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Frontiers in Neurology 2024Drawing on the principles of wrist-ankle acupuncture (WAA), our research team has developed a portable device for WAA point compression, termed the acupressure...
BACKGROUND
Drawing on the principles of wrist-ankle acupuncture (WAA), our research team has developed a portable device for WAA point compression, termed the acupressure wrist-ankle strap (AWA). The current study aims to evaluate the efficacy of the AWA in alleviating pain associated with primary dysmenorrhea.
METHODS
A single-blind, randomized clinical trial was conducted from April 1, 2019, to December 31, 2019. 78 participants with primary dysmenorrhea were recruited from Shanghai University of Traditional Chinese Medicine. All participants were treated on the first day of menstruation for 30 min. Participants in the AWA group used the AWA, the internal side of which is equipped with a tip compression component, while participants in the non-acupressure wrist-ankle acupuncture(NAWA)group used the NAWA, with the inside tip pressing parts removed. The main outcome was the difference in visual analogue scale (VAS) score between baseline and 30 minutes after randomization.
RESULTS
A total of 78 participants aged 18 to 30 years were included in the intention-to-treat analyses. The VAS scores (mean [standard deviation]) in the AWA group were significantly lower than those in the NAWA group at each time point of intervention (5 minutes: 95% CI, [-1.27 to -0.68], < 0.001; 10 minutes: 95% CI, [-2.34 to -1.51], < 0.001; 30 minutes: 95% CI, [-3.74 to -2.72], < 0.001). In the AWA group, 16 participants reported "obvious relief" of dysmenorrhea pain while 23 did not; the average onset time of analgesia they reported were (21.50 ± 3.65) min, while no subjects in NAWA group reported obvious pain relief. The pain threshold (mean [standard deviation]) at SP9 of both sides in AWA group decreased significantly after intervention that in NAWA group (Left: 95% CI, [-5.02 to -1.81], < 0.001; Right: 95% CI, [-7.67 to -4.24], < 0.001). There was no significant change in the temperature at CV4 in either group (95% CI, [-0.63 to -0.66], = 0.970).
CONCLUSION
This trial substantiates our hypothesis that the AWA provides immediate analgesic effects. The AWA represents an effective and safe non-invasive physical therapy option, which patients can self-administer to alleviate abdominal pain.
PubMed: 38872824
DOI: 10.3389/fneur.2024.1362586 -
Integrative Cancer Therapies 2024Among leukemia patients, sleep disruptions are prevalent and can profoundly affect their overall quality of life. Acupressure and foot reflexology, modalities rooted in... (Randomized Controlled Trial)
Randomized Controlled Trial Comparative Study
BACKGROUND
Among leukemia patients, sleep disruptions are prevalent and can profoundly affect their overall quality of life. Acupressure and foot reflexology, modalities rooted in traditional Chinese medicine, have garnered attention for their potential to address sleep disturbances and mitigate associated symptoms.
METHODS
This research utilized a randomized controlled trial with a pretest-posttest design involving 102 leukemia patients admitted to Imam Khomeini Hospital in Urmia. Participants were randomly allocated to 3 groups: acupressure (n = 34), reflexology (n = 34), or control (n = 34). Prior to the intervention, patients completed a demographic survey and the Pittsburgh Sleep Quality Index (PSQI) for baseline assessments. Acupressure involved stimulation of the SP6 point twice daily for 10 minutes over 4 weeks, while reflexology entailed daily 10-minute sessions with sweet almond oil on the soles for the same duration. The control group received standard care without additional interventions. Following the 4-week intervention period, post-intervention evaluations were conducted using identical measurement tools.
RESULTS
The findings underscored the efficacy of both acupressure and foot reflexology in significantly improving sleep quality within the intervention groups ( < .001). Initially, there were no notable differences in sleep quality among the 3 groups ( > .05). Subsequently, pairwise comparisons adjusted with Bonferroni corrections revealed significant disparities in sleep quality between the acupressure and reflexology groups compared to the control group ( < .001). However, post-intervention analysis indicated no statistically significant variance in enhancing sleep quality between the acupressure and foot reflexology groups ( < .05).
CONCLUSION
This study demonstrates that acupressure and foot reflexology interventions can enhance sleep quality in individuals with leukemia. These findings support the effectiveness of these complementary modalities, offering targeted relief and relaxation. While these non-invasive therapies show promise in improving well-being, further research is needed to confirm and expand upon these results due to study limitations.
Topics: Humans; Acupressure; Male; Female; Middle Aged; Adult; Quality of Life; Sleep Quality; Foot; Leukemia; Massage; Sleep Wake Disorders; Medicine, Chinese Traditional; Treatment Outcome
PubMed: 38872330
DOI: 10.1177/15347354241261356 -
Complementary Therapies in Medicine May 2024Given the high prevalence of depression in elderly people, appropriate interventions are essential. This study aimed to assess the effects of auriculotherapy on...
BACKGROUND
Given the high prevalence of depression in elderly people, appropriate interventions are essential. This study aimed to assess the effects of auriculotherapy on depression among elderly people.
METHODS
This randomized controlled clinical trial was conducted in 2021. Fifty-two elderly were conveniently selected and randomly allocated to the sham (n = 26) and intervention (n = 26) groups through block randomization. The intervention group was subjected to four weeks of auriculotherapy at the Shen-Men, zero, heart, antidepressant, and master cerebral points using Vaccaria seeds fixed with adhesive tape. In the sham group, adhesive tapes were attached to the points with neither seeds nor compression. The elderly and data collector were blinded. The 15-item Geriatric Depression Scale was used to assess depression before, immediately after, and four weeks after the intervention (T1-T3). The statistical methods used were repeated measures analysis of variance and covariance.
RESULTS
Groups significantly differed concerning participants' gender, education, and employment (p < 0.05). After adjusting for confounding effects, the time-group interaction significantly affected the mean depression score (p < 0.0001, effect size = 0.54). There was no significant difference between the depression score in the sham and intervention groups at T1 (9.6 ± 2.5 vs 9.5 ± 2.5, p = 0.263); however, this difference was found to be significant at T2 (8.6 ± 2 vs 4.2 ± 1.2, p < 0.0001, effect size = 0.68) and T3 (9.3 ± 2.3 vs 4.3 ± 1.3, p < 0.0001, effect size = 0.65). Within-group analysis revealed significant differences in the depression scores of the intervention group at T1 compared with those at T2 and T3 (p < 0.05). In contrast, the mean depression score in the sham group at T2 was significantly lower than that at T1 (p = 0.003) and greater than that at T3 (p = 0.049).
CONCLUSIONS
Auriculotherapy alleviates depression and can be used as a complementary therapy for elderly people with depression.
PubMed: 38789059
DOI: 10.1016/j.ctim.2024.103054 -
Healthcare (Basel, Switzerland) May 2024The existing literature has limited detail on theory-driven interventions, particularly in pain studies. We adapted Bandura's self-efficacy framework toward a...
BACKGROUND
The existing literature has limited detail on theory-driven interventions, particularly in pain studies. We adapted Bandura's self-efficacy framework toward a theory-driven, non-pharmacological intervention using auricular point acupressure (APA) and evaluated participants' perceptions of this intervention on their pain self-management. APA is a non-invasive modality based on auricular acupuncture principles.
METHODS
We mapped our study intervention components according to Bandura's key sources of self-efficacy (performance accomplishments, vicarious experience, verbal persuasion, and emotional arousal) to facilitate the self-management of pain. Through a qualitative study design, we conducted virtual interviews at one and three months after a 4-week APA intervention among 23 participants using purposive sampling to describe their experiences in managing their pain based on our theory-driven APA intervention.
RESULTS
Using thematic analyses, we found four themes: the enhanced self-management of pain, improved pain outcomes, the feasibility of technology, and the sustainability of APA.
CONCLUSIONS
Describing how interventions are mapped according to the elements of theoretical frameworks can help to guide intervention development, advance science and knowledge development, and promote the implementation of interventions. As such, using Bandura's self-efficacy theory as a foundation for the APA intervention, APA was found to be feasible and sustainable, improving self-management, pain intensity, and pain-related outcomes. Participants provided recommendations for the further improvement of this theory-driven intervention.
PubMed: 38786380
DOI: 10.3390/healthcare12100969 -
Frontiers in Neurology 2024Migraine is a prevalent and disabling neurovascular disorder, with women being more susceptible, characterized by unilateral throbbing headache, often accompanied by... (Review)
Review
Migraine is a prevalent and disabling neurovascular disorder, with women being more susceptible, characterized by unilateral throbbing headache, often accompanied by nausea and vomiting, and often associated with various comorbidities such as brain and cardiovascular diseases, which can have a serious impact on quality of life. Although nonsteroidal anti-inflammatory drugs (NSAIDs) are the main first-line medications for the treatment of pain, long-term use often leads to side effects and drug addiction, which emphasizes the need to investigate alternative pain management strategies with fewer adverse effects. Complementary and alternative medicine is a viable pain intervention often used in conjunction with traditional medications, including acupuncture, herbs, moxibustion, transcutaneous electrical stimulation, bio-supplements, and acupressure, which offer non-pharmacological alternatives that are now viable pain management options. This review focuses on the mechanistic doctrine of migraine generation and the role and potential mechanisms of Complementary and Alternative Therapies (CAT) in the treatment of migraine, summarizes the research evidences for CAT as an adjunct or alternative to conventional therapies for migraine, and focuses on the potential of novel migraine therapies (calcitonin gene-related peptide (CGRP) antagonists and pituitary adenylyl cyclase-activating peptide (PACAP) antagonists) with the aim of evaluating CAT therapies as adjunctive or alternative therapies to conventional migraine treatment, thereby providing a broader perspective on migraine management and the design of treatment programs for more effective pain management.
PubMed: 38784897
DOI: 10.3389/fneur.2024.1372509 -
Frontiers in Medicine 2024The use of Complementary and Integrative Medicine (CIM) is very popular among the general population in Germany. However, international studies show that nurses,...
INTRODUCTION
The use of Complementary and Integrative Medicine (CIM) is very popular among the general population in Germany. However, international studies show that nurses, physicians, and other health care professionals (HCPs) at hospitals often do not feel sufficiently informed about different CIM approaches. Moreover, they do not feel trained enough to counsel their patients appropriately. In the German-speaking context, particularly within university hospitals, research on this subject is scarce. Therefore, the aim of this explorative study was to evaluate attitudes, subjective knowledge, and needs regarding CIM among HCPs with direct patient interaction across all four university hospitals in the federal state of Baden-Württemberg, Germany (Tübingen, Ulm, Freiburg, Heidelberg).
METHODS
The multicenter, cross-sectional, anonymous full survey was conducted online using a self-developed, semi-structured, web-based questionnaire. Recruitment took place via all-inclusive e-mail distribution lists of all four university hospitals.
RESULTS
A total of = 2,026 participants (response rate varied by location from about 5 to 14%) fully answered the questionnaire. Nurses constituted the largest professional group ( = 1,196; 59%), followed by physicians ( = 567; 28%), physiotherapists ( = 54), psychologists ( = 48), midwives ( = 37), and other professions ( = 124). More than two-thirds (71%, = 1,437) of the participants were female and 14% ( = 286) reported additional training in CIM. The overall attitude toward CIM (10-point Likert scale, 10 = "very favorable") was clearly positive ( ± : 7.43 ± 2.33), with notable differences between professional groups: midwives (9.05 ± 1.18), physiotherapists (8.44 ± 1.74), and nurses (8.08 ± 1.95) expressed the highest support, whereas physicians (5.80 ± 2.39) the lowest. 42% of the participants incorporated CIM in patient care (from 33% of physicians to 86% of midwives). Overall, relaxation therapy ( = 1,951; 96%), external applications ( = 1,911; 94%), massage ( = 1,836; 91%), and meditation/mindfulness ( = 1,812; 89%) were rated as useful or rather useful for patients. The average self-assessed knowledge level about CIM was moderate (M ± SD: 5.83 ± 2.03). Most of the participants found CIM training at university hospitals important and saw research about CIM as one of the tasks of university hospitals. The participants expressed the highest interest in education for acupuncture/acupressure, relaxation therapies, and manual medicine.
DISCUSSION
This comprehensive survey of health care professionals (HCPs) at university hospitals in Germany reveals a clearly positive disposition toward CIM, aligning with findings from other hospital-based surveys and highlighting differences among professional groups. While most therapies deemed beneficial for patient care are supported by positive evidence, further research is required for others. Given the average self-reported knowledge of CIM, targeted education is essential to meet the needs of both HCPs and patients and to ensure the provision of evidence-based information on the risks and benefits of CIM.
PubMed: 38784234
DOI: 10.3389/fmed.2024.1408653 -
Clinical Parkinsonism & Related... 2024Freezing of gait (FOG) involves dysfunction of the motor and sensory systems. Peripheral sensory stimuli, including Thai acupressure, can improve proprioceptive function...
INTRODUCTION
Freezing of gait (FOG) involves dysfunction of the motor and sensory systems. Peripheral sensory stimuli, including Thai acupressure, can improve proprioceptive function and decrease FOG episodes. Here, we sought to determine the efficacy of acupressure as a self-treatment to alleviate FOG in patients with Parkinson's disease (PD).
METHODS
We conducted an open-label, controlled trial of 60 PD patients with FOG while medicated, randomised into two groups: an active-treatment group using silicone pads to apply pressure to plantar acupoints on the head of the big toe and the base of the first metatarsal bone on each foot for 6 s using patient body weight while seated, repeated four times for each acupoint bilaterally, and a sham-treatment group using a similar protocol without the silicone pads. The primary outcome was stride length. Secondary outcomes included FOG episodes, FOG duration, percent duration of FOG to total gait time (%FOG), and gait parameters. A baseline-adjusted analysis of covariance was used to compare outcomes between the two groups.
RESULTS
Compared with the sham treatment, the active treatment increased stride length, gait velocity, and cadence (all < 0.001), and decreased FOG episodes and duration (both < 0.001), %FOG ( = 0.011), and double-support time ( < 0.001). No adverse effects were noted.
CONCLUSIONS
Acupressure using silicone pads to stimulate plantar acupoints for self-treatment is a noninvasive, simple, safe way to improve gait and alleviate FOG in patients with PD.
CLINICAL TRIAL REGISTRATION
We registered the study prospectively in the Thai Clinical Trial Registry No. TCTR20200317001.
PubMed: 38778886
DOI: 10.1016/j.prdoa.2024.100254 -
JMIR Research Protocols May 2024Curcuminoids and acupressure have beneficial effects in reducing pain and inflammation in patients with Osteoarthritis. However, only a few clinical trials are...
BACKGROUND
Curcuminoids and acupressure have beneficial effects in reducing pain and inflammation in patients with Osteoarthritis. However, only a few clinical trials are investigating biomarkers to prove this objectively.
OBJECTIVE
This study aimed to investigate the efficacy of acupressure and curcuminoids to inflammatory markers and pain in elderly with Osteoarthritis Genu.
METHODS
Randomized controlled trial (RCT) was conducted among elderly with Osteoarthritis. All participants were randomized to divided into the group with 30 mg curcuminoids from turmeric extract capsules and acupressure (group 1) or the group with placebo and sham acupressure (group 2) for 3 weeks.
RESULTS
The study was approved by the research ethics board and Clinical Trials.gov had reviewed this protocol. The extracts were manufactured from May 2023 to June 2023. Participant recruitment was conducted in September-October 2023, a total of 72 participants aged over 60 years had participated of whom 75.0% (n=54) were female. Data was analyzed in April of 2024, and dissemination of results by the end of 2024.
CONCLUSIONS
Primary outcomes were assessed at baseline and after intervention and related to inflammatory markers, endorphin hormones, and cycloxygenase-2 hormone in the blood. Additionally, secondary outcomes included pain, ability to activity daily living, and quality of life. The beneficial effects that may be found in this trial can be exceptionally relevant in clinical practice, justifying this scientific question. The benefits of herbs and acupressure can be helpful to additional options in treating inflammation and pain in patients with Osteoarthritis.
CLINICALTRIAL
ClinicalTrials.gov NCT06105840 (https://classic.clinicaltrials.gov/ct2/show/NCT06105840).
PubMed: 38771152
DOI: 10.2196/54970 -
Medicine May 2024The effectiveness of different medical interventions in managing labor pain has yielded mixed results. Therefore, this systematic review and network meta-analysis aimed... (Meta-Analysis)
Meta-Analysis
BACKGROUND
The effectiveness of different medical interventions in managing labor pain has yielded mixed results. Therefore, this systematic review and network meta-analysis aimed to provide a comprehensive summary of the available evidence on the impact of different strategies for reducing labor pain.
METHODS
We systematically searched 3 English databases (Pubmed, Embase and the Cochrane Library) from inception to January 2023. Randomized controlled trials (RCTs) or controlled clinical trials that investigating the effects of different strategies for reducing labor pain were included in this network meta-analysis. Risk of bias (ROB) was assessed using the Cochrane ROB tools. Network meta-analysis was performed using the R software (version 4.2.1) with gemtc package.
RESULTS
A total of 9 studies involving 823 patients, including 9 treatments (acupressure, birth ball exercise, Bonapace method, distraction techniques, ice pressure, LI4 acupressure, lidocaine spray, smartphone-based music intervention and placebo). The surface under the cumulative ranking (SUCRA) shows that Bonapace method ranked first (SUCRA, 79.5%), LI4 acupressure ranked second (SUCRA, 65.6%), distraction technique ranked third (SUCRA, 57.6%), birth ball exercise ranked fourth (SUCRA, 51.8%).
CONCLUSIONS
According to the results of the network meta-analysis, among the different strategies examined, the Bonapace Method stands out as the most effective nonpharmacological intervention for reducing labor pain. The results of this meta-analysis can aid both patients and healthcare professionals in choosing the most effective techniques to reduce labor pain.
Topics: Humans; Bayes Theorem; Female; Pregnancy; Labor Pain; Randomized Controlled Trials as Topic; Network Meta-Analysis; Pain Management; Acupressure
PubMed: 38758902
DOI: 10.1097/MD.0000000000037594