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Luminescence : the Journal of... Dec 2023It is of great significance to develop an effective method for methyl parathion (MP) detection. Herein, a novel nitrogen-doped titanium carbide quantum dots (N-Ti C QDs)...
It is of great significance to develop an effective method for methyl parathion (MP) detection. Herein, a novel nitrogen-doped titanium carbide quantum dots (N-Ti C QDs) was prepared and used to construct a simple and sensitive fluorescence sensing platform of MP by making use of inner filter effect (IFE). The prepared N-Ti C QDs can exhibit strong blue fluorescence at 434 nm. Meanwhile, MP could hydrolyze to produce p-nitrophenol (p-NP) under alkaline conditions, which showed a characteristic ultraviolet-visible (UV-visible) absorption peak at 405 nm, resulting in the fluorescence of N-Ti C QDs is effectively quenched by p-NP. In addition, the investigation of time-resolved fluorescence decays indicated that the corresponding quenching mechanism of p-NP on N-Ti C QDs is due to the IFE. After optimizing the conditions, the as-developed fluorescence sensing platform displayed wide detection range (0.1-30 μg mL ) and low detection limit (0.036 μg mL ) for MP, and it was also successfully applied for MP analysis in real water samples, thus it is expected that this simple, sensitive and enzyme-free sensing platform shows great applications.
PubMed: 38148625
DOI: 10.1002/bio.4632 -
ACS Omega Dec 2023Exfoliated kaolinite nanosheets (EXK) and their hybridization with β-cyclodextrin (β-CD/EXK) were evaluated as potential-enhanced adsorbents of methyl parathion (MP)...
Advanced Equilibrium Modeling for the Synergetic Effect of β-Cyclodextrin Integration on the Adsorption Efficiency of Methyl Parathion by β-Cyclodextrin/Exfoliated Kaolinite Nanocomposite.
Exfoliated kaolinite nanosheets (EXK) and their hybridization with β-cyclodextrin (β-CD/EXK) were evaluated as potential-enhanced adsorbents of methyl parathion (MP) in synergetic investigations to determine the effects of the different modification procedures. The adsorption behaviors were described on the basis of the energetic steric and energetic factors of the specific advanced equilibrium models (monolayer model of one energy). The functionalization process with β-CD enhanced the adsorption behaviors of MP considerably to 350.6 mg/g in comparison to EXK (291.7 mg/g) and natural kaolinite (K) (244.7 mg/g). The steric studies revealed a remarkable improvement in the quantities of the existing receptors after exfoliation ( = 134.4 mg/g) followed by β-CD hybridization ( = 162.3 mg/g) as compared to K (75.7 mg/g), which was reflected in the determined adsorption capacities of MP. Additionally, each active free site of β-CD/EXK can adsorb about 3 molecules of MP, which occur in a vertical orientation by types of multimolecular mechanisms. The energetic investigations of Gaussian energy (<8.6 kJ/mol) and adsorption energy (<40 kJ/mol) validate the physical adsorption of MP, which might involve the cooperation of dipole bonding forces, van der Waals, and hydrogen bonding. The properties and entropy values, free enthalpy, and intern energy as the investigated thermodynamic functions declared the exothermic and spontaneous behaviors of the MP adsorption.
PubMed: 38144066
DOI: 10.1021/acsomega.3c07088 -
Environmental Pollution (Barking, Essex... Feb 2024Organophosphorus pesticides (OPPs) such as parathion have extensive uses in agriculture and household applications. Chronic exposure to these pesticides can cause severe...
Organophosphorus pesticides (OPPs) such as parathion have extensive uses in agriculture and household applications. Chronic exposure to these pesticides can cause severe health and environmental issues. Therefore, a current ecological concern is associated with accumulating these noxious OPPs in food and water sources. In this work, a new Tb-doped Zn-LMOF (Zn-LMOF= (3D) {[Zn(1,4 benzenedicarboxylate)(EtOH)]·(EtOH)0.6}) was synthesized by a solvent-free reaction between the Zn-LMOF and the salt TbCl6HO using a high-speed ball milling. The Tb@Zn-LMOF was thoroughly characterized by multiple spectroscopic tools, including Scanning Electron Microscopy with Energy-Dispersive X-ray Spectroscopy, and studied in-depth as a luminescent sensor for a series of pesticides (parathion, malathion, methalaxil, carbofuran, iprodione, captan and glyphosate) in aqueous methanol. The Tb@Zn-LMOF is a long-lived green-emitting compound with luminescence originated by an efficient antenna effect from the excited energy levels of Zn-LMOF toward the 5D state of Tb ions, as it is displayed by its strong emission bands at 488, 545, 585, and 620 nm and a lifetime of 1.01 ms upon excitation at 290 nm. Additions of pesticides to a neutral methanolic dispersion of Tb@Zn-LMOF modified its green emission intensity with a pronounced selectivity toward parathion within the micromolar concentration range. The detection limit for parathion was calculated to be 3.04 ± 0.2 μM for Tb@Zn-LMOF. Based on P NMR and mass spectrometry studies, it is attributed to the release of lanthanide ions from Tb@Zn-LMOF with the simultaneous formation of a Tb-parathion complex.
Topics: Metal-Organic Frameworks; Luminescence; Pesticides; Parathion; Organophosphorus Compounds; Ions; Zinc
PubMed: 38142811
DOI: 10.1016/j.envpol.2023.123195 -
Journal of Environmental Management Feb 2024Food safety is an important issue of most concern for health, while pesticides are one of the main threats to food safety. In view of the potential health hazard of...
Food safety is an important issue of most concern for health, while pesticides are one of the main threats to food safety. In view of the potential health hazard of pesticides in food, the cancer and non-cancer risks were assessed for 19 kinds of pesticides in Chinese food in this study. Furthermore, the health risks of different types of pesticides were compared to uncover the most polluted pesticide types in this study. Results show that methyl parathion, dichlorvos and 2,4-D residues in some food groups exceed the Chinese food standards. The cumulative disease burden of six carcinogenic pesticides for people older than 40 years ranges from 1.03 × 10 to 2.27 × 10, which exceeds the WHO recommended limit of 10. The non-cancer risks of 13 kinds of pesticides are all lower than 1 and will not pose appreciable health risk to the consumers. Livestock and poultry (contribution rate = 38.93%) and Milk and dairy products (contribution rate = 22.38%) are the dominate risk exposure sources for carcinogenic pesticides while staple foods (contribution rate = 31.62%) and vegetables (contribution rate = 21.5%) are the main risk exposure sources for non-carcinogenic pesticides. Comparing the risks of different pesticide types, insecticide is the most harmful category in this study, followed by herbicide and acaricide. This study characterized the health risks of pesticides in Chinese food and provided a scientific basis for pesticide management.
Topics: Humans; Pesticides; Pesticide Residues; Insecticides; Vegetables; Food Contamination; Risk Assessment; Neoplasms
PubMed: 38128207
DOI: 10.1016/j.jenvman.2023.119813 -
Environmental Research Feb 2024Organophosphates pesticide (OP) toxicity through water resources is a large concern globally among all the emerging pollutants. Detection of OPs is a challenge which...
Recombinant Organophosphorus acid anhydrolase (OPAA) enzyme-carbon quantum dot (CQDs)-immobilized thin film biosensors for the specific detection of Ethyl Paraoxon and Methyl Parathion in water resources.
Organophosphates pesticide (OP) toxicity through water resources is a large concern globally among all the emerging pollutants. Detection of OPs is a challenge which needs to be addressed considering the hazardous effects on the health of human beings. In the current research thin film biosensors of recombinant, Organophosphorus acid anhydrolase (OPAA) enzyme along with carbon quantum dots (CQDs) immobilized in thin films were developed. OPAA-CQDs thin film biosensors were used for the specific detection of two OPs Ethyl Paraoxon (EP) and Methyl Parathion (MP) in river water and household water supply. Recombinant OPAA enzyme was expressed in E. Coli, purified and immobilized on the CQD containing chitosan thin films. The CQDs used for this purpose were developed by a one-pot hydrothermal method from phthalic acid and Tri ethylene diamine. The properties of CQDs, OPAA and thin films were characterized using techniques like XPS, TEM, XRD, enzyme activity and CLSM measurements. Biosensing studies of EP and MP were performed by taking fluorescence measurements using a fiber optic spectrometer. The analytical parameters of biosensing were compared against an estimation carried out using the HPLC method. The biosensing performance indicates that the OPAA-CQDs thin film-based biosensors were able to detect both EP and MP in a range of 0-100 μM having a detection limit of 0.18 ppm/0.69 ppm for EP/MP, respectively with a response time of 5 min. The accuracy of estimation of EP/MP when spiked in water resources lie in the range of ∼100-102% which clearly indicates the OPAA-CQD based thin film biosensors can function as a point-of-use method for the detection of OP pesticides in complex water resources.
Topics: Humans; Paraoxon; Aryldialkylphosphatase; Methyl Parathion; Quantum Dots; Carbon; Water Resources; Escherichia coli; Pesticides; Parathion; Biosensing Techniques
PubMed: 38070850
DOI: 10.1016/j.envres.2023.117855 -
Analytical Biochemistry Mar 2024Core-shell ZIF-8@ZIF-67 was synthesized by growing a cobalt-based ZIF-67 on a ZIF-8 seed particle. Herein, through selective etching of the ZIF-8@ZIF-67 core and...
Core-shell ZIF-8@ZIF-67 was synthesized by growing a cobalt-based ZIF-67 on a ZIF-8 seed particle. Herein, through selective etching of the ZIF-8@ZIF-67 core and subsequent direct carbonization, core-shell hollow ZnO@CoO nitrogen-doped nanoporous carbon (HZnO@CoO-NPC) nanocomposites were prepared. HZnO@CoO-NPCs possessed a high nitrogen content, large surface area, high degree of graphitization and excellent electrical conductivity, all of which were attributed to successfully integrating the unique advantages of ZIF-8 and ZIF-67. HZnO@CoO-NPCs were used to assemble acetylcholinesterase (AChE) biosensors for organophosphorus pesticides (OPs) detection. The low detection limit of 2.74 × 10 M for chlorpyrifos and 7.6 × 10 M for parathion-methyl demonstrated the superior sensing performance. The results showed that the electrochemical biosensor constructed by HZnO@CoO-NPC provided a sensitive and efficient electrochemical strategy for OPs detection.
Topics: Organophosphorus Compounds; Pesticides; Zinc Oxide; Nitrogen; Acetylcholinesterase; Insecticides; Methyl Parathion; Biosensing Techniques; Nanocomposites
PubMed: 38070664
DOI: 10.1016/j.ab.2023.115422 -
Molecules (Basel, Switzerland) Nov 2023An unprecedented photocatalyst, SmEuSbO, was successfully fabricated in this paper, through a high-temperature solid-state calcination method, which represented its...
An unprecedented photocatalyst, SmEuSbO, was successfully fabricated in this paper, through a high-temperature solid-state calcination method, which represented its first ever synthesis. Additionally, using the solvothermal method, the SmEuSbO/ZnBiSbO heterojunction photocatalyst (SZHP) was fabricated, marking its debut in this study. XRD analysis confirmed that both SmEuSbO and ZnBiSbO exhibited pyrochlore-type crystal structures with a cubic lattice, belonging to the Fd3m space group. The crystal cell parameter was determined to be 10.5682 Å or 10.2943 Å for SmEuSbO or ZnBiSbO, respectively. The band gap width measured for SmEuSbO or ZnBiSbO was 2.73 eV or 2.61 eV, respectively. Under visible light irradiation for 150 min (VLTI-150 min), SZHP exhibited remarkable photocatalytic activity, achieving 100% removal of parathion methyl (PM) concentration and 99.45% removal of total organic carbon (TOC) concentration. The kinetic constant () for PM degradation and visible light illumination treatment was determined to be 0.0206 min, with a similar constant of 0.0202 min observed for TOC degradation. Remarkably, SZHP exhibited superior PM removal rates compared with SmEuSbO, ZnBiSbO, or N-doped TiO photocatalyst, accompanied by removal rates 1.09 times, 1.20 times, or 2.38 times higher, respectively. Furthermore, the study investigated the oxidizing capability of free radicals through the use of trapping agents. The results showed that hydroxyl radicals had the strongest oxidative capability, followed by superoxide anions and holes. These findings provide a solid scientific foundation for future research and development of efficient heterojunction compound catalysts.
PubMed: 38067453
DOI: 10.3390/molecules28237722 -
Chemosphere Jan 2024This article presents a novel and highly efficient electrocatalytic degradation method for two significant organophosphorus pesticides, fenitrothion (FEN), and methyl...
Boosted electrocatalytic oxidation of organophosphorus pesticides by a novel high-efficiency CeO-Doped PbO anode: An electrochemical study, parameter optimization and degradation mechanisms.
This article presents a novel and highly efficient electrocatalytic degradation method for two significant organophosphorus pesticides, fenitrothion (FEN), and methyl parathion (MPN), using a Ti/β-PbO-CeO modified anode (indirect oxidation). A comprehensive electrochemical investigation was also carried out to gain new insight into the redox behavior and destruction pathway of these pesticides (direct oxidation). The study also explores the effects of various operating parameters, such as initial solution pH, applied current density, and initial pesticides concentration, on the conversion-paired electrocatalytic removal process. To further enhance the degradation efficiency, a new configuration of the electrochemical cell was designed, employing two types of electrodes and two independent power supply devices. The conversion paired electrocatalytic degradation process of these pesticides involves first the direct reduction of FEN (or MPN) on a graphite cathode and then the indirect oxidation of reduced FEN (or MPN) by hydroxyl radicals electro generated on the Ti/β-PbO-CeO anode. The synergism of these two processes together will effectively lead to FEN (or MPN) degradation. The degradation percentages of 98% for FEN and 95% for MPN at the optimal conditions for the electrochemical degradation of these pesticides were achieved at pH = 7, initial concentration 50 mg L, with a current density of 90 mA cm for direct reduction and 11 mA cm for indirect oxidation. Overall, this study presents a promising and efficient approach for the remediation of organophosphorus pesticide-contaminated environments, offering valuable insights into the electrochemical degradation process and highlighting the potential for practical application in wastewater treatment and environmental protection.
Topics: Pesticides; Organophosphorus Compounds; Oxides; Oxidation-Reduction; Methyl Parathion; Electrodes; Titanium; Water Pollutants, Chemical
PubMed: 37925025
DOI: 10.1016/j.chemosphere.2023.140597 -
Toxics Sep 2023New approach methods (NAMs) can reduce the need for chronic animal studies. Here, we apply benchmark dose (concentration) (BMD(C))-response modeling to transcriptomic...
New approach methods (NAMs) can reduce the need for chronic animal studies. Here, we apply benchmark dose (concentration) (BMD(C))-response modeling to transcriptomic changes in the liver of mice and in fathead minnow larvae after short-term exposures (7 days and 1 day, respectively) to several dose/concentrations of three organophosphate pesticides (OPPs): fenthion, methidathion, and parathion. The mouse liver transcriptional points of departure (TPODs) for fenthion, methidathion, and parathion were 0.009, 0.093, and 0.046 mg/Kg-bw/day, while the fathead minnow larva TPODs were 0.007, 0.115, and 0.046 mg/L, respectively. The TPODs were consistent across both species and reflected the relative potencies from traditional chronic toxicity studies with fenthion identified as the most potent. Moreover, the mouse liver TPODs were more sensitive than or within a 10-fold difference from the chronic apical points of departure (APODs) for mammals, while the fathead minnow larva TPODs were within an 18-fold difference from the chronic APODs for fish species. Short-term exposure to OPPs significantly impacted acetylcholinesterase mRNA abundance (FDR -value <0.05, |fold change| ≥2) and canonical pathways (IPA, -value <0.05) associated with organism death and neurological/immune dysfunctions, indicating the conservation of key events related to OPP toxicity. Together, these results build confidence in using short-term, molecular-based assays for the characterization of chemical toxicity and risk, thereby reducing reliance on chronic animal studies.
PubMed: 37888672
DOI: 10.3390/toxics11100820 -
International Journal of Analytical... 2023Antibiotics and pesticides are widespread in most rivers and lakes due to the overuse of antibiotics and pesticides, but there are few methods for simultaneous analysis...
Antibiotics and pesticides are widespread in most rivers and lakes due to the overuse of antibiotics and pesticides, but there are few methods for simultaneous analysis of antibiotics and pesticides in aquatic environments. To address this knowledge gap, a concise and sensitive analytical method is proposed in which three classes of human and veterinary drugs (sulfonamides, macrolides, and hormones) and two classes of pesticides (organophosphorus and neonicotinoids) are simultaneously extracted and determined in surface water. The solid-phase extraction column with Cleanert PEP-2 was preconditioned sequentially with 6 mL of methanol, ultrapure water, and citric acid buffer (pH 3.0) each for simultaneous extraction and further purification. The forty-seven target analytes were analysed by LC-MS/MS in positive and negative ion modes. The LC separation was performed using a Sigma-Aldrich C column with 0.1% formic acid in water and acetonitrile as a gradient eluting mobile phase in positive ion mode. The internal standard method was used to overcome the inevitable matrix effects in LC-MS/MS analysis. The matrix effects of most target analytes were in the range of 27-151%. The recoveries of forty analytes in the three concentrations (10, 50, and 100 ng L) of surface water spiked samples ranged from 41 to 127%. The method quantitative limits of the analytes were in the range of 0.40-5.49 ng L. Application of the method to analyze samples in the eight runoff outlets of the Pearl River Delta showed that some antibiotics and pesticides were detected, and the concentration of parathion was as high as 154 ng L. A powerful tool for quickly and efficiently screening for contaminants in surface water has been presented.
PubMed: 37877028
DOI: 10.1155/2023/6350669