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JAAD Case Reports Apr 2024
PubMed: 38496728
DOI: 10.1016/j.jdcr.2024.02.005 -
Polish Archives of Internal Medicine Apr 2024
Topics: Humans; Male; Middle Aged; Heart Transplantation; Kidney Transplantation; Rhinophyma
PubMed: 38450599
DOI: 10.20452/pamw.16693 -
Cureus Jan 2024Gout, one of the most ancient documented diseases in history, has long captivated artists, yielding a rich collection of artworks. This interest peaked during the...
Gout, one of the most ancient documented diseases in history, has long captivated artists, yielding a rich collection of artworks. This interest peaked during the Enlightenment era in Europe, a time marked by a surge in gout cases alongside rising wealth, consumerism, and subsequent increased public access to artists. This editorial aims to highlight an intriguing observation of a novel association within several Enlightenment-era paintings depicting individuals suffering from gout and often also portraying the distinctive red noses and cheeks seen in patients with rosacea. Traditionally, both rosacea and gout have been classified as localized inflammatory diseases. However, recent studies challenge this conventional categorization, suggesting that these conditions might be components of systemic inflammatory syndromes. Despite the widespread prevalence of these conditions, their potential interconnectedness and shared pathophysiological pathways remain unexplored. Therefore, the representation of gout and rosacea in historical art could extend beyond mere artistic interest, offering a unique and critical perspective for contemporary medical research.
PubMed: 38298292
DOI: 10.7759/cureus.51438 -
Wounds : a Compendium of Clinical... Nov 2023Rosacea is a significant problem, affecting 5.5% of the world population. Currently used treatment techniques such as transfer flaps and implants are insufficient to...
BACKGROUND
Rosacea is a significant problem, affecting 5.5% of the world population. Currently used treatment techniques such as transfer flaps and implants are insufficient to meet the needs of many patients, which suggests that alternative approaches are needed.
CASE REPORT
This report describes a case of rosacea complicated by giant rhinophyma treated with excision and closure by secondary intention and growth factor application. The patient was admitted to the Department of Dermatology at The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, China, in July 2021, and underwent excision of the external nasal redundancy under general anesthesia. The postoperative wound was left open. The patient's wounds healed completely 2 months after surgery, and there was no recurrence at 6-month follow-up. The wounds recovered well, with only slight scarring.
CONCLUSION
The positive outcomes for this patient suggest that wound excision and closure by secondary intention and growth factor application may be beneficial for patients with rosacea complicated by giant rhinophyma.
Topics: Humans; Rhinophyma; Intention; Rosacea; Surgical Flaps; Intercellular Signaling Peptides and Proteins
PubMed: 38048616
DOI: 10.25270/wnds/23064 -
Postepy Dermatologii I Alergologii Oct 2023The relationship between rosacea and basal cell carcinoma (BCC) is still not known. Almost all reports questioning the relation between BCC and rosacea are focused on...
INTRODUCTION
The relationship between rosacea and basal cell carcinoma (BCC) is still not known. Almost all reports questioning the relation between BCC and rosacea are focused on rhinophyma.
AIM
To examine the possible connection of BCC and rosacea.
MATERIAL AND METHODS
110 patients with BCC located on the face treated surgically in the Dermatosurgery Unit in 2020-2021 were included in the study. A trained dermatologist assessed the presence or absence of concomitant rosacea and assessed its severity according to the Investigator's Global Assessment (IGA).
RESULTS
Fifty-one (46.4%) subjects with BCC and concomitant clinically diagnosed rosacea were found. In our group 35.5% of women had BCC located on the cheeks, while in men most cancers were located on the nose (55%, = 11), however this difference has not reached statistical significance.
CONCLUSIONS
The incidence of rosacea in our population was undoubtedly higher, comparing to the normative population. Both rosacea and BCC share the same risk factors - UV exposure, the potential association should not be neglected.
PubMed: 38028413
DOI: 10.5114/ada.2023.130523 -
JPRAS Open Dec 2023Rhinophyma is a benign condition caused by the excessive growth of sebaceous glands in the nasal tissue, presenting with symptoms such as nasal hypertrophy, erythema,...
BACKGROUND
Rhinophyma is a benign condition caused by the excessive growth of sebaceous glands in the nasal tissue, presenting with symptoms such as nasal hypertrophy, erythema, and papules. Cases of basal cell carcinoma in rhinophyma have been reported in literature, but its etiological role remains unclear. It is uncertain whether rhinophyma is predisposed to neoplasm development or if their coexistence is coincidental.
MATERIAL AND METHOD
We conducted a literature survey to identify such cases reported over the years.
RESULTS
We identified 22 studies reporting a total of 47 cases in the literature, all involving male patients. The most common pattern of occurrence was the rapid growth of a nodular formation within the context of rhinophyma.
DISCUSSIONS AND CONCLUSION
The elucidation of the association between basal cell carcinoma and rhinophyma remains challenging. The presence of multiple foci supports the theory that rhinophyma may play a role in their development, but larger studies are needed to establish a causal relationship.
PubMed: 37920281
DOI: 10.1016/j.jpra.2023.10.001 -
Clinical, Cosmetic and Investigational... 2023Cutaneous metastasis is rare in clinical practice, especially that from primary hepatocellular carcinoma (HCC), which is even rarer.
BACKGROUND
Cutaneous metastasis is rare in clinical practice, especially that from primary hepatocellular carcinoma (HCC), which is even rarer.
CASE PRESENTATION
This report describes a male patient with HCC with cutaneous metastases to the nasal tip. The patient developed a raised nodule at the nasal tip 5 years after surgery for HCC, with surface ulceration and crusting and no obvious symptoms. Abdominal computed tomography (CT) showed an obvious mass in the liver. The skin lesions on the nasal tip were confirmed to be cutaneous metastasis of HCC by histopathological and immunohistochemical examinations.
CONCLUSION
The incidence of cutaneous metastasis of HCC is extremely low, and nasal tip cutaneous metastasis of HCC has no specific clinical manifestations; therefore, it needs to be distinguished from rosacea rhinophyma, fungal and atypical mycobacterial infections, tumours of vascular origin, and tumours of skin appendages that occur in the nasal tip and is prone to misdiagnosis and missed diagnosis, thus requiring clinical dermatologists and otolaryngologists to be aware of such metastasis.
PubMed: 37869532
DOI: 10.2147/CCID.S429480 -
Skin Research and Technology : Official... Aug 2023The Flash-lamp pulsed dye laser (FPDL) is nowadays considered the most precise laser currently on the market for treating superficial vascular lesions. In this study, we...
INTRODUCTION
The Flash-lamp pulsed dye laser (FPDL) is nowadays considered the most precise laser currently on the market for treating superficial vascular lesions. In this study, we gathered data from 10 years of experience regarding dye laser treatment of patients presenting vascular malformations such as telangiectasia, rhinophyma, port-wine stain, cherry and spider angioma and vascular tumours.
METHODS
Subjects were enrolled from 2013 to 2023 based on the vascular anomalies they presented. They underwent different treatment sessions with the FPDL device.
RESULTS
The age-range distribution by vascular anomaly confirmed that haemangiomas are typical in children while rhinophyma is a condition very common in older adults. A difference in sex distribution showed that pathologies such as telangiectasias typically affect women whereas rhinophyma is more frequent in men. Most of the treatments interested the face area but no permanent side effects were registered.
CONCLUSIONS
Our 10 years of experience with FPDL demonstrated good results in a wide range of applications for the treatment of different vascular anomalies. The absence of long-term side effects and bearable pain during the treatment makes it a valuable solution for the resolution of benign tumours also in very young patients.
Topics: Female; Humans; Male; Lasers, Dye; Retrospective Studies; Rhinophyma; Hemangioma; Vascular Malformations
PubMed: 37632184
DOI: 10.1111/srt.13427 -
Skin Research and Technology : Official... Jul 2023
Topics: Humans; Electrosurgery; Radio Waves; Rhinophyma; Male; Aged
PubMed: 37522510
DOI: 10.1111/srt.13409