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Journal of Veterinary Internal Medicine 1991Permanent transvenous cardiac pacemakers were implanted in 40 dogs. Electrocardiographic diagnoses included persistent atrial standstill (3 dogs), sick sinus syndrome (8...
Permanent transvenous cardiac pacemakers were implanted in 40 dogs. Electrocardiographic diagnoses included persistent atrial standstill (3 dogs), sick sinus syndrome (8 dogs), and high-grade second-degree or third-degree atrioventricular (AV) block (29 dogs). Thirteen dogs were alive and well 4 to 42 months after pacemaker implantation (mean, 16.9 months). The mean and median survival times of the 26 dogs that died or were euthanatized during the study were 17.9 months and 13 months, respectively. Most of these dogs succumbed to problems unrelated to the arrhythmia and pacemaker implant. One dog was lost to follow-up. Complications associated with permanent transvenous pacemaker implantation included lead dislodgement, infection, hematoma formation, skeletal muscle stimulation, ventricular arrhythmia, migration of the pulse generator, and skin erosion. Lead dislodgement was the most common complication, occurring in 7 of 9 dogs paced using untined electrode leads and in 6 of 30 dogs paced using tined leads. Lead dislodgement did not occur in the only dog paced using an actively fixed endocardial lead. It was concluded that permanent transvenous cardiac pacing is a feasible, less traumatic alternative to epimyocardial pacing in dogs, but that successful use of this technique requires careful implantation technique and anticipation of the potential complications.
Topics: Animals; Arrhythmias, Cardiac; Bradycardia; Dog Diseases; Dogs; Electrocardiography; Female; Follow-Up Studies; Male; Pacemaker, Artificial; Postoperative Complications; Reoperation; Surgical Wound Infection; Treatment Outcome
PubMed: 1779425
DOI: 10.1111/j.1939-1676.1991.tb03145.x -
British Heart Journal Nov 1995Thrombus formation in the left atrium is rare in patients in sinus rhythm. In three patients with extensive cardiac amyloidosis transthoracic echocardiography showed...
Thrombus formation in the left atrium is rare in patients in sinus rhythm. In three patients with extensive cardiac amyloidosis transthoracic echocardiography showed large atrial thrombi in or protruding into the body of the left atrium during sinus rhythm. Doppler studies showed no A wave on mitral inflow. Severe atrial and ventricular infiltration by amyloid may have resulted in mechanical atrial standstill with resultant thrombus formation. These findings suggest that patients with severe cardiac amyloidosis may require anticoagulation when atrial function is impaired.
Topics: Adult; Amyloidosis; Atrial Function; Cardiomyopathies; Fatal Outcome; Female; Heart Atria; Humans; Middle Aged; Sinoatrial Node; Thrombosis; Ultrasonography
PubMed: 8562243
DOI: 10.1136/hrt.74.5.541 -
Journal of Veterinary Internal Medicine 1992Hyperkalemia has been associated with cardiac abnormalities and muscular disorders. Hyperkalemia is a common problem associated with the acid-base and electrolyte...
Hyperkalemia has been associated with cardiac abnormalities and muscular disorders. Hyperkalemia is a common problem associated with the acid-base and electrolyte disturbances that occur in neonatal calves having acute diarrhea. Occasional calves with acute neonatal diarrhea, metabolic acidosis, and hyperkalemia have cardiac rate or rhythm abnormalities. Bradycardia observed in three such calves was found to represent atrial standstill and was attributed to hyperkalemia.
Topics: Animals; Animals, Newborn; Bradycardia; Cattle; Cattle Diseases; Dehydration; Diarrhea; Electrocardiography; Female; Fluid Therapy; Heart Atria; Heart Rate; Hyperkalemia; Male
PubMed: 1432903
DOI: 10.1111/j.1939-1676.1992.tb00354.x -
The Canadian Veterinary Journal = La... Mar 2016Pacemakers were implanted in 4 client-owned female dogs which had persistent atrial standstill. Three dogs were alive after 14 to 39 months and 1 dog was euthanized...
Pacemakers were implanted in 4 client-owned female dogs which had persistent atrial standstill. Three dogs were alive after 14 to 39 months and 1 dog was euthanized after 10.5 years. This report demonstrates that some dogs with persistent atrial standstill can survive for extended time periods.
Topics: Animals; Cardiomyopathies; Dog Diseases; Dogs; Female; Genetic Diseases, Inborn; Heart Atria; Heart Block; Pacemaker, Artificial; Survival Rate; Treatment Outcome
PubMed: 26933268
DOI: No ID Found -
HeartRhythm Case Reports Aug 2018
PubMed: 30116708
DOI: 10.1016/j.hrcr.2018.04.015 -
The American Journal of Cardiology Jun 1982
Topics: Adult; Arrhythmias, Cardiac; Cerebrovascular Disorders; Echocardiography; Electrocardiography; Heart Atria; Humans; Male; Muscular Dystrophies; Myocardial Contraction; Neuromuscular Diseases; Syncope; Vertigo
PubMed: 7081083
DOI: 10.1016/0002-9149(82)90226-0 -
Circulation Journal : Official Journal... Dec 2002A 59-year-old woman with partial atrial standstill was studied using magnetocardiograms (MCGs), which revealed through QRS-T subtraction and time-frequency analysis that...
A 59-year-old woman with partial atrial standstill was studied using magnetocardiograms (MCGs), which revealed through QRS-T subtraction and time-frequency analysis that there was a high-frequency (6 Hz) magnetic source at the low atrial septum. MCGs are useful for noninvasively evaluating the clinical course of patients with atrial fibrillation.
Topics: Algorithms; Atrial Fibrillation; Atrial Function; Electrocardiography; Female; Heart Arrest; Heart Septum; Humans; Magnetics; Middle Aged; Subtraction Technique
PubMed: 12499629
DOI: 10.1253/circj.66.1178 -
Journal of Internal Medicine Jan 2004Mutations in the cardiac Na+ channel gene SCN5A are responsible for multiple lethal ventricular arrhythmias including Brugada syndrome and congenital long QT syndrome....
Mutations in the cardiac Na+ channel gene SCN5A are responsible for multiple lethal ventricular arrhythmias including Brugada syndrome and congenital long QT syndrome. Here we report a case of Brugada syndrome with ST elevation in the right precordial and inferior leads accompanied by atrial standstill and spontaneous ventricular fibrillation. Atrial standstill and J wave elevation were provoked by procainamide. Genetic analysis revealed a missense mutation (R367H) in SCN5A. The resultant mutant Na+ channel was nonfunctional when expressed heterologously in Xenopus oocytes. Our study suggests that genetic defects in SCN5A may be associated with atrial standstill in combination with ventricular arrhythmias.
Topics: Adult; Electrocardiography; Female; Heart; Heart Atria; Heart Function Tests; Humans; Mutation, Missense; Myocardium; NAV1.5 Voltage-Gated Sodium Channel; Polymerase Chain Reaction; Sodium Channels; Syndrome; Ventricular Fibrillation
PubMed: 14687250
DOI: 10.1046/j.0954-6820.2003.01247.x -
The Tohoku Journal of Experimental... Sep 1988The cardiac and coronary effects of AN-132, a new antiarrhythmic agent, were investigated in isolated, blood-perfused atrioventricular (AV) node, sinoatrial (SA) node...
The cardiac and coronary effects of AN-132, a new antiarrhythmic agent, were investigated in isolated, blood-perfused atrioventricular (AV) node, sinoatrial (SA) node and papillary muscle preparations of dogs. AN-132 was administered intraarterially. In AV node preparations, whether injected into the anterior septal artery (ASA; supplying the His-Purkinje-ventricular system) or the posterior septal artery (PSA; supplying the AV node), AN-132 prolonged AV conduction time and produced second- or third-degree AV block at large doses in some preparations. Moreover, only when injected into the ASA AN-132 produced a broadening and diminution of amplitude of bipolar electrograms obtained from the right bundle branch and the ventricular septum. In SA node preparations, AN-132 decreased sinus rate and produced atrial standstill at large doses in some preparations. In paced papillary muscle preparations, AN-132 reduced the force of contraction. In spontaneously beating papillary muscle preparations, AN-132 decreased the rate of automaticity and the force of contraction. In all preparations, AN-132 produced a transient increase in blood flow only at large doses. The order of potencies of AN-132 based on the doses that produced 15% suppressions of the above cardiovascular variables was as follows: cardiac muscle contraction greater than ventricular automaticity greater than or equal to intraventricular conduction greater than AV nodal conduction greater than or equal to coronary blood flow greater than SA nodal automaticity.
Topics: Anilides; Animals; Dogs; Dose-Response Relationship, Drug; Ethylenediamines; Heart; Heart Conduction System; Heart Rate; In Vitro Techniques; Injections, Intra-Arterial; Myocardial Contraction; Perfusion
PubMed: 3194907
DOI: 10.1620/tjem.156.65 -
The Canadian Veterinary Journal = La... Oct 2002An Ibizan hound cross was referred with a 1-year history of syncope and exercise intolerance. An electrocardiogram showed bradycardia and no P waves; atrial standstill...
An Ibizan hound cross was referred with a 1-year history of syncope and exercise intolerance. An electrocardiogram showed bradycardia and no P waves; atrial standstill was diagnosed. A permanent artificial endocardial pacemaker was implanted. The lead dislodged and was reimplanted into the right ventricular apex. Capture was once again achieved.
Topics: Animals; Bradycardia; Cardiac Pacing, Artificial; Dog Diseases; Dogs; Electrocardiography; Female; Pacemaker, Artificial
PubMed: 12395764
DOI: No ID Found