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Qualitative Social Work : QSW :... Mar 2021My emotional responses to this moment include feelings of anger, hope, and déjà vu. Although the scope and scale of this pandemic is unprecedented in our lifetimes,...
My emotional responses to this moment include feelings of anger, hope, and déjà vu. Although the scope and scale of this pandemic is unprecedented in our lifetimes, what has been especially hard is not necessarily new - nor entirely unprecedented - and therefore unavoidable. In this essay, I reflect on what was avoidable and call for better response. We must question the seemingly benign (if not optimistic) terms emerging as pandemic discourse, such as "pivot to a new normal" and "essential work," for what they reveal of social injustice and failure to avert future crisis.
PubMed: 34253964
DOI: 10.1177/1473325020973394 -
Canadian Journal of Psychiatry. Revue... Jan 2022
Topics: Health Policy; Humans; Illicit Drugs; Substance-Related Disorders
PubMed: 34036818
DOI: 10.1177/07067437211019656 -
Annals of Internal Medicine Jun 2021
Topics: Community Participation; Firearms; Humans; Mass Casualty Incidents; Physician's Role; United States; Wounds, Gunshot
PubMed: 33793324
DOI: 10.7326/M21-1505 -
Perspectives on Psychological Science :... Jan 2022Psychological science is increasingly influencing public policy. Behavioral public policy (BPP) was a milestone in this regard because it influenced many areas of policy...
Psychological science is increasingly influencing public policy. Behavioral public policy (BPP) was a milestone in this regard because it influenced many areas of policy in a general way. Well-being public policy (WPP) is emerging as a second domain of psychological science with general applicability. However, advocacy for WPP is criticized on ethical and political grounds. These criticisms are reminiscent of those directed at BPP over the past decade. This déjà vu suggests the need for interdisciplinary work that establishes normative principles for applying psychological science in public policy. We try to distill such principles for WPP from the normative debates over BPP. We argue that the uptake of BPP by governments was a function of its relatively strong normative and epistemic foundations in libertarian paternalism, or , for short. We explain why the nudge framework is inappropriate for WPP. We then analyze how offer a strict but feasible alternative framework for substantiating the legitimacy of well-being and behavioral policies. We illuminate how some WPPs could be fruitfully promoted as boosts and how they might fall short of the associated criteria.
Topics: Choice Behavior; Humans; Paternalism; Public Policy
PubMed: 33682526
DOI: 10.1177/1745691620984395 -
The British Journal of General Practice... 2021
Topics: Health Status Disparities; Humans
PubMed: 33632678
DOI: 10.3399/bjgp21X714941 -
Annals of Internal Medicine Jun 2021Klompas and colleagues report an investigation of a SARS-CoV-2 cluster in an acute care hospital with transmission between patients and staff. The editorialists remind...
Klompas and colleagues report an investigation of a SARS-CoV-2 cluster in an acute care hospital with transmission between patients and staff. The editorialists remind us of the need to reinforce and reeducate to improve practice of and adherence to important strategies that protect the entire health care ecosystem.
Topics: COVID-19; Delivery of Health Care; Hospitals; Humans; SARS-CoV-2
PubMed: 33556269
DOI: 10.7326/M21-0526 -
Environmental Science and Pollution... Apr 2021The pandemic of coronavirus disease 2019 (COVID-19), caused by the novel coronavirus SARS-CoV-2, is generating a high number of deaths worldwide. One of the current...
Effects of the spread of COVID-19 on public health of polluted cities: results of the first wave for explaining the dejà vu in the second wave of COVID-19 pandemic and epidemics of future vital agents.
The pandemic of coronavirus disease 2019 (COVID-19), caused by the novel coronavirus SARS-CoV-2, is generating a high number of deaths worldwide. One of the current questions in the field of environmental science is to explain how air pollution can affect the impact of COVID-19 pandemic on public health. The research here focuses on a case study of Italy. Results suggest that the diffusion of COVID-19 in cities with high levels of air pollution is generating higher numbers of COVID-19 related infected individuals and deaths. In particular, results reveal that the number of infected people was higher in cities with more than 100 days per year exceeding limits set for PM or ozone, cities located in hinterland zones (i.e. away from the coast), cities having a low average speed of wind and cities with a lower average temperature. In hinterland cities having a high level of air pollution, coupled with low wind speed, the average number of infected people in April 2020-during the first wave of the COVID-19 pandemic-is more than tripled compared to cities with low levels of air pollution. In addition, results show that more than 75% of infected individuals and about 81% of deaths of the first wave of COVID-19 pandemic in Italy are in industrialized regions with high levels of air pollution. Although these vital results of the first wave of the COVID-19 from February to August 2020, policymakers have had a low organizational capacity to plan effective policy responses for crisis management to cope with COVID-19 pandemic that is generating recurring waves with again negative effects, déjà vu, on public health and of course economic systems.
Topics: Air Pollutants; Air Pollution; COVID-19; Cities; Humans; Italy; Pandemics; Particulate Matter; Public Health; SARS-CoV-2
PubMed: 33398753
DOI: 10.1007/s11356-020-11662-7 -
Epilepsy & Behavior : E&B Feb 2021Descriptions of seizure manifestations (SM), or semiology, can help localize the symptomatogenic zone and subsequently included brain regions involved in epileptic...
PURPOSE
Descriptions of seizure manifestations (SM), or semiology, can help localize the symptomatogenic zone and subsequently included brain regions involved in epileptic seizures, as well as identify patients with dissociative seizures (DS). Patients and witnesses are not trained observers, so these descriptions may vary from expert review of seizure video recordings of seizures. To better understand how reported factors can help identify patients with DS or epileptic seizures (ES), we evaluated the associations between more than 30 SMs and diagnosis using standardized interviews.
METHODS
Based on patient- and observer-reported data from 490 patients with diagnoses documented by video-electoencephalography, we compared the rate of each SM in five mutually exclusive groups: epileptic seizures (ES), DS, physiologic seizure-like events (PSLE), mixed DS and ES, and inconclusive testing.
RESULTS
In addition to SMs that we described in a prior manuscript, the following were associated with DS: light triggers, emotional stress trigger, pre-ictal and post-ictal headache, post-ictal muscle soreness, and ictal sensory symptoms. The following were associated with ES: triggered by missing medication, aura of déjà vu, and leftward eye deviation. There were numerous manifestations separately associated with mixed ES and DS.
CONCLUSIONS
Reported SM can help identify patients with DS, but no manifestation is pathognomonic for either ES or DS. Patients with mixed ES and DS reported factors divergent from both ES-alone and DS-alone.
Topics: Conversion Disorder; Electroencephalography; Humans; Reproducibility of Results; Retrospective Studies; Seizures
PubMed: 33388672
DOI: 10.1016/j.yebeh.2020.107696 -
EuroIntervention : Journal of EuroPCR... Oct 2020
Topics: Brain; Electroencephalography; Emotions; Humans
PubMed: 33095165
DOI: 10.4244/EIJV16I8A116 -
Blood Nov 2020Activated B-cell (ABC)-diffuse large B-cell lymphomas (DLBCLs) are clinically aggressive and phenotypically complex malignancies, whose transformation mechanisms remain...
Activated B-cell (ABC)-diffuse large B-cell lymphomas (DLBCLs) are clinically aggressive and phenotypically complex malignancies, whose transformation mechanisms remain unclear. Partially differentiated antigen-secreting cells (plasmablasts) have long been regarded as cells-of-origin for these tumors, despite lack of definitive experimental evidence. Recent DLBCL reclassification based on mutational landscapes identified MCD/C5 tumors as specific ABC-DLBCLs with unfavorable clinical outcome, activating mutations in the signaling adaptors MYD88 and CD79B, and immune evasion through mutation of antigen-presenting genes. MCD/C5s manifest prominent extranodal dissemination and similarities with primary extranodal lymphomas (PENLs). In this regard, recent studies on TBL1XR1, a gene recurrently mutated in MCD/C5s and PENLs, suggest that aberrant memory B cells (MBs), and not plasmablasts, are the true cells-of-origin for these tumors. Moreover, transcriptional and phenotypic profiling suggests that MCD/C5s, as a class, represent bona fide MB tumors. Based on emerging findings we propose herein a generalized stepwise model for MCD/C5 and PENLs pathogenesis, whereby acquisition of founder mutations in activated B cells favors the development of aberrant MBs prone to avoid plasmacytic differentiation on recall and undergo systemic dissemination. Cyclic reactivation of these MBs through persistent antigen exposure favors their clonal expansion and accumulation of mutations, which further facilitate their activation. As a result, MB-like clonal precursors become trapped in an oscillatory state of semipermanent activation and phenotypic sway that facilitates ulterior transformation and accounts for the extranodal clinical presentation and biology of these tumors. In addition, we discuss diagnostic and therapeutic implications of a MB cell-of-origin for these lymphomas.
Topics: B-Lymphocytes; Humans; Immunologic Memory; Lymphoma, Large B-Cell, Diffuse
PubMed: 32932517
DOI: 10.1182/blood.2020005857