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Sensors (Basel, Switzerland) May 2024Radon is a naturally occurring noble radioactive gas that poses significant health risks, particularly lung cancer, due to its colorless, odorless, and tasteless nature,... (Review)
Review
Radon is a naturally occurring noble radioactive gas that poses significant health risks, particularly lung cancer, due to its colorless, odorless, and tasteless nature, which makes detection challenging without formal testing. It is found in soil, rock, and water, and it infiltrates indoor environments, necessitating regulatory standards and guidelines from organizations such as the Environmental Protection Agency, the World Health Organization, and the Occupational Health and Safety Agency to mitigate exposure. In this paper, we present various methods and instruments for radon assessment in occupational and environmental settings. Discussion on long- and short-term monitoring, including grab sampling, radon dosimetry, and continuous real-time monitoring, is provided. The comparative analysis of detection techniques-active versus passive-is highlighted from real-time data and long-term exposure assessment, including advances in sensor technology, data processing, and public awareness, to improve radon exposure evaluation techniques.
Topics: Radon; Humans; Occupational Exposure; Radiation Monitoring; Air Pollution, Indoor; Air Pollutants, Radioactive; Environmental Exposure
PubMed: 38793821
DOI: 10.3390/s24102966 -
Materials (Basel, Switzerland) May 2024We investigated the electronic structure of Mg-, Si-, and Zn-doped four-faceted [001]- and [110]-oriented SnO nanowires using first-principles calculations based on the...
We investigated the electronic structure of Mg-, Si-, and Zn-doped four-faceted [001]- and [110]-oriented SnO nanowires using first-principles calculations based on the linear combination of atomic orbitals (LCAO) method. This approach, employing atomic-centered Gaussian-type functions as a basis set, was combined with hybrid density functional theory (DFT). Our results show qualitative agreement in predicting the formation of stable point defects due to atom substitutions on the surface of the SnO nanowire. Doping induces substantial atomic relaxation in the nanowires, changes in the covalency of the dopant-oxygen bond, and additional charge redistribution between the dopant and nanowire. Furthermore, our calculations reveal a narrowing of the band gap resulting from the emergence of midgap states induced by the incorporated defects. This study provides insights into the altered electronic properties caused by Mg, Si, and Zn doping, contributing to the further design of SnO nanowires for advanced electronic, optoelectronic, photovoltaic, and photocatalytic applications.
PubMed: 38793261
DOI: 10.3390/ma17102193 -
American Society of Clinical Oncology... Jun 2024Lung cancer has traditionally been associated with advanced age; however, its increasing incidence among young adults raises concerning questions regarding its etiology... (Review)
Review
Lung cancer has traditionally been associated with advanced age; however, its increasing incidence among young adults raises concerning questions regarding its etiology and unique considerations for this population. In contrast to the older population, the onset of lung cancer at younger age may be attributed to a complex interplay of incompletely understood individual susceptibility and prevalent environmental risk factors beyond tobacco smoke exposure, such as radon gas and air pollution, which are widespread globally. Consequently, this leads to distinct clinical and molecular profiles, requiring a tailored approach. Furthermore, a diagnosis of cancer represents a threatening event during the prime years of a young person's life, prompting concern about career development, social aspects, fertility aspirations, and physical independence. This poses significant additional challenges for health care professionals in a field that remains underexplored. This comprehensive review recognizes lung cancer in young adults as a distinct entity, exploring its clinical and molecular characteristics, diverse predisposing factors, and priorities in terms of quality of life, with the aim of providing practical support to oncologists and enhancing our understanding of this under-researched population.
Topics: Humans; Risk Factors; Genetic Predisposition to Disease; Lung Neoplasms; Carcinoma, Non-Small-Cell Lung; Young Adult; Adult; Quality of Life
PubMed: 38788188
DOI: 10.1200/EDBK_432488 -
Open Research Europe 2024Synchrotron X-ray computed tomography is a non-destructive 3D imaging technique that offers the possibility to study the internal microstructure of samples with high...
Synchrotron X-ray computed tomography is a non-destructive 3D imaging technique that offers the possibility to study the internal microstructure of samples with high spatial and temporal resolution. Given its unmatched image quality and acquisition speed, and the possibility to preserve the specimens, there is an increasing demand for this technique, from scientific users from innumerable disciplines. Computed tomography reconstruction is the computational process by which experimental radiographs are converted to a meaningful 3-dimensional image after the scan. The procedure involves pre-processing steps for image background and artifact correction on raw data, a reconstruction step approximating the inverse Radon-transform, and writing of the reconstructed volume image to disk. Several open-source Python packages exist to help scientists in the process of tomography reconstruction, by offering efficient implementations of reconstruction algorithms exploiting central or graphics processing unit (CPU and GPU, respectively), and by automating significant portions of the data processing pipeline. A further increase in productivity is attained by scheduling and parallelizing demanding reconstructions on high performance computing (HPC) clusters. Nevertheless, visual inspection and interactive selection of optimal reconstruction parameters remain crucial steps that are often performed in close interaction with the end-user of the data. As a result, the reconstruction task involves more than one software. Graphical user interfaces are provided to the user for fast inspection and optimization of reconstructions, while HPC resources are often accessed through scripts and command line interface. We propose Alrecon, a pure Python web application for tomographic reconstruction built using Solara. Alrecon offers users an intuitive and reactive environment for exploring data and customizing reconstruction pipelines. By leveraging upon popular 3D image visualization tools, and by providing a user-friendly interface for reconstruction scheduling on HPC resources, Alrecon guarantees productivity and efficient use of resources for any type of beamline user.
PubMed: 38779342
DOI: 10.12688/openreseurope.16863.1 -
Heliyon May 2024Farmers cultivate plants in the winter using water curtain cultivation (WCC) facilities by spraying groundwater to keep them warm. In this study, the WCC facilities...
Farmers cultivate plants in the winter using water curtain cultivation (WCC) facilities by spraying groundwater to keep them warm. In this study, the WCC facilities exhibited high radon concentrations during winter. The risk varied significantly depending on the facility operation, peaking in the early morning and then decreasing upon ventilation. At all measurement sites, radon concentrations were low when groundwater was not used. Even during the period of facility groundwater use, if water vapor condensation does not occur, there is no significant difference from soil-only emissions. However, once water vapor condensation occurs, radon accumulates rapidly, depending on the degree of radon contamination in the groundwater. Because groundwater contamination varies according to dilution by regional rainfall or inflow from other regions due to groundwater movement, abnormal changes in radon content occur. We found that in the absence of water vapor condensation in the facility, all the radon emitted from the soil and groundwater quickly escaped to the atmosphere, resulting in significantly lower indoor radon concentrations. These findings pave the way for the development of new methods to mitigate radon in WCC facilities.
PubMed: 38742076
DOI: 10.1016/j.heliyon.2024.e30563 -
Journal of Environmental Radioactivity Jun 2024Radon presents significant health risks due to its short-lived progeny. The evaluation of the equivalent lung dose coefficient is crucial for assessing the potential... (Review)
Review
Radon presents significant health risks due to its short-lived progeny. The evaluation of the equivalent lung dose coefficient is crucial for assessing the potential health effects of radon exposure. This review focuses on the uncertainty analysis of the parameters associated with the calculation of the equivalent lung dose coefficient attributed to radon inhalation in mines. This analysis is complex due to various factors, such as geological conditions, ventilation rates, and occupational practices. The literature review systematically examines the sources of radon and its health effects among underground miners. It also discusses the human respiratory tract model used to calculate the equivalent lung dose coefficient and the associated parameters leading to uncertainties in the calculated lung dose. Additionally, the review covers the different methodologies employed for uncertainty quantification and their implications on dose assessment. The text discusses challenges and limitations in current research practices and provides recommendations for future studies. Accurate risk assessment and effective safety measures in mining environments require understanding and mitigating parameter uncertainties.
Topics: Radon; Mining; Humans; Occupational Exposure; Lung; Uncertainty; Air Pollutants, Radioactive; Risk Assessment; Radiation Dosage; Radiation Monitoring
PubMed: 38733660
DOI: 10.1016/j.jenvrad.2024.107446 -
Applied Radiation and Isotopes :... May 2024A liquid scintillation background sample was measured daily in a custom-built TDCR counter for more than 17 months. The double and triple coincidence counting rates...
A liquid scintillation background sample was measured daily in a custom-built TDCR counter for more than 17 months. The double and triple coincidence counting rates exhibit an annual sinusoidal fluctuation with a maximum in winter and a minimum in summer. Possible correlations with air temperature, air humidity, radon concentration and secondary cosmic radiation were investigated. The observation of a correlation with the ambient dose equivalent rate [Formula: see text] originating from the charged component of secondary cosmic radiation and an anti-correlation with the effective atmospheric temperature T suggest that the seasonal fluctuations in the background counting rate may be primarily driven by temporal variations in the muon flux at ground level. Additionally, a correlation was found with the indoor Rn concentration in air.
PubMed: 38729091
DOI: 10.1016/j.apradiso.2024.111342 -
Nanomaterials (Basel, Switzerland) Apr 2024Citrate-coated electrostatically stabilized very small superparamagnetic iron oxide particles (VSOPs) have been successfully tested as magnetic resonance angiography...
Citrate-coated electrostatically stabilized very small superparamagnetic iron oxide particles (VSOPs) have been successfully tested as magnetic resonance angiography (MRA) contrast agents and are promising tools for molecular imaging of atherosclerosis. Their repeated use in the background of pre-existing hyperlipidemia and atherosclerosis has not yet been studied. This study aimed to investigate the effect of multiple intravenous injections of VSOPs in atherosclerotic mice. Taurine-formulated VSOPs (VSOP-T) were repeatedly intravenously injected at 100 µmol Fe/kg in apolipoprotein E-deficient (ApoE KO) mice with diet-induced atherosclerosis. Angiographic imaging was carried out by in vivo MRI. Magnetic particle spectrometry was used to detect tissue VSOP content, and tissue iron content was quantified photometrically. Pathological changes in organs, atherosclerotic plaque development, and expression of hepatic iron-related proteins were evaluated. VSOP-T enabled the angiographic imaging of heart and blood vessels with a blood half-life of one hour. Repeated intravenous injection led to VSOP deposition and iron accumulation in the liver and spleen without affecting liver and spleen pathology, expression of hepatic iron metabolism proteins, serum lipids, or atherosclerotic lesion formation. Repeated injections of VSOP-T doses sufficient for MRA analyses had no significant effects on plaque burden, steatohepatitis, and iron homeostasis in atherosclerotic mice. These findings underscore the safety of VSOP-T and support its further development as a contrast agent and molecular imaging tool.
PubMed: 38727367
DOI: 10.3390/nano14090773 -
Biomedical and Environmental Sciences :... Apr 2024This study aimed to efficiently reduce the release of radon from water bodies to protect the environment.
OBJECTIVE
This study aimed to efficiently reduce the release of radon from water bodies to protect the environment.
METHODS
Based on the sizes of the experimental setup and modular float, computational fluid dynamics (CFD) was used to assess the impact of the area coverage rate, immersion depth, diffusion coefficient, and radon transfer velocity at the gas-liquid interface on radon migration and exhalation of radon-containing water. Based on the numerical simulation results, an estimation model for the radon retardation rate was constructed. The effectiveness of the CFD simulation was evaluated by comparing the experimental and simulated variation values of the radon retardation rate with the coverage area rates.
RESULTS
The effect of radon transfer velocity on radon retardation in water bodies was minor and insignificant according to the appropriate value; therefore, an estimation model of the radon retardation rate of the coverage of a radon-containing water body was constructed using the synergistic impacts of three factors: area coverage rate, immersion depth, and diffusion coefficient. The deviation between the experimental and simulated results was < 4.3%.
CONCLUSION
Based on the numerical simulation conditions, an estimation model of the radon retardation rate of covering floats in water bodies under the synergistic effect of multiple factors was obtained, which provides a reference for designing covering floats for radon retardation in radon-containing water.
Topics: Radon; Hydrodynamics; Computer Simulation; Water Pollutants, Radioactive
PubMed: 38727163
DOI: 10.3967/bes2024.026 -
ACS Omega Apr 2024The majority of uranium mill tailing impoundments in the southern part of China are located in humid subtropical regions where persistent rainfall and rapid evaporation...
The majority of uranium mill tailing impoundments in the southern part of China are located in humid subtropical regions where persistent rainfall and rapid evaporation of water after rain often occur. Under the prolonged influence of alternating wet and dry conditions, the covering soil layer of uranium mill tailing impoundments develops cracks, leading to the issue of degradation or even failure of the radon retardation effect. A beach surface of uranium mill tailing impoundments in the southern part of China is selected as the research object. Through use of a self-made simulation test device, a degradation experiment of uranium mill tailing covering soil models under wetting-drying cycles was conducted indoors. The experimental results indicate that with a constant amplitude of wetting-drying cycles, microcracks characterized by a narrow width and high abundance were mainly generated in the early-to-mid-stage of wetting-drying cycles. The main cracks, characterized by their wide width and less abundance, were mainly formed in the mid-to-late stage of wetting-drying cycles. After seven wetting-drying cycles, the total length of cracks showed a "stair-step" increase and the surface crack ratio exhibited a trend of moving from rapid growth to stable growth and then to a slight decline. The cumulative damage degree showed a rapid increase to stable growth with an increase in the number of wetting-drying cycles. Grey relational analysis revealed that, compared to other surface crack indicators, radon exhalation rate was the most closely correlated with the surface crack ratio. With a constant amplitude of wetting-drying cycles, the radon exhalation rate underwent four stages as the number of wetting-drying cycles increased: stage I witnessed a rapid increase, stage II witnessed a rapid decrease, stage III witnessed a gradual increase, and stage IV witnessed a stable or even slight decrease. With a constant number of wetting-drying cycles, the radon exhalation rate correspondingly increased with the amplitude of wetting-drying cycles, particularly noticeable when the alternation amplitude was 30 ± 20%. From the early mid-stage to the late stage of wetting-drying cycles, the curves of the radon exhalation rate, surface crack ratio, and cumulative damage degree tended to be consistent, showing a gradual increase. The research provided in this study offers valuable insights into radon control measures and environmental assessments on the beach surface of uranium mill tailing impoundments.
PubMed: 38708283
DOI: 10.1021/acsomega.4c00374