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JAMA Dermatology May 2020
Topics: Child, Preschool; Diagnosis, Differential; Female; Humans; Lower Extremity; Pagetoid Reticulosis; Skin
PubMed: 32129789
DOI: 10.1001/jamadermatol.2020.0059 -
The American Journal of Dermatopathology Sep 2020Pseudocarcinomatous hyperplasia (PCH) is a benign reactive epithelial proliferation that may be associated to lymphomas of the skin or external mucous membranes. We... (Review)
Review
Pseudocarcinomatous Hyperplasia, Squamous Cell Carcinoma, and Keratoacanthoma Associated to Lymphomas of the Skin and External Mucous Membranes: A Case Report and Literature Review.
Pseudocarcinomatous hyperplasia (PCH) is a benign reactive epithelial proliferation that may be associated to lymphomas of the skin or external mucous membranes. We present a case of single lesion mycosis fungoides (Woringer-Kollop's reticulosis pagetoid) associated with PCH that was initially misdiagnosed as squamous cell carcinoma (SCC) and review all PubMed-indexed previously reported cases on lymphomas of the skin or external mucous membranes associated to PCH, SCC, and keratoacanthomas. Including our own case, we collected data of 114 cases of cutaneous or mucosal lymphoproliferative disorders associated to PCH, 3 cases associated to SCC, and other 3 cases associated to keratoacanthomas. All cases were tabulated to the following parameters whenever data was available: sex, age, previous medical conditions, number of lesions (single × multiple), site of involvement (mucosa, skin or both), clinical impression, initial equivocal histopathologic diagnosis, final diagnosis, keratinocytic atypia (presence × absence), lymphocytic atypia (presence × absence), CD30-status, and treatment.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Biomarkers, Tumor; Biopsy; Carcinoma, Squamous Cell; Child; Diagnostic Errors; Female; Humans; Hyperplasia; Immunohistochemistry; Keratoacanthoma; Male; Middle Aged; Mucous Membrane; Pagetoid Reticulosis; Predictive Value of Tests; Skin; Skin Neoplasms; Young Adult
PubMed: 31833842
DOI: 10.1097/DAD.0000000000001587 -
Journal of Cutaneous Pathology May 2020Pagetoid reticulosis (PR) is a rare lymphoproliferative disorder with indolent behavior considered a variant of mycosis fungoides. It is characterized by marked... (Review)
Review
Pagetoid reticulosis (PR) is a rare lymphoproliferative disorder with indolent behavior considered a variant of mycosis fungoides. It is characterized by marked epidermotropism of the neoplastic lymphocytes. Since its original description, five cases have been reported in children. We report a new case of PR with an immunohistochemical profile not previously described in children.
Topics: Administration, Topical; Adolescent; Biopsy; Child; Child, Preschool; Clobetasol; Female; Glucocorticoids; Humans; Immunohistochemistry; Immunophenotyping; Lymphocytes; Lymphoproliferative Disorders; Male; Mycosis Fungoides; Pagetoid Reticulosis; Skin; Skin Neoplasms; Treatment Outcome
PubMed: 31785005
DOI: 10.1111/cup.13622 -
Photodermatology, Photoimmunology &... Sep 2019Pagetoid reticulosis (PR), also known as Woringer-Kolopp disease, is a rare variant of mycosis fungoides with distinctive clinicopathologic features. It clinically...
Pagetoid reticulosis (PR), also known as Woringer-Kolopp disease, is a rare variant of mycosis fungoides with distinctive clinicopathologic features. It clinically manifests as a solitary, erythematous, gradually enlarging, scaly, or verrucous plaque on the lower extremities, and due to its indolent course and nonspecific clinical features, may remain undiagnosed for years. In the current study, we describe the clinical and dermoscopic characteristics of a rare case of PR disease and correlate them with the corresponding histopathologic findings. Dermoscopy may prove beneficial in early diagnosis of this rare entity.
Topics: Aged; Dermoscopy; Humans; Male; Pagetoid Reticulosis; Skin; Skin Neoplasms
PubMed: 31006145
DOI: 10.1111/phpp.12472 -
Indian Journal of Pathology &... 2019Pagetoid reticulosis is an indolent cutaneous T-cell lymphoma and presents as erythema or plaque with a well-defined border on the distal areas of the extremities....
Pagetoid reticulosis is an indolent cutaneous T-cell lymphoma and presents as erythema or plaque with a well-defined border on the distal areas of the extremities. Immunophenotypic studies show that in most cases, neoplastic lymphocytes are positive for CD4, whereas CD20 and CD30 double positivity was rarely reported. In this paper, we report an 80-year-old woman who presented with erythema on the extremities for 3 years. Skin biopsy on the right forearm was performed. Histopathologically, the erythematous lesions were characterized by atypical lymphocytes with significant epidermotropism. Immunohistochemical staining showed high proliferation as evidenced by high Ki-67 index and that the tumor cells were positive for CD20 and CD30 but negative for CD7 and CD56. The patient was treated with one cycle of radiotherapy and is currently doing well.
Topics: Aged, 80 and over; Antigens, CD20; Biopsy; Erythema; Female; Humans; Immunophenotyping; Ki-1 Antigen; Lymphocytes; Lymphoma, T-Cell, Cutaneous; Pagetoid Reticulosis; Skin; Skin Neoplasms; Treatment Outcome
PubMed: 30971566
DOI: 10.4103/IJPM.IJPM_717_18 -
JAAD Case Reports Jan 2019
PubMed: 30581947
DOI: 10.1016/j.jdcr.2018.10.023 -
The Veterinary Clinics of North... Jan 2019Cutaneous lymphomas are divided into categories based on histologic evaluation of the skin and location of neoplastic lymphocytes. Epitheliotropic cutaneous lymphoma,... (Review)
Review
Cutaneous lymphomas are divided into categories based on histologic evaluation of the skin and location of neoplastic lymphocytes. Epitheliotropic cutaneous lymphoma, also known as cutaneous T-cell lymphoma, is diagnosed when neoplastic lymphocytes show tropism for the epidermis and these cells infiltrate the epidermis and adnexae. In diagnosis of nonepitheliotropic cutaneous lymphoma, neoplastic lymphocytes are found mostly in the dermis and/or subcutis. Neoplastic cells are of either B-cell or T-cell origin. This article focuses on epitheliotropic cutaneous lymphomas and cutaneous lymphocytosis, which is considered a form of indolent lymphoma, in dogs and cats.
Topics: Animals; Cat Diseases; Cats; Lymphocytosis; Lymphoma, T-Cell, Cutaneous; Skin Neoplasms; Veterinary Medicine
PubMed: 30262145
DOI: 10.1016/j.cvsm.2018.08.007 -
Journal of the European Academy of... Oct 2018
Topics: Aged; Dermoscopy; Humans; Male; Pagetoid Reticulosis
PubMed: 29730881
DOI: 10.1111/jdv.15059 -
The American Journal of Dermatopathology Mar 2018
Topics: Adult; Foot; Humans; Male; Pagetoid Reticulosis; Skin Neoplasms
PubMed: 29470305
DOI: 10.1097/DAD.0000000000000866 -
Cutis May 2017
Topics: Aged, 80 and over; Carcinoma, Squamous Cell; Diagnosis, Differential; Foot Dermatoses; Humans; Male; Melanoma; Pagetoid Reticulosis; Skin Neoplasms
PubMed: 28632799
DOI: No ID Found