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Journal of Pharmacy & Bioallied Sciences Jul 2023Developmental disturbances in the permanent dentition are commonly seen due to traumatic injuries to the primary teeth, especially intrusive and avulsion injuries of the...
Developmental disturbances in the permanent dentition are commonly seen due to traumatic injuries to the primary teeth, especially intrusive and avulsion injuries of the overlaying primary incisors. These disturbances may range from enamel discoloration or hypoplasia, crown/root dilaceration, odontoma-like malformation and eruption disturbances. Concrescence is extremely rare in anterior teeth. This case report describes a rare case that showed a concrescence of the unerupted maxillary right lateral incisor and maxillary central incisor with crown dilaceration. Awareness regarding early diagnosis and the consequences of untreated trauma to primary teeth should be emphasized.
PubMed: 37694081
DOI: 10.4103/jpbs.jpbs_133_23 -
Frontiers in Oral Health 2023Enamel Renal Syndrome (ERS) (OMIM # 204690) is a rare genetic condition characterised by hypoplastic amelogenesis imperfecta, failed tooth eruption, intra-pulpal...
Enamel Renal Syndrome (ERS) (OMIM # 204690) is a rare genetic condition characterised by hypoplastic amelogenesis imperfecta, failed tooth eruption, intra-pulpal calcifications, gingival enlargement and occasionally nephrocalcinosis. In this case series, we report on four unrelated patients with a confirmed molecular diagnosis of ERS ( pathogenic variants) from Sub-Saharan Africa. The pathognomonic oral profile of ERS was mostly fulfilled in these patients, with the notable addition of an odontoma in one patient. The cases presented a spectrum of phenotypic severity both dentally and systemically. One patient presented with nephrocalcinosis and abnormal kidney function, one had reduced kidney size with normal kidney function, and two had no renal abnormalities. Patients presenting with the oral profile of ERS should receive a prompt referral to a nephrologist and a geneticist. They should receive long-term management from a multidisciplinary medical and dental team.
PubMed: 37675434
DOI: 10.3389/froh.2023.1228760 -
Asian Pacific Journal of Cancer... Aug 2023Primordial odontogenic tumor is a rare odontogenic tumor reported for the first time in 2014. It was included in the latest edition of World Health Organization... (Review)
Review
BACKGROUND AND OBJECTIVE
Primordial odontogenic tumor is a rare odontogenic tumor reported for the first time in 2014. It was included in the latest edition of World Health Organization classification of Head and Neck Tumors as a new benign mixed epithelial-mesenchymal neoplasm. To date, 26 cases has been reported in literature. The aim of this study was to determine the possible presence of primordial odontogenic tumor in the previously diagnosed cases with myxoid stroma.
MATERIALS AND METHODS
This study was a retrospective descriptive study that was concluded in Oral and Maxillofacial Pathology Department, School of Dentistry, Tehran University of Medical Sciences. We reviewed all 19,380 cases from 19,66 to find the lesions with myxoid stroma which were in differential diagnosis with primordial odontogenic tumor. These cases should be associated with an impacted or unerupted tooth and belong to the patients under 20 years old.
RESULTS
We find 503 pericoronal lesions with myxoid stroma. Three cases were isolated after recut and reevaluation for finding fulfill histologic features. After immunohistochemical analysis, we find a new case of developing primordial odontogenic tumor associated with odontoma.
DISCUSSION
Primordial odontogenic tumor a recently described odontogenic tumor has a well-defined clinicopathological and immunohistochemical profile and should be differentiated from the others pericoronal lesions. It is the first time that this archival review has been done to find probable cases of primordial odontogenic tumor.
Topics: Humans; Young Adult; Adult; Retrospective Studies; Iran; Odontogenic Tumors; Diagnosis, Differential; Neoplasms, Glandular and Epithelial
PubMed: 37642073
DOI: 10.31557/APJCP.2023.24.8.2845 -
Cureus Jul 2023Hamartomas are tumor-like abnormalities typified by the presence of cellular proliferation indigenous to the native site. However, hamartomas maintain growth cessation...
Hamartomas are tumor-like abnormalities typified by the presence of cellular proliferation indigenous to the native site. However, hamartomas maintain growth cessation without the potential for further growth or malignant transformation. Hamartomas are commonly seen in the lungs, kidney, liver, and spleen and rarely occur in the orofacial region. Various hamartomatous oral lesions include hemangiomas, lymphangiomas, tori, exostosis, dens invaginatus, dens evaginatus, odontomas, nevi, and cherubism. Infantile hemangiomas are benign vascular tumors that emerge soon after birth and experience rapid growth within the first year. Oral hemangiomas affect up to 6.4% of infants and are more common on the ventral surface of the tongue, as opposed to oral vascular malformations, which are more prevalent on the lips. It also has a 3:1 female-to-male predominance. Afterward, their growth usually stabilizes and enters a prolonged, incomplete involution phase. Uncomplicated hemangiomas generally exhibit spontaneous resolution, whereas few can leave behind scars and telangiectasias on the external surface of the skin on which it occurs. Thus, lesions located in anatomically sensitive regions necessitate vigilant surveillance and treatment. This paper deals with an asymptomatic swelling of the upper lip in a four-year-old female child but with problems in aesthetics, speech, and feeding. A thorough history, clinical examination, positive diascopy, ultrasonography, and histopathology confirmed the diagnosis of infantile hemangioma.
PubMed: 37637601
DOI: 10.7759/cureus.42556 -
Cureus Jul 2023Odontomas are the most common odontogenic neoplasms. They are generally small and asymptomatic. This article presents an unusual case of a giant maxillary complex...
Odontomas are the most common odontogenic neoplasms. They are generally small and asymptomatic. This article presents an unusual case of a giant maxillary complex odontoma, which obscured a part of the maxillary antrum and impacted a tooth. This was discovered during an episode of maxillofacial cellulitis. In this case, surgical excision of the lesion was performed under general anesthesia, and the closure was performed with a fat pad pedicled flap. A brief review of the literature was performed to analyze the characteristics of this clinical entity and their implication in the treatment.
PubMed: 37637586
DOI: 10.7759/cureus.42546 -
Congenital Anomalies Sep 2023Forensic odontology plays a crucial role in establishing the identity in mass disasters and criminal cases with high accuracy. Dental anomalies and features help in such... (Review)
Review
Forensic odontology plays a crucial role in establishing the identity in mass disasters and criminal cases with high accuracy. Dental anomalies and features help in such situations. Congenital and developmental dental anomalies can be easily documented to establish distinctive and individualistic characteristics of an individual. The location, number of teeth involved, and the type of anomaly vary between individuals. Similarly, dental malformations also assist greatly in the identification process. Many types of dental anomalies have been studied in the past for their individualistic characteristics in forensic examinations. One such dental anomaly is odontoma, which is a benign odontogenic malformation. This malformation may also help in the identification of the deceased, when recorded and examined accurately. An odontome is a malformed teeth-like structures consisting of enamel, dentin, and pulpal tissue, formed due to the growth of completely differentiated epithelial and mesenchymal cells. If antemortem (AM) dental records incorporate information regarding odontomes and other dental anomalies, including in radiographs, orthopantomograms or microradiographs, positive identification may be established by comparison of these records with postmortem (PM) records. In the present communication, a rare case of compound composite odontoma in the anterior mandible with multiple denticles has been discussed with a brief overview of congenital and developmental dental anomalies. The authors emphasize the importance of such rare dental anomalies and malformations which may be used for identifying the deceased in mass disasters and forensic identification.
Topics: Humans; Odontoma; Forensic Dentistry; Radiography, Panoramic; Tooth; Mandible
PubMed: 37503819
DOI: 10.1111/cga.12533 -
Imaging Science in Dentistry Jun 2023Odontomas represent a common clinical entity among odontogenic tumors, but are not well-addressed in the Vietnamese population. The present study aimed to determine the...
PURPOSE
Odontomas represent a common clinical entity among odontogenic tumors, but are not well-addressed in the Vietnamese population. The present study aimed to determine the clinical and preclinical characteristics of odontomas and associated factors in the Vietnamese population.
MATERIALS AND METHODS
This retrospective study retrieved data from histopathological diagnoses from 2 central hospitals of Odonto-Stomatology in Ho Chi Minh City, Vietnam during 2004-2017. The odontomas were classified as complex (CxOD) or compound (CpOD) subtypes. The epidemiological, clinical, and radiological characteristics of the odontomas, stratified by subtype and sex, were obtained and analyzed.
RESULTS
Ninety cases, consisting of 46 CxODs and 44 CpODs, were included. The average age of patients was 32.4 (±20.2) years. The patients with CxOD were older than those with CpOD (<0.05). Clinically, 67% of patients showed an intraoral bone expansion. Approximately 60% of patients with CxOD exhibited a painful symptom, about 3-fold more than those with CpOD (<0.05), whereas almost all patients with CpOD exhibited perturbations of dentition, unlike those with CxOD (<0.05). Radiologically, CxOD was characterized by a larger dimension than CpOD in both sexes (<0.05), and CpOD induced complications in adjacent teeth more often than CxOD (<0.05). The development of odontoma with advancing age differed significantly in odontoma subtypes related to their pathological origins, and between the sexes, resulting from different physiological states.
CONCLUSION
The findings of this study highlight the value of clinical and radiological features of odontomas and their associated factors for the early diagnosis and adequate treatment of younger patients.
PubMed: 37405206
DOI: 10.5624/isd.20220184 -
Journal of Veterinary Dentistry Jul 2024A 7-month-old, male, Weimaraner dog was presented for maxillary swelling. Clinical evaluation including radiographs and computed tomography revealed a large cystic...
A 7-month-old, male, Weimaraner dog was presented for maxillary swelling. Clinical evaluation including radiographs and computed tomography revealed a large cystic lesion, unerupted right maxillary canine tooth, and mass presumed to be a compound odontoma. The cyst and mass were expansile and occupied a large portion of the nasal cavity displacing anatomical structures of the maxilla. The mass was excised via curettage through an intraoral surgical approach and the unerupted tooth and cystic lining were removed. Histopathology supported dentigerous cyst and compound odontoma. This case confirms the first report of concurrent development of dentigerous cyst and compound odontoma in a dog with successful treatment and 18-month follow-up with no recurrence.
Topics: Animals; Dentigerous Cyst; Odontoma; Male; Dog Diseases; Dogs; Tooth, Unerupted; Cuspid; Maxillary Neoplasms
PubMed: 37337717
DOI: 10.1177/08987564231181053 -
Quintessence International (Berlin,... Sep 2023Dentinogenic ghost cell tumor (DGCT) is an uncommon odontogenic tumor considered to be the solid, tumorous variant of calcifying odontogenic cyst. DGCT is characterized... (Review)
Review
Dentinogenic ghost cell tumor (DGCT) is an uncommon odontogenic tumor considered to be the solid, tumorous variant of calcifying odontogenic cyst. DGCT is characterized by islands of ameloblastoma-like epithelial cells that resemble the enamel organ, the presence of ghost cells, and dentinoid material. This article reports a rare case of dentinogenic ghost cell tumor associated with an odontoma in an adult patient, with a review of the literature. To the best of the authors' knowledge, there have only been four case reports of DGCT associated with odontoma, all of which occurred in children and adults younger than 30 years old.
Topics: Adult; Child; Humans; Odontoma; Odontogenic Tumors; Odontogenic Cyst, Calcifying; Ameloblastoma
PubMed: 37313575
DOI: 10.3290/j.qi.b4157337 -
Minerva Dental and Oral Science Feb 2024The objectives of the study are to employ modified Gallego staining in pathology and to specifically evaluate the hard tissue apposed to odontogenic epithelium in order...
BACKGROUND
The objectives of the study are to employ modified Gallego staining in pathology and to specifically evaluate the hard tissue apposed to odontogenic epithelium in order to aid in the diagnosis.
METHODS
Lillie's modification of Gallego's stain was utilized as a reference to create a fresh batch of the stain. The archival and running cases of 2021-2022 was screened for odontogenic pathologies, yielding approximately 46 cases, among these four cases were selected which required evaluation of the hard tissue matrix apposed to odontogenic epithelium for its characterization. The modified Gallego staining was employed in the soft tissue sections of these cases under controlled environment. The staining results were evaluated.
RESULTS
The stain was used in cases to stain dentinoid deposition as green color in hybrid ameloblastoma, archegonous cystic odontoma, dentinogenic ghost cell tumor and also in other cases like calcifying odontogenic cyst. Bone presented as green in color, cells as pink color and collagen as green-pink. This helped in the correct diagnosis of these cases facilitating the correct treatment modality.
CONCLUSIONS
In the field of oral pathology, there are a multitude of lesions which are odontogenic with the diagnosis of few of them hinging on the characterization of hard tissue matrix found in close approximation to odontogenic epithelium implying an inductive capability to the odontogenic epithelium. This particular modified Gallego stain has been able to help in diagnosis of few such cases in our repertoire of cases.
Topics: Odontogenic Tumors; Ameloblastoma; Odontoma; Odontogenic Cyst, Calcifying; Staining and Labeling; Citrus
PubMed: 37310195
DOI: 10.23736/S2724-6329.23.04809-X