-
Akusherstvo I Ginekologiia 1989Single-hormone prophylaxis with gestagen (Primolut nor) was carried out on 62 women with uterine bleedings during the premenopause of climacteric at mean age of 46.8...
Single-hormone prophylaxis with gestagen (Primolut nor) was carried out on 62 women with uterine bleedings during the premenopause of climacteric at mean age of 46.8 years. A ten-day scheme with application of 5 mg of gestagen daily from 16 to 25 day of the cycle for a period of 6 months was used. The treatment provided stable clinical characteristic of the successive pseudomenstrual cycles could continue for a considerable time practically till disappearance of pseudo-menstruation and transition of the woman in postmenopause. Primolut nor was a convenient drug also in women under continuous anticoagulant treatment. However it was effective and could not be used for treatment of accompanied climacteric symptoms.
Topics: Climacteric; Drug Evaluation; Female; Humans; Menopause; Menopause, Premature; Menstrual Cycle; Middle Aged; Norethindrone; Norsteroids; Uterine Hemorrhage
PubMed: 2764256
DOI: No ID Found -
Ceskoslovenska Gynekologie Apr 1987
Topics: Adult; Contraceptives, Oral, Combined; Female; Humans; Middle Aged; Progesterone Congeners
PubMed: 3594595
DOI: No ID Found -
International Journal of Fertility 1977The LH FSH estradiol and progesterone responses to acute stimulation with LH-RH were studied in 12 normal women with ovulatory cycles (4 in the initial follicular phase,...
The LH FSH estradiol and progesterone responses to acute stimulation with LH-RH were studied in 12 normal women with ovulatory cycles (4 in the initial follicular phase, 4 in the mid-follicular phase and 4 in the late follicular phase) and in two castrated women, two under hormonal contraception, two with ovarian amenorrhea, twelve with central amenorrhea of no detectable origin (6 with normal and 6 with low basal gonadotrophins), eleven anovulatory patients with pseudomenstruation, two with anorexia nervosa, and two with pituitary amenorrhea. Each woman received a rapid i.v. injection of 100 microgram synthetic LH-RH at 9:00 a.m. Serum levels of LH, FSH, estradiol and progesterone were determined by radioimmunoassay in samples collected before and 60, 120, 240 and 480 minutes after injection. The findings were : 1) A significant rise in estradiol and progesterone levels, in addition to LH and FSH elevation, in normal women; 2) A lack of ovarian steroid response in the castrated women and in ovarian amenorrheas, which suggests that the source of steroid response to stimulation is not extragonadal; 3) Significant differences in the responses of the four hormones to LH-RH in the women with central amenorrhea in comparison with the normal group with great variability of results; the steroid response in the presence of a positive LH response might correlate with the severity and/or prognosis of the disorder, a point deserving further study; 4) In anovulatory women with pseudomenstruation, LH responses for the most part normal, and particularly, progesterone responses.
Topics: Adult; Amenorrhea; Anovulation; Castration; Contraceptives, Oral; Estradiol; Female; Follicle Stimulating Hormone; Gonadotropin-Releasing Hormone; Humans; Luteinizing Hormone; Ovary; Ovulation; Pituitary Gland; Pituitary Gland, Anterior; Progesterone
PubMed: 18416
DOI: No ID Found -
Obstetrics and Gynecology Dec 1954
Topics: Endometriosis; Female; Humans; Menstruation; Uterus; Vaginal Neoplasms
PubMed: 13214677
DOI: No ID Found -
Przeglad Lekarski 1953
Topics: Female; Humans; Menstruation
PubMed: 13145698
DOI: No ID Found