliflorine against Trichophyton rubrum, Trichophyton violaceum, Trichophyton mentagrophytes, Trichophyton tonsurans, Trichophyton megninii, Trichophyton gallinae, Microsporum canis, Microsporum nanum, Microsporum ferrugineum and Epidermophyton floccosum was 1.5 micrograms/ml, whereas that of griseofulvin was 0.1-0.5 microgram/ml. MIC of juliflorine for Candida albicans was 0.05 mg/ml. The alkaloid was also subjected to screening for carcinogenicity in the Ames test (salmonella/microsome test system). The results indicated that the compound in the recommended concentrations did not exhibit positive mutagenic reaction, as compared to a strong positive reaction by ethyl methane sulfonate based on his- ----his+ revertants.
Topics: Alkaloids; Antifungal Agents; Arthrodermataceae; Candida albicans; Carcinogens; Griseofulvin; Microsporum; Mutagenicity Tests; Nystatin; Trichophyton
PubMed: 3513775
DOI: No ID Found -
International Journal of Dermatology Oct 1984A study of the causative agents of tinea corporis and pedis in Puerto Rico in 1982 disclosed four different dermatophytes from a total of 97 cases. Among the total of 49...
A study of the causative agents of tinea corporis and pedis in Puerto Rico in 1982 disclosed four different dermatophytes from a total of 97 cases. Among the total of 49 fungus specimens collected in tinea corporis, the mycologic flora consisted of four different fungus species: Trichophyton rubrum, 42 isolates (85.7%); Epidermophyton floccosum, 4 (8.1%); Trichophyton mentagrophytes, 2 (4%); and Microsporum ferrugineum, 1 (2%). Among the total of 48 fungus specimens collected in tinea pedis, the mycologic flora consisted of 3 different fungus species as follows: T. rubrum, 35 isolates (72.9%); T. mentagrophytes 8 (16.6%); and E. floccosum, 5 (10.4%). Trichophyton rubrum caused 77 of 97 fungal isolates (79.3%). One surprising finding was the isolation of M. ferrugineum in a case of tinea corporis, documenting the first autochtonous case of this species in the island. This dermatophyte had previously been known only in Japan and adjacent areas of the Far East, Southern Europe, and Africa.
Topics: Adult; Epidermophyton; Humans; Microsporum; Middle Aged; Puerto Rico; Tinea; Tinea Pedis; Trichophyton
PubMed: 6500796
DOI: 10.1111/j.1365-4362.1984.tb04209.x -
Mycopathologia Mar 1984A survey of dermatophytes isolated from patients seeking medical advice was made from 1979 to 1981 in the United States. The survey included 54 locations with data from...
A survey of dermatophytes isolated from human patients in the United States from 1979 to 1981 with chronological listings of worldwide incidence of five dermatophytes often isolated in the United States.
A survey of dermatophytes isolated from patients seeking medical advice was made from 1979 to 1981 in the United States. The survey included 54 locations with data from 40 cities and 2 states. Correlations of these data with that of the other localities of the world were made to illustrate the dynamic epidemiology of several common dermatophytes. The most often isolated dermatophyte in this survey was Trichophyton rubrum having 53.66% of the total for these three calendar years. In a chronological listing of ringworm infections caused by this organism, many areas of the world have reported similar increased incidence of this pathogen. Trichophyton tonsurans was isolated 27.85% of the total. A dramatic increase of this pathogen as a cause of tinea capitis has been observed in most cities of the United States. It has been isolated in 25 different countries of the world. The percentage of isolation of Trichophyton mentagrophytes was 8.56%. This percentage may not be near the true incidence of infection by this dermatophyte because the infections are mild and respond to treatment without the individual seeking medical advice. Since the 1950s the percentage of isolations of the total has dropped for T. mentagrophytes in the United States. Epidermophyton floccosum accounted for 4.36% of the total. In a few areas of the world it causes over 30% of the total of dermatophytoses. Microsporum canis was isolated 3.72% of the total in the United States. It has recently been reported to be the dominant agent of tinea capitis in several South American countries, Tucson, Arizona and Kuwait. Once the dominant pathogen of tinea capitis in children in the United States, it was replaced by Microsporum audouinii before 1960. Today in the United States, M. audouinii only accounts for 0.30% of the total. It is considered eliminated as a pathogen in England. In this survey, isolated less than 1.0% of the total were Microsporum gypseum. Microsporum ferrugineum , Microsporum nanum , Microsporum fulvum and Trichophyton schoenleinii . Trichophyton meginii and Trichophyton terrestre were reported isolated but no numerical data were available.
Topics: Arthrodermataceae; Chronology as Topic; Dermatomycoses; Epidermophyton; Humans; Microsporum; Species Specificity; Trichophyton; United States
PubMed: 6727982
DOI: 10.1007/BF00436709 -
Mycopathologia Feb 1984A study, conducted with 20 isolates of Microsporum ferrugineum and 12 isolates of Trichophyton soudanense, revealed that some of the discrepancies in the literature...
A study, conducted with 20 isolates of Microsporum ferrugineum and 12 isolates of Trichophyton soudanense, revealed that some of the discrepancies in the literature regarding their characteristics and differentiation were due to methodology, strain variation and the use of an insufficient number of isolates. We found all isolates of T. soudanense to be urease negative and gelatinase positive (usually by the first week); to produce brown to black colonies on Lowenstein-Jensen medium; to rapidly decompose casein and more slowly tyrosine; to grow well or better at 37 degrees C as compared to room temperature; to produce reflexive branching on cornmeal Tween agar and abundant microconidia on casero medium and to exhibit no sexual reaction with either mating type of arthroderma simii. All but one isolate demonstrated restricted growth on lactose agar and only three isolates perforated hair. In contrast, we found 18 of 20 isolates of M. ferrugineum to be urease positive in urea broth (most isolates were negative on urea agar); all produced light-colored colonies on Lowenstein-Jensen medium; spreading colonies on lactose agar and failed to perforate hair in vitro or to produce reflexive branching. Most isolates manifested poorer to no growth at 37 degrees C compared to room temperature and all but one failed to decompose casein and tyrosine. A few strains produced macroconidia and/or microconidia on casero medium and some reacted sexually with A. simii (a) (-) mating type. Gelatin hydrolysis was variable.(ABSTRACT TRUNCATED AT 250 WORDS)
Topics: Culture Media; Dermatomycoses; Humans; Microbiological Techniques; Microsporum; Species Specificity; Tinea; Trichophyton
PubMed: 6371542
DOI: 10.1007/BF00436519 -
Mycopathologia Mar 1983Human hairs infected with Microsporum ferrugineum were examined by light and scanning electron microscopy to obtain information on the parasitic form. The fungus invaded...
Human hairs infected with Microsporum ferrugineum were examined by light and scanning electron microscopy to obtain information on the parasitic form. The fungus invaded the hair filaments and developed hyphae between the hair cuticles and cortex. Spheroids of arthroconidia were frequently observed to invade the hair follicle. A mosaic sheath of massive spheroids was observed around the hair filaments. The smooth-walled arthroconidia with chitinous surfaces were single, spherical or subspherical particles of 2.0-2.5 X 2.5-3.5 microns, and 2-celled, gourd-shaped (constricted at the septum) particles of 2.5-3.0 X 5.0-7.0 microns.
Topics: Child; Dermatomycoses; Female; Hair; Humans; Microscopy, Electron, Scanning; Microsporum
PubMed: 6888496
DOI: 10.1007/BF00436817 -
Mykosen Sep 1982
Topics: Child; Dermatomycoses; Germany, West; Humans; Male; Microsporum
PubMed: 7144810
DOI: No ID Found -
Der Hautarzt; Zeitschrift Fur... Jan 1978Observations by the author and other workers on exotic mycoses in Germany are used in order to establish several groups of patients. The following mycoses from tropical...
Observations by the author and other workers on exotic mycoses in Germany are used in order to establish several groups of patients. The following mycoses from tropical and subtropical areas and their causative agents are mentioned: Tinea nigra (Cladosporium werneckii), south American blastomycosis (Paracoccidioides brasiliensis), coccidioidomycosis (Coccidioides immitis), histoplasmosis (Histoplasma capsulatum), mycetoma (Madurella mycetomi), dermatophytosis/tinea capitis (Trichophyton soudanense, Trichophyton violaceum, Microsporum ferrugineum), sporotrichosis (Sporothrix schenckii), chromomycosis (Fonsecaea pedrosoi).
Topics: Blastomycosis; Coccidioidomycosis; Germany, West; Histoplasmosis; Humans; Mycoses; Sporotrichosis; Tinea Capitis; Travel; Tropical Climate
PubMed: 627480
DOI: No ID Found -
Ceskoslovenska Dermatologie Oct 1975
Topics: Black People; Child; Geography; Humans; Male; Microsporum; Tinea Capitis
PubMed: 1192473
DOI: No ID Found -
Canadian Journal of Microbiology Jun 1975A study of the influence of various concentrations of NaC1 on 21 species of dermatophytes and other keratolytic fungi was made. Based on the sensitivity of the species...
A study of the influence of various concentrations of NaC1 on 21 species of dermatophytes and other keratolytic fungi was made. Based on the sensitivity of the species to various concentrations of NaC1, it was possible to divide them into five groups. Microsporum ferrugineum and Trichophyton concentricum and T. tonsurans were the most sensitive to NaC1 and were inhibited by 5%. The greatest number of species were inhibited by 12% NaC1. The fungi most tolerant to NaC1 were M. cookei and M. nanum, and T. mentagrophytes, T. schoenleinii, and T. terrestre. These species were inhibited by 15%. NaC1 prevented any variant change in Epidermophyton floccosum, T. mentagrophytes, and M. gypseum, but promoted a change in phenotype in M. audouinii and M. cookei, and T. gallinae. It is suggested that the word "pleomorphism" be replaced by the term sterile albinism. This term refers to that kind of cultural change when there is no evidence of sporulation and the white fluffy mycelium consists of fine sterile hyphae. Sterile albino strains of E. floccosum were induced to form a macroconidia on Sabouraud cycloheximide chloramphenicol gentamicin agar (SCCGA) containing 3-5% NaC1. Also, M. audouinii formed microconidia and macroconidia in velvety growth cultured on SCCGA containing NaC1.
Topics: Epidermophyton; Microsporum; Phenotype; Sodium Chloride; Trichophyton
PubMed: 1148934
DOI: 10.1139/m75-110