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Optics Express Apr 2024Orthogonal frequency-division multiplexing (OFDM) waveform is highly preferred as a dual-function candidate for integrated sensing and communication (ISAC) systems....
Orthogonal frequency-division multiplexing (OFDM) waveform is highly preferred as a dual-function candidate for integrated sensing and communication (ISAC) systems. However, the sensitivity to both carrier frequency offset (CFO) and phase noise greatly impedes its applications in millimeter-wave ISAC systems. Here, we propose and experimentally demonstrate a photonic millimeter-wave ISAC system employing the virtual-carrier-aided self-coherent OFDM technique, wherein a digitally-generated local oscillator is transmitted along with the OFDM signal. Then, a compact CFO-immune and phase noise-immune envelope detection method is implemented for down-converting millimeter-wave communication and radar echo signals. In experiments, a V-band ISAC system is successfully implemented with a simplified remote radio unit, using the remote photonic millimeter-wave heterodyning up-conversion for downlink and the envelope detection-assisted down-conversion for uplink (or radar echoes). In the converged transmission link with a 5-km fiber link and 2-m space link, the Kramers-Kronig (KK) receiver supports a communication data rate up to 16-Gbit/s by mitigating signal-signal beat interference (SSBI). More significantly, the SSBI leads to negligible effects on the sensing performance when classic matched filtering is adopted for target identification. Consequently, a 4.8-cm range resolution and a 4-mm range accuracy are obtained for the radar sensing function.
PubMed: 38859198
DOI: 10.1364/OE.513686 -
Optics Express May 2024In order to guarantee the information of the W-band wireless communication system from the physical layer, this paper proposes the sliced chaotic encrypted (SCE)...
In order to guarantee the information of the W-band wireless communication system from the physical layer, this paper proposes the sliced chaotic encrypted (SCE) transmission scheme based on key masked distribution (KMD). The scheme improves the security of free space communication in the W-band millimeter-wave wireless data transmission system. In this scheme, the key information is embedded into the random position of the ciphertext information, and then the ciphertext carrying the key information is encrypted by multi-dimensional chaos. Chaotic system 1 constructs a three-dimensional discrete chaotic map for implementing KMD. Chaotic system 2 constructs complex nonlinear dynamic behavior through the coupling of two neurons, and the masking factor generated is used to realize SCE. In this paper, the transmission of 16QAM signals in a 4.5 m W-band millimeter-wave wireless communication system with a rate of 40 Gb/s is proved by experiments, and the performance of the system is analyzed. When the input optical power is 5 dBm, the bit error rate (BER) of the legitimate encrypted receiver is 1.23 × 10. When the offset of chaotic sequence x and chaotic sequence y is 100, their BERs are more than 0.21. The key space of the chaotic system reaches 10, which can effectively prevent illegal attacks and improve the security performance of the system. The experimental results show that the scheme can effectively distribute the keys and improve the security of the system. It has great application potential in the future of W-band millimeter-wave wireless secure communication.
PubMed: 38859046
DOI: 10.1364/OE.524790 -
Optics Express May 2024A Fe-InP-based planar array antenna-coupled InGaAs/InAlAs multiple quantum well (MQW) optical phase modulator is proposed and demonstrated for radio over fiber (RoF)...
A Fe-InP-based planar array antenna-coupled InGaAs/InAlAs multiple quantum well (MQW) optical phase modulator is proposed and demonstrated for radio over fiber (RoF) applications with 60 GHz-band millimeter-wave wireless signals. The modulator comprises five types of five-layer asymmetric coupled quantum wells (FACQWs) and a two-element array antenna. The FACQWs are designed to have a significant electric-field-induced refractive index change with small electric fields induced in the antenna. In the fabricated modulator, a carrier-to-sideband ratio (CSR) of up to 45.9 dB was successfully obtained at a power density of 11 W/m, corresponding to a phase shift of 10.1 mrad. Furthermore, data transmission of a 2 GHz modulated wave with a 60 GHz wireless carrier wave was demonstrated.
PubMed: 38859020
DOI: 10.1364/OE.525299 -
Optics Express May 2024The application of dual vector millimeter-wave (mm-wave) signals in radio-over-fiber (RoF) systems represents a significant opportunity to enhance spectrum efficiency,...
The application of dual vector millimeter-wave (mm-wave) signals in radio-over-fiber (RoF) systems represents a significant opportunity to enhance spectrum efficiency, transmission capacity, and access flexibility. In addition, facing the increasingly intricate application scenarios, the comprehensive exploitation of high-order quadrature-amplitude-modulation (QAM) signals with hybrid single-carrier (SC) and orthogonal-frequency-division-multiplexing (OFDM) modulation is also vital to rich systematic connotation. Based on bandpass delta-sigma modulation (BP-DSM) and heterodyne detection, we propose what we believe to be a novel scheme for the simultaneous wireless mm-wave transmission of both SC-modulated and OFDM-modulated high-order QAM signals. The innovation lies in the modulation-agnostic nature, accommodating both SC-modulated and OFDM-modulated vector radio-frequency (RF) signals. The BP-DSM is utilized to digitize two independent SC-modulated and OFDM-modulated high-order QAM signals into relatively simple sequences at the transmitter side. With the aid of an optical I/Q modulator, we can integrate both signals after BP-DSM to generate the desired optical quadrature-phase-shift keying (QPSK) signal carrying both information of two original high-order QAM signals. Facilitated by heterodyne detection and a single photodetector (PD), our scheme attains prowess in the detection of both SC-modulated and OFDM-modulated high-order signals. Based on our proposed scheme, we experimentally demonstrate the simultaneous wireless mm-wave transmission of both SC-modulated and OFDM-modulated 512QAM signals at 30-GHz mm-wave band, demonstrating bit-error-rates (BERs) below the hard decision forward error correction (HD-FEC) threshold of 3.8 × 10 after transmission over 10-km single-mode fiber (SMF) link and 1-m wireless link. In addition, we further investigate the performance impact between SC-modulated and OFDM-modulated high-order QAM signals, and experiment results indicate that the impact is virtually negligible. Moreover, the performance of the generated QPSK mm-wave signal is transparent to the QAM modulation formats of both SC-modulated and OFDM-modulated signals in our proposed scheme.
PubMed: 38858936
DOI: 10.1364/OE.521148 -
Optics Express May 2024The independent optical dual-single-sideband (dual-SSB) signal generation and detection can be achieved by an optical in-phase/quadrature (I/Q) modulator and one single...
The independent optical dual-single-sideband (dual-SSB) signal generation and detection can be achieved by an optical in-phase/quadrature (I/Q) modulator and one single photodiode (PD). The dual-SSB signal is able to carry two different information. After PD detection, the optical dual-SSB signal can be converted into an electrical millimeter-wave (mm-wave) signal. Therefore, the optical dual-SSB signal generation and detection technique can be employed in the radio-over-fiber (RoF) system to achieve higher system spectral efficiency and reduce system architecture complexity. However, the I/Q modulator's nonideal property results in the amplitude imbalance of the optical dual-SSB signal, and then the crosstalk can occur. Moreover, after PD detection, the generated mm-wave signal based on the optical dual-SSB modulation has a relatively low signal-to-noise ratio (SNR), which restricts the system performance. In this paper, we propose an optical asymmetrical dual-SSB signal generation and detection scheme based on the probabilistic shaping (PS) technology, to decrease the influence of the optical dual-SSB signal's amplitude imbalance and to enhance the system performance in the scenario of the limited SNR. The dual-SSB in our scheme is composed of the left sideband (LSB) in probabilistic-shaping geometric-shaping 4-ary quadrature amplitude modulation (PS-GS4QAM) format and the right sideband (RSB) in quadrature phase-shift keying (QPSK) format. The transmitter digital signal processing (DSP) generates a dual-SSB signal to drive the optical I/Q modulator. The I/Q modulator implements an electrical-to-optical conversion and generates an optical dual-SSB signal. After PD detection, the optical dual-SSB signal is converted into a PS-16QAM mm-wave signal. In our simulation, compared with the normal 16QAM scenario, the PS-16QAM scenario exhibits a ∼1.2 dB receiver sensitivity improvement at the hard-decision forward error correction (HD-FEC) threshold of 3.8×10. Therefore, in our experiment, based on the PS technology, we design a dual-SSB signal including a 5 Gbaud LSB-PS-GS4QAM at -15 GHz and a 5 Gbaud RSB-QPSK at 20 GHz. After 5 km standard single-mode fiber (SSMF) transmission and PD detection, the dual-SSB signal is converted into a 5 Gbaud PS-16QAM mm-wave signal at 35 GHz. Then, the generated PS-16QAM signal is sent into a 1.2 m single-input-single-output (SISO) wireless link. In the DSP at the receiver end, the dual-SSB signal can be recovered from the mm-wave signal, and the PS-GS4QAM and QPSK data carried by the dual-SSB signal can be separated. The bit error rates (BERs) of the LSB-PS-GS4QAM and the RSB-QPSK in our experiment can be below the HD-FEC threshold of 3.8×10. The results demonstrate that our scheme can tolerate the I/Q modulator's nonideal property and performs well in the scenario of a relatively low SNR.
PubMed: 38858933
DOI: 10.1364/OE.520062 -
Biomedical Optics Express May 2024The attenuation coefficient of biological tissue could serve as an indicator of structural and functional changes related to the onset or progression of disease. Optical...
The attenuation coefficient of biological tissue could serve as an indicator of structural and functional changes related to the onset or progression of disease. Optical coherence tomography (OCT) provides cross sectional images of tissue up to a depth of a few millimeters, based on the local backscatter properties. The OCT intensity also depends on the confocal function, which needs to be characterised to determine correctly the exponential decay of the intensity based on Lambert-Beer. We present a model for the confocal function in scattering media based on the illumination with a Gaussian beam and the power transfer into a single mode fibre (SMF) of the backscattered light for an incoherently back scattered Gaussian beam using the Huygens-Fresnel principle and compare that model with the reflection from a mirror. We find that, contrary to previous literature, the confocal functions characterised by the Rayleigh range in the two models are identical. Extensive OCT focus series measurements on a mirror, Spectralon and Intralipid dilutions confirm our model, and show that for highly scattering samples the confocal function characterised by the Rayleigh range becomes depth dependent. From the diluted Intralipid measurements the attenuation coefficients are extracted using a singly scatter model that includes the previously established confocal function. The extracted attenuation coefficients were in good agreement for weakly scattering samples ( < 2 mm).
PubMed: 38855667
DOI: 10.1364/BOE.516229 -
BioRxiv : the Preprint Server For... May 2024Receptor tyrosine kinases (RTKs) are thought to play key roles in coordinating cell movement at single-cell and tissue scales. The recent development of optogenetic...
Receptor tyrosine kinases (RTKs) are thought to play key roles in coordinating cell movement at single-cell and tissue scales. The recent development of optogenetic tools for controlling RTKs and their downstream signaling pathways suggested these responses may be amenable to engineering-based control for sculpting tissue shape and function. Here, we report that a light-controlled EGF receptor (OptoEGFR) can be deployed in epithelial cell lines for precise, programmable control of long-range tissue movements. We show that in OptoEGFR-expressing tissues, light can drive millimeter-scale cell rearrangements to densify interior regions or produce rapid outgrowth at tissue edges. Light-controlled tissue movements are driven primarily by PI 3-kinase signaling, rather than diffusible signals, tissue contractility, or ERK kinase signaling as seen in other RTK-driven migration contexts. Our study suggests that synthetic, light-controlled RTKs could serve as a powerful platform for controlling cell positions and densities for diverse applications including wound healing and tissue morphogenesis.
PubMed: 38853934
DOI: 10.1101/2024.05.30.596676 -
BioRxiv : the Preprint Server For... May 2024Interacting with the environment to process sensory information, generate perceptions, and shape behavior engages neural networks in brain areas with highly varied...
Interacting with the environment to process sensory information, generate perceptions, and shape behavior engages neural networks in brain areas with highly varied representations, ranging from unimodal sensory cortices to higher-order association areas. Recent work suggests a much greater degree of commonality across areas, with distributed and modular networks present in both sensory and non-sensory areas during early development. However, it is currently unknown whether this initially common modular structure undergoes an equally common developmental trajectory, or whether such a modular functional organization persists in some areas-such as primary visual cortex-but not others. Here we examine the development of network organization across diverse cortical regions in ferrets of both sexes using widefield calcium imaging of spontaneous activity. We find that all regions examined, including both primary sensory cortices (visual, auditory, and somatosensory-V1, A1, and S1, respectively) and higher order association areas (prefrontal and posterior parietal cortices) exhibit a largely similar pattern of changes over an approximately 3 week developmental period spanning eye opening and the transition to predominantly externally-driven sensory activity. We find that both a modular functional organization and millimeter-scale correlated networks remain present across all cortical areas examined. These networks weakened over development in most cortical areas, but strengthened in V1. Overall, the conserved maintenance of modular organization across different cortical areas suggests a common pathway of network refinement, and suggests that a modular organization-known to encode functional representations in visual areas-may be similarly engaged in highly diverse brain areas.
PubMed: 38853883
DOI: 10.1101/2024.05.28.595371 -
Forensic Science International. Genetics May 2024We report on testing 100 individuals for their shedder status with the aim of demonstrating whether the process of cell staining is reproducible when testing a large...
We report on testing 100 individuals for their shedder status with the aim of demonstrating whether the process of cell staining is reproducible when testing a large number of people. A previous report using the same method was based on 11 donors and indicated that there may be a continuum of shedder types within this small sample set. In this report we also expand the time points post-handwashing to 0, 15, 30, 60, and 180 min. Triplicate samples were collected from both the right and left thumbs. Samples were collected by donors placing a thumb on a clean glass slide and then adding a DNA binding dye. The number of cells were recorded within three separate square millimetre areas (cells/mm) at 220x magnification. The experiments were conducted in triplicate on three different days, giving a total of 72 thumbprints per individual. Finally, there were 3438 observed frames in the entire dataset. Of the 100 donors, 98 gave consistent and reproducible cell number deposition. There was no difference between the cells deposited by the left and right thumbs in 13 of 15 tested. Males tended to deposit more cells than females. If applying arbitrary boundary to a cell count to definitively determine shedder status, then many of the donors fell within two categories. This study based on 100 individuals strongly suggests that shedder status is a continuum phenomenon.
PubMed: 38851033
DOI: 10.1016/j.fsigen.2024.103065 -
Communications Physics 2024Optical resonators are indispensable tools in optical metrology that usually benefit from an evacuated and highly-isolated environment to achieve peak performance. Even...
Optical resonators are indispensable tools in optical metrology that usually benefit from an evacuated and highly-isolated environment to achieve peak performance. Even in the more sophisticated design of Fabry-Perot (FP) cavities, the material choice limits the achievable quality factors. For this reason, monolithic resonators are emerging as promising alternative to traditional designs, but their design is still at preliminary stage and far from being optimized. Here, we demonstrate a monolithic FP resonator with 4.5 cm volume and 2 × 10 finesse. In the ambient environment, we achieve 18 Hz integrated laser linewidth and 7 × 10 frequency stability measured from 0.08 s to 0.3 s averaging time, the highest spectral purity and stability demonstrated to date in the context of monolithic reference resonators. By locking two separate lasers to distinct modes of the same resonator, a 96 GHz microwave signals is generated with phase noise -100 dBc/Hz at 10 kHz frequency offset, achieving orders of magnitude improvement in the approach of photonic heterodyne synthesis. The compact monolithic FP resonator is promising for applications in spectrally-pure, high-frequency microwave photonic references as well as optical clocks and other metrological devices. ©2024. All rights reserved.
PubMed: 38845615
DOI: 10.1038/s42005-024-01660-3