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The Primary Care Companion For CNS... Jan 2017
Topics: Antipsychotic Agents; Female; Humans; Meige Syndrome; Middle Aged; Paliperidone Palmitate; Psychotic Disorders
PubMed: 28129491
DOI: 10.4088/PCC.16l01997 -
Journal of Neurology, Neurosurgery, and... Mar 1983
Topics: Adult; Basal Ganglia Diseases; Chorea; Dose-Response Relationship, Drug; Female; Humans; Levodopa
PubMed: 6842240
DOI: 10.1136/jnnp.46.3.286 -
Asian Journal of Surgery May 2024
PubMed: 38824021
DOI: 10.1016/j.asjsur.2024.05.156 -
Journal of Pain and Symptom Management Jul 1992Patients with prodromal neuralgia associated with recurrent herpes simplex type 1 (HST1) infection and chronic facial pain following years of relapsing HST1 have been...
Patients with prodromal neuralgia associated with recurrent herpes simplex type 1 (HST1) infection and chronic facial pain following years of relapsing HST1 have been described. Chronic neuralgia following a single clinical HST1 infection and simulating postherpetic neuralgia has not been previously reported. Such a case is described: A 49-yr-old woman with a 2-mo history of oral-facial dyskinesia developed burning pain and hypersensitivity of the left side of the tongue, lower gum, and inner cheek, followed 1 day later by a vesicular rash in the same painful distribution. Viral cultures of the lesions identified HST1 but not herpes zoster. Cerebrospinal fluid analyses during the vesicular lesion stage and 1 mo later were normal with no viral growth. Oral and facial lesions resolved after 10 days; acyclovir was given for 3 wk. Brain and brainstem magnetic resonance imaging (MRI), electroencephalogram, and brainstem evoked potential studies were normal. Hyperesthesias, allodynia, and burning pain persisted despite nonsteroidal antiinflammatory agents, codeine and hydrocodone. Oral opioids were administered until sedation occurred, with no relief of pain. The burning pain and hyperesthesia resolved after the 16th day of amitriptyline use, 75 mg/day. A trial off amitriptyline 6 mo later resulted in recurrence of pain, and amitriptyline was restarted with good pain control. Post-HST1 neuralgia may simulate postherpetic neuralgia clinically, and painful symptoms may respond to amitriptyline.
Topics: Amitriptyline; Chronic Disease; Diagnosis, Differential; Female; Herpes Simplex; Herpes Zoster; Humans; Meige Syndrome; Middle Aged; Neuralgia
PubMed: 1624816
DOI: 10.1016/0885-3924(92)90065-p -
Journal of Neurology, Neurosurgery, and... Mar 2003To study the reliability of the diagnosis of blepharospasm, oromandibular dystonia, cervical dystonia, and writer's cramp among neurologists.
OBJECTIVE
To study the reliability of the diagnosis of blepharospasm, oromandibular dystonia, cervical dystonia, and writer's cramp among neurologists.
METHODS
12 patients with adult onset focal segmental dystonia were videotaped in a standardised way. The tape was sent to six neurologists who are involved in clinical practice without a specific interest in movement disorders (general neurologists), and to four neurologists expert in movement disorders. The observers had to recognise whether the patients were affected by dystonia and to distinguish among blepharospasm, oromandibular dystonia, cervical dystonia, and writer's cramp. Interobserver reliability was assessed by kappa statistics, and the degree of agreement was classified according to the Landis classification.
RESULTS
The 10 neurologists reached slight to moderate agreement on the diagnosis of these four disorders. When the observers were subdivided according with their professional experience in the field, a moderate to perfect agreement on the diagnosis was achieved by specialists in movement disorders, and a fair to moderate agreement by the general neurologists.
CONCLUSIONS
Neurologists may have different ability to recognise adult onset focal dystonia, depending on their experience and on the type of dystonia.
Topics: Adult; Aged; Cooperative Behavior; Diagnosis, Differential; Dystonic Disorders; Female; Humans; Male; Meige Syndrome; Middle Aged; Torticollis
PubMed: 12588923
DOI: 10.1136/jnnp.74.3.348 -
The British Journal of Ophthalmology Dec 1991To determine the long-term efficacy of botulinum toxin injections for the treatment of facial dyskinesias we studied 50 consecutive patients with blepharospasm,...
To determine the long-term efficacy of botulinum toxin injections for the treatment of facial dyskinesias we studied 50 consecutive patients with blepharospasm, hemifacial spasm, and Meige syndrome. All received their first injection between September 1983 and June 1984. A total of 520 injections were given; the average number of injections per patient was 10.4 over the seven-year period ending September 1990. Twenty-six (52%) of the patients continued to return for periodic injections, while three patients no longer receive injections since they failed to respond adequately to treatment. Three patients with blepharospasm were in remission and required no further treatment, after a series of six, four, and three injections. Six patients were treated until they died of causes unrelated to facial dyskinesia or its treatment. Six patients are still being treated elsewhere because they could obtain injections closer to their homes. Five of the original 50 patients have been lost to follow-up. A patient with hemifacial spasm had one injection with good result but was not sufficiently bothered by her disease to return for reinjection. Complications were transient, minimal, well tolerated, and did not increase with increased number of injections.
Topics: Adult; Aged; Blepharospasm; Botulinum Toxins; Facial Muscles; Female; Follow-Up Studies; Humans; Male; Meige Syndrome; Middle Aged; Spasm
PubMed: 1768664
DOI: 10.1136/bjo.75.12.737 -
Journal of Neurology, Neurosurgery, and... Apr 1989A family is reported in which three generations were affected with eye-winking tics and/or blepharospasm. The proband developed eye-winking tics in childhood and then...
A family is reported in which three generations were affected with eye-winking tics and/or blepharospasm. The proband developed eye-winking tics in childhood and then developed excessive blinking progressing to blepharospasm by the age of 21 years. His mother presented with Meige's syndrome and spasmodic torticollis at the age of 59 years; his uncle had blinked excessively from his early forties. His eldest son developed an eye-winking tic with facial grimacing at the age of 8 years, and in another son, a self-limiting period of eye-blinking occurred at the age of 4 years. The recovery cycle of the blink reflex was abnormal in all three generations. Three other children with eye-winking tics have a parent or close relative with frequent eye-blinking or blepharospasm. Five patients with adult-onset blepharospasm or Meige's syndrome are also described who had excessive eye-blinking dating back to childhood. It is suggested that eye-winking tics, frequent blinking and blepharospasm may share common pathophysiological mechanisms; the clinical expression may be age-related.
Topics: Adolescent; Adult; Blepharospasm; Blinking; Child; Dystonia; Eyelid Diseases; Female; Humans; Male; Middle Aged; Pedigree; Tic Disorders
PubMed: 2738590
DOI: 10.1136/jnnp.52.4.477 -
Internal Medicine (Tokyo, Japan) 2011
Topics: Clonazepam; Dysphonia; Electromyography; GABA Modulators; Humans; Male; Meige Syndrome; Middle Aged; Treatment Outcome
PubMed: 21921402
DOI: 10.2169/internalmedicine.50.5812 -
British Medical Journal (Clinical... Jun 1985Botulinum toxin type A creates temporary localised flaccid paralysis after injection into skeletal muscle. Thirty four patients with blepharospasm, of whom 28 also had...
Botulinum toxin type A creates temporary localised flaccid paralysis after injection into skeletal muscle. Thirty four patients with blepharospasm, of whom 28 also had the oromandibular dystonia syndrome, were treated with injections of botulinum toxin type A into the orbicularis oculi, and 28 showed functional improvement after the treatment. A high incidence of local side effects occurred, especially partial ptosis, which was well tolerated. There were no systemic side effects. The average period of relief was 2.5 months, increasing to 2.8 months after a second injection. Functional improvement was limited in patients with severe associated dystonia.
Topics: Adult; Aged; Blepharospasm; Botulinum Toxins; Eyelid Diseases; Female; Humans; Male; Meige Syndrome; Middle Aged
PubMed: 3924284
DOI: 10.1136/bmj.290.6485.1857 -
Journal of Pediatric Neurosciences 2016Japanese encephalitis (JE) is a mosquito borne encephalitis caused by Flavivirus. Neurocysticercosis (NCC) is a parasitic disease of the central nervous system caused by...
Japanese encephalitis (JE) is a mosquito borne encephalitis caused by Flavivirus. Neurocysticercosis (NCC) is a parasitic disease of the central nervous system caused by Taenia solium. In this report, we describe the clinical profile, imaging findings, and outcome of two children with JE and coexisting NCC. Eleven and thirteen-year-old boys from the same town of Jharkhand state were brought with history of fever, seizures, altered sensorium, and extrapyramidal symptoms. Dystonia, hypomimia, bradykinesia, and dyskinesia were observed. Meige syndrome observed in one of the children is a novel finding. Magnetic resonance imaging of the brain revealed findings suggestive of JE with cysticercal granulomas. There are few reports of coexistence of JE and NCC in children. Both children were treated with ribavirin, and follow-up imaging had shown significant resolution of signal changes. Both the children had shown marked clinical improvement. Ribavirin was found to beneficial in reducing the morbidity in our patients.
PubMed: 27606026
DOI: 10.4103/1817-1745.187644